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Extract from the Register of European Patents

EP About this file: EP1383499

EP1383499 - METHOD OF IMMUNOMODULATION USING THIONE-FORMING DISULFIDES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  10.01.2014
Database last updated on 25.09.2024
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR
published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
The GRASSETTI Family Trust
19810 Peppermint Falls Road
Jamestown, CA 95327 / US
[2006/07]
Former [2004/05]For all designated states
Grassetti, Davide R.
19810 Peppermint Falls Road
Jamestown, CA 95327 / US
Inventor(s)01 / GRASSETTI, Davide, R.
deceased / US
02 / MORO, Camillo
Via G. Zanon, 26
I-35133 Padova / IT
 [2006/07]
Former [2004/05]01 / GRASSETTI, Davide, R.
19810 Peppermint Falls Road
Jamestown, CA 95327 / US
02 / MORO, Camillo
Via G. Zanon, 26
I-35133 Padova / IT
Representative(s)Wibbelmann, Jobst, et al
Wuesthoff & Wuesthoff
Patentanwälte und Rechtsanwalt PartG mbB
Schweigerstrasse 2
81541 München / DE
[N/P]
Former [2013/10]Wibbelmann, Jobst, et al
Wuesthoff & Wuesthoff Patent- und Rechtsanwälte Schweigerstrasse 2
81541 München / DE
Former [2004/05]Wibbelmann, Jobst, Dr., Dipl.-Chem., et al
Wuesthoff & Wuesthoff, Patent- und Rechtsanwälte, Schweigerstrasse 2
81541 München / DE
Application number, filing date02705749.610.01.2002
[2004/05]
WO2002US00795
Priority number, dateUS20010260943P10.01.2001         Original published format: US 260943 P
[2004/05]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO02055080
Date:18.07.2002
Language:EN
[2002/29]
Type: A2 Application without search report 
No.:EP1383499
Date:28.01.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 18.07.2002 takes the place of the publication of the European patent application.
[2004/05]
Type: B1 Patent specification 
No.:EP1383499
Date:06.03.2013
Language:EN
[2013/10]
Search report(s)International search report - published on:EP04.12.2003
ClassificationIPC:A61K31/44, A61K31/505, A61K31/426, A61K31/10, A61P37/02
[2004/05]
CPC:
A61K31/426 (EP,US); A61K31/455 (EP,US); A61K31/505 (EP,US);
A61P31/12 (EP); A61P31/16 (EP); A61P31/18 (EP);
A61P37/02 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/05]
TitleGerman:VERFAHREN ZUR IMMUNOMODULIERUNG MIT THIONEBILDENDEN DISULFIDEN[2012/35]
English:METHOD OF IMMUNOMODULATION USING THIONE-FORMING DISULFIDES[2004/05]
French:METHODE D'MMUNOMODULATION AU MOYEN DE DISULFURES A FORMATION DE THIONE[2004/05]
Former [2004/05]VERFAHREN ZUR IMMUNOMODULIERUNG MIT THIONEBILDENDE DISULFIDE
Entry into regional phase01.07.2003National basic fee paid 
01.07.2003Designation fee(s) paid 
01.07.2003Examination fee paid 
Examination procedure01.07.2003Examination requested  [2004/05]
22.08.2006Despatch of a communication from the examining division (Time limit: M06)
28.02.2007Reply to a communication from the examining division
10.09.2007Despatch of a communication from the examining division (Time limit: M04)
03.01.2008Reply to a communication from the examining division
24.07.2008Despatch of a communication from the examining division (Time limit: M06)
