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EP1456403
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EP About this file: EP1456403
| EP1456403 - METHODS FOR IDENTIFYING COMPOUNDS FOR TREATING CONGESTIVE HEART FAILURE USING HUMAN AMINOPEPTIDASE N [Right-click to bookmark this link] | |||
| Former [2004/38] | METHODS OF USING 48149, A HUMAN AMINOPEPTIDASE FAMILY MEMBER | ||
| [2008/07] | Status | The application is deemed to be withdrawn Status updated on 10.07.2009 Database last updated on 03.09.2024 | Most recent event Tooltip | 10.07.2009 | Application deemed to be withdrawn | published on 12.08.2009 [2009/33] | Applicant(s) | For all designated states MILLENNIUM PHARMACEUTICALS, INC. 75 Sidney Street Cambridge Massachusetts 02139 / US | [N/P] |
| Former [2004/38] | For all designated states Millennium Pharmaceuticals, Inc. 75 Sidney Street Cambridge, Massachusetts 02139 / US | Inventor(s) | 01 /
CHUN, Miyoung 88 Country Club Lane Belmont, MA 02478 / US | [2004/38] | Representative(s) | Spaltmann, Frank, et al Bayer HealthCare AG 51368 Leverkusen / DE | [N/P] |
| Former [2006/29] | Spaltmann, Frank, et al Bayer HealthCare AG 51368 Leverkusen / DE | ||
| Former [2004/38] | Harrison Goddard Foote Fountain Precinct, Balm Green Sheffield S1 2JA / GB | Application number, filing date | 02793843.0 | 29.10.2002 | [2004/38] | WO2002US34622 | Priority number, date | US20010335084P | 31.10.2001 Original published format: US 335084 P | [2004/38] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO03042358 | Date: | 22.05.2003 | Language: | EN | [2003/21] | Type: | A2 Application without search report | No.: | EP1456403 | Date: | 15.09.2004 | Language: | EN | The application published by WIPO in one of the EPO official languages on 22.05.2003 takes the place of the publication of the European patent application. | [2004/38] | Search report(s) | International search report - published on: | US | 08.07.2004 | (Supplementary) European search report - dispatched on: | EP | 31.10.2005 | Classification | IPC: | G01N33/573, C12N9/48, A61K38/48, A61K38/55, A61K39/395, A61K31/7088, A61P9/10, C12Q1/37, C12Q1/68 | [2005/13] | CPC: |
C12N9/48 (EP,US);
A61P11/00 (EP);
A61P11/06 (EP);
A61P13/12 (EP);
A61P3/06 (EP);
A61P35/00 (EP);
A61P7/02 (EP);
A61P9/00 (EP);
A61P9/04 (EP);
|
| Former IPC [2004/38] | C12Q1/37, C12Q1/68, C12N9/48 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, SK, TR [2004/38] | Extension states | AL | Not yet paid | LT | Not yet paid | LV | Not yet paid | MK | Not yet paid | RO | Not yet paid | SI | Not yet paid | Title | German: | VERFAHREN ZUR IDENTIFIZIERUNG VON VERBINDUNGEN ZUR BEHANDLUNG DES KONGESTIVEN HERZVERSAGEN UNTER VERWENDUNG VON MENSCHLICHEN AMINOPEPTIDASE N | [2008/07] | English: | METHODS FOR IDENTIFYING COMPOUNDS FOR TREATING CONGESTIVE HEART FAILURE USING HUMAN AMINOPEPTIDASE N | [2008/07] | French: | METHODES POUR L'IDENTIFICATION DE COMPOSES POUR LE TRAITEMENT DE L'INSUFFISANCE CARDIAQUE CONGESTIVE EN UTILISANT L'AMINOPEPTIDASE N HUMAINE | [2008/07] |
| Former [2004/38] | VERFAHREN ZUR VERWENDUNG VON 48149, EINEM MITGLIED DER MENSCHLICHEN AMINOPEPTIDASE-FAMILIE | ||
| Former [2004/38] | METHODS OF USING 48149, A HUMAN AMINOPEPTIDASE FAMILY MEMBER | ||
