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Extract from the Register of European Patents

EP About this file: EP1450605

EP1450605 - COMPOSITION TO ALTER BONE PROPERTIES IN A SUBJECT [Right-click to bookmark this link]
Former [2004/36]A COMPOSITION AND METHOD TO ALTER LEAN BODY MASS AND BONE PROPERTIES IN A SUBJECT
[2011/02]
StatusNo opposition filed within time limit
Status updated on  12.10.2012
Database last updated on 29.06.2024
Most recent event   Tooltip18.04.2014Lapse of the patent in a contracting state
New state(s): TR		published on 21.05.2014  [2014/21]
Applicant(s)For all designated states
BAYLOR COLLEGE OF MEDICINE
One Baylor Plaza
Houston, TX 77030 / US
[2004/36]
Inventor(s)01 / DRAGHIA-AKLI, Ruxandra
61 avenue de l'Observatoire
Brussels 1180 / BE
02 / SCHWARTZ, Robert, J.
4019 Marlowe
Houston, TX 77005 / US
 [2011/32]
Former [2004/36]01 / DRAGHIA-AKLI, Ruxandra
5215 Starkridge Drive
Houston, TX 77035 / US
02 / SCHWARTZ, Robert, J.
4019 Marlowe
Houston, TX 77005 / US
Representative(s)Bassil, Nicholas Charles, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2010/02]Bassil, Nicholas Charles, et al
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ / GB
Former [2009/50]Bassil, Nicholas Charles, et al
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ / GB
Former [2009/49]Bassil, Nicholas Charles
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ / GB
Former [2004/36]Fisher, Adrian John, et al
Carpmaels & Ransford, 43-45 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date02782239.425.10.2002
[2004/36]
WO2002US34275
Priority number, dateUS20010357808P26.10.2001         Original published format: US 357808 P
[2004/36]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03038112
Date:08.05.2003
Language:EN
[2003/19]
Type: A2 Application without search report 
No.:EP1450605
Date:01.09.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 08.05.2003 takes the place of the publication of the European patent application.
[2004/36]
Type: B1 Patent specification 
No.:EP1450605
Date:07.12.2011
Language:EN
[2011/49]
Search report(s)International search report - published on:US06.11.2003
(Supplementary) European search report - dispatched on:EP14.12.2006
ClassificationIPC:A01N37/18, A01N43/04, A01N63/00, A61K31/70, A61K38/00, A61K38/31, A61K48/00, C07K16/00, C07K17/00, C07K5/00, C07K7/00
[2004/36]
CPC:
C07K14/60 (EP,US); A61K38/25 (EP,US); A61K48/0041 (EP,US);
A61K48/005 (EP,US); A61K48/0083 (EP,US); A61P19/00 (EP);
A61P3/00 (EP); A61P3/04 (EP); A61K48/00 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/36]
TitleGerman:ZUSAMMENSETZUNG FÜR DIE ÄNDERUNG DER KNOCHENEIGENSCHAFTEN BEI EINEM PROBANDEN[2011/03]
English:COMPOSITION TO ALTER BONE PROPERTIES IN A SUBJECT[2011/03]
French:COMPOSITION PERMETTANT DE MODIFIER LES PROPRIETES OSSEUSES D'UN SUJET[2011/03]
Former [2004/36]ZUSAMMENSETZUNG UND VERFAHREN FÜR DIE ÄNDERUNG DER FETTFREIEN KÖRPERMASSE UND DER KNOCHENEIGENSCHAFTEN BEI EINEM PROBANDEN
Former [2004/36]A COMPOSITION AND METHOD TO ALTER LEAN BODY MASS AND BONE PROPERTIES IN A SUBJECT
Former [2004/36]COMPOSITION ET METHODE PERMETTANT DE MODIFIER LA MASSE MAIGRE ET LES PROPRIETES OSSEUSES D'UN SUJET
Entry into regional phase25.05.2004National basic fee paid 
25.05.2004Search fee paid 
25.05.2004Designation fee(s) paid 
25.05.2004Examination fee paid 
Examination procedure16.05.2003Request for preliminary examination filed
International Preliminary Examining Authority: US
25.05.2004Examination requested  [2004/36]
26.05.2004Amendment by applicant (claims and/or description)
13.09.2007Despatch of a communication from the examining division (Time limit: M06)
20.03.2008Reply to a communication from the examining division
09.10.2009Despatch of a communication from the examining division (Time limit: M06)
16.04.2010Reply to a communication from the examining division
10.03.2011Communication of intention to grant the patent
05.07.2011Fee for grant paid
05.07.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  13.09.2007