27.01.2009Reply to a communication from the examining division
28.05.2009Despatch of a communication from the examining division (Time limit: M06)
30.11.2009Reply to a communication from the examining division
21.01.2010Despatch of a communication from the examining division (Time limit: M04)
19.05.2010Reply to a communication from the examining division
28.07.2010Despatch of a communication from the examining division (Time limit: M06)
03.02.2011Reply to a communication from the examining division
14.02.2011Despatch of a communication from the examining division (Time limit: M02)
20.04.2011Reply to a communication from the examining division
31.07.2012Communication of intention to grant the patent
28.11.2012Fee for grant paid
28.11.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.08.2006
Opposition(s)09.12.2013No opposition filed within time limit [2014/07]
Fees paidRenewal fee
19.01.2004Renewal fee patent year 03
20.01.2005Renewal fee patent year 04
19.01.2006Renewal fee patent year 05
17.01.2007Renewal fee patent year 06
17.01.2008Renewal fee patent year 07
19.01.2009Renewal fee patent year 08
19.01.2010Renewal fee patent year 09
19.01.2011Renewal fee patent year 10
31.01.2012Renewal fee patent year 11
17.01.2013Renewal fee patent year 12
Opt-out from the exclusive  Tooltip
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT06.03.2013
BE06.03.2013
CY06.03.2013
DK06.03.2013
FI06.03.2013
IT06.03.2013
MC06.03.2013
NL06.03.2013
SE06.03.2013
TR06.03.2013
GR07.06.2013
ES17.06.2013
PT08.07.2013
[2016/33]
Former [2014/38]AT06.03.2013
BE06.03.2013
CY06.03.2013
DK06.03.2013
FI06.03.2013
IT06.03.2013
MC06.03.2013
NL06.03.2013
SE06.03.2013
GR07.06.2013
ES17.06.2013
PT08.07.2013
Former [2014/11]AT06.03.2013
BE06.03.2013
CY06.03.2013
DK06.03.2013
FI06.03.2013
IT06.03.2013
NL06.03.2013
SE06.03.2013
GR07.06.2013
ES17.06.2013
PT08.07.2013
Former [2014/09]AT06.03.2013
BE06.03.2013
CY06.03.2013
DK06.03.2013
FI06.03.2013
NL06.03.2013
SE06.03.2013
GR07.06.2013
ES17.06.2013
PT08.07.2013
Former [2013/52]AT06.03.2013
BE06.03.2013
CY06.03.2013
FI06.03.2013
NL06.03.2013
SE06.03.2013
GR07.06.2013
ES17.06.2013
PT08.07.2013
Former [2013/48]AT06.03.2013
BE06.03.2013
FI06.03.2013
NL06.03.2013
SE06.03.2013
GR07.06.2013
ES17.06.2013
PT08.07.2013
Former [2013/47]AT06.03.2013
BE06.03.2013
FI06.03.2013
SE06.03.2013
GR07.06.2013
ES17.06.2013
PT08.07.2013
Former [2013/44]AT06.03.2013
BE06.03.2013
FI06.03.2013
SE06.03.2013
GR07.06.2013
ES17.06.2013
Former [2013/37]AT06.03.2013
FI06.03.2013
SE06.03.2013
GR07.06.2013
ES17.06.2013
Former [2013/36]AT06.03.2013
SE06.03.2013
ES17.06.2013
Former [2013/34]SE06.03.2013
Cited inInternational search[XA]EP0194571  (HOECHST AG [DE]) [X] 1-3,7,17-22,24 * page 2 - page 8, line 17 * * page 12 - page 16, line 13 * * page 19 - page 20, line 15 * * page 22 - page 23; example 8 * * claims 1-3,5 * [A] 10,12;
 [X]EP0236929  (MITSUI TOATSU CHEMICALS [JP]) [X] 1-3,7,9 * the whole document, especially pages 8-10 *;
 [X]WO9604242  (WARNER LAMBERT CO [US]) [X] 1,17-22 * page 2 lines 5-9, 18-20; page 6 lines 15-35; page 7 lines 1-8 * * page 96 - page 101 * * claims 78,79 *;
 [A]US5889050  (ANDERSSON CARL-MAGNUS ALEXANDE [SE], et al) [A] 1 * column 2 *;
