blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP1368027

EP1368027 - USE OF TRYPTOPHAN DERIVATIVES FOR THE SPECIFIC CYTOSTATIC TREATMENT OF SEROTONIN-PRODUCING TUMORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  10.06.2005
Database last updated on 26.06.2024
Most recent event   Tooltip21.12.2007Lapse of the patent in a contracting state
New state(s): PT		published on 23.01.2008  [2008/04]
Applicant(s)For all designated states
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN
Robert-Rössle-Strasse 10
13125 Berlin / DE
[2003/50]
Inventor(s)01 / WALTHER, Diego
Florapromenade 28
13187 Berlin / DE
02 / BADER, Michael
Strasse 45, Nr. 35
13125 Berlin / DE
 [2004/09]
Former [2003/50]01 / WALTHER, Diego
Florastrasse 2
13187 Berlin / DE
02 / BADER, Michael
Strasse 45, Nr. 35
13125 Berlin / DE
Representative(s)Krauss, Jan
Boehmert & Boehmert
Anwaltspartnerschaft mbB
Pettenkoferstrasse 22
80336 München / DE
[N/P]
Former [2003/50]Krauss, Jan
Forrester & Boehmert, Pettenkoferstrasse 20-22
80336 München / DE
Application number, filing date02732330.215.03.2002
[2003/50]
WO2002DE00959
Priority number, dateDE200111288215.03.2001         Original published format: DE 10112882
[2003/50]
Filing languageDE
Procedural languageDE
PublicationType: A2 Application without search report
No.:WO02074309
Date:26.09.2002
Language:DE
[2002/39]
Type: A2 Application without search report 
No.:EP1368027
Date:10.12.2003
Language:DE
The application published by WIPO in one of the EPO official languages on 26.09.2002 takes the place of the publication of the European patent application.
[2003/50]
Type: B1 Patent specification 
No.:EP1368027
Date:04.08.2004
Language:DE
[2004/32]
Search report(s)International search report - published on:EP21.11.2002
ClassificationIPC:A61K31/405, A61P35/00
[2004/12]
CPC:
A61K31/405 (EP,US); A61P1/00 (EP); A61P1/18 (EP);
A61P11/00 (EP); A61P35/00 (EP); A61P35/04 (EP)
Former IPC [2003/50]A61K31/405
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/50]
TitleGerman:VERWENDUNG VON TRYPTOPHAN-DERIVATEN ZUR SPEZIFISCHEN ZYTOSTATISCHEN BEHANDLUNG VON SEROTONIN-PRODUZIERENDEN TUMOREN[2003/50]
English:USE OF TRYPTOPHAN DERIVATIVES FOR THE SPECIFIC CYTOSTATIC TREATMENT OF SEROTONIN-PRODUCING TUMORS[2003/50]
French:UTILISATION DE DERIVES DU TRYPTOPHANE POUR LE TRAITEMENT CYTOSTATIQUE SPECIFIQUE DE TUMEURS PRODUISANT DE LA SEROTONINE[2003/50]
Entry into regional phase19.08.2003National basic fee paid 
19.08.2003Designation fee(s) paid 
19.08.2003Examination fee paid 
Examination procedure15.10.2002Request for preliminary examination filed
International Preliminary Examining Authority: EP
19.08.2003Examination requested  [2003/50]
05.02.2004Communication of intention to grant the patent
11.05.2004Fee for grant paid
11.05.2004Fee for publishing/printing paid
Opposition(s)06.05.2005No opposition filed within time limit [2005/30]
Fees paidRenewal fee
19.08.2003Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipFI04.08.2004
IE04.08.2004
NL04.08.2004
TR04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
PT04.01.2005
CY15.03.2005
LU15.03.2005
BE31.03.2005
MC31.03.2005
[2008/04]
Former [2007/26]FI04.08.2004
IE04.08.2004
NL04.08.2004
TR04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
CY15.03.2005
LU15.03.2005
BE31.03.2005
MC31.03.2005
Former [2007/20]FI04.08.2004
IE04.08.2004
NL04.08.2004
TR04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
CY15.03.2005
BE31.03.2005
LU31.03.2005
MC31.03.2005
Former [2007/11]FI04.08.2004
IE04.08.2004
NL04.08.2004
