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EP About this file: EP1373896

EP1373896 - CELL-BASED DETECTION AND DIFFERENTIATION OF DISEASE STATES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  02.07.2010
Database last updated on 03.09.2024
Most recent event   Tooltip02.07.2010Application deemed to be withdrawnpublished on 04.08.2010  [2010/31]
Applicant(s)For all designated states
MonoGen, Inc.
1033 Butterfield Road
Vernon Hills, IL 60061-1360 / US
[2004/01]
Inventor(s)01 / PRESSMAN, Norman, J.
390 Greenwood Avenue
Glencoe, IL 60022 / US
02 / HIRSCH, Kenneth, S.
Deceased
. / US
 [2004/06]
Former [2004/01]01 / PRESSMAN, Norman, J.
390 Greenwood Avenue
Glencoe, IL 60022 / US
02 / HIRSCH, Kenneth, S.
807 Portman Drive
Redwood City, CA 94065 / US
Representative(s)WP Thompson
8th Floor
1 Mann Island
Liverpool L3 1BP / GB
[N/P]
Former [2004/01]W.P. Thompson & Co.
Coopers Building, Church Street
Liverpool L1 3AB / GB
Application number, filing date02708460.712.03.2002
[2004/01]
WO2002GB01125
Priority number, dateUS20010274638P12.03.2001         Original published format: US 274638 P
[2004/01]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO02073204
Date:19.09.2002
Language:EN
[2002/38]
Type: A2 Application without search report 
No.:EP1373896
Date:02.01.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 19.09.2002 takes the place of the publication of the European patent application.
[2004/01]
Search report(s)International search report - published on:EP30.10.2003
ClassificationIPC:G01N33/569, G01N33/574
[2004/01]
CPC:
G01N33/57423 (EP,US); G01N33/569 (KR); G01N33/56966 (EP,US);
G01N33/57492 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/01]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:AUF ZELLEN BASIERTE NACHWEIS UND UNTERSCHEIDUNG VON KRANKHEITSZUSTÄNDEN[2004/01]
English:CELL-BASED DETECTION AND DIFFERENTIATION OF DISEASE STATES[2004/01]
French:DETECTION ET DIFFERENCIATION D'ETATS PATHOLOGIQUES PAR ECHANTILLONS CELLULAIRES[2004/01]
Entry into regional phase30.09.2003National basic fee paid 
30.09.2003Designation fee(s) paid 
30.09.2003Examination fee paid 
Examination procedure08.10.2002Request for preliminary examination filed
International Preliminary Examining Authority: EP
30.09.2003Amendment by applicant (claims and/or description)
30.09.2003Examination requested  [2004/01]
24.05.2006Despatch of a communication from the examining division (Time limit: M06)
22.12.2006Reply to a communication from the examining division
29.09.2009Despatch of a communication from the examining division (Time limit: M04)
10.02.2010Application deemed to be withdrawn, date of legal effect  [2010/31]
16.03.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2010/31]
Request for further processing for:22.12.2006Request for further processing filed
22.12.2006Full payment received (date of receipt of payment)
Request granted
10.01.2007Decision despatched
Fees paidRenewal fee
30.09.2003Renewal fee patent year 03
08.03.2005Renewal fee patent year 04
15.03.2006Renewal fee patent year 05
14.03.2007Renewal fee patent year 06
13.03.2008Renewal fee patent year 07
25.08.2009Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.03.200908   M06   Fee paid on   25.08.2009
31.03.201009   M06   Not yet paid
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Cited inInternational search[X]WO8706620  (MUREX CORP [US]) [X] 1,2,4-8,13 * the whole document *;
 [X]WO9424560  (INT MUREX TECH CORP [US], et al) [X] 1,2,4-8,14,21,23 * abstract, p. 22, lines 26 - 36, p. 27, lines 13 - 24, Examples, claims 1, 8, 9 *;
 [X]US5543291  (KEYOMARSI KHANDAN [US], et al) [X] 1-3,6-9,18,19,21-26,28,39 * column 4, line 12 - line 24; claims 38,39 *;
 [X]US5731162  (GATTI GUIDO [IT], et al) [X] 1,2,4-8,13 * the whole document *;
 [X]WO9828622  (FODSTAD OEYSTEIN [NO], et al) [X] 1-11,14-19,21-26,28-33,41,45-47 * p, 10 - 13, p. 15, lines 3 - 33, examples, Table 1, claims 1 - 12 *;
 [XY]US5997866  (JOHNSON KEITH R [US], et al) [X] 1-3,6-12,14,15,18,19,21-24,28,30,32,33 * Examples 1 - 3, claims 1 - 15 * [Y] 20;
 [PX]WO0136674  (ASTRAZENECA AB [SE], et al) [PX] 1-3,14,15,18,19,21,24-26,29-33 * p. 4, line 8 - p. 13, line 5, p. 20, lines 7 - 20, claims 1 - 9 *;
 [PX]WO0208764  (MEDICAL RES COUNCIL [GB], et al) [PX] 1-11,18,19,21-24,28,30,32,36-39,46,47 * claims 1, 2, 4, 6, 13, 15, 20 *;
 [X]  - LOZANO MARIA D ET AL, "Immunocytochemistry in the differential diagnosis of serous effusions: A comparative evaluation of eight monoclonal antibodies in Papanicolaou stained smears.", CANCER, (20010225), vol. 93, no. 1, ISSN 0008-543X, pages 68 - 72, XP009002477 [X] 1-3,5,12,14-19,21-24,30-33,37,38 * abstract, p. 69, col. 1, lines 14 - 22, tables 1 and 2, Discussion *

