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Extract from the Register of European Patents

EP About this file: EP1425304

EP1425304 - G-CSF CONJUGATES [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  06.02.2015
Database last updated on 04.06.2024
Most recent event   Tooltip06.02.2015Revocation of patentpublished on 11.03.2015  [2015/11]
Applicant(s)For all designated states
Maxygen, Inc.
515, Galveston Drive
Redwood City, CA 94063 / US
[2010/19]
Former [2004/24]For all designated states
Maxygen Holdings Ltd. c/o Close Brothers (Cayman) Limited
103 South Church Street, P.O.Box 1034 GT
Grand Cayman. British West Indies / KY
Inventor(s)01 / NISSEN, Torben, Lauesgaard
421 Forest Avenue
Palo Alto, CA 94301 / US
02 / ANDERSEN, Kim, Vilbour
Karlstads Allé 7
DK-2700 Broenshoej / DK
03 / HANSEN, Christian, Karsten
Rungsted Strandvej 19
DK-2950 Vedbaek / DK
04 / MIKKELSEN, Jan, Möller
Soloesevej 24
DK-2820 Gentofte / DK
05 / SCHAMBYE, Hans, Thalsgärd
Pelargonievej 21
DK-2000 Frederiksberg / DK
 [2010/21]
Former [2004/24]01 / NISSEN, Torben, Lauesgaard
421 Forest Avenue
Palo Alto, CA 94301 / US
02 / ANDERSEN, Kim, Vilbour
Karlstads Allé 7
DK-2700 Broenshoej / DK
03 / HANSEN, Christian, Karsten
Rungsted Strandvej 19
DK-2950 Vedbaek / DK
04 / MIKKELSEN, Jan, M ller
Soloesevej 24
DK-2820 Gentofte / DK
05 / SCHAMBYE, Hans, Thalsg rd
Pelargonievej 21
DK-2000 Frederiksberg / DK
Representative(s)Chapman, Desmond Mark, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2012/51]Chapman, Desmond Mark, et al
Carpmaels & Ransford
One Southampton Row
London WC1B 5HA / GB
Former [2008/16]Hallybone, Huw George, et al
Carpmaels and Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Former [2008/10]Carpmaels & Ransford
One Southampton Row London
WC1B 5HA / GB
Former [2004/24]Salka, Jeffrey, et al
Maxygen ApS, Agern Allé 1, Danish Science Park
2970 Hoersholm / DK
Application number, filing date02760160.810.07.2002
[2004/24]
WO2002DK00482
Priority number, dateUS2001090419611.07.2001         Original published format: US 904196
DK2002000044722.03.2002         Original published format: DK 200200447
DK2002000070808.05.2002         Original published format: DK 200200708
[2004/24]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03006501
Date:23.01.2003
Language:EN
[2003/04]
Type: A2 Application without search report 
No.:EP1425304
Date:09.06.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 23.01.2003 takes the place of the publication of the European patent application.
[2004/24]
Type: B1 Patent specification 
No.:EP1425304
Date:26.05.2010
Language:EN
[2010/21]
Type: B9 Corrected patent specification 
No.:EP1425304
Date:08.09.2010
[2010/36]
Search report(s)International search report - published on:EP25.03.2004
ClassificationIPC:A61K47/48, A61P7/00
[2009/49]
CPC:
C07K14/53 (EP,KR,US); A61K38/00 (KR); A61K47/60 (EP,US);
A61P31/00 (EP); A61P37/00 (EP); A61P7/00 (EP);
A61P7/06 (EP); C07K14/00 (KR) (-)
Former IPC [2004/28]A61K47/48
Former IPC [2004/24]C07K14/53
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/24]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:G-CSF KONJUGATE[2004/24]
English:G-CSF CONJUGATES[2004/24]
French:CONJUGUES DE G-CSF[2004/24]
Entry into regional phase11.02.2004National basic fee paid 
27.09.2004Designation fee(s) paid 
27.09.2004Examination fee paid 
Examination procedure08.01.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
27.01.2004Amendment by applicant (claims and/or description)
27.09.2004Examination requested  [2004/48]
19.10.2007Despatch of a communication from the examining division (Time limit: M04)
21.02.2008Reply to a communication from the examining division
10.07.2008Despatch of a communication from the examining division (Time limit: M04)
03.11.2008Reply to a communication from the examining division
15.10.2009Cancellation of oral proceeding that was planned for 29.10.2009
29.10.2009Date of oral proceedings
29.10.2009Date of oral proceedings (cancelled)
13.11.2009Communication of intention to grant the patent
22.03.2010Fee for grant paid
22.03.2010Fee for publishing/printing paid
Opposition(s)Opponent(s)01  28.02.2011  27.05.2011  ADMISSIBLE
Amgen Inc.
