blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP1438390

EP1438390 - CIRCADIAN CONTROL OF STEM/PROGENITOR CELL SELF-RENEWAL AND DIFFERENTIATION AND OF CLOCK CONTROLLED GENE EXPRESSION [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.06.2007
Database last updated on 30.10.2024
Most recent event   Tooltip15.06.2007Application deemed to be withdrawnpublished on 18.07.2007  [2007/29]
Applicant(s)For all designated states
UNIVERSITY OF ROCHESTER
Office of Technology Transfer, 518 Hylan Building
Rochester, NY 14627-0140 / US
[N/P]
Former [2004/30]For all designated states
UNIVERSITY OF ROCHESTER
Office of Technology Transfer, 518 Hylan Building
Rochester, NY 14627-0140 / US
Inventor(s)01 / WU, J., H., David
21 Framingham Lane
Pittsford, NY 14534 / US
02 / CHEN, Yi-Guang
60 Crittenden Blvd., 1134
Rochester, NY 14620 / US
03 / MANTALARIS, Athanassios
4 Regal Way, Kenton
Harrow, Middlesex HA3 0RX / GB
04 / HECKMAN, Matthew
367 Quinby Road
Rochester, NY 14623 / US
 [2004/30]
Representative(s)Miles, John Stephen
Potter Clarkson LLP The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
[N/P]
Former [2004/30]Miles, John Stephen
Eric Potter Clarkson, Park View House, 58 The Ropewalk
Nottingham NG1 5DD / GB
Application number, filing date02766335.023.09.2002
[2004/30]
WO2002US30060
Priority number, dateUS20010324190P21.09.2001         Original published format: US 324190 P
[2004/30]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03025151
Date:27.03.2003
Language:EN
[2003/13]
Type: A2 Application without search report 
No.:EP1438390
Date:21.07.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 27.03.2003 takes the place of the publication of the European patent application.
[2004/30]
Search report(s)International search report - published on:US04.09.2003
(Supplementary) European search report - dispatched on:EP08.04.2005
ClassificationIPC:C12N5/00, C12N5/02, C12N5/06
[2004/30]
CPC:
C12N5/0647 (EP,US); A61P31/04 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P37/04 (EP); A61P7/00 (EP);
C12N2501/40 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/30]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:ZIRCADIANE KONTROLLE DER SELBSTERNEUERUNG UND DIFFERENZIERUNG VON STAMM-/VORLÄUFERZELLEN UND DER ZEITLICH KONTROLLIERTEN GENEXPRESSION[2004/30]
English:CIRCADIAN CONTROL OF STEM/PROGENITOR CELL SELF-RENEWAL AND DIFFERENTIATION AND OF CLOCK CONTROLLED GENE EXPRESSION[2004/30]
French:CONTROLE BIOLOGIQUE DE L'AUTO-REGENERESCENCE DE CELLULES SOUCHES OU PRECURSEURS, DE LEUR DIFFERENTIATION ET DE L'EXPRESSION GENIQUE REGULEE PAR HORLOGE[2004/30]
Entry into regional phase21.04.2004National basic fee paid 
21.04.2004Search fee paid 
21.04.2004Designation fee(s) paid 
21.04.2004Examination fee paid 
Examination procedure18.04.2003Request for preliminary examination filed
International Preliminary Examining Authority: US
21.04.2004Amendment by applicant (claims and/or description)
21.04.2004Examination requested  [2004/30]
13.09.2006Despatch of a communication from the examining division (Time limit: M04)
24.01.2007Application deemed to be withdrawn, date of legal effect  [2007/29]
01.03.2007Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2007/29]
Fees paidRenewal fee
06.09.2004Renewal fee patent year 03
05.09.2005Renewal fee patent year 04
07.08.2006Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]  - ZHENG BINHAI ET AL, "Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock", CELL, (200106), vol. 105, no. 5, ISSN 0092-8674, pages 683 - 694, XP002308162 [X] 1,2,4-8,22,33-35,37 * abstract; results; discussion; *

DOI:   http://dx.doi.org/10.1016/S0092-8674(01)00380-4
 [X]  - CHEN YG ET AL, "Expression of mPer1 and mPer2, two mammalian clock genes, in murine bone marrow", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (20000924), vol. 276, no. 2, ISSN 0006-291X, pages 724 - 728, XP002308163 [X] 1,2,4-8,22,33-35,37 * abstract, results; discussion; *

DOI:   http://dx.doi.org/10.1006/bbrc.2000.3536
 [X]  - PERPOINT B ET AL, "In vitro chronopharmacology of recombinant mouse IL-3, mouse GM-CSF, and human G-CSF on murine myeloid progenitor cells", EXPERIMENTAL HEMATOLOGY (CHARLOTTESVILLE), (1995), vol. 23, no. 4, ISSN 0301-472X, pages 362 - 368, XP009039851 [X] 1,2,4-8,22,33-35,37 * abstract; discussion; *
 [X]  - WOOD P A ET AL, "Distinct circadian time structures characterize myeloid and erythroid progenitor and multipotential cell clonogenicity as well as marrow precursor proliferation dynamics", EXPERIMENTAL HEMATOLOGY, NEW YORK, NY, US, (199806), vol. 26, no. 6, ISSN 0301-472X, pages 523 - 533, XP009039359 [X] 1,2,4-8,22,33-35,37 * abstract; results; discussion *
 [A]  - YAMAGUCHI S ET AL, "Role of DBP in the circadian oscillatory mechanism", MOLECULAR AND CELLULAR BIOLOGY, (200007), vol. 20, no. 13, ISSN 0270-7306, pages 4773 - 4781, XP002308164 [A] 1,2,4-8,22,33-35,37 * abstract; *

DOI:   http://dx.doi.org/10.1128/MCB.20.13.4773-4781.2000
 [A]  - MELOTTI P ET AL, "The transcription factors c-myb and GATA-2 act independently in the regulation of normal hematopoiesis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (1996), vol. 93, no. 11, ISSN 0027-8424, pages 5313 - 5318, XP002308165 [A] 1,2,4-8,22,33-35,37 * abstract; results; discussion; *

DOI:   http://dx.doi.org/10.1073/pnas.93.11.5313
International search[X]  - D'HONDT L. ET AL., "Definitive evidence for the influence of circadian rhythm on bone marrow (BM) stem cell engraftability", BLOOD, vol. 94,, (19991115), ABSTRACT #4649, XP002967179
 [X]  - KRIZANAC-BENGEZ L. ET AL., "Circadian variations of the CFU-GM content in complete and in non-adherent cell populations of mouse bone marrow cells", PERIODICUM BIOLOGORUM, vol. 96, no. 3, (1994), page 272, ABSTRACT #W4-7, XP002965448
 [Y]  - EARNEST D.J. ET AL., "Immortal time: circadian clock properties of rat suprachiasmatic cell lines", SCIENCE, (19990129), vol. 283, pages 693 - 695, XP002967501

DOI:   http://dx.doi.org/10.1126/science.283.5402.693
 [Y]  - BJARNASON G.A. ET AL., "Circadian variation of cell peroliferation and cell cycle protein expression in man: clinical implications", PROGRESS N CELL CYCLE RESEARCH, (2000), vol. 4, pages 193 - 206, XP002967502
 [X]  - SMAALAND R., "Circadian rhythm of cell division", PROGRESS IN CELL CYCLE RESEARCH, (1996), vol. 2, pages 241 - 266, XP002967503
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.