 [A]WO9942097  (DOVETAIL TECHNOLOGIES INC [US], et al) [A] 1-6,10-16 * the whole document, especially page 5 *;
 [A]US6001555  (HENDERSON LOUIS E [US], et al) [A] 1-4,17-24 * column 3, line 11 - line 18 * * column 4, line 21 - line 25 * * column 8, line 8 - line 20 * * column 13, line 50 - line 67 *;
 JP2002193796  [ ] (AJINOMOTO KK) [ ] * Table 2, 6th compound; Table 4 second compound; Table 5 7th compound; Table 6 first, 6th and 7th compounds; Table 7 first and 5th compounds. *;
 [X]  - WHITEHOUSE M W ET AL, "CELL SURFACE POISONS (ZOG'S) AS POTENTIAL IMMUNOSUPPRESSIVE AGENTS", PHARMACOLOGIST, AMERICAN SOCIETY FOR PHARMACOLOGY AND EXPERIMENTAL THERAPEUTIC, US, (1971), vol. 13, no. 2, ISSN 0031-7004, page 236, XP008018260 [X] 1,2,17-23 * abstract 252 *
 [XA]  - MERRYMAN P F ET AL, "ALTERATION OF LYMPHOCYTE RESPONSE BY SULFHYDRYL AND DISULFIDE COMPOUNDS", BIOCHEMICAL PHARMACOLOGY, PERGAMON, OXFORD, GB, (19790701), vol. 28, no. 15, ISSN 0006-2952, pages 2297 - 2302, XP008018277 [X] 1-3,17-22 * page 2297, column L, paragraph 1 * * figure 2 * * page 2300 - page 2302 * [A] 10,11

DOI:   http://dx.doi.org/10.1016/0006-2952(79)90693-2
 [XA]  - SYLWESTER A W ET AL, "CD4+ T-LYMPHOCYTE DEPLETION IN HUMAN LYMPHOID TISSUE EX VIVO IS NOT INDUCED BY NONINFECTIOUS HUMAN IMMUNODEFICENCY VIRUS TYPE 1 VIRIONS", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (199811), vol. 72, no. 11, ISSN 0022-538X, pages 9345 - 9347, XP001148244 [X] 1,2,17-22 * the whole document * [A] 3,4
 [X]  - HADDEN J W, "THYMOMIMETIC DRUGS", SERONO SYMPOSIA SERIES, RAVEN PRESS, NEW YORK, NY, US, (1985), ISSN 1057-624X, pages 183 - 192, XP008018269 [X] 1,2,7 * page 187, paragraph 2 * * page 189; table 1 *
 [XA]  - IKARASHI Y ET AL, "EVALUATION OF CONTACT SENSITIVITY OF RUBBER CHEMICALS USING THE MURINE LOCAL LYMPH NODE ASSAY", CONTACT DERMATITIS, MUNKSGAARD, DK, (1993), vol. 28, no. 2, ISSN 0105-1873, pages 77 - 80, XP008018268 [X] 1,2 * the whole document * [A] 3
 [X]  - KORCHAK H M ET AL, "ACTIVATION OF THE NEUTROPHIL: THE ROLE OF ANION FLUXES IN NEUTROPHIL SECRETION", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, NEW YORK ACADEMY OF SCIENCES, NEW YORK, NY, US, (1980), ISSN 0077-8923, pages 346 - 347, XP008018274 [X] 1 * the whole document *

DOI:   http://dx.doi.org/10.1111/j.1749-6632.1980.tb15414.x
 [X]  - TOOHEY J I, "PERSULFIDE SULFUR IS A GROWTH FACTOR FOR CELLS DEFECTIVE IN SULFUR METABOLISM", BIOCHEMISTRY AND CELL BIOLOGY. BIOCHIMIE ET BIOLOGIE CELLULAIRE, XX, XX, (198608), vol. 64, no. 8, ISSN 0829-8211, pages 758 - 765, XP008018273 [X] 1,2 * the whole document *
 [A]  - DOMAGALA J M ET AL, "2,2'-DITHIOBISBENZAMIDES AND 2-BENZISOTHIAZOLONES, TWO NEW CLASSES OF ANTIRETROVIRAL AGENTS: SAR AND MECHANISTIC CONSIDERATIONS", DRUG DESIGN AND DISCOVERY, HARWOOD ACADEMIC PUBLISHERS GMBH, XX, (1997), vol. 15, no. 1, ISSN 1055-9612, pages 49 - 61, XP001036902 [A] 1,4,17-21 * the whole document *
 [E]  - DATABASE WPI, 1, Derwent World Patents Index, vol. 2002, no. 64, Database accession no. 2002-594385, XP002251717 [E] 1,17-24 * abstract *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.