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Extract from the Register of European Patents

EP About this file: EP1328526

EP1328526 - 3,8-DIAZABICYCLO 3.2.1 OCTANES AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS [Right-click to bookmark this link]
Former [2003/30]3,8-DIAZABICYCLO[3.2.1]OCTANES AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS
[2007/45]
StatusThe application has been refused
Status updated on  21.07.2006
Database last updated on 22.08.2024
Most recent event   Tooltip05.10.2007Change - German titlepublished on 07.11.2007  [2007/45]
Applicant(s)For all designated states
AstraZeneca AB
151 85 Södertälje / SE
[2003/30]
Inventor(s)01 / BJÖRSNE, Magnus
AstraZeneca R & D Mölnda
S-431 83 Mölndal / SE
02 / HOFFMANN, Kurt-Jürgen
AstraZeneca R & D Mölndal
S-431 83 Mölndal / SE
03 / PONTEN, Fritiof
AstraZeneca R & D Mölndal
S-431 83 Mölndal / SE
04 / STRANDLUND, Gert
AstraZeneca R & D Mölndal
S-431 83 Mölndal / SE
05 / SVENSSON, Peder
Nordenskiöldsgatan 12
S-413 09 Göteborg / SE
06 / WILSTERMANN, Michael
AstraZeneca R & D Mölndal
S-431 83 Mölndal / SE
 [2003/30]
Application number, filing date01977023.918.10.2001
[2003/30]
WO2001SE02294
Priority number, dateSE2000000379520.10.2000         Original published format: SE 0003795
[2003/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0232902
Date:25.04.2002
Language:EN
[2002/17]
Type: A1 Application with search report 
No.:EP1328526
Date:23.07.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 25.04.2002 takes the place of the publication of the European patent application.
[2003/30]
Search report(s)International search report - published on:SE25.04.2002
ClassificationIPC:C07D487/08, A61K31/495, A61P9/06
[2003/30]
CPC:
C07D487/08 (EP,US); A61K31/495 (EP,US); A61P9/06 (EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/30]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:3,8-DIAZABICYCLO 3.2.1 OCTANE UND DEREN VERWENDUNG BEI DER BEHANDLUNG VON HERZRHYTHMUSSTÖRUNGEN[2007/45]
English:3,8-DIAZABICYCLO 3.2.1 OCTANES AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS[2007/45]
French:3,8-DIAZABICYCLO 3.2.1 OCTANES ET LEUR UTILISATION DANS LE TRAITEMENT D'ARYTHMIES CARDIAQUES[2007/45]
Former [2003/30]3,8-DIAZABICYCLO[3.2.1]OCTANE UND DEREN VERWENDUNG BEI DER BEHANDLUNG VON HERZRHYTHMUSSTÖRUNGEN
Former [2003/30]3,8-DIAZABICYCLO[3.2.1]OCTANES AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS
Former [2003/30]3,8-DIAZABICYCLO[3.2.1]OCTANES ET LEUR UTILISATION DANS LE TRAITEMENT D'ARYTHMIES CARDIAQUES
Entry into regional phase20.05.2003National basic fee paid 
20.05.2003Designation fee(s) paid 
20.05.2003Examination fee paid 
Examination procedure15.05.2002Request for preliminary examination filed
International Preliminary Examining Authority: SE
20.05.2003Examination requested  [2003/30]
17.02.2005Despatch of a communication from the examining division (Time limit: M06)
26.08.2005Reply to a communication from the examining division
01.03.2006Cancellation of oral proceeding that was planned for 10.03.2006
01.03.2006Minutes of oral proceedings despatched
10.03.2006Date of oral proceedings (cancelled)
10.04.2006Despatch of communication that the application is refused, reason: substantive examination [2006/34]
20.04.2006Application refused, date of legal effect [2006/34]
Fees paidRenewal fee
31.10.2003Renewal fee patent year 03
02.11.2004Renewal fee patent year 04
31.10.2005Renewal fee patent year 05
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Cited inInternational search[X]WO9518129  (PFIZER [US], et al);
 [X]WO0059510  (PFIZER PROD INC [US], et al);
 [A]WO9523152  (RIACE ETS [LI], et al);
 [A]WO9635686  (RHONE POULENC RORER SA [FR], et al)
 [A]  - G. CIGNARELLA ET AL., "Benzocondensed derivatives as rigid analogues of the mu-opioid agonist 3(8)-cinnamyl-8(3)-propionyl-3,8-diazabicyclo(3.2.1)octanes: Synthesis, modeling and affinity", II FARMACO, (1998), vol. 53, pages 667 - 674, XP002906803

DOI:   http://dx.doi.org/10.1016/S0014-827X(98)00084-6
 [A]  - DANIELA BARLOCCO ET AL., "Mono- and disubstituted-3,8-diazabicyclo(3.2.1)octane derivatives as analgesics structurally related to epibatidine: Synthesis, activity and modeling", J. MED. CHEM., (1998), vol. 41, pages 674 - 681, XP002906804

DOI:   http://dx.doi.org/10.1021/jm970427p
 [A]  - D. BARLOCCO ET AL., "Synthesis and mu-opioid receptor affinity of a new series of nitro substituted 3,8-diazabicyclo(3.2.1)octane derivatives", II FARMACO, (1998), vol. 53, pages 557 - 562, XP002906805

DOI:   http://dx.doi.org/10.1016/S0014-827X(98)00065-2
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.