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Extract from the Register of European Patents

EP About this file: EP1490078

EP1490078 - HEPATOCURATIVE EFFECT OF EMBLICA OFFICINALIS ON HEPATOTOXICITY RELATED TO CYTOCHROME P-450 [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 23.11.2012 Database last updated on 20.07.2024
Most recent event Tooltip	23.11.2012	Application deemed to be withdrawn	published on 26.12.2012 [2012/52]
Applicant(s)	For all designated states Council of Scientific and Industrial Research Rafi Marg New Delhi 110 001 / IN
	[N/P]
Former [2005/01]	For all designated states Council of Scientific and Industrial Research Rafi Marg New Delhi 110 001 / IN
Inventor(s)	01 / Johri, Rakesh Kamal Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	02 / Abdullah, Sheikh Tasaduq Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	03 / Singh, Kuldeep Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	04 / Gupta, Devinder Kumar Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	05 / Kapahi, Bal Krishan Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	06 / Mondhe, Dilip Manikrao Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	07 / Jain, Satinder Mohan Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	08 / Suri, Om Parkash Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	09 / Bedi, Kasturi Lal Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	10 / Qazi, Ghulam Nabi Regional Research Laboratory Jammu, Canal Road Jammu 180 001 / IN
	[2005/01]
Representative(s)	Portal, Gérard, et al Cabinet Beau de Loménie 158, rue de l'Université 75340 Paris Cedex 07 / FR
	[N/P]
Former [2005/01]	Portal, Gérard, et al Cabinet Beau de Loménie 158, rue de l'Université 75340 Paris Cédex 07 / FR
Application number, filing date	02716955.6	26.03.2002
	[2005/01]
	WO2002IB00635
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO03080090
	Date:	02.10.2003
	Language:	EN
	[2003/40]
	Type:	A1 Application with search report
	No.:	EP1490078
	Date:	29.12.2004
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 02.10.2003 takes the place of the publication of the European patent application.
	[2004/53]
Search report(s)	International search report - published on:	EP	02.10.2003
Classification	IPC:	A61K35/78	[2005/01]
	CPC:	A61K36/47 (EP,KR); A61P1/16 (EP); A61P39/02 (EP); A61P43/00 (EP)
	C-Set:	A61K36/47, A61K2300/00 (EP)
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2005/01]
Extension states	AL	Not yet paid
	LT	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	RO	Not yet paid
	SI	Not yet paid
Title	German:	LEBERHEILENDE WIRKUNG VON EMBLICA OFFICINALIS AUF MIT ZYTOCHROM P-450 ZUSAMMENHÄNGENDE LEBERTOXIZITÄT	[2005/01]
	English:	HEPATOCURATIVE EFFECT OF EMBLICA OFFICINALIS ON HEPATOTOXICITY RELATED TO CYTOCHROME P-450	[2005/01]
	French:	EFFET HEPATOCURATIF D'EMBLICA OFFICINALIS SUR L'HEPATOTOXICITE ASSOCIEE AU CYTOCHROME P-450	[2005/01]
Entry into regional phase	21.10.2004	National basic fee paid
	21.10.2004	Designation fee(s) paid
	21.10.2004	Examination fee paid
Examination procedure	17.10.2003	Request for preliminary examination filed International Preliminary Examining Authority: EP
	22.10.2004	Amendment by applicant (claims and/or description)
	22.10.2004	Examination requested [2004/53]
	10.03.2005	Despatch of a communication from the examining division (Time limit: M06)
	12.09.2005	Reply to a communication from the examining division
	17.10.2005	Despatch of a communication from the examining division (Time limit: M06)
	19.04.2006	Reply to a communication from the examining division
	23.10.2007	Despatch of communication that the application is refused, reason: substantive examination {1}