| Former [2004/38] | METHODES D'UTILISATION DE 48149, UN ELEMENT DE LA FAMILLE DE L'AMINOPEPTIDASE HUMAINE | Entry into regional phase | 09.03.2004 | National basic fee paid | 09.03.2004 | Search fee paid | 09.03.2004 | Designation fee(s) paid | 09.03.2004 | Examination fee paid | Examination procedure | 09.03.2004 | Amendment by applicant (claims and/or description) | 09.03.2004 | Examination requested [2004/38] | 16.05.2006 | Despatch of a communication from the examining division (Time limit: M06) | 13.11.2006 | Reply to a communication from the examining division | 27.11.2007 | Date of oral proceedings | 22.01.2008 | Minutes of oral proceedings despatched | 10.10.2008 | Communication of intention to grant the patent | 21.02.2009 | Application deemed to be withdrawn, date of legal effect [2009/33] | 27.03.2009 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2009/33] | Fees paid | Renewal fee | 25.10.2004 | Renewal fee patent year 03 | 27.10.2005 | Renewal fee patent year 04 | 31.10.2006 | Renewal fee patent year 05 | 31.10.2007 | Renewal fee patent year 06 | 22.03.2008 | Renewal fee patent year 07 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [PX]WO02053170 (INST MEDIZINTECHNOLOGIE MAGDEB [DE], et al) [PX] 1,7-9,11 * claim - *; | [PX]DE10100052 (INST MEDIZINTECHNOLOGIE MAGDEB [DE]) [PX] 1,7-9,11* the whole document *; | [E]WO03006646 (BAYER AG [DE], et al) [E] 1,7-9,11 * the whole document *; | [T]EP1346729 (CARDIOVASCULAR RES INST MAASTR [NL], et al) [T] 1,7-9,11 * the whole document *; | [X] - LOJDA Z, "THE IMPORTANCE OF PROTEASE HISTOCHEMISTRY IN PATHOLOGY", HISTOCHEMICAL JOURNAL, (1985), vol. 17, no. 10, ISSN 0018-2214, pages 1063 - 1090, XP008042272 [X] 1,7-9,11 * page 1064, paragraph 2; tables 1,2 * * page 1067, paragraph 5 - page 1068, paragraph 2 * * page 1081, paragraph 3 - page 1082, paragraph 1; figure 4 * DOI: http://dx.doi.org/10.1007/BF01002534 | [X] - PASQUALINI RENATA ET AL, "Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, (20000201), vol. 60, no. 3, ISSN 0008-5472, pages 722 - 727, XP002180667 [X] 1,7-9,11 * the whole document * | [X] - JOHNSON JASON L ET AL, "Activation of matrix-degrading metalloproteinases by mast cell proteases in atherosclerotic plaques", ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, (199811), vol. 18, no. 11, ISSN 1079-5642, pages 1707 - 1715, XP002315869 [X] 1,7-9,11 * the whole document * | [A] - SHIMAZAWA R ET AL, "NOVEL SMALL MOLECULE NONPEPTIDE AMINOPEPTIDASE N INHIBITORS WITH A CYCLIC IMIDE SKELETON", JOURNAL OF ENZYME INHIBITION, NEW YORK, NY, US, (1999), vol. 14, no. 4, pages 259 - 275, XP001018772 [A] * the whole document * | [A] - NUNEZ LILIANA ET AL, "Cholesterol crystallization-promoting activity of aminopeptidase N isolated from the vesicular carrier of biliary lipids", FEBS (FEDERATION OF EUROPEAN BIOCHEMICAL SOCIETIES) LETTERS, (1993), vol. 329, no. 1-2, ISSN 0014-5793, pages 84 - 88, XP002315840 [A] * the whole document * DOI: http://dx.doi.org/10.1016/0014-5793(93)80199-5 | [A] - LENDECKEL U ET AL, "Role of Alanyl Aminopeptidase in Growth and Function of Human T Cells", INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS, ATHENS, GR, (1999), vol. 4, ISSN 1107-3756, pages 17 - 27, XP002977300 [A] 1,7-9,11 * the whole document * | International search | [Y] - PASQUALINI, R ET AL., "Aminopeptidase N is a Receptor for Tumor-Homing Peptides and a Target for Inhibiting Angiogenesis", CANCER RESEARCH, (20000201), vol. 60, pages 722 - 727, XP002180667 | [A] - LENDECKEL, U. ET AL., "Role of Alanyl Aminopeptidase in Growth and Function of Human T Cells", INT. J. MOLECULAR MEDICINE, (1999), vol. 4, pages 17 - 27, XP002977300 | [A] - RIEMANN, D. ET AL., "CD-13- Not Just a Marker in Leukemia Typing", IMMUNOLOGY TODAY, (199902), vol. 20, no. 2, pages 83 - 88, XP004157281 DOI: http://dx.doi.org/10.1016/S0167-5699(98)01398-X | [Y] - SAIKI, I. ET AL., "Role of Aminopeptidase N (CD13) in Tumor-Cell Invasion and Extracellular Matrix Degradation", INT. J. CANCER, (1993), vol. 54, pages 137 - 143, XP002977601 DOI: http://dx.doi.org/10.1002/ijc.2910540122 | [Y] - FUJII, H. ET AL., "Human Melanoma Invasion and Metastasis Enhancement by High Expression of Aminopeptidase N/CD13", CLIN. EXP. METASTASIS, (1995), vol. 13, pages 337 - 344, XP002977602 DOI: http://dx.doi.org/10.1007/BF00121910 | Examination | WO02053170 |