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Extract from the Register of European Patents

EP About this file: EP1434790

EP1434790 - CALCIUM-INFLUX INHIBITORY FACTOR AND METHOD OF ISOLATION THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.10.2007
Database last updated on 31.05.2024
Most recent event   Tooltip11.09.2009Lapse of the patent in a contracting state
New state(s): TR		published on 14.10.2009  [2009/42]
Applicant(s)For all designated states
Eastern Virginia Medical School
825 Fairfax Avenue, Suite 751
Norfolk, VA 23507 / US
[2006/50]
Former [2004/28]For all designated states
Eastern Virginia Medical School
825 Fairfax Avenue, Suite 751
Norfolk, VA 23507 / US
Inventor(s)01 / BUESCHER, E., Stephen
3936 Regal Court
Virginia Beach, VA 23452 / US
 [2004/28]
Representative(s)Lee, Nicholas John, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2004/28]Lee, Nicholas John, et al
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date02757677.611.09.2002
[2004/28]
WO2002US28814
Priority number, dateUS20010322057P12.09.2001         Original published format: US 322057 P
[2004/28]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03022870
Date:20.03.2003
Language:EN
[2003/12]
Type: A1 Application with search report 
No.:EP1434790
Date:07.07.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 20.03.2003 takes the place of the publication of the European patent application.
[2004/28]
Type: B1 Patent specification 
No.:EP1434790
Date:13.12.2006
Language:EN
[2006/50]
Search report(s)International search report - published on:US20.03.2003
(Supplementary) European search report - dispatched on:EP07.10.2004
ClassificationIPC:C07K1/14, C07K1/34, C07K14/47
[2004/47]
CPC:
C07K14/47 (EP,US); A61P29/00 (EP); A61P3/14 (EP)
Former IPC [2004/28]C07K1/14, C07K1/34
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/28]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:DEN CALCIUMEINSTROM HEMMENDER FAKTOR UND VERFAHREN ZU DESSEN ISOLIERUNG[2004/28]
English:CALCIUM-INFLUX INHIBITORY FACTOR AND METHOD OF ISOLATION THEREOF[2004/28]
French:FACTEUR D'INHIBITION D'AFFLUX DE CALCIUM ET METHODE D'ISOLEMENT DUDIT FACTEUR[2004/28]
Entry into regional phase08.04.2004National basic fee paid 
08.04.2004Search fee paid 
08.04.2004Designation fee(s) paid 
08.04.2004Examination fee paid 
Examination procedure03.04.2003Request for preliminary examination filed
International Preliminary Examining Authority: US
08.04.2004Amendment by applicant (claims and/or description)
08.04.2004Examination requested  [2004/28]
08.03.2005Despatch of a communication from the examining division (Time limit: M04)
14.07.2005Reply to a communication from the examining division
02.06.2006Communication of intention to grant the patent
09.10.2006Fee for grant paid
09.10.2006Fee for publishing/printing paid
Opposition(s)14.09.2007No opposition filed within time limit [2007/47]
Fees paidRenewal fee
23.09.2004Renewal fee patent year 03
21.09.2005Renewal fee patent year 04
27.09.2006Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY13.12.2006
CZ13.12.2006
EE13.12.2006
SK13.12.2006
TR13.12.2006
BG13.03.2007
GR14.03.2007
PT14.05.2007
AT11.09.2007
FI11.09.2007
IE11.09.2007
LU11.09.2007
ES12.09.2007
SE12.09.2007
[2009/42]
Former [2009/38]CY13.12.2006
CZ13.12.2006