One Amgen Center Drive
Thousand Oaks, CA 91320-1799 / US
Opponent's representative
Uexküll & Stolberg
Partnerschaft von
Patent- und Rechtsanwälten mbB
Beselerstrasse 4
22607 Hamburg / DE
 [N/P]
Former [2011/14]
Opponent(s)01  28.02.2011   
Amgen Inc.
One Amgen Center Drive
Thousand Oaks, CA 91320-1799 / US
Opponent's representative
UEXKÜLL & STOLBERG
Patentanwälte Beselerstrasse 4
22607 Hamburg / DE
01.06.2011Invitation to proprietor to file observations on the notice of opposition
07.10.2011Reply of patent proprietor to notice(s) of opposition
27.10.2011Communication of observations of patent proprietor (Time limit: M07)
06.06.2012Reply of parties involved to observations of patent proprietor
28.05.2013Legal effect of interlocutory decision in opposition
28.05.2013Date of oral proceedings
18.06.2013Despatch of interlocutory decision in opposition
18.06.2013Despatch of minutes of oral proceedings
28.01.2014Despatch of communication that the patent will be maintained as amended
29.09.2014Despatch of communication that the patent will be revoked
09.10.2014Legal effect of revocation of patent [2015/11]
Appeal following opposition28.08.2013Appeal received No.  T1835/13
22.10.2013Result of appeal procedure: appeal of the opponent withdrawn
27.08.2013Appeal received No.  T1835/13
22.10.2013Result of appeal procedure: appeal of the opponent withdrawn
Fees paidRenewal fee
02.08.2004Renewal fee patent year 03
01.08.2005Renewal fee patent year 04
31.07.2006Renewal fee patent year 05
31.07.2007Renewal fee patent year 06
10.07.2008Renewal fee patent year 07
08.07.2009Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT26.05.2010
BE26.05.2010
CY26.05.2010
CZ26.05.2010
DK26.05.2010
EE26.05.2010
FI26.05.2010
IT26.05.2010
NL26.05.2010
SE26.05.2010
SK26.05.2010
TR26.05.2010
IE10.07.2010
LU10.07.2010
CH31.07.2010
LI31.07.2010
MC31.07.2010
BG26.08.2010
GR27.08.2010
ES06.09.2010
PT27.09.2010
[2013/46]
Former [2013/42]AT26.05.2010
BE26.05.2010
CY26.05.2010
CZ26.05.2010
DK26.05.2010
EE26.05.2010
FI26.05.2010
IT26.05.2010
NL26.05.2010
SE26.05.2010
SK26.05.2010
TR26.05.2010
IE10.07.2010
LU10.07.2010
CH31.07.2010
LI31.07.2010
MC31.07.2010
BG26.08.2010
GR27.08.2010
PT27.09.2010
Former [2011/35]AT26.05.2010
BE26.05.2010
CY26.05.2010
CZ26.05.2010
DK26.05.2010
EE26.05.2010
FI26.05.2010
IT26.05.2010
NL26.05.2010
SE26.05.2010
SK26.05.2010
IE10.07.2010
CH31.07.2010
LI31.07.2010
MC31.07.2010
GR27.08.2010
PT27.09.2010
Former [2011/20]AT26.05.2010
BE26.05.2010
CY26.05.2010
CZ26.05.2010
DK26.05.2010
EE26.05.2010
FI26.05.2010
IT26.05.2010
NL26.05.2010
SE26.05.2010
SK26.05.2010
CH31.07.2010
