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Extract from the Register of European Patents

EP About this file: EP1262191

EP1262191 - Pharmaceutical compositions comprising recombinant human acid alpha-glucosidase containing mannose 6-phosphate [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  01.06.2007
Database last updated on 19.10.2024
Most recent event   Tooltip01.06.2007Withdrawal of applicationpublished on 04.07.2007  [2007/27]
Applicant(s)For all designated states
Pharming Intellectual Property BV
Archimedesweg 4
2333 CN Leiden / NL
For all designated states
Erasmus Universiteit Rotterdam
Burgemeester Oudlaan 50
3062 PA Rotterdam / NL
For all designated states
Academic Hospital Rotterdam
Dr Molewaterplein 60
3015 GJ Rotterdam / NL
[2003/10]
Former [2002/49]For all designated states
Pharming B.V.
Niels Bohrweg 11-13
2333 CA Leiden / NL
For all designated states
Erasmus Universiteit Rotterdam
Burgemeester Oudlaan 50
3062 PA Rotterdam / NL
For all designated states
Academic Hospital Rotterdam
Dr Molewaterplein 60
3015 GJ Rotterdam / NL
Inventor(s)01 / Reuser, Arnold, J.J.
Heemraadsingel 211A
3023 Rotterdam / NL
02 / Van der Ploeg, Ans, T.
Meidoorn 27
3171 NB Portugaal / NL
03 / Pieper, Frank, R.
Meindert Hobbemastraat 27
2102 BH Heemstede / NL
04 / Verbeet, Martin, Ph.
2e Oosterparkstraat 239
1092 BM Amsterdam / NL
 [2003/04]
Representative(s)Renes, Johan
V.O.
Johan de Wittlaan 7
2517 JR Den Haag / NL
[N/P]
Former [2004/25]Renes, Johan
Vereenigde Postbus 87930
2508 DH Den Haag / NL
Former [2003/04](deleted)
Former [2002/49]HOFFMANN - EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date02018187.131.07.1996
[2002/49]
Priority number, dateUS19950001796P02.08.1995         Original published format: US 1796 P
[2002/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1262191
Date:04.12.2002
Language:EN
[2002/49]
Search report(s)(Supplementary) European search report - dispatched on:EP14.10.2002
ClassificationIPC:A61K38/47, C12N15/56, C12N9/26, A61P21/00, // A01K67/027
[2002/49]
CPC:
C12N9/2408 (EP); A61P21/00 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2002/49]
TitleGerman:Pharmazeutische Zusammensetzungen mit rekombinanter humaner saurer Alpha-Glucosidase, die Mannose 6-Phosphate enthalten[2002/49]
English:Pharmaceutical compositions comprising recombinant human acid alpha-glucosidase containing mannose 6-phosphate[2002/49]
French:Compositions pharmaceutiques comprenant l' alpha-glucosidase acide humaine recombinante contenant du mannose 6-phosphate[2002/49]
Examination procedure04.06.2003Examination requested  [2004/25]
29.05.2007Application withdrawn by applicant  [2007/27]
Parent application(s)   TooltipEP96928405.8  / EP0845939
Fees paidRenewal fee
18.02.2003Renewal fee patent year 03
18.02.2003Renewal fee patent year 04
18.02.2003Renewal fee patent year 05
18.02.2003Renewal fee patent year 06
18.02.2003Renewal fee patent year 07
25.08.2003Renewal fee patent year 08
22.07.2004Renewal fee patent year 09
20.07.2005Renewal fee patent year 10
27.07.2006Renewal fee patent year 11
Penalty fee
Additional fee for renewal fee
19.08.200203   M06   Fee paid on   18.02.2003
19.08.200204   M06   Fee paid on   18.02.2003
19.08.200205   M06   Fee paid on   18.02.2003
19.08.200206   M06   Fee paid on   18.02.2003
19.08.200207   M06   Fee paid on   18.02.2003
31.07.200308   M06   Fee paid on   25.08.2003
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Documents cited:Search[DY]WO9325567  (GENPHARM INT [US], et al) [DY] 1-24*see the whole patent*;
 [PX]  - AGNES G.A. BIJVOET ET AL., "Expression of cDNA-encoded human acid alfa-glucosidase in milk of transgenic mice", BIOCHEMICA BIOPHYSICA ACTA, (1996), vol. 1308, pages 93 - 96, XP000609555 [PX] 1-4,6,8-14,16-23 *see the whole article*
 [PX]  - J.L.K. VAN HOVE ET AL., "High-level production of recombinant human lysosomal acid alpha-glucosidase in Chinese hamster ovary cells which targets to heart muscle and corrects glycogen accumulation in fibroblasts from patients with Pompe disease.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, WASHINGTON, US, (199601), vol. 93, no. 1, pages 65 - 70, XP002215266 [PX] 1-13,15-24 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.93.1.65
 [DX]  - A.T. VAN DER PLOEG ET AL., "Intravenous administration of phosphorylated acid alfa-glucosidase leads to uptake of enzyme in heart and skeletal muscle of mice", J. CLIN. INVEST., (1991), vol. 87, no. 2, pages 513 - 518, XP000609448 [DX] 1-4,6,8-13,16-23 *see the whole article*

DOI:   http://dx.doi.org/10.1172/JCI115025
 [XY]  - LIES H. HOEFSLOOT ET AL., "Expression and routeing of human lysosomal alfa-glucosidase in transiently transfected mammalian cells", BIOCHEMICAL JOURNAL, (1990), vol. 282, pages 485 - 492, XP000609457 [X] 1-4,6,8-13,16-23 *see the whole article* [Y] 1-24
 [Y]  - GERARD J. PLATENBURG ET AL., "Expression of human lactoferrin in milk of transgenic mice", TRANSGENIC RESEARCH, (1994), vol. 3, pages 99 - 108, XP000565362 [Y] 1-24 *see the whole article*

DOI:   http://dx.doi.org/10.1007/BF01974087
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