TR04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
BE31.03.2005
LU31.03.2005
MC31.03.2005
Former [2006/52]FI04.08.2004
IE04.08.2004
NL04.08.2004
TR04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
BE31.03.2005
MC31.03.2005
Former [2006/23]FI04.08.2004
IE04.08.2004
NL04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
BE31.03.2005
MC31.03.2005
Former [2006/14]FI04.08.2004
IE04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
BE31.03.2005
MC31.03.2005
Former [2006/13]FI04.08.2004
IE04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
BE31.03.2005
Former [2005/24]FI04.08.2004
IE04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
Former [2005/22]FI04.08.2004
DK04.11.2004
GR04.11.2004
SE04.11.2004
Former [2005/18]FI04.08.2004
GR04.11.2004
SE04.11.2004
Former [2005/11]FI04.08.2004
SE04.11.2004
Former [2005/10]SE04.11.2004
Cited inInternational search[X]DE2236876  (AJINOMOTO KK) [X] 7 * page 19; example 25 *;
 [X]US4183858  (JUNG MICHEL [FR], et al) [X] 1,2,5,7,8 * column 3, line 47 - line 49 * * column 7, line 17 - line 27 * * column 8, line 29 - line 32 *;
 [X]DE3519687  (AREND VEIT, et al) [X] 7 * page 5, line 37 - page 6, line 2; example 1 *;
 [X]US5622983  (HORWELL DAVID C [GB], et al) [X] 7 * column 55, line 61 - line 62 * * column 131; figure 17 *;
 [X]US6124263  (MUCCIOLI GIANPIERO [IT], et al) [X] 7 * claims 9-12 *;
 [X]  - ZEMBOWER DAVID E ET AL, "Enantiospecific syntheses of alpha-(fluoromethyl)tryptophan analogues: Interactions with tryptophan hydroxylase an aromatic L-amino acid decarboxylase.", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1993), Database accession no. PREV199395087823, XP002212214 [X] 1,2,7,8 * abstract *
    [ ] - JOURNAL OF MEDICINAL CHEMISTRY, (1993), vol. 36, no. 3, ISSN 0022-2623, pages 305 - 313
 [XY]  - GILBERT JUDITH A ET AL, "Elevated aromatic-L-amino acid decarboxylase in human carcinoid tumors.", BIOCHEMICAL PHARMACOLOGY, (1995), vol. 50, no. 6, ISSN 0006-2952, pages 845 - 850, XP002212211 [X] 1,7,8 * abstract * * page 848, column R, line 1 - line 5 * [Y] 2-5

DOI:   http://dx.doi.org/10.1016/0006-2952(95)02006-X
 [XY]  - YOFFE J R ET AL, "CHARACTERIZATION OF SEROTONIN UPTAKE IN CULTURED PHEO CHROMO CYTOMA CELLS COMPARISON WITH NOREPINEPHRINE UPTAKE", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1982), Database accession no. PREV198375002324, XP002212215 [X] 7,8 * abstract * [Y] 1-5
    [ ] - MOLECULAR PHARMACOLOGY, (1982), vol. 21, no. 2, ISSN 0026-895X, pages 368 - 373
 [XY]  - TUTTON P J ET AL, "Evaluation of the cytotoxicity of dihydroxytryptamines and 5-hydroxytryptamine antagonists as cytotoxic agents in dimethylhydrazine-induced adenocarcinomata.", MEDLINE, (1978), Database accession no. NLM35286, XP002212216 [X] 7 * abstract * [Y] 1-5,8
    [ ] - CANCER CHEMOTHERAPY AND PHARMACOLOGY. GERMANY, WEST 1978, (1978), vol. 1, no. 4, ISSN 0344-5704, pages 209 - 213
 [Y]  - VON STUDNITZ W, "[Proceedings: Tryptophan hydroxylase inhibition as therapy for carcinoid tumors]", ZEITSCHRIFT FUR KLINISCHE CHEMIE UND KLINISCHE BIOCHEMIE. GERMANY, WEST APR 1972, (197204), vol. 10, no. 4, ISSN 0044-2933, page 181, XP002212212 [Y] 1-5,7,8 * the whole document *
 [Y]  - BAUMGARTEN H G ET AL, "A developmental study of the effects of 5,7-dihydroxytryptamine on regional tryptophan hydroxylase in rat brain.", PSYCHOPHARMACOLOGY COMMUNICATIONS. UNITED STATES 1975, (1975), vol. 1, no. 1, ISSN 0098-616X, pages 75 - 88, XP002212213 [Y] 1-5,7,8 * page 78, line 10 - line 12 * * page 80, line 8 - line 9 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.