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Extract from the Register of European Patents

EP About this file: EP1482928

EP1482928 - MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS,COMPOSITIONS AND USES RELATED THERETO [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.07.2010
Database last updated on 02.08.2024
Most recent event   Tooltip19.10.2012Lapse of the patent in a contracting state
New state(s): TR		published on 21.11.2012  [2012/47]
Applicant(s)For all designated states
Curis, Inc.
45 Moulton Street
Cambridge, MA 02138 / US
[2009/51]
Former [2004/50]For all designated states
Curis, Inc.
61 Moulton Street
Cambridge, MA 02138 / US
Inventor(s)01 / RUBIN, Lee
2 Barnstable Road
Wellesley, MA 02481 / US
02 / GUICHERIT, Oivin, M.
28 Hamilton Road
Belmont, MA 02478 / US
03 / PRICE, Stephen
25 Eskdale Road, Stoke Mandeville, Aylesbury
Bucks HP22 5UJ / GB
04 / BOYD, Edward A.
61 Tamar Way, Didcot
Oxfordshire OX11 7QH / GB
 [2004/50]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2008/35]Vossius & Partner
Siebertstrasse 3
81675 München / DE
Former [2004/50]VOSSIUS & PARTNER
Siebertstrasse 4
81675 München / DE
Application number, filing date02763383.329.07.2002
[2004/50]
WO2002US24073
Priority number, dateUS20010308449P27.07.2001         Original published format: US 308449 P
US20010338031P13.11.2001         Original published format: US 338031 P
[2004/50]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03011219
Date:13.02.2003
Language:EN
[2003/07]
Type: A2 Application without search report 
No.:EP1482928
Date:08.12.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 13.02.2003 takes the place of the publication of the European patent application.
[2004/50]
Type: B1 Patent specification 
No.:EP1482928
Date:23.09.2009
Language:EN
[2009/39]
Search report(s)International search report - published on:US23.09.2004
(Supplementary) European search report - dispatched on:EP25.08.2005
ClassificationIPC:A61K31/415, A61K31/4184, A61K31/423, A61K31/428, A61P35/00
[2005/40]
CPC:
C07D263/57 (EP,US); A61K31/4184 (EP,KR,US); A61K31/395 (EP,US);
A61K31/423 (EP,US); A61K31/428 (EP,US); A61P1/16 (EP);
A61P11/00 (EP); A61P15/00 (EP); A61P17/00 (EP);
A61P17/14 (EP); A61P19/00 (EP); A61P21/00 (EP);
A61P25/00 (EP); A61P35/00 (EP); A61P43/00 (EP);
A61P7/00 (EP); C07D235/18 (EP,US); C07D401/12 (EP,US);
C07D405/12 (EP,US); C07D413/12 (EP,US); C07D471/04 (EP,US) (-)
Former IPC [2004/50]A61K31/415
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/50]
Extension statesAL26.02.2004
LT26.02.2004
LV26.02.2004
MK26.02.2004
RO26.02.2004
SI26.02.2004
TitleGerman:VERMITTLER VON IGEL-SIGNALPFADEN, ZUSAMMENSETZUNGEN UND RELEVANTE VERWENDUNGSZWECKE[2004/50]
English:MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS,COMPOSITIONS AND USES RELATED THERETO[2004/50]
French:MEDIATEURS DES VOIES DE SIGNALISATION HEDGEHOG, COMPOSITIONS ASSOCIEES ET UTILISATIONS DE CES DERNIERES[2004/50]
Entry into regional phase26.02.2004National basic fee paid 
26.02.2004Search fee paid 
26.02.2004Designation fee(s) paid 
26.02.2004Examination fee paid 
Examination procedure04.02.2003Request for preliminary examination filed
International Preliminary Examining Authority: US
26.02.2004Amendment by applicant (claims and/or description)
26.02.2004Examination requested  [2004/50]
05.09.2006Despatch of a communication from the examining division (Time limit: M06)
13.03.2007Reply to a communication from the examining division
24.05.2007Despatch of a communication from the examining division (Time limit: M06)
23.11.2007Reply to a communication from the examining division
08.02.2008Despatch of a communication from the examining division (Time limit: M02)
18.04.2008Reply to a communication from the examining division
30.05.2008Despatch of a communication from the examining division (Time limit: M02)
02.07.2008Reply to a communication from the examining division
10.12.2008Communication of intention to grant the patent
20.04.2009Fee for grant paid
20.04.2009Fee for publishing/printing paid
Opposition(s)24.06.2010No opposition filed within time limit [2010/35]
Fees paidRenewal fee
22.07.2004Renewal fee patent year 03
20.07.2005Renewal fee patent year 04
