EP1262191 - Pharmaceutical compositions comprising recombinant human acid alpha-glucosidase containing mannose 6-phosphate [Right-click to bookmark this link] | Status | The application has been withdrawn Status updated on 01.06.2007 Database last updated on 19.10.2024 | Most recent event Tooltip | 01.06.2007 | Withdrawal of application | published on 04.07.2007 [2007/27] | Applicant(s) | For all designated states Pharming Intellectual Property BV Archimedesweg 4 2333 CN Leiden / NL | For all designated states Erasmus Universiteit Rotterdam Burgemeester Oudlaan 50 3062 PA Rotterdam / NL | For all designated states Academic Hospital Rotterdam Dr Molewaterplein 60 3015 GJ Rotterdam / NL | [2003/10] |
Former [2002/49] | For all designated states Pharming B.V. Niels Bohrweg 11-13 2333 CA Leiden / NL | ||
For all designated states Erasmus Universiteit Rotterdam Burgemeester Oudlaan 50 3062 PA Rotterdam / NL | |||
For all designated states Academic Hospital Rotterdam Dr Molewaterplein 60 3015 GJ Rotterdam / NL | Inventor(s) | 01 /
Reuser, Arnold, J.J. Heemraadsingel 211A 3023 Rotterdam / NL | 02 /
Van der Ploeg, Ans, T. Meidoorn 27 3171 NB Portugaal / NL | 03 /
Pieper, Frank, R. Meindert Hobbemastraat 27 2102 BH Heemstede / NL | 04 /
Verbeet, Martin, Ph. 2e Oosterparkstraat 239 1092 BM Amsterdam / NL | [2003/04] | Representative(s) | Renes, Johan V.O. Johan de Wittlaan 7 2517 JR Den Haag / NL | [N/P] |
Former [2004/25] | Renes, Johan Vereenigde Postbus 87930 2508 DH Den Haag / NL | ||
Former [2003/04] | (deleted) | ||
Former [2002/49] | HOFFMANN - EITLE Patent- und Rechtsanwälte Arabellastrasse 4 81925 München / DE | Application number, filing date | 02018187.1 | 31.07.1996 | [2002/49] | Priority number, date | US19950001796P | 02.08.1995 Original published format: US 1796 P | [2002/49] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP1262191 | Date: | 04.12.2002 | Language: | EN | [2002/49] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 14.10.2002 | Classification | IPC: | A61K38/47, C12N15/56, C12N9/26, A61P21/00, // A01K67/027 | [2002/49] | CPC: |
C12N9/2408 (EP);
A61P21/00 (EP)
| Designated contracting states | AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2002/49] | Title | German: | Pharmazeutische Zusammensetzungen mit rekombinanter humaner saurer Alpha-Glucosidase, die Mannose 6-Phosphate enthalten | [2002/49] | English: | Pharmaceutical compositions comprising recombinant human acid alpha-glucosidase containing mannose 6-phosphate | [2002/49] | French: | Compositions pharmaceutiques comprenant l' alpha-glucosidase acide humaine recombinante contenant du mannose 6-phosphate | [2002/49] | Examination procedure | 04.06.2003 | Examination requested [2004/25] | 29.05.2007 | Application withdrawn by applicant [2007/27] | Parent application(s) Tooltip | EP96928405.8 / EP0845939 | Fees paid | Renewal fee | 18.02.2003 | Renewal fee patent year 03 | 18.02.2003 | Renewal fee patent year 04 | 18.02.2003 | Renewal fee patent year 05 | 18.02.2003 | Renewal fee patent year 06 | 18.02.2003 | Renewal fee patent year 07 | 25.08.2003 | Renewal fee patent year 08 | 22.07.2004 | Renewal fee patent year 09 | 20.07.2005 | Renewal fee patent year 10 | 27.07.2006 | Renewal fee patent year 11 | Penalty fee | Additional fee for renewal fee | 19.08.2002 | 03   M06   Fee paid on   18.02.2003 | 19.08.2002 | 04   M06   Fee paid on   18.02.2003 | 19.08.2002 | 05   M06   Fee paid on   18.02.2003 | 19.08.2002 | 06   M06   Fee paid on   18.02.2003 | 19.08.2002 | 07   M06   Fee paid on   18.02.2003 | 31.07.2003 | 08   M06   Fee paid on   25.08.2003 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [DY]WO9325567 (GENPHARM INT [US], et al) [DY] 1-24*see the whole patent*; | [PX] - AGNES G.A. BIJVOET ET AL., "Expression of cDNA-encoded human acid alfa-glucosidase in milk of transgenic mice", BIOCHEMICA BIOPHYSICA ACTA, (1996), vol. 1308, pages 93 - 96, XP000609555 [PX] 1-4,6,8-14,16-23 *see the whole article* | [PX] - J.L.K. VAN HOVE ET AL., "High-level production of recombinant human lysosomal acid alpha-glucosidase in Chinese hamster ovary cells which targets to heart muscle and corrects glycogen accumulation in fibroblasts from patients with Pompe disease.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, WASHINGTON, US, (199601), vol. 93, no. 1, pages 65 - 70, XP002215266 [PX] 1-13,15-24 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.93.1.65 | [DX] - A.T. VAN DER PLOEG ET AL., "Intravenous administration of phosphorylated acid alfa-glucosidase leads to uptake of enzyme in heart and skeletal muscle of mice", J. CLIN. INVEST., (1991), vol. 87, no. 2, pages 513 - 518, XP000609448 [DX] 1-4,6,8-13,16-23 *see the whole article* DOI: http://dx.doi.org/10.1172/JCI115025 | [XY] - LIES H. HOEFSLOOT ET AL., "Expression and routeing of human lysosomal alfa-glucosidase in transiently transfected mammalian cells", BIOCHEMICAL JOURNAL, (1990), vol. 282, pages 485 - 492, XP000609457 [X] 1-4,6,8-13,16-23 *see the whole article* [Y] 1-24 | [Y] - GERARD J. PLATENBURG ET AL., "Expression of human lactoferrin in milk of transgenic mice", TRANSGENIC RESEARCH, (1994), vol. 3, pages 99 - 108, XP000565362 [Y] 1-24 *see the whole article* DOI: http://dx.doi.org/10.1007/BF01974087 |