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Extract from the Register of European Patents

EP About this file: EP1461425

EP1461425 - NOVEL HUMAN HYDROXYLASES AND POLYNUCLEOTIDES ENCODING THE SAME [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  11.04.2014
Database last updated on 29.03.2025
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): CH, LI		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Lexicon Pharmaceuticals, Inc.
8800 Technology Forest Place
The Woodlands, TX 77381 / US
[2008/07]
Former [2007/28]For all designated states
Lexicon Pharmaceuticals, Inc.
8800 Technology Forest Place
The Woodlands TX 77381 / US
Former [2004/40]For all designated states
Lexicon Genetics Incorporated
8800 Technology Forest Place
The Woodlands, TX 77381-1160 / US
Inventor(s)01 / YU, Xuanchuan
6 Danville Crossing
Conroe, TX 77385 / US
02 / MIRANDA, Maricar
14814 Belterraza Drive
Houston, TX 77083 / US
03 / HU, Yi
25806 Elmley Place
Spring, TX 77389 / US
 [2007/27]
Former [2004/40]01 / YU, Xuanchuan
6 Danville Crossing
Conroe, TX 77385 / US
02 / MIRANDA, Maricar
14814 Belterraza Drive
Houston, TX 77083 / US
03 / HU, Yi
333 Holly Creek Ct. 203
The Woodlands, TX 77381 / US
Representative(s)Hewson, Timothy John, et al
Abel & Imray
20 Red Lion Street
London WC1R 4PQ / GB
[N/P]
Former [2013/27]Hewson, Timothy John, et al
Abel & Imray 20 Red Lion Street
London, WC1R 4PQ / GB
Former [2004/40]Silveston, Judith, et al
ABEL & IMRAY 20 Red Lion Street
London, WC1R 4PQ / GB
Application number, filing date02731941.723.05.2002
[2004/40]
WO2002US16635
Priority number, dateUS20010294076P29.05.2001         Original published format: US 294076 P
[2004/40]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO02097039
Date:05.12.2002
Language:EN
[2002/49]
Type: A2 Application without search report 
No.:EP1461425
Date:29.09.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 05.12.2002 takes the place of the publication of the European patent application.
[2004/40]
Type: B1 Patent specification 
No.:EP1461425
Date:13.02.2008
Language:EN
[2008/07]
Search report(s)International search report - published on:US08.07.2004
(Supplementary) European search report - dispatched on:EP04.11.2004
ClassificationIPC:C12N9/02, C12N15/53
[2004/40]
CPC:
C12N9/0004 (EP,US); A01K2217/05 (EP,US); C07K2319/00 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/40]
TitleGerman:NEUE MENSCHLICHE HYDROXYLASEN UND DIESE CODIERENDE POLYNUKLEOTIDE[2004/40]
English:NOVEL HUMAN HYDROXYLASES AND POLYNUCLEOTIDES ENCODING THE SAME[2004/40]
French:NOUVELLES HYDROXYLASES HUMAINES ET POLYNUCLEOTIDES CODANT CELLES-CI[2004/40]
Entry into regional phase18.11.2003National basic fee paid 
18.11.2003Search fee paid 
18.11.2003Designation fee(s) paid 
18.11.2003Examination fee paid 
Examination procedure03.12.2002Request for preliminary examination filed
International Preliminary Examining Authority: US
18.11.2003Examination requested  [2004/40]
18.11.2004Despatch of a communication from the examining division (Time limit: M06)
01.07.2005Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
12.09.2005Reply to a communication from the examining division
27.06.2006Despatch of a communication from the examining division (Time limit: M04)
27.10.2006Reply to a communication from the examining division
07.02.2007Communication of intention to grant the patent
22.05.2007Fee for grant paid
22.05.2007Fee for publishing/printing paid
26.07.2007Despatch of a communication from the examining division (Time limit: M02)
12.09.2007Reply to a communication from the examining division
Opposition(s)Opponent(s)01  12.11.2008    ADMISSIBLE
Max-Delbrück-Centrum für Molekulare Medizin (MDC) Berlin-Buch
Berlin-Buch
Robert-Rössle-Strasse 10
13092 Berlin / DE
Opponents representative
Krauss, Jan
Boehmert & Boehmert
Anwaltspartnerschaft mbB
Pettenkoferstrasse 22
80336 München / DE
