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Extract from the Register of European Patents

EP About this file: EP1471068

EP1471068 - PROCESS FOR TOTAL SYNTHESIS OF ECTEINASCIDINS AND INTERMEDIATES THEREFOR [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  02.06.2006
Database last updated on 07.10.2024
Most recent event   Tooltip02.06.2006Withdrawal of applicationpublished on 05.07.2006  [2006/27]
Applicant(s)For all designated states
Japan Science and Technology Agency
1-8, Honcho 4-chome Kawaguchi-shi
Saitama 332-0012 / JP
[N/P]
Former [2004/44]For all designated states
Japan Science and Technology Agency
1-8, Honcho 4-chome
Kawaguchi-shi, Saitama 332-0012 / JP
Inventor(s)01 / FUKUYAMA, Tohru
1-3-17-906, Etchujima
Koto-ku, Tokyo 135-0044 / JP
02 / KAN, Toshiyuki
2-11-2-1002, Nedu
Bunkyo-ku, Tokyo 113-0031 / JP
 [2004/44]
Representative(s)McCluskie, Gail Wilson, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2004/44]McCluskie, Gail Wilson, et al
J.A. Kemp & Co., 14 South Square, Gray's Inn
London WC1R 5JJ / GB
Application number, filing date02806664.520.09.2002
[2004/44]
WO2002JP09690
Priority number, dateJP2002001936029.01.2002         Original published format: JP 2002019360
[2004/44]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03064432
Date:07.08.2003
Language:EN
[2003/32]
Type: A1 Application with search report 
No.:EP1471068
Date:27.10.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 07.08.2003 takes the place of the publication of the European patent application.
[2004/44]
Search report(s)International search report - published on:JP07.08.2003
(Supplementary) European search report - dispatched on:EP23.02.2005
ClassificationIPC:C07D515/22, C07D513/22, C07D491/22, C07D471/08, C07D317/64, C07C271/22, C07C269/06, C07D493/22
[2005/14]
CPC:
C07D471/08 (EP,US); C07C271/22 (EP,US); C07D317/64 (EP,US);
C07D405/06 (EP,US); C07D413/04 (EP,US); Y02P20/55 (EP,US)
Former IPC [2004/44]C07D515/22, C07D513/22, C07D491/22, C07D471/08, C07D317/64, C07C271/22, C07C269/06
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/44]
TitleGerman:VERFAHREN ZUR TOTALSYNTHESE VON ECTEINASCIDINEN UND ZWISCHENPRODUKTE DAFÜR[2004/44]
English:PROCESS FOR TOTAL SYNTHESIS OF ECTEINASCIDINS AND INTERMEDIATES THEREFOR[2004/44]
French:PROCEDE DE SYNTHESE TOTALE D'ECTEINASCIDINES ET INTERMEDIAIRES UTILISES DANS CE PROCEDE[2004/44]
Entry into regional phase23.07.2004Translation filed 
23.07.2004National basic fee paid 
23.07.2004Search fee paid 
23.07.2004Designation fee(s) paid 
23.07.2004Examination fee paid 
Examination procedure23.07.2004Examination requested  [2004/44]
11.10.2004Amendment by applicant (claims and/or description)
23.05.2006Application withdrawn by applicant  [2006/27]
Fees paidRenewal fee
23.07.2004Renewal fee patent year 03
14.09.2005Renewal fee patent year 04
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]WO9812198  (HARVARD COLLEGE [US]) [Y] 1-14 * page 52; example 33 *;
 [XA]WO0153299  (UNIV COLUMBIA [US]) [X] 9 * figure 9B; page 15/22 * * the whole document *[A] 1-14;
 [Y]WO0177115  (PHARMA MAR SA [ES], et al) [Y] 1-14 * page 107 - page 110; examples 32-35 *;
 [YP]  - ENDO ATSUSHI ET AL, "Total synthesis of ecteinascidin 743", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, (20020517), vol. 124, no. 23, ISSN 0002-7863, pages 6552 - 6554, XP002961311 [YP] 1-14 * examples 15,21,26,29 *

DOI:   http://dx.doi.org/10.1021/ja026216d
 [YP]  - ZHOU ET AL, "Studies Directed to the Total Synthesis of ET 743 and Analogues Thereof: An Expeditious Route to the ABFGH Subunit", ORGANIC LETTERS, ACS, WASHINGTON, DC, US, (2002), vol. 4, no. 1, ISSN 1523-7060, pages 43 - 46, XP002224122 [YP] 1-14 * scheme 1, compounds 6, 7 *

DOI:   http://dx.doi.org/10.1021/ol016844k
 [Y]  - CUEVAS C ET AL, "SYNTHESIS OF ECTEINASCIDIN ET-743 AND PHTHALASCIDIN PT-650 FROM CYANOSAFRACIN B", ORGANIC LETTERS, ACS, WASHINGTON, DC, US, (2000), vol. 2, no. 16, ISSN 1523-7060, pages 2454 - 2458, XP002940454 [Y] 1-14 * scheme 1, compounds 12,13 *

DOI:   http://dx.doi.org/10.1021/ol0062502
 [Y]  - COREY E J ET AL, "ENANTIOSELECTIVE TOTAL SYNTHESIS OF ECTEINASCIDIN 743", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, (1996), vol. 118, ISSN 0002-7863, pages 9202 - 9203, XP000941402 [Y] 1-14 * scheme 1, compounds 13, 14 *

DOI:   http://dx.doi.org/10.1021/ja962480t
International search[A]WO9812198  (HARVARD COLLEGE [US]);
 [A]WO0153299  (UNIV COLUMBIA [US]);
 [A]WO0177115  (PHARMA MAR SA [ES], et al);
 [A]  - COREY E.J. ET AL., "Enantioselective total synthesis of ecteinascidin 743", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1996), vol. 118, no. 38, pages 9202 - 9203, XP000941402

DOI:   http://dx.doi.org/10.1021/ja962480t
 [A]  - HINTERDING KLAUS ET AL., "Synthesis and in vitro evaluation of the ras farnesyltransferase inhibitor pepticinnamin E", ANGEWANDTE CHEMIE, INTERNATIONAL EDITION, (1998), vol. 37, no. 9, pages 1236 - 1239, XP002985182

DOI:   http://dx.doi.org/10.1002/(SICI)1521-3773(19980518)37:9<1236::AID-ANIE1236>3.0.CO;2-F
 [XP]  - ENDO ATSUSHI ET AL., "Total synthesis of ecteinascidin 743", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (20020517), vol. 124, no. 23, pages 6552 - 6654, XP002961311

DOI:   http://dx.doi.org/10.1021/ja026216d
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.