Deutsch English Français

Contact

EP1434875

European procedure

Quick help

Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...

News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...

Extract from the Register of European Patents

EP About this file: EP1434875

EP1434875 - GENE POLYMORPHISMS AND RESPONSE TO TREATMENT [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 28.07.2006 Database last updated on 15.07.2024
Most recent event Tooltip	28.07.2006	Application deemed to be withdrawn	published on 30.08.2006 [2006/35]
Applicant(s)	For all designated states SMITHKLINE BEECHAM CORPORATION One Franklin Plaza Philadelphia, PA 19101 / US
	[N/P]
Former [2004/28]	For all designated states SmithKline Beecham Corporation One Franklin Plaza Philadelphia, PA 19101 / US
Inventor(s)	01 / DOW, David, J GlaxoSmithKline, Gunnels Wood Road Stevenage, Hertfordshire SGI 2NY / GB
	02 / DUNCAN, Ben 20225 Bothell-Everett Hwy 2232 Bothell, WA 98012 / US
	03 / HUGHES, Arlene, R GlaxoSmithKline, Five Moore Drive, PO Box 13398 Research Triangle Park, NC 27709 / US
	04 / MANASCO, Penelope 9801 Adlie Drive Wake Forest, NC 27587 / US
	05 / PILLAI, Sreekumar, G GlaxoSmithKline, Five Moore Drive, PO Box 13398 Research Triangle Park, NC 27709 / US
	06 / SPAULDING, Theodore, C GlaxoSmithKline, Five Moore Drive, PO Box 13398 Research Triangle Park, NC 27709 / US
	07 / SPRAGGS, Colin, F GlaxoSmithKline, Gunnels Wood Road Stevenage, Hertfordshire SGI 2NY / GB
	08 / STUBBINS, Michael, GlaxoSmithKline New Frontiers Park N & E, Third Avenue Harlow, Essex CM 19 5AW / GB
	09 / XU, Chun-Fang GlaxoSmithKline, Gunnels Wood Road Stevenage, Hertfordshire SGI 2NY / GB
	[2004/28]
Representative(s)	Thornley, Rachel Mary GlaxoSmithKline Global Patents (CN925.1) 980 Great West Road Brentford, Middlesex TW8 9GS / GB
	[N/P]
Former [2004/28]	Thornley, Rachel Mary GlaxoSmithKline, Corporate Intellectual Property (CN9.25.1) 980 Great West Road Brentford, Middlesex TW8 9GS / GB
Application number, filing date	02757011.8	07.08.2002
	[2004/28]
	WO2002US25060
Priority number, date	US20010313918P	21.08.2001 Original published format: US 313918 P
	US20010337819P	08.11.2001 Original published format: US 337819 P
	[2004/28]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO03018843
	Date:	06.03.2003
	Language:	EN
	[2003/10]
	Type:	A1 Application with search report
	No.:	EP1434875
	Date:	07.07.2004
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 06.03.2003 takes the place of the publication of the European patent application.
	[2004/28]
Search report(s)	International search report - published on:	US	06.03.2003
	(Supplementary) European search report - dispatched on:	EP	08.11.2004
Classification	IPC:	C12Q1/68, C07H21/04	[2004/28]
	CPC:	C12Y104/03004 (EP,US); C07K14/47 (EP,US); C07K14/70571 (EP,US); C12N9/0022 (EP,US); C12Q1/6883 (EP,US)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, SK, TR [2004/28]
Extension states	AL	Not yet paid
	LT	18.03.2004
	LV	18.03.2004
	MK	Not yet paid
	RO	18.03.2004
	SI	18.03.2004
Title	German:	GENPOLYMORPHISMEN UND ANSPRECHEN AUF BEHANDLUNG	[2004/28]
	English:	GENE POLYMORPHISMS AND RESPONSE TO TREATMENT	[2004/28]
	French:	POLYMORPHISMES GENIQUES ET REPONSE A UN TRAITEMENT	[2004/28]
Entry into regional phase	18.03.2004	National basic fee paid
	18.03.2004	Search fee paid
	18.03.2004	Designation fee(s) paid
	18.03.2004	Examination fee paid
Examination procedure	05.03.2003	Request for preliminary examination filed International Preliminary Examining Authority: US
	18.03.2004	Amendment by applicant (claims and/or description)
	18.03.2004	Examination requested [2004/28]
	01.03.2006	Application deemed to be withdrawn, date of legal effect [2006/35]
	10.04.2006	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2006/35]
Fees paid	Renewal fee
	06.08.2004	Renewal fee patent year 03
	Penalty fee
	Additional fee for renewal fee
	31.08.2005	04 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[Y]WO0148246 (UNIV VANDERBILT [US], et al) [Y] 1-21 * the whole document *;
		[Y] - WILLIAMS K V ET AL, "5-HTT gene polymorphism predicts early sibutramine weight loss", INTERNATIONAL JOURNAL OF OBESITY, & 10TH EUROPEAN CONGRESS ON OBESITY OF THE EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY; ANTWERP, BELGIUM; MAY 24-27, 2000, (200005), vol. 24, no. Supplement 1, ISSN 0307-0565, page S41, XP001184089 [Y] 1-21 * the whole document *