DOI:   http://dx.doi.org/10.1002/1097-0142(20010225)93:1<68::AID-CNCR9009>3.0.CO;2-F
 [Y]  - TOCKMAN M S ET AL, "SENSITIVE AND SPECIFIC MONOCLONAL ANTIBODY RECOGNITION OF HUMAN LUNG CANCER ANTIGEN ON PRESERVED SPUTUM CELLS: A NEW APPROACH TO EARLY LUNG CANCER DETECTION", JOURNAL OF CLINICAL ONCOLOGY, PHILADELPHIA, PA, US, (19881101), vol. 6, no. 11, pages 1685 - 1693, XP000614978 [Y] 20 * abstract *
 [X]  - FRISMAN DENNIS M ET AL, "Methods in pathology: Immunocytochemistry in the differential diagnosis of effusions: Use of logistic regression to select a panel of antibodies to distinguish adenocarcinomas from mesothelial proliferations.", MODERN PATHOLOGY, (1993), vol. 6, no. 2, ISSN 0893-3952, pages 179 - 184, XP009002474 [X] 1-3,5,12,14-19,21-24,30-33,37,38 * the whole document *
 [X]  - LEERS M P G ET AL, "E-cadherin and calretinin: A useful combination of immunochemical markers for differentiation between mesothelioma and metastatic adenocarcinoma.", HISTOPATHOLOGY (OXFORD), (199803), vol. 32, no. 3, ISSN 0309-0167, pages 209 - 216, XP002224146 [X] 1-3,5,14-19,21-24,28,30-33,36-38 * abstract, Materials and Methods, Discussion *

DOI:   http://dx.doi.org/10.1046/j.1365-2559.1998.00349.x
 [XY]  - SKOV B G ET AL, "Differentiation of adenocarcinoma of the lung and malignant mesothelioma: Predictive value and reproducibility of immunoreactive antibodies.", HISTOPATHOLOGY (OXFORD), (1994), vol. 25, no. 5, ISSN 0309-0167, pages 431 - 437, XP009002475 [X] 1-3,5,14-19,21-24,30-33,37,38 * the whole document * [Y] 20

