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Extract from the Register of European Patents

EP About this file: EP1446007

EP1446007 - METHODS AND COMPOSITIONS FOR TARGETING UNDERGLYCOSYLATED PROTEINS ACROSS THE BLOOD BRAIN BARRIER [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  22.06.2012
Database last updated on 12.06.2024
Most recent event   Tooltip22.06.2012Application deemed to be withdrawnpublished on 25.07.2012  [2012/30]
Applicant(s)For all designated states
BioMarin Pharmaceutical Inc.
105 Digital Drive
Novato, CA 94949 / US
[N/P]
Former [2011/20]For all designated states
BioMarin Pharmaceutical Inc.
105 Digital Drive
Novato, CA 94949 / US
Former [2005/11]For all designated states
ZyStor Therapeutics, Inc.
770 North Water Street
Milwaukee, Wisconsin, 53202 / US
Former [2004/34]For all designated states
Symbiontics, Inc.
4041 Forest Park Avenue
St. Louis, MO 63108-2211 / US
Inventor(s)01 / Dr Jonathan LeBowitz
6128 North Kent Avenue
Whitefish Bay, WI 53217 / US
02 / SLY, Wilian, S.
7054 Westmoreland Drive
St. Louis, MO 63130 / US
 [2006/25]
Former [2006/23]01 / LEBOWITZ, Jonathan, H.
6128 North Kent Avenue
Whitefish Bay, WI 53217 / US
02 / SLY, Wilian, S.
7054 Westmoreland Drive
St. Louis, MO 63130 / US
Former [2004/34]01 / LEBOWITZ, Jonathan, H.
1 Devondale Lane
St. Louis, MO 63131 / US
02 / SLY, Wilian, S.
7054 Westmoreland Drive
St. Louis, MO 63130 / US
Representative(s)Chapman, Paul William
Kilburn & Strode LLP
20 Red Lion Street
London
WC1R 4PJ / GB
[N/P]
Former [2004/34]Chapman, Paul William
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date02801739.016.10.2002
[2004/34]
WO2002US32968
Priority number, dateUS20010329650P16.10.2001         Original published format: US 329650 P
US2002013684130.04.2002         Original published format: US 136841
US2002013663930.04.2002         Original published format: US 136639
US20020384452P29.05.2002         Original published format: US 384452 P
US20020386019P05.06.2002         Original published format: US 386019 P
US20020408816P06.09.2002         Original published format: US 408816 P
[2004/34]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03032727
Date:24.04.2003
Language:EN
[2003/17]
Type: A1 Application with search report 
No.:EP1446007
Date:18.08.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 24.04.2003 takes the place of the publication of the European patent application.
[2004/34]
Search report(s)International search report - published on:US24.04.2003
(Supplementary) European search report - dispatched on:EP24.10.2005
ClassificationIPC:A01N37/18, A61K38/00, C12P21/06, C12N5/00, C12N5/02, C12N15/74, C07K1/00, C07K14/00, C07K16/00, C07K17/00, C07H21/04
[2004/34]
CPC:
C12N15/62 (EP); A61K38/30 (EP); A61K47/642 (EP);
A61K47/6425 (EP); A61P13/12 (EP); A61P25/00 (EP);
A61P9/10 (EP); C07K14/65 (EP); C07K2319/00 (EP);
C07K2319/02 (EP); C07K2319/06 (EP); C07K2319/21 (EP);
C07K2319/50 (EP); C07K2319/61 (EP); C07K2319/74 (EP);
C07K2319/75 (EP) (-)
C-Set:
A61K38/30, A61K2300/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/34]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNG FÜR DIE ZIELSTEUERUNG VON HYPOGLYCOSYLIERTEN PROTEINEN ÜBER DIE BLUT-HIRN-BARRIERE[2004/34]
English:METHODS AND COMPOSITIONS FOR TARGETING UNDERGLYCOSYLATED PROTEINS ACROSS THE BLOOD BRAIN BARRIER[2004/34]
French:TECHNIQUES ET COMPOSITIONS PERMETTANT LE CIBLAGE DE PROTEINES SOUS-GLYCOSYLEES A TRAVERS LA BARRIERE HEMATO-ENCEPHALIQUE[2004/34]
Entry into regional phase14.05.2004National basic fee paid 
14.05.2004Search fee paid 
14.05.2004Designation fee(s) paid 
14.05.2004Examination fee paid 
Examination procedure13.05.2004Amendment by applicant (claims and/or description)
14.05.2004Examination requested  [2004/34]
22.03.2006Despatch of a communication from the examining division (Time limit: M08)
14.03.2007Reply to a communication from the examining division
23.04.2007Despatch of a communication from the examining division (Time limit: M08)
17.04.2008Reply to a communication from the examining division
05.11.2008Despatch of a communication from the examining division (Time limit: M08)
21.10.2009Reply to a communication from the examining division
25.06.2010Despatch of a communication from the examining division (Time limit: M06)
24.12.2010Reply to a communication from the examining division
01.09.2011Despatch of a communication from the examining division (Time limit: M04)
12.01.2012Application deemed to be withdrawn, date of legal effect  [2012/30]
28.02.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2012/30]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.03.2006
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
18.04.2008Request for further processing filed
18.04.2008Full payment received (date of receipt of payment)
Request granted
26.05.2008Decision despatched
14.03.2007Request for further processing filed
15.03.2007Full payment received (date of receipt of payment)
Request granted
29.03.2007Decision despatched
Fees paidRenewal fee
25.10.2004Renewal fee patent year 03
27.10.2005Renewal fee patent year 04
27.10.2006Renewal fee patent year 05
29.10.2007Renewal fee patent year 06
27.10.2008Renewal fee patent year 07
26.10.2009Renewal fee patent year 08
25.10.2010Renewal fee patent year 09
25.10.2011Renewal fee patent year 10
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Documents cited:Search[X]WO9104014  (SYNERGEN INC [US]) [X] 1 * page 5, paragraph 2; claims 1,2 *;
 [X]WO9502421  (ALKERMES INC [US], et al) [X] 1-30 * page 10, line 12 - line 29; claims 1-3,6 *;
 [E]WO02087510  (SYMBIONTICS INC [US]) [E] 1* claims 1-52 *;
 [E]WO03032913  (SYMBIONTICS INC [US], et al) [E] 1 * claims 1-20 *;
 [E]WO03102583  (SYMBIONTICS INC [US], et al) [E] 1 * claims 1,10,11 *
International search[Y]US6472140  (TANZI RUDOLPH E [US], et al);
 [Y]  - KIM S-O, "High-level expression and simple purification of recombinant human insulin-like growth factor I", JOURNAL OF BIOTECHNOLOGY, (199602), vol. 48, pages 97 - 105, XP002169455

DOI:   http://dx.doi.org/10.1016/0168-1656(96)01402-2
Examination   - DUFFY K R ET AL, "Human blood-brain barrier insulin-like growth factor receptor", METABOLISM, CLINICAL AND EXPERIMENTAL, W.B. SAUNDERS CO., PHILADELPHIA, PA, US, vol. 37, no. 2, ISSN 0026-0495, (19880201), pages 136 - 140, (19880201), XP026359542
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.