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Extract from the Register of European Patents

EP About this file: EP1306088

EP1306088 - Combination of a benzimidazole having angiotensin-II antagonistic activity with a diuretic [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.07.2008
Database last updated on 02.09.2024
Most recent event   Tooltip25.07.2008Lapse of the patent in a contracting state
New state(s): DK		published on 27.08.2008  [2008/35]
Applicant(s)For all designated states
Takeda Pharmaceutical Company Limited
1-1, Doshomachi 4-chome, Chuo-ku
Osaka / JP
[2005/14]
Former [2003/18]For all designated states
Takeda Chemical Industries, Ltd.
1-1 Doshomachi 4-chome, Chuo-ku
Osaka-shi, Osaka 541-0045 / JP
Inventor(s)01 / Inada, Yoshiyuki
3-6, Matsugaoka-cho
Kawanishi, Hyogo 666 / JP
02 / Kubo, Keiji
12-25-202, Hancho 4-chome
Minoo, Osaka 562 / JP
 [2003/18]
Representative(s)Teipel, Stephan, et al
Lederer & Keller
Patentanwälte Partnerschaft mbB
Unsöldstrasse 2
80538 München / DE
[N/P]
Former [2003/18]Teipel, Stephan, Dr., et al
Lederer & Keller Patentanwälte Prinzregentenstrasse 16
80538 München / DE
Application number, filing date03001569.707.06.1994
[2003/18]
Priority number, dateJP1993013552407.06.1993         Original published format: JP 13552493
[2003/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1306088
Date:02.05.2003
Language:EN
[2003/18]
Type: B1 Patent specification 
No.:EP1306088
Date:05.09.2007
Language:EN
[2007/36]
Search report(s)(Supplementary) European search report - dispatched on:EP12.03.2003
ClassificationIPC:A61K31/4184, A61K31/635, A61P9/12, A61P9/04, A61P9/10, A61P13/12, A61P5/42, A61P17/00, A61P25/28, A61P25/24, A61P25/22, A61P25/18, A61P27/06
[2007/14]
CPC:
A61K31/495 (EP); A61K31/341 (EP); A61K31/41 (EP);
A61K31/415 (EP); A61K31/4184 (EP); A61K31/4245 (EP);
A61K31/496 (EP); A61K31/5415 (EP); A61K45/06 (EP);
A61P13/12 (EP); A61P17/00 (EP); A61P25/00 (EP);
A61P25/18 (EP); A61P25/22 (EP); A61P25/24 (EP);
A61P25/28 (EP); A61P27/06 (EP); A61P5/00 (EP);
A61P5/42 (EP); A61P9/00 (EP); A61P9/04 (EP);
A61P9/10 (EP); A61P9/12 (EP) (-)
C-Set:
A61K31/341, A61K2300/00 (EP);
A61K31/4184, A61K2300/00 (EP);
A61K31/4245, A61K2300/00 (EP);
A61K31/495, A61K2300/00 (EP);
A61K31/496, A61K2300/00 (EP);
A61K31/5415, A61K2300/00 (EP)
(-)
Former IPC [2003/18]A61K31/63, A61K31/44, A61K31/54, A61K31/415, // (A61K31/415, 31:63, 31:54, 31:44)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [2003/18]
TitleGerman:Kombination eines Angiotensin-II antagonistisch wirkenden Benzimidazols mit einem Diuretikum[2003/18]
English:Combination of a benzimidazole having angiotensin-II antagonistic activity with a diuretic[2003/18]
French:Combinaison d'un benzimidazole ayant une activité antagoniste de l'angiotensine-II avec un diurétique[2003/18]
Examination procedure03.11.2003Examination requested  [2004/01]
19.11.2004Despatch of a communication from the examining division (Time limit: M08)
21.07.2005Reply to a communication from the examining division
17.08.2005Despatch of a communication from the examining division (Time limit: M06)
10.02.2006Reply to a communication from the examining division
08.05.2006Despatch of a communication from the examining division (Time limit: M06)
17.11.2006Reply to a communication from the examining division
12.03.2007Communication of intention to grant the patent
10.07.2007Fee for grant paid
10.07.2007Fee for publishing/printing paid
Parent application(s)   TooltipEP94108687.8  / EP0628313
EP96115146.1  / EP0753301
Opposition(s)06.06.2008No opposition filed within time limit [2008/33]
Fees paidRenewal fee
23.01.2003Renewal fee patent year 03
23.01.2003Renewal fee patent year 04
23.01.2003Renewal fee patent year 05