DOI:   http://dx.doi.org/10.1111/j.1365-2559.1994.tb00004.x
 [Y]  - NEFT R E ET AL, "CONCURRENT FLUORESCENCE IN SITU HYBRIDIZATION AND IMMUNOCYTOCHEMISTRY FOR THE DETECTION OF CHROMOSOME ABERRATIONS IN EXFOLIATED BRONCHIAL EPITHELIAL CELLS", ACTA CYTOLOGICA, INTERNATIONAL ACADEMY OF CYTOLOGY, CHICAGO, IL,, US, (1997), vol. 41, no. 6, ISSN 0001-5547, pages 1769 - 1773, XP000961317 [Y] 20 * abstract *
 [PX]  - GONZALEZ-LOIS C ET AL, "Combined use of novel epithelial (MOC-31) and mesothelial (HBME-1) immunohistochemical markers for optimal first line diagnostic distinction between mesothelioma and metastatic carcinoma in pleura.", HISTOPATHOLOGY (OXFORD), (200106), vol. 38, no. 6, ISSN 0309-0167, pages 528 - 534, XP002224147 [PX] 1-3,12,14-19,21-24 * the whole document *

DOI:   http://dx.doi.org/10.1046/j.1365-2559.2001.01157.x
 [X]  - KALLAKURY BHASKAR V S ET AL, "The prognostic significance of proliferation-associated nucleolar protein p120 expression in prostate adenocarcinoma: A comparison with cyclins A and B1, Ki-67, proliferating cell nuclear antigen, and p34cdc2.", CANCER, (19990401), vol. 85, no. 7, ISSN 0008-543X, pages 1569 - 1576, XP002235530 [X] 1-3,6-11,18,19,21-26,28,30,32,36,37,39,45 * abstract, p. 1573, col. 1, line 3 - col. 2, line 16, *

DOI:   http://dx.doi.org/10.1002/(SICI)1097-0142(19990401)85:7<1569::AID-CNCR19>3.0.CO;2-M
 [X]  - VOLM M ET AL, "Prognostic value of ERBB-1, vEGF, cyclin A, FOS, JUN and MYC in patients with squamous cell lung carcinomas.", BRITISH JOURNAL OF CANCER, (199802), vol. 77, no. 4, ISSN 0007-0920, pages 663 - 669, XP009007843 [X] 1-3,6-12,14-19,21-24,28-33,36-39,45 * abstract, p. 664, col. 1, line 8 - p. 666 end of col. 1, Tables 3, 4, 6, p. 668, col. 2, final paragraph *
 [X]  - DESSY E ET AL, "[Surfactant protein and thyroid transcription factor 1 in pleuro-pulmonary neoplasia. Immunohistochemical study]", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (200012), Database accession no. NLM11234300, XP002235534 [X] 1-3,6-9,12,14-19,21-24,28,30,32,33,36-38,41,42 * abstract *
    [ ] - PATHOLOGICA. ITALY DEC 2000, (200012), vol. 92, no. 6, ISSN 0031-2983, pages 496 - 502
 [X]  - BEJARANO PABLO A ET AL, "Surfactant proteins and thyroid transcription factor-1 in pulmonary and breast carcinomas.", MODERN PATHOLOGY, (1996), vol. 9, no. 4, ISSN 0893-3952, pages 445 - 452, XP009007792 [X] 1-3,6-12,14-19,21-24,28,30,32,33,36-38,41,42 * the whole document *
 [PX]  - MITAS MICHAEL ET AL, "Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel.", INTERNATIONAL JOURNAL OF CANCER, (2001), vol. 93, no. 2, ISSN 0020-7136, pages 162 - 171, XP002235531 [PX] 1-3,6,8,9,18,19,21-26,28,31,36,37,41,42,45 * the whole document *

DOI:   http://dx.doi.org/10.1002/ijc.1312
 [X]  - GASPAR ROCIO HERNANDEZ ET AL, "Quantitative immunohistochemical analyses of the expression of E-cadherin, thrombomodulin, CD44H and CD44v6 in primary tumours of pharynx/larynx squamous cell carcinoma and their lymph node metastases.", ANALYTICAL CELLULAR PATHOLOGY, (1999), vol. 18, no. 4, ISSN 0921-8912, pages 183 - 190, XP009007804 [X] 1-3,6-11,14-17,21-24,28,43,44 * abstract, p. 184, col. 2, lines 1 - 32 *
 [X]  - FUKUSE TATSUO ET AL, "Expression of proliferating cell nuclear antigen and CD44 variant isoforms in the primary and metastatic sites of nonsmall cell lung carcinoma with intrapulmonary metastases.", CANCER, (19991001), vol. 86, no. 7, ISSN 0008-543X, pages 1174 - 1181, XP002235532 [X] 1-3,6-12,18,19,21,24,28,30,32,33,36,37,43,46,47 * abstract, introduction, Fig. 2 and 3, p. 1180, col. 2, lines 4 - 12 *