27.07.2006Renewal fee patent year 05
13.07.2007Renewal fee patent year 06
14.07.2008Renewal fee patent year 07
10.07.2009Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT23.09.2009
BE23.09.2009
BG23.09.2009
CY23.09.2009
CZ23.09.2009
DK23.09.2009
EE23.09.2009
FI23.09.2009
IT23.09.2009
NL23.09.2009
SE23.09.2009
SK23.09.2009
TR23.09.2009
GR24.12.2009
ES03.01.2010
PT25.01.2010
[2012/47]
Former [2012/41]AT23.09.2009
BE23.09.2009
BG23.09.2009
CY23.09.2009
CZ23.09.2009
DK23.09.2009
EE23.09.2009
FI23.09.2009
IT23.09.2009
NL23.09.2009
SE23.09.2009
SK23.09.2009
GR24.12.2009
ES03.01.2010
PT25.01.2010
Former [2011/14]AT23.09.2009
BE23.09.2009
CY23.09.2009
CZ23.09.2009
DK23.09.2009
EE23.09.2009
FI23.09.2009
IT23.09.2009
NL23.09.2009
SE23.09.2009
SK23.09.2009
GR24.12.2009
ES03.01.2010
PT25.01.2010
Former [2010/48]AT23.09.2009
BE23.09.2009
CY23.09.2009
CZ23.09.2009
DK23.09.2009
EE23.09.2009
FI23.09.2009
NL23.09.2009
SE23.09.2009
SK23.09.2009
GR24.12.2009
ES03.01.2010
PT25.01.2010
Former [2010/35]AT23.09.2009
BE23.09.2009
CY23.09.2009
CZ23.09.2009
DK23.09.2009
EE23.09.2009
FI23.09.2009
NL23.09.2009
SE23.09.2009
SK23.09.2009
ES03.01.2010
PT25.01.2010
Former [2010/32]AT23.09.2009
BE23.09.2009
CY23.09.2009
CZ23.09.2009
EE23.09.2009
FI23.09.2009
NL23.09.2009
SE23.09.2009
SK23.09.2009
ES03.01.2010
PT25.01.2010
Former [2010/30]AT23.09.2009
BE23.09.2009
CY23.09.2009
CZ23.09.2009
EE23.09.2009
FI23.09.2009
SE23.09.2009
SK23.09.2009
ES03.01.2010
PT25.01.2010
Former [2010/28]BE23.09.2009
CY23.09.2009
CZ23.09.2009
EE23.09.2009
FI23.09.2009
SE23.09.2009
SK23.09.2009
ES03.01.2010
PT25.01.2010
Former [2010/24]CY23.09.2009
CZ23.09.2009
EE23.09.2009
FI23.09.2009
SE23.09.2009
SK23.09.2009
ES03.01.2010
PT25.01.2010
Former [2010/22]CY23.09.2009
CZ23.09.2009
EE23.09.2009
FI23.09.2009
SE23.09.2009
ES03.01.2010
PT25.01.2010
Former [2010/20]CY23.09.2009
EE23.09.2009
FI23.09.2009
SE23.09.2009
ES03.01.2010
Former [2010/19]CY23.09.2009
FI23.09.2009
SE23.09.2009
ES03.01.2010
Former [2010/16]CY23.09.2009
FI23.09.2009
SE23.09.2009
Former [2010/09]FI23.09.2009
SE23.09.2009
Former [2010/08]SE23.09.2009
Documents cited:Search[XY]EP0719765  (MITSUI TOATSU CHEMICALS [JP]) [X] 1,2,5,6,13-17,19 * table 1 * * page 18, line 33 - line 35 * [Y] 1-23;
 [X]WO9626932  (CANCER RES CAMPAIGN TECH [GB], et al) [X] 1,2,5,6,14-17 * examples 13,14,16,17,23 * * abstract * * page 31, paragraph L *;
 [X]WO9817267  (ZYMOGENETICS INC [US], et al) [X] 1,2,5,6,14-19 * figure 69/140; examples 1,2 * * figure 70/146; examples 2,3 * * figure 72/146; example 2 * * figure 73/146; examples 1-3 * * figure 75/146; example 3 * * figure 82/146; examples 2-4 * * figure 86/146; example 4 * * figure 87/146; example 3 * * figure 88/146; examples 2,3 * * figure 89/146; example 1 * * figures 5a,5c * * abstract *;
 [X]WO9961019  (AVANIR PHARMACEUTICALS [US]) [X] 1,2,5,6,14-17,19 * page 1, paragraph 1 * * claim 1.3 *;
 [A]WO0119800  (CURIS INC [US]) [A] 1-23* the whole document *;
 [E]WO02072090  (AVANIR PHARMACEUTICALS [US]) [E] 1,2,14-17,19 * paragraphs [0076] , [0097] , [0120] * * paragraphs [0014] , [0056] *;
 [X]  - CHUA M S ET AL, "Antitumor benzothiazoles. 7. Synthesis of 2-(4-acylaminophenyl)benzothiazoles and investigations into the role of acetylation in the antitumor activities of the parent amines.", JOURNAL OF MEDICINAL CHEMISTRY. 11 FEB 1999, (19990211), vol. 42, no. 3, ISSN 0022-2623, pages 381 - 392, XP002340530 [X] 5,6,14-18,21-23 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm981076x
 [PY]  - CHEN J K ET AL, "Small molecule modulation of Smoothened activity", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (20021029), vol. 99, no. 22, ISSN 0027-8424, pages 14071 - 14076, XP002251705 [PY] 1-23 * figure 3 * * abstract *

DOI:   http://dx.doi.org/10.1073/pnas.182542899
International search[X]US5641764  (MARTIN ROGER FRANCIS [AU], et al);
 [Y]  - FUKAZAWA ET AL, "Effects of herbimycin A and various sulfhydryl reagents on p60v-src kinase activity in vitro", CAPLUS, Database accession no. 1991:55404, XP002980785
    [ ] - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (1990), vol. 173, no. 1, pages 276 - 282
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.