 [N/P]
Former [2008/52]
Opponent(s)01  12.11.2008    ADMISSIBLE
Max-Delbrück-Centrum für Molekulare Medizin (MDC)
Berlin-Buch, Robert-Rössle-Strasse 10
13092 Berlin / DE
Opponents representative
Krauss, Jan
Forrester & Boehmert Pettenkoferstrasse 20-22
80336 München / DE
deletedDeletion: Legal effect of rejection of opposition [ N /P ]
18.12.2008Invitation to proprietor to file observations on the notice of opposition
24.06.2009Reply of patent proprietor to notice(s) of opposition
10.02.2010Date of oral proceedings
18.03.2010Despatch of minutes of oral proceedings
18.03.2010Date of despatch of rejection of opposition
13.03.2014Legal effect of revocation of patent [ N /P ]
13.03.2014Legal effect of revocation of patent [2014/20]
13.03.2014Despatch of communication that the patent will be revoked
Appeal following opposition18.05.2010Appeal received No.  T1109/10
23.07.2010Statement of grounds filed
13.03.2014Result of appeal procedure: revocation of the patent
13.03.2014Date of oral proceedings
18.03.2014Minutes of the oral proceedings despatched
Request for further processing for:12.09.2005Request for further processing filed
12.09.2005Full payment received (date of receipt of payment)
Request granted
28.09.2005Decision despatched
Fees paidRenewal fee
13.05.2004Renewal fee patent year 03
12.05.2005Renewal fee patent year 04
23.03.2006Renewal fee patent year 05
14.05.2007Renewal fee patent year 06
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT13.02.2008
CH13.02.2008
CY13.02.2008
DK13.02.2008
FI13.02.2008
IT13.02.2008
LI13.02.2008
TR13.02.2008
GR14.05.2008
LU23.05.2008
ES24.05.2008
MC31.05.2008
PT14.07.2008
[2014/34]
Former [2010/47]AT13.02.2008
CY13.02.2008
DK13.02.2008
FI13.02.2008
IT13.02.2008
TR13.02.2008
GR14.05.2008
LU23.05.2008
ES24.05.2008
MC31.05.2008
PT14.07.2008
Former [2010/37]AT13.02.2008
CY13.02.2008
DK13.02.2008
FI13.02.2008
IT13.02.2008
TR13.02.2008
LU23.05.2008
ES24.05.2008
MC31.05.2008
PT14.07.2008
Former [2010/32]AT13.02.2008
CY13.02.2008
DK13.02.2008
FI13.02.2008
IT13.02.2008
LU23.05.2008
ES24.05.2008
MC31.05.2008
PT14.07.2008
Former [2009/39]AT13.02.2008
CY13.02.2008
DK13.02.2008
FI13.02.2008
IT13.02.2008
ES24.05.2008
MC31.05.2008
PT14.07.2008
Former [2009/33]AT13.02.2008
CY13.02.2008
DK13.02.2008
FI13.02.2008
ES24.05.2008
MC31.05.2008
PT14.07.2008
Former [2009/04]AT13.02.2008
DK13.02.2008
FI13.02.2008
ES24.05.2008
MC31.05.2008
PT14.07.2008
Former [2008/49]AT13.02.2008
DK13.02.2008
FI13.02.2008
ES24.05.2008
PT14.07.2008
Former [2008/46]AT13.02.2008
DK13.02.2008
FI13.02.2008
ES24.05.2008
Former [2008/39]AT13.02.2008
FI13.02.2008
ES24.05.2008
Former [2008/35]ES24.05.2008
Documents cited:Search[X]  - EMBL, (19900725), Database accession no. X52836, XP002301931 [X] 10 * the whole document *
 [X]  - UNIPROT, (19901016), Database accession no. P17752, XP002301932 [X] 10 * the whole document *
International search[A]  - GREEN C B AND BESHARSE J C, "Tryptophan hydroxylase expression is regulated by a circadian clock in xenopus laevis retina", J. NEURO., (1994), vol. 62, pages 2420 - 2428, XP002976710
 [A]  - GRENETT H E ET AL, "Full-length cDNA for rabbit tryptophan hydroxylase: Functional domains and evolution of aromatic amino acid hydoxylases", PROC. NATL. ACAD. SCI., USA, (198708), vol. 84, pages 5530 - 5534, XP002976711

DOI:   http://dx.doi.org/10.1073/pnas.84.16.5530
 [A]  - ROBSON K J H ET AL, "Polysome immunoprecipitation of phenylalanine hydroxylase mRNA from rat liver and cloning of its cDNA", PROC. NATL. ACAD. SCI., USA, (198208), vol. 79, pages 4701 - 4705, XP002976712

DOI:   http://dx.doi.org/10.1073/pnas.79.15.4701
 [A]  - GRIMA B ET AL., "Complete coding sequence of rat tyrosine hydroxylase mRNA", PROC. NATL. ACAD. SCI., USA, (198501), vol. 82, pages 617 - 621, XP002976713

DOI:   http://dx.doi.org/10.1073/pnas.82.2.617
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.