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EP1420030
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EP About this file: EP1420030
| EP1420030 - Method for synthesis of (2S,3aS,7aS)-1-(S)-alanyl-octahydro-1H-indole-2- carboxylic acid derivatives and use in the synthesis of perindopril [Right-click to bookmark this link] | |||
| Former [2004/21] | Method for synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid derivatives and use in the synthesis of perindopril | ||
| [2004/22] | Status | The application is deemed to be withdrawn Status updated on 21.09.2007 Database last updated on 26.07.2024 | Most recent event Tooltip | 12.10.2007 | Change - French title | published on 14.11.2007 [2007/46] | Applicant(s) | For all designated states Les Laboratoires Servier 12, Place de La Défense 92415 Courbevoie Cedex / FR | [2004/21] | Inventor(s) | 01 /
Dubuffet, Thierry 17, allée des Charmilles 76190 Autretot / FR | 02 /
Lecouve, Jean-Pierre 93, rue du Docteur Vigné 76600 Le Havre / FR | [2004/21] | Application number, filing date | 03293085.1 | 10.12.2003 | [2004/21] | Filing language | FR | Procedural language | FR | Publication | Type: | A2 Application without search report | No.: | EP1420030 | Date: | 19.05.2004 | Language: | FR | [2004/21] | Type: | A3 Search report | No.: | EP1420030 | Date: | 26.05.2004 | [2004/22] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 14.04.2004 | Classification | IPC: | C07K5/06 | [2004/21] | CPC: |
C07K5/06026 (EP,US);
C07K5/06 (KR);
A61P9/00 (EP);
C07K5/00 (KR);
Y02P20/55 (EP,US)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PT, RO, SE, SI, SK, TR [2004/21] | Extension states | AL | 10.12.2003 | LT | 10.12.2003 | LV | 10.12.2003 | MK | 10.12.2003 | Title | German: | Verfahren zur Synthese von (2S,3aS,7aS)-1-(S)-Alanyl-octahydro-1H-2-carbonsäurederivaten und Verwendung in der Synthese von Perindopril | [2004/22] | English: | Method for synthesis of (2S,3aS,7aS)-1-(S)-alanyl-octahydro-1H-indole-2- carboxylic acid derivatives and use in the synthesis of perindopril | [2004/22] | French: | Procédé de synthèse de dérivés de l'acide (2S, 3aS, 7aS) - 1 - (S)-alanyl -octahydro-1H-indole-2-carboxylique et application à la synthèse du perindopril | [2007/46] |
| Former [2004/21] | Verfahren zur Synthese von (2S,3aS,7aS)-1-[(S)-Alanyl]-octohydro-1H-2-carbonsäurederivaten und Verwendung in der Synthese von Perindopril | ||
| Former [2004/21] | Method for synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid derivatives and use in the synthesis of perindopril | ||
| Former [2004/21] | Procédé de synthèse de dérivés de l'acide (2S, 3aS, 7aS) - 1 - [(S)-alanyl]-octahydro-1H-indole-2-carboxylique et application à la synthèse du perindorpil | Examination procedure | 10.12.2003 | Examination requested [2004/21] | 10.05.2005 | Despatch of a communication from the examining division (Time limit: M06) | 02.11.2005 | Reply to a communication from the examining division | 03.08.2006 | Despatch of a communication from the examining division (Time limit: M08) | 14.04.2007 | Application deemed to be withdrawn, date of legal effect [2007/43] | 30.05.2007 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2007/43] | Fees paid | Renewal fee | 28.11.2005 | Renewal fee patent year 03 | 05.12.2006 | Renewal fee patent year 04 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [Y]EP1256590 (SERVIER S A LAB [FR]) [Y] 1-6 * the whole document *; | [Y] - LI, PENG ET AL, "New and highly efficient immonium-type peptide coupling reagents: synthesis, mechanism, and application", TETRAHEDRON (2000), 56(26), 4437-4445, XP004202135 [Y] 1-6 * the whole document * DOI: http://dx.doi.org/10.1016/S0040-4020(00)00365-3 | [Y] - LI, PENG ET AL, "BOMI - a novel peptide coupling reagent", TETRAHEDRON LETTERS (1999), 40(18), 3605-3608, XP004162348 [Y] 1-6 * page 3607; table 2 * DOI: http://dx.doi.org/10.1016/S0040-4039(99)00536-5 | [Y] - LI P ET AL, "THE DEVELOPMENT OF HIGHLY EFFICIENT ONIUM-TYPE PEPTIDE COUPLING REAGENTS BASED UPON RATIONAL MOLECULAR DESIGN", JOURNAL OF PEPTIDE RESEARCH, MUNKSGAARD INTERNATIONAL PUBLISHERS, COPENHAGEN, DK, (20010801), vol. 58, no. 2, ISSN 1397-002X, pages 129 - 139, XP001039108 [Y] 1-6 * the whole document * DOI: http://dx.doi.org/10.1034/j.1399-3011.2001.00867.x | [Y] - COSTE, JACQUES ET AL, "Oxybenzotriazole free peptide coupling reagents for N-methylate amino acids", TETRAHEDRON LETTERS (1991), 32(17), 1967-70, XP001180312 [Y] 1-6 * the whole document * DOI: http://dx.doi.org/10.1016/0040-4039(91)85015-W | [Y] - CHEN, SHAOQING ET AL, "A new coupling reagent for peptide synthesis. Benzotriazolyloxybis(pyrrolidino)carbonium hexafluorophosphate (BBC)", TETRAHEDRON LETTERS (1992), 33(5), 647-50, XP001180313 [Y] 1-6 * the whole document * DOI: http://dx.doi.org/10.1016/S0040-4039(00)92333-5 | [Y] - CARPINO, LOUIS A. ET AL, "Effect of Tertiary Bases on O-Benzotriazolyluronium Salt-Induced Peptide Segment Coupling", JOURNAL OF ORGANIC CHEMISTRY (1994), 59(4), 695-8, XP002273951 [Y] 1-6 * the whole document * DOI: http://dx.doi.org/10.1021/jo00083a001 |