Opposition(s)10.09.2012No opposition filed within time limit [2012/46]
Fees paidRenewal fee
25.05.2004Renewal fee patent year 03
26.10.2005Renewal fee patent year 04
12.10.2006Renewal fee patent year 05
25.10.2007Renewal fee patent year 06
27.10.2008Renewal fee patent year 07
26.10.2009Renewal fee patent year 08
25.10.2010Renewal fee patent year 09
25.10.2011Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT07.12.2011
BE07.12.2011
CY07.12.2011
CZ07.12.2011
DK07.12.2011
EE07.12.2011
FI07.12.2011
IT07.12.2011
NL07.12.2011
SE07.12.2011
SK07.12.2011
TR07.12.2011
BG07.03.2012
GR08.03.2012
ES18.03.2012
PT09.04.2012
[2014/21]
Former [2013/29]AT07.12.2011
BE07.12.2011
CY07.12.2011
CZ07.12.2011
DK07.12.2011
EE07.12.2011
FI07.12.2011
IT07.12.2011
NL07.12.2011
SE07.12.2011
SK07.12.2011
BG07.03.2012
GR08.03.2012
ES18.03.2012
PT09.04.2012
Former [2013/22]AT07.12.2011
BE07.12.2011
CY07.12.2011
CZ07.12.2011
DK07.12.2011
EE07.12.2011
IT07.12.2011
NL07.12.2011
SE07.12.2011
SK07.12.2011
BG07.03.2012
GR08.03.2012
ES18.03.2012
PT09.04.2012
Former [2013/07]AT07.12.2011
BE07.12.2011
CY07.12.2011
CZ07.12.2011
DK07.12.2011
EE07.12.2011
IT07.12.2011
NL07.12.2011
SE07.12.2011
SK07.12.2011
BG07.03.2012
GR08.03.2012
PT09.04.2012
Former [2012/50]BE07.12.2011
CY07.12.2011
CZ07.12.2011
DK07.12.2011
EE07.12.2011
IT07.12.2011
NL07.12.2011
SE07.12.2011
SK07.12.2011
BG07.03.2012
GR08.03.2012
PT09.04.2012
Former [2012/49]BE07.12.2011
CY07.12.2011
CZ07.12.2011
DK07.12.2011
EE07.12.2011
NL07.12.2011
SE07.12.2011
SK07.12.2011
BG07.03.2012
GR08.03.2012
PT09.04.2012
Former [2012/37]BE07.12.2011
CY07.12.2011
CZ07.12.2011
EE07.12.2011
NL07.12.2011
SE07.12.2011
SK07.12.2011
BG07.03.2012
GR08.03.2012
PT09.04.2012
Former [2012/36]BE07.12.2011
CY07.12.2011
CZ07.12.2011
EE07.12.2011
NL07.12.2011
SE07.12.2011
SK07.12.2011
BG07.03.2012
GR08.03.2012
Former [2012/35]BE07.12.2011
CY07.12.2011
CZ07.12.2011
EE07.12.2011
NL07.12.2011
SE07.12.2011
BG07.03.2012
GR08.03.2012
Former [2012/34]BE07.12.2011
CY07.12.2011
CZ07.12.2011
NL07.12.2011
SE07.12.2011
GR08.03.2012
Former [2012/30]BE07.12.2011
CY07.12.2011
NL07.12.2011
SE07.12.2011
GR08.03.2012
Former [2012/28]CY07.12.2011
NL07.12.2011
SE07.12.2011
GR08.03.2012
Former [2012/24]NL07.12.2011
SE07.12.2011
GR08.03.2012
Documents cited:Search[A]WO9905300  (GENEMEDICINE INC [US], et al) [A] * page 79 - page 82; example 5 * * page 73, line 23 - page 74, line 6 *;
 [A]WO0106988  (BAYLOR COLLEGE MEDICINE [US], et al) [A] * page 5, line 24 - page 7, line 25 *;
 [X]WO0121801  (DAVIES PAUL R [CN], et al) [X] 1,2,5-18,21-35,42-66 * page 7, line 29 - page 9, line 31 * * page 12, line 1 - line 29 *;
 [A]WO0166149  (VALENTIS INC [US], et al) [A] 10,26,64 * claims 30,39,42 *;
 [PX]WO02061037  (BAYLOR COLLEGE MEDICINE [US], et al) [PX] 1,2,5-18,21-35,42-66 * page 7 - page 8 * * page 34, paragraph 123 * * page 42, paragraph 17; example 14 *;
 [E]WO03049700  (ADVISYS INC [US], et al) [E] 3,4,6,7,11-16* page 67 - page 68; example 8 *;
 [E]WO2004018697  (BAYLOR COLLEGE MEDICINE [US]) [E] 3-16,39-41 * claims 1-8,11,15-37,39,43-71,73,77,78 *;
 [X]  - ENRIGHT, W. J. ET AL, "Effects of growth hormone-releasing factor and(or) thyrotropin-releasing hormone on growth, feed efficiency, carcass characteristics, and blood hormones and metabolites in beef heifers", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 119:248880, URL: STN, XP002401644 [X] 36,37,39-41 * abstract *
 [X]  - MOELLERS, R. F. ET AL, "Pulsatile infusion of growth hormone-releasing factor depresses growth of young broiler chickens", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 120:266266, URL: STN, XP002401645 [X] 36,37,39-41 * abstract *
 [X]  - DRAGHIA-AKLI RUXANDRA ET AL, "Myogenic expression of an injectable protease-resistant growth hormone-releasing hormone augments long-term growth in pigs", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (199912), vol. 17, no. 12, ISSN 1087-0156, pages 1179 - 1183, XP002159711 [X] 3-16,19-35 * page 1180; figure 1 * * page 1182, paragraphs 2,3 *