DOI:   http://dx.doi.org/10.1002/(SICI)1097-0142(19991001)86:7<1174::AID-CNCR11>3.0.CO;2-8
 [X]  - AKSLEN LARS A ET AL, "Oncoproteins and tumor progression in papillary thyroid carcinoma: Presence of epidermal growth factor receptor, c-erbB-2 protein, estrogen receptor related protein, p21-ras protein, and proliferation indicators in relation to tumor recurrences and patient survival.", CANCER (PHILADELPHIA), (1995), vol. 76, no. 9, ISSN 0008-543X, pages 1643 - 1654, XP009007851 [X] 1-3,6-9,18,19,21-26,28,29,31-34,36,37,43,47 * abstr, p. 1644, col. 2, 2nd paragraph, p. 1649, col. 1, lines 5 - 17 *
 [X]  - REIS-FILHO JORGE S ET AL, "Evaluation of cell proliferation, epidermal growth factor receptor, and bcl-2 immunoexpression as prognostic factors for patients with World Health Organization Grade 2 oligodendroglioma.", CANCER., vol. 88, no. 4, ISSN 0008-543X, pages 862 - 869, XP002235533 [X] 1-3,6-11,18,19,21-23,28,32,36,37,46,47 * abstract, Table 3 *

DOI:   http://dx.doi.org/10.1002/(SICI)1097-0142(20000215)88:4<862::AID-CNCR17>3.0.CO;2-G
 [X]  - PASTORINO UGO ET AL, "Immunocytochemical markers in stage I lung cancer: Relevance to prognosis.", JOURNAL OF CLINICAL ONCOLOGY, (1997), vol. 15, no. 8, ISSN 0732-183X, pages 2858 - 2865, XP009007844 [X] 1-3,6-12,18,19,21-24,28-30,32,33,37,38,47 * abstract, p. 2859, col. 2, 2nd paragraph, Table 4, p. 2863, col. 1, lines 12 - 30 *
 [X]  - ORCHARD G E ET AL, "Immunocytochemistry in the diagnosis of Kaposi's sarcoma and angiosarcoma.", BRITISH JOURNAL OF BIOMEDICAL SCIENCE. ENGLAND MAR 1995, (199503), vol. 52, no. 1, ISSN 0967-4845, pages 35 - 49, XP009007990 [X] 1-3,6-11,18,19,21-23,25,26 * p. 37, col. 1, last paragraph *
 [X]  - PIATTI B ET AL, "Fine needle aspiration biopsy of hepatocellular carcinoma resembling neuroendocrine tumor. A case report.", ACTA CYTOLOGICA. UNITED STATES 1997 MAR-APR, (199703), vol. 41, no. 2, ISSN 0001-5547, pages 583 - 586, XP009007979 [X] 1-3,6-11,18,19,21-26 * abstract, p. 584, col. 2, lines 26 - 33, p. 585, col. 2, lines 12 - 20 *
 [X]  - LUCAS D R ET AL, "Ewing sarcoma vs lymphoblastic lymphoma. A comparative immunohistochemical study.", AMERICAN JOURNAL OF CLINICAL PATHOLOGY. UNITED STATES JAN 2001, (200101), vol. 115, no. 1, ISSN 0002-9173, pages 11 - 17, XP009007975 [X] 1-3,6-11,14,15,18,19,21-27 * the whole document *

DOI:   http://dx.doi.org/10.1309/K1XJ-6CXR-BQQU-V255
 [X]  - CAMPANA D ET AL, "Immunophenotyping of leukemia.", JOURNAL OF IMMUNOLOGICAL METHODS. NETHERLANDS 2000 SEP 21, (20000921), vol. 243, no. 1-2, ISSN 0022-1759, pages 59 - 75, XP004210693 [X] 1-3,6-9,18,19,21-23,27 * abstract, tables 2,3,4 * * page 3 *

DOI:   http://dx.doi.org/10.1016/S0022-1759(00)00228-3
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