LI31.07.2010
MC31.07.2010
GR27.08.2010
PT27.09.2010
Former [2011/14]AT26.05.2010
BE26.05.2010
CY26.05.2010
CZ26.05.2010
DK26.05.2010
EE26.05.2010
FI26.05.2010
IT26.05.2010
NL26.05.2010
SE26.05.2010
SK26.05.2010
MC31.07.2010
GR27.08.2010
PT27.09.2010
Former [2011/11]AT26.05.2010
CY26.05.2010
CZ26.05.2010
DK26.05.2010
EE26.05.2010
FI26.05.2010
NL26.05.2010
SE26.05.2010
SK26.05.2010
MC31.07.2010
GR27.08.2010
PT27.09.2010
Former [2011/10]AT26.05.2010
CY26.05.2010
CZ26.05.2010
DK26.05.2010
EE26.05.2010
FI26.05.2010
NL26.05.2010
SE26.05.2010
SK26.05.2010
GR27.08.2010
PT27.09.2010
Former [2011/08]AT26.05.2010
CY26.05.2010
DK26.05.2010
EE26.05.2010
FI26.05.2010
NL26.05.2010
SE26.05.2010
GR27.08.2010
PT27.09.2010
Former [2011/07]AT26.05.2010
CY26.05.2010
DK26.05.2010
FI26.05.2010
NL26.05.2010
SE26.05.2010
GR27.08.2010
Former [2011/05]AT26.05.2010
CY26.05.2010
FI26.05.2010
SE26.05.2010
GR27.08.2010
Former [2011/01]AT26.05.2010
FI26.05.2010
SE26.05.2010
GR27.08.2010
Former [2010/50]AT26.05.2010
FI26.05.2010
SE26.05.2010
Former [2010/49]AT26.05.2010
SE26.05.2010
Cited inInternational search[X]WO9967291  (IMMUNEX CORP [US], et al) [X] 1 * page 5, line 20; example 3 *;
 [PX]WO0151510  (MAXYGEN APS [DK]) [PX] 1 * claim - *;
 [PX]WO0236626  (MAXYGEN APS [DK], et al) [PX] 1-26* claim - *;
 [X]  - DE HAAN G ET AL, "Efficient mobilization of haematopoietic progenitors after a single injection of pegylated recombinant human granulocyte colony-stimulating factor in mouse strains with distinct marrow-cell pool sizes.", BRITISH JOURNAL OF HAEMATOLOGY. SEP 2000, (200009), vol. 110, no. 3, ISSN 0007-1048, pages 638 - 646, XP001151897 [X] 1 * abstract *

DOI:   http://dx.doi.org/10.1046/j.1365-2141.2000.02252.x
ExaminationUS4904584
by applicantUS4810643
 US4904584
 US5122614
 US5824778
 WO9955377
 US5985265
 WO9967291
 WO0151510
    - GATA ET AL., NATURE, (1986), vol. 319, pages 415 - 418
    - ROBINSON; WITTRUP, BIOTECHNOL. PROG., (1985), vol. 11, pages 171 - 177
    - BOWEN ET AL., EXPERIMENTAL HEMATOLOGY, (1999), vol. 27, pages 425 - 432
    - DE HAAN ET AL., BRITISH JOURNAL OF HAEMATOLOGY, (2000), vol. 110, pages 638 - 646
    - "Mullerian Inhibiting Substance And Expression of the Human Gene In Animal Cells", CELL, (1986), vol. 45, pages 685 - 98
    - P.R. RUSSELL, GENE, (1985), vol. 40, pages 125 - 130
    - D. METCALF; N. A. NICOLA, The hemopoietic colony-stimulating jactors, CAMBRIDGE UNIVERSITY PRESS, (1995), pages 50 - 51
    - C. S. BAE ET AL., APPL. MICROBIOL. BIOTECHNOL, (1999), vol. 52, pages 338 - 344
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.