DOI:   http://dx.doi.org/10.1038/70718
 [DX]  - DUBREUIL PASCAL ET AL, "Long-term growth hormone-releasing factor administration on growth hormone, insulin-like growth factor-I concentrations and bone healing in the beagle", CANADIAN JOURNAL OF VETERINARY RESEARCH, (1996), vol. 60, no. 1, ISSN 0830-9000, pages 7 - 13, XP002408693 [DX] 38-41 * page 7 * * abstract *
International search[X]WO0106988  (BAYLOR COLLEGE MEDICINE [US], et al);
 [XP]US6423693  (SCHWARTZ ROBERT J [US], et al);
 [T]US2003074679  (SCHWARTZ ROBERT J [US], et al);
 [X]  - BOHLEN ET AL., "Isolation and characterization of the porcine hypothalamic growth hormone releasing factor", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (198310), vol. 116, no. 2, pages 726 - 734, XP002966733

DOI:   http://dx.doi.org/10.1016/0006-291X(83)90585-5
 [A]  - IRANMANESH ET AL., "Unequal impact of age, percentage body fat and serum testosterone concentrations on the somatotropic, IGF-I and IGF-binding protein responses to a three-day intravenous growth hormone-releasing hormone pulsatile infusion in men", EUROPEAN JOURNAL OF ENDOCRINOLOGY, (1998), vol. 139, pages 59 - 71, XP002966734

DOI:   http://dx.doi.org/10.1530/eje.0.1390059
 [A]  - DRAGHIA-AKLI ET AL., "Myogenic expression of an injectable protease-resistant growth hormone-releasing hormone augments long-term growth in pigs", NATURE BIOTECHNOLOGY, (199912), vol. 17, pages 1179 - 1183, XP002159711

DOI:   http://dx.doi.org/10.1038/70718
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