	20.07.2012	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2012/52]
	02.10.2012	Application deemed to be withdrawn, date of legal effect [2012/52]
Appeal following examination	21.12.2007	Appeal received No. T0844/08
	22.02.2008	Statement of grounds filed
	01.10.2012	Result of appeal procedure: the application was deemed to be withdrawn
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 10.03.2005
Fees paid	Renewal fee
	21.10.2004	Renewal fee patent year 03
	28.12.2004	Renewal fee patent year 04
	06.01.2006	Renewal fee patent year 05
	29.12.2006	Renewal fee patent year 06
	27.12.2007	Renewal fee patent year 07
	29.12.2008	Renewal fee patent year 08
	Penalty fee
	Additional fee for renewal fee
	31.03.2010	09 M06 Not yet paid
	31.03.2011	10 M06 Not yet paid
	31.03.2012	11 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[X] - HAQUE R ET AL, "Protective effects of Emblica officinalis Gaertn. in cyclophosphamide-treated mice.", HUMAN & EXPERIMENTAL TOXICOLOGY, (200112), vol. 20, no. 12, ISSN 0960-3271, pages 643 - 650, XP008005023 [X] 1-7,11-13,15,18,20,21,26-29,36-38 * Abstract * * page 648, column R * * page 649, column L * DOI: http://dx.doi.org/10.1191/096032701718890568
		[X] - UDUPA VENKATESHA ET AL, "Effect of HD-03 on levels of various enzymes in paracetamol-induced liver damage in rats.", INDIAN JOURNAL OF PHARMACOLOGY, (200012), vol. 32, no. 6, ISSN 0253-7613, pages 361 - 364, XP008005025 [X] 1-6,11-13,15,18,20-22,24,26-30,36,38 * page 363, Discussion *
		[X] - SHARMA NIDHI ET AL, "In vitro inhibition of carcinogen-induced mutagenicity by Cassia occidentalis and Emblica officinalis.", DRUG AND CHEMICAL TOXICOLOGY AN INTERNATIONAL JOURNAL FOR RAPID, August, 2000, (200008), vol. 23, no. 3, ISSN 0148-0545, pages 477 - 484, XP008005026 [X] 1-7,11-13,15,20,21,26-28 * Abstract * * page 481 - 482, Discussion * DOI: http://dx.doi.org/10.1081/DCT-100100129
		[X] - SHARMA N ET AL, "Inhibitory effect of Emblica officinalis on the in vivo clastogenicity of benzo(a)pyrene and cyclophosphamide in mice.", HUMAN & EXPERIMENTAL TOXICOLOGY, (200006), vol. 19, no. 6, ISSN 0960-3271, pages 377 - 384, XP008005045 [X] 1-6,11-15,18-21,24,26-29,36-38 * page 382, Discussion * DOI: http://dx.doi.org/10.1191/096032700678815945
		[X] - JOSE JEENA K ET AL, "Hepatoprotective activity of Emblica officinalis and Chyavanaprash.", JOURNAL OF ETHNOPHARMACOLOGY, (200009), vol. 72, no. 1-2, ISSN 0378-8741, pages 135 - 140, XP002203394 [X] 1-6,15,18,20-22,24,26-28,32,36,38 * Abstract * * Materials and Methods * * page 139, Discussion (last paragraph) * DOI: http://dx.doi.org/10.1016/S0378-8741(00)00219-1
		[X] - JEENA K JOSE ET AL, "Effect of Emblica officinalis, Phyllanthus amarus and Picrorrhiza kurroa on N-nitrosodiethylamine induced hepatocarcinogenesis.", CANCER LETTERS, (19990206), vol. 136, no. 1, ISSN 0304-3835, pages 11 - 16, XP002203395 [X] 1-6,15,18,20,21,24,26-28,32,36-38 * Abstract * * page 12, paragraphs 2.1 and 2.5 * * page 15, column L * DOI: http://dx.doi.org/10.1016/S0304-3835(98)00294-8
	Examination	JPH1028549
		- DATABASE WPI, 1, Derwent World Patents Index, vol. 1998, no. 15, Database accession no. 1998-162497, & JPH1028549 A 19980203 (INAHATA KORYO KK)
		- DOTY S.L. ET AL, "Enhanced metabolism of halogenated hydrocarbons in transgenic plants containing mammalian cytochrome P450 2E1", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (2000), vol. 97, no. 12, pages 6287 - 6291
		- YAMAZAKI H. ET AL, "Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylamine to products genotoxic in an acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009)", CARCINOGENESIS, (1992), vol. 13, no. 6, pages 979 - 985, XP009089415

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