23.01.2003Renewal fee patent year 06
23.01.2003Renewal fee patent year 07
23.01.2003Renewal fee patent year 08
23.01.2003Renewal fee patent year 09
23.01.2003Renewal fee patent year 10
27.05.2004Renewal fee patent year 11
31.05.2005Renewal fee patent year 12
31.03.2006Renewal fee patent year 13
30.05.2007Renewal fee patent year 14
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT05.09.2007
BE05.09.2007
DK05.09.2007
NL05.09.2007
SE05.12.2007
GR06.12.2007
ES16.12.2007
PT06.02.2008
[2008/35]
Former [2008/28]AT05.09.2007
BE05.09.2007
NL05.09.2007
SE05.12.2007
GR06.12.2007
ES16.12.2007
PT06.02.2008
Former [2008/24]AT05.09.2007
BE05.09.2007
NL05.09.2007
GR06.12.2007
ES16.12.2007
PT06.02.2008
Former [2008/21]AT05.09.2007
BE05.09.2007
GR06.12.2007
ES16.12.2007
Former [2008/13]AT05.09.2007
ES16.12.2007
Former [2008/08]ES16.12.2007
Documents cited:Search[X]EP0400835  (MERCK & CO INC [US]) [X] 1-20 * page 1 - page 11, line 15 * * page 26, lines 21-49 * * page 37, lines 40-42; claim -; table I *;
 [D]JPH0327362  (MERCK & CO INC);
 [DY]EP0459136  (TAKEDA CHEMICAL INDUSTRIES LTD [JP]) [DY] 1-20 * claim - *;
 [Y]EP0501892  (SANOFI ELF [FR]) [Y] 1-20 * page 9, lines 28-30; claim - *;
 [D]JPH05132467  (SANOFI ELF);
 [PY]GB2270841  (MERCK & CO INC [US]) [PY] 1-20 * the whole document, especially page 4, compound IX *;
 [Y]  - K. KINUGAWA, "Effects of a nonpeptide angiotensin II receptor antagonist (CV-11974) on [Ca2+]i and cell motion in cultured ventricular myocites.", EUR. J. PHARMACOL., (199304), vol. 235, no. 2-3, pages 313- - 316, XP008014593 [Y] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1016/0014-2999(93)90153-9
 [T]  - T.WADA ET AL., "Combined Effects of the Angiotensin II Antagonist Candesartan Cilexetil (TCV-116) and Other Classes of Antihypertensive Drugs in Spontaneously Hypertensive Rats", HYPERTENS. RES., (199612), vol. 19, no. 4, pages 247 - 254, XP001031392 [T] 1-20 * the whole document *
 [A]  - T. NAGAO ET AL., "Calcium Entry Blockers: Antihypertensive and Natriuretic Effects in Experimental Animals", AM. J. CARDIOL., (19851206), vol. 56, no. 16, pages 56H - 61H, XP008014594 [A] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1016/0002-9149(85)90545-4
 [XP]  - Y. INADA ET AL., "Antihypertensive Effects of a Highly Potent and long-Acting Angiotensin II Subtype-1 Receptor Antagonist. (+-)-1-(Cyclohexyloxycarbonyloxy)ethyl w2-Ethoxy-1-[[2'-(1H-Tetrazol-5-yl)Biphenyl-4-yl]Methyl]-1H-Benzimidazole-7-Carboxylate (TCV-116), in Various Hypertensive Rats", J. PHARM. EXP THER., (199403), vol. 268, no. 3, pages 1540 - 1547, XP008014592 [XP] 1-20 * the whole document *
 [T]  - K. SATO ET AL., "ROLE OF ANGIOTENSIN II IN REFLEX TACHYCARDIA DURING HYPOTENSION CAUSED BY A CALCIUM CHANNEL BLOCKER", CLIN. AND EXPER. HYPERTENSION, (199607), vol. 18, no. 5, pages 607 - 624, XP001031405 [T] 1-20 * the whole document *
 [A]  - P SLEIGHT, "Cardiac Benefits of ACE Inhibitors and Calcium Antagonists Alone and in Combination", J. CARDIOVASC. PHARMACOL., (1994), vol. 23, no. Suppl. 1, pages S39 - S42, XP001031381 [A] 1-20 * abstract *
ExaminationEP0461039
 WO9210097
 EP0520423
 EP0533058
 EP0546358
 WO9409778
    - FUMIHIKO OKADA, "Depression after treatment with thiazide diuretics for hypertension", AM. J. PSYCHIATRY, (1985), vol. 142, no. 9, pages 1101 - 1102, XP008037312
    - GRIFFING G. T. ET AL., "Reversal of diuretic-induced secondary hyperaldosteronism and hypeokalemia by Enalapril: a new angiotensin-converting enzyme inhibitor", METABOLISM, (1983), vol. 32, no. 7, pages 711 - 716, XP008037313
    - PECZON J. D. ET AL., "Diuretic drugs in glaucoma", AM. J. OPHTHALM., (1968), vol. 66, no. 4, pages 680 - 683, XP002067602
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.