EE13.12.2006
SK13.12.2006
BG13.03.2007
GR14.03.2007
PT14.05.2007
AT11.09.2007
FI11.09.2007
IE11.09.2007
LU11.09.2007
ES12.09.2007
SE12.09.2007
Former [2009/09]CZ13.12.2006
EE13.12.2006
SK13.12.2006
BG13.03.2007
GR14.03.2007
PT14.05.2007
AT11.09.2007
FI11.09.2007
IE11.09.2007
ES12.09.2007
SE12.09.2007
Former [2008/50]CZ13.12.2006
SK13.12.2006
BG13.03.2007
GR14.03.2007
PT14.05.2007
AT11.09.2007
FI11.09.2007
IE11.09.2007
SE12.09.2007
Former [2008/45]CZ13.12.2006
SK13.12.2006
BG13.03.2007
GR14.03.2007
PT14.05.2007
FI11.09.2007
IE11.09.2007
SE12.09.2007
Former [2008/25]CZ13.12.2006
SK13.12.2006
BG13.03.2007
GR14.03.2007
PT14.05.2007
FI11.09.2007
SE12.09.2007
Former [2008/22]CZ13.12.2006
SK13.12.2006
BG13.03.2007
GR14.03.2007
PT14.05.2007
SE12.09.2007
Former [2007/46]CZ13.12.2006
SK13.12.2006
BG13.03.2007
PT14.05.2007
Former [2007/39]CZ13.12.2006
BG13.03.2007
PT14.05.2007
Former [2007/25]BG13.03.2007
Documents cited:Search[PX]  - BUESCHER STEPHEN ET AL, "Human milk exposure causes transient rises in intracellular free Ca++ levels, depletion of intracellular Ca++ stores and blockade of Ca++ influx in human polymorphonuclear leukocytes (PMN)", PEDIATRIC RESEARCH, & ANNUAL MEETING OF THE PEDIATRIC SOCIETIES'; BALTIMORE, MD, USA; MAY 04-07, 2002, (200204), vol. 51, no. 4 Part 2, ISSN 0031-3998, page 273A, XP009036583 [PX] 1-16 * the whole document *
 [X]  - BUESCHER STEPHEN ET AL, "Blockade of Ca++ influx by human milk factor(s) selectively affects polymorphonuclear leukocyte functions", PEDIATRIC RESEARCH, & JOINT MEETING OF THE PEDIATRIC ACADEMIC SOCIETIES AND THE AMERICAN ACADEMY OF PEDIATRICS.; BOSTON, MASSACHUSETTS, USA; MAY 12-16, 2000, (200004), vol. 47, no. 4 Part 2, ISSN 0031-3998, page 390A, XP009036595 [X] 1-18 * the whole document *
 [X]  - CHACON-CRUZ ENRIQUE ET AL, "Human milk exposure blocks calcium influx into human polymorphonuclear leukocytes", PEDIATRIC RESEARCH, & ANNUAL MEETING OF THE AMERICAN PEDIATRIC SOCIETY AND THE SOCIETY FOR PEDIATRIC RESEARCH; NEW ORLEANS, LOUISIANA, USA; MAY 1-5, 1998, (199804), vol. 43, no. 4 PART 2, ISSN 0031-3998, page 7A, XP009036624 [X] 1-18 * the whole document *
 [A]  - CHACON-CRUZ ENRIQUE ET AL, "Human milk's effects on releasing Ca++ from neutrophil internal stores are G-protein mediated and membrane potential dependent", PEDIATRIC RESEARCH, & JOINT MEETING OF THE PEDIATRIC ACADEMIC SOCIETIES AND THE AMERICAN ACADEMY OF PEDIATRICS.; BOSTON, MASSACHUSETTS, USA; MAY 12-16, 2000, (200004), vol. 47, no. 4 Part 2, ISSN 0031-3998, page 16A, XP009036594 [A] 1-18
 [A]  - CHACON-CRUZ ENRIQUE ET AL, "Human milk effects on neutrophil calcium metabolism: Blockade of calcium influx after agonist stimulation", PEDIATRIC RESEARCH, (199908), vol. 46, no. 2, ISSN 0031-3998, pages 200 - 207, XP009036593 [A] 1-18
 [A]  - BUESCHER E STEPHEN ET AL, "Human milk anti-inflammatory component contents during acute mastitis", CELLULAR IMMUNOLOGY, (20010615), vol. 210, no. 2, ISSN 0008-8749, pages 87 - 95, XP002296441 [A] 1-18

DOI:   http://dx.doi.org/10.1006/cimm.2001.1813
International search[A]WO9529933  (GROPEP PTY LTD [AU], et al);
 [A]US5595738  (POMATO NICHOLAS [US], et al);
 [Y]US5667797  (PETERSON JERRY A [US], et al);
 [A]US6177550  (MEYER HANS [CH], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.