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Extract from the Register of European Patents

EP About this file: EP1351702

EP1351702 - Trem-1 splice variant for use in modifying immune responses [Right-click to bookmark this link]
Former [2003/42]TREM-1 SPLICE VARIANT FOR USE IN MODIFYING IMMUNE RESPONSES
[2014/27]
StatusNo opposition filed within time limit
Status updated on  08.01.2016
Database last updated on 29.03.2025
Most recent event   Tooltip13.10.2017Lapse of the patent in a contracting statepublished on 15.11.2017  [2017/46]
Applicant(s)For all designated states
Bioprovar Corporation
8027 Oakington Drive
Houston TX 77071 / US
[2014/01]
Former [2007/16]For all designated states
GenePrint Corporation
8027 Oakington Drive
Houston TX 77071 / US
Former [2003/42]For all designated states
BAYLOR COLLEGE OF MEDICINE
One Baylor Plaza
Houston, TX 77030 / US
Inventor(s)01 / MARGOLIN, Judith, F.
5326 Dumfries
Houston, TX 77096 / US
02 / GINGRAS, Marie-Claude
8027 Oakington Drive
Houston, TX 77071-77030 / US
 [2007/16]
Former [2003/42]01 / MARGOLIN, Judith, F.
5326 Dumfries
Houston, TX 77096 / US
02 / GINGRAS, Marie-Claude
8027 Oakington Dr.
Houston, TX 77071-77030 / US
Representative(s)Nederlandsch Octrooibureau
P.O. Box 29720
2502 LS The Hague / NL
[2013/28]
Former [2013/23]Swinkels, Bart Willem
Nederlandsch Octrooibureau P.O. Box 29720
2502 LS Den Haag / NL
Former [2012/43]Vossius & Partner
P.O. Box 86 07 67
81634 München / DE
Former [2009/22]Swinkels, Bart Willem
Nederlandsch Octrooibureau P.O. Box 29720
2502 LS Den Haag / NL
Former [2008/23]Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Leopoldstrasse 4
80802 München / DE
Former [2008/21]Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Leopoldstrasse 4
80802 München / DE
Former [2006/01]Vogelsang-Wenke, Heike
Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät Maximilianstrasse 58
80538 München / DE
Former [2003/42]Woods, Geoffrey Corlett, et al
J.A. KEMP & CO. Gray's Inn 14 South Square
London WC1R 5JJ / GB
Application number, filing date01994219.207.12.2001
[2003/42]
WO2001US48126
Priority number, dateUS20000254404P08.12.2000         Original published format: US 254404 P
[2003/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO02058721
Date:01.08.2002
Language:EN
[2002/31]
Type: A1 Application with search report 
No.:EP1351702
Date:15.10.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 01.08.2002 takes the place of the publication of the European patent application.
[2003/42]
Type: B1 Patent specification 
No.:EP1351702
Date:04.03.2015
Language:EN
[2015/10]
Search report(s)International search report - published on:US01.08.2002
(Supplementary) European search report - dispatched on:EP01.07.2004
ClassificationIPC:A61K38/16, A61K38/17, A61K38/18, C07K14/705, C07K14/71, C07K14/715, G01N33/53, G01N33/566, G01N33/68, G01N33/564, A61K38/00, G01N33/569
[2014/27]
CPC:
G01N33/56966 (EP,US); A61P17/02 (EP); A61P19/02 (EP);
A61P19/08 (EP); A61P29/00 (EP); A61P31/00 (EP);
A61P31/04 (EP); A61P37/06 (EP); A61P43/00 (EP);
C07K14/70503 (EP,US); G01N33/564 (EP,US); G01N33/566 (EP,US);
G01N33/6893 (EP,US); A61K38/00 (EP,US); G01N2333/70503 (EP,US) (-)
Former IPC [2003/42]A61K38/16, A61K38/17, A61K38/18, C07K14/705, C07K14/71, C07K14/715, G01N33/53
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/42]
Extension statesAL08.07.2003
LT08.07.2003
LV08.07.2003
MK08.07.2003
RO08.07.2003
SI08.07.2003
TitleGerman:Trem-1-Spleissvariante zur Modifikation von Immunreaktionen[2014/27]
English:Trem-1 splice variant for use in modifying immune responses[2014/27]
French:Variant d'épissage de Trem-1 utile pour modifier des réactions immunitaires[2014/27]
Former [2003/42]TREM-1-SPLEISSVARIANTE ZUR MODIFIKATION VON IMMUNREAKTIONEN
Former [2003/42]TREM-1 SPLICE VARIANT FOR USE IN MODIFYING IMMUNE RESPONSES
Former [2003/42]VARIANT D'EPISSAGE DE TREM-1 UTILE POUR MODIFIER DES REACTIONS IMMUNITAIRES
Entry into regional phase08.07.2003National basic fee paid 
08.07.2003Search fee paid 
08.07.2003Designation fee(s) paid 
08.07.2003Examination fee paid 
Examination procedure08.07.2002Request for preliminary examination filed
International Preliminary Examining Authority: US
08.07.2003Amendment by applicant (claims and/or description)
08.07.2003Examination requested  [2003/42]
07.02.2005Despatch of a communication from the examining division (Time limit: M06)
02.12.2005Reply to a communication from the examining division
31.01.2006Despatch of a communication from the examining division (Time limit: M06)
04.10.2006Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
07.11.2006Reply to a communication from the examining division
19.02.2007Despatch of a communication from the examining division (Time limit: M06)
31.08.2007Reply to a communication from the examining division
10.04.2008Cancellation of oral proceeding that was planned for 15.04.2008
10.04.2008Minutes of oral proceedings despatched
15.04.2008Date of oral proceedings