		[Y] - HEAL D J ET AL, "SIBUTRAMINE: A NOVEL ANTI-OBESTIY DRUG. A REVIEW OF THE PHARMACOLOGICAL EVIDENCE TO DIFFERENTIATE IT FROM D-AMPHETAMINE AND D-FENFLURAMINE", INTERNATIONAL JOURNAL OF OBESITY, NEWMAN PUBLISHING, LONDON, GB, (199808), vol. 22, no. SUPPL 1, ISSN 0307-0565, pages S18 - S28, XP008005119 [Y] 1-21 * the whole document *
		[Y] - STOEBER GERALD ET AL, "Tourette syndrome and the norepinephrine transporter gene: Results of a systematic mutation screening", AMERICAN JOURNAL OF MEDICAL GENETICS, (19990416), vol. 88, no. 2, ISSN 0148-7299, pages 158 - 163, XP002303021 [Y] 1-21 * the whole document * DOI: http://dx.doi.org/10.1002/(SICI)1096-8628(19990416)88:2<158::AID-AJMG12>3.0.CO;2-W
		[Y] - BOENISCH H ET AL, "The human desipramine-sensitive noradrenaline transporter and the importance of defined amino acids for its function", JOURNAL OF AUTONOMIC PHARMACOLOGY, (199912), vol. 19, no. 6, ISSN 0144-1795, pages 327 - 333, XP009038886 [Y] 1-21 * the whole document *
		[Y] - RUNKEL FABIAN ET AL, "Pharmacological properties of naturally occurring variants of the human norepinephrine transporter", PHARMACOGENETICS, (200007), vol. 10, no. 5, ISSN 0960-314X, pages 397 - 405, XP009038850 [Y] 1-21 * the whole document * DOI: http://dx.doi.org/10.1097/00008571-200007000-00003
		[Y] - PIRKE K M ET AL, "PLASMA NOREPINEPHRINE AFTER A STANDARDIZED TEST MEAL IN ACUTE AND REMITTED PATIENTS WITH ANOREXIA NERVOSA AND IN HEALTHY CONTROLS", BIOLOGICAL PSYCHIATRY, (1992), vol. 31, no. 10, ISSN 0006-3223, pages 1074 - 1077, XP002303022 [Y] 1-21 * the whole document * DOI: http://dx.doi.org/10.1016/0006-3223(92)90102-6
	International search	[A] - STOBER ET AL., "Systematic search for variation in the human norepinephrine transporter gene: identification of five naturally occurring missense mutations and study of association with major psychiatric disorders", AMERICAN JOURNAL OF MEDICAL GENETIS (NEUROPSYCHIATRIC GENETICS), (1996), vol. 67, pages 523 - 532, XP002958567 DOI: http://dx.doi.org/10.1002/(SICI)1096-8628(19961122)67:6<523::AID-AJMG3>3.0.CO;2-I
		[A] - BERTRAND G. WINSBERG ET AL., "Association of the dopamine transporter gene (DAT1) with poor methylphenidate response", J. AM. ACAD. CHILD ADOLESC. PSYCHIATRY, (199912), vol. 38, no. 12, pages 1474 - 1477, XP002958568 DOI: http://dx.doi.org/10.1097/00004583-199912000-00006
		[A] - OKABE ET AL., "Alternative splicing of the C-terminal domain regulates cell surface expression of the NMDA receptor NR1 subunit", THE JOURNAL OF NEUROSCIENCE, (199909), vol. 19, no. 18, pages 7781 - 7792, XP002958570
		[A] - MUNDO ET AL., "Lack of linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and bipolar disorder", AMERICAN JOURNAL OF MEDICAL GENETICS (NEUROPSYCHIATRIC GENETICS), (2000), vol. 96, pages 379 - 383, XP002958569 DOI: http://dx.doi.org/10.1002/1096-8628(20000612)96:3<379::AID-AJMG27>3.0.CO;2-E
		[A] - ERIKSSON ET AL., "Further investigation of citalopram on alcohol consumption in heavy drinkers: responsiveness possibly linked to the DRD2 A2/A2 genotype", ALCOHOL, (200105), vol. 24, no. 1, pages 15 - 23, XP002958571 DOI: http://dx.doi.org/10.1016/S0741-8329(01)00137-9
		[A] - HO ET AL., "An allelic association study of monoamine oxidase B in Parkinson's disease", ANNALS OF NEUROLOGY, (199503), vol. 37, no. 3, pages 403 - 405, XP002958572 DOI: http://dx.doi.org/10.1002/ana.410370318
		[AP] - SERRITTI ET AL., "No association between dopamine D2 and D4 receptor gene variants and antidepressant activity of two selective serotonin reuptake inhibitors", PSYCHIATRY RESEARCH, (200111), vol. 104, pages 195 - 203, XP002958573 DOI: http://dx.doi.org/10.1016/S0165-1781(01)00324-9
		[AP] - ROSMOND ET AL., "Polymorphism in exon 6 of the dopamine D2 receptor gene (DRD2) is associated with elevated blood pressure and personality disorders in men", JOURNAL OF HUMAN HYPERTENSION, (200108), vol. 15, pages 553 - 558, XP002958574 DOI: http://dx.doi.org/10.1038/sj.jhh.1001231

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

Legal notice
Terms of use
24.1.24; 34p