15.04.2008Date of oral proceedings (cancelled)
28.05.2008Despatch of communication that the application is refused, reason: substantive examination {1}
15.01.2009Observations by third parties
12.03.2013Despatch of a communication from the examining division (Time limit: M06)
12.08.2013Reply to a communication from the examining division
10.01.2014Despatch of a communication from the examining division (Time limit: M04)
17.03.2014Reply to a communication from the examining division
03.06.2014Communication of intention to grant the patent
08.09.2014Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
26.09.2014Communication of intention to grant the patent
20.01.2015Fee for grant paid
20.01.2015Fee for publishing/printing paid
20.01.2015Receipt of the translation of the claim(s)
Appeal following examination07.08.2008Appeal received No.  T2181/08
07.10.2008Statement of grounds filed
14.11.2012Result of appeal procedure: remittal for grant
14.11.2012Date of oral proceedings
20.11.2012Minutes of oral proceedings despatched
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  07.02.2005
Opposition(s)07.12.2015No opposition filed within time limit [2016/06]
Request for further processing for:07.11.2006Request for further processing filed
07.11.2006Full payment received (date of receipt of payment)
Request granted
23.11.2006Decision despatched
02.12.2005Request for further processing filed
02.12.2005Full payment received (date of receipt of payment)
Request granted
28.12.2005Decision despatched
Fees paidRenewal fee
12.12.2003Renewal fee patent year 03
14.12.2004Renewal fee patent year 04
15.12.2005Renewal fee patent year 05
13.12.2006Renewal fee patent year 06
05.06.2008Renewal fee patent year 07
23.12.2008Renewal fee patent year 08
31.12.2009Renewal fee patent year 09
29.12.2010Renewal fee patent year 10
30.12.2011Renewal fee patent year 11
31.12.2012Renewal fee patent year 12
18.12.2013Renewal fee patent year 13
11.12.2014Renewal fee patent year 14
Penalty fee
Additional fee for renewal fee
31.12.200707   M06   Fee paid on   05.06.2008
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT04.03.2015
CY04.03.2015
DK04.03.2015
ES04.03.2015
FI04.03.2015
IT04.03.2015
TR04.03.2015
GR05.06.2015
PT06.07.2015
[2017/46]
Former [2017/40]AT04.03.2015
CY04.03.2015
DK04.03.2015
ES04.03.2015
FI04.03.2015
IT04.03.2015
TR04.03.2015
GR05.06.2015
PT06.07.2015
Former [2016/07]AT04.03.2015
DK04.03.2015
ES04.03.2015
FI04.03.2015
IT04.03.2015
GR05.06.2015
PT06.07.2015
Former [2016/03]AT04.03.2015
ES04.03.2015
FI04.03.2015
IT04.03.2015
GR05.06.2015
PT06.07.2015
Former [2015/49]AT04.03.2015
ES04.03.2015
FI04.03.2015
GR05.06.2015
PT06.07.2015
Former [2015/38]AT04.03.2015
ES04.03.2015
FI04.03.2015
GR05.06.2015
Former [2015/37]ES04.03.2015
FI04.03.2015
GR05.06.2015
Former [2015/36]ES04.03.2015
FI04.03.2015
Former [2015/33]ES04.03.2015
Documents cited:Search[X]WO9906557  (SCHERING CORP [US]) [X] 1,2,4,9,10,14-17,26 * page 25, line 21 - line 27 * * page 54, line 9 - page 55, line 24 * * page 56, line 19 - line 30 *;
 [A]EP1022286  (ONO PHARMACEUTICAL CO [JP]) [A] 1-26 * Sequence with ID No 22 and 23; page 9, paragraph 78 *;
 [DX]  - BOUCHON A ET AL, Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes., JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 15 MAY 2000, VOL. 164, NR. 10, PAGE(S) 4991 - 4995, (20000515), ISSN 0022-1767, XP002951620 [DX] 1-26 * the whole document *
 [X]  - LANIER L L ET AL, "The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function", IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, (20001201), vol. 21, no. 12, ISSN 0167-5699, pages 611 - 614, XP004225437 [X] 1,2,4,9,10,14-17,26 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0167-5699(00)01745-X
 [A]  - WILSON MICHAEL J ET AL, "DAP12 and KAP10 (DAP10)-novel transmembrane adapter proteins of the CD3zeta family", IMMUNOLOGIC RESEARCH, (200008), vol. 22, no. 1, ISSN 0257-277X, pages 21 - 42, XP008031827 [A] 1-26 * the whole document *

DOI:   http://dx.doi.org/10.1385/IR:22:1:21
 [A]  - DIETRICH JES ET AL, "Human inhibitory and activating Ig-like receptors which modulate the function of myeloid cells", MICROBES AND INFECTION, (200003), vol. 2, no. 3, ISSN 1286-4579, pages 323 - 329, XP002285054 [A] 1-26 * the whole document *

DOI:   http://dx.doi.org/10.1016/S1286-4579(00)00294-X
 [T]  - BOUCHON A ET AL, "TREM-1 amplifies inflammation and is a crucial mediator of septic shock.", NATURE. 26 APR 2001, (20010426), vol. 410, no. 6832, ISSN 0028-0836, pages 1103 - 1107, XP002285055 [T] 1-26 * the whole document *

DOI:   http://dx.doi.org/10.1038/35074114
 [T]  - NOCHI HITOSHI ET AL, "Modulation of hepatic granulomatous responses by transgene expression of DAP12 or TREM-1-Ig molecules.", AMERICAN JOURNAL OF PATHOLOGY. APR 2003, (200304), vol. 162, no. 4, ISSN 0002-9440, pages 1191 - 1201, XP002285056 [T] 1-26 * the whole document *
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.