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Extract from the Register of European Patents

EP About this file: EP1470121

EP1470121 - PYRIMIDINE DERIVATIVES AS RHO-KINASE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  17.05.2013
Database last updated on 05.10.2024
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): HU, LU
published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
Bayer HealthCare LLC
555 White Plains Road
Tarrytown, NY 10591 / US
[2010/31]
Former [2004/44]For all designated states
Bayer Pharmaceuticals Corporation
400 Morgan Lane
West Haven, CT 06516 / US
Inventor(s)01 / NAGARATHNAM, Dhanapalan
52 Virginia Drive
Bethany, CT 06524 / US
02 / DUMAS, Jacques
98 Farmview Road
Bethany, CT 06524 / US
03 / HATOUM-MOKDAD, Holia
43 Joseph Lane
Hamden, CT 06514 / US
04 / BOYER, Stephen
233 Colony Street
Fairfield, CT 06430 / US
05 / WANG, Chunguang
27 Timberwood Trail
Hamden, CT 06514 / US
06 / PLUEMPE, Hans
Kirshbaumstrasse 9
D-42115 Wuppertal / DE
07 / FEURER, Achim
Erlbrunnenweg 5
69259 Wilhelmsfeld / DE
08 / BENNABI, Samir
Alsenstrabe 23 A
42103 Wuppertal / DE
 [2004/44]
Representative(s)Hirsch & Associés
154 Boulevard Haussmann
75008 Paris / FR
[N/P]
Former [2012/28]Hirsch & Associés
58, avenue Marceau
75008 Paris / FR
Former [2004/44]Cabinet Hirsch
58, avenue Marceau
75008 Paris / FR
Application number, filing date03705858.323.01.2003
[2004/44]
WO2003US01839
Priority number, dateUS20020349987P23.01.2002         Original published format: US 349987 P
[2004/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03062225
Date:31.07.2003
Language:EN
[2003/31]
Type: A1 Application with search report 
No.:EP1470121
Date:27.10.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 31.07.2003 takes the place of the publication of the European patent application.
[2004/44]
Type: B1 Patent specification 
No.:EP1470121
Date:11.07.2012
Language:EN
[2012/28]
Search report(s)International search report - published on:EP31.07.2003
ClassificationIPC:C07D401/12, C07D239/48, C07D413/12, C07D403/12, C07D413/14, C07D409/14, C07D471/04, A61K31/506
[2004/44]
CPC:
C07D239/48 (EP,US); A61K31/506 (EP,US); A61P11/06 (EP);
A61P15/00 (EP); A61P15/10 (EP); A61P19/10 (EP);
A61P25/00 (EP); A61P25/28 (EP); A61P27/06 (EP);
A61P35/00 (EP); A61P43/00 (EP); A61P7/02 (EP);
A61P9/10 (EP); A61P9/12 (EP); A61P9/14 (EP);
C07D401/12 (EP,US); C07D403/12 (EP,US); C07D409/14 (EP,US);
C07D413/12 (EP,US); C07D413/14 (EP,US); C07D471/04 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SI,   SK,   TR [2004/44]
TitleGerman:PYRIMIDIN-DERIVATE ALS RHO KINASE INHIBITOREN[2004/44]
English:PYRIMIDINE DERIVATIVES AS RHO-KINASE INHIBITORS[2004/44]
French:DERIVES PYRIMIDINE EN TANT QU'INHIBITEURS DE KINASE RHO[2004/44]
Entry into regional phase23.08.2004National basic fee paid 
23.08.2004Designation fee(s) paid 
23.08.2004Examination fee paid 
Examination procedure21.08.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
23.08.2004Examination requested  [2004/44]
01.09.2009Despatch of a communication from the examining division (Time limit: M06)
08.03.2010Reply to a communication from the examining division
20.02.2012Communication of intention to grant the patent
31.05.2012Fee for grant paid
31.05.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  01.09.2009
Opposition(s)12.04.2013No opposition filed within time limit [2013/25]
Fees paidRenewal fee
31.01.2005Renewal fee patent year 03
12.01.2006Renewal fee patent year 04
12.01.2007Renewal fee patent year 05
14.01.2008Renewal fee patent year 06
14.01.2009Renewal fee patent year 07
13.01.2010Renewal fee patent year 08
14.01.2011Renewal fee patent year 09
11.01.2012Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU23.01.2003
AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
TR11.07.2012
BG11.10.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
GB23.01.2013
IE23.01.2013
LU23.01.2013
CH31.01.2013
FR31.01.2013
LI31.01.2013
MC31.01.2013
[2015/34]
Former [2015/32]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
TR11.07.2012
BG11.10.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
GB23.01.2013
IE23.01.2013
CH31.01.2013
FR31.01.2013
LI31.01.2013
MC31.01.2013
Former [2014/07]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
BG11.10.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
GB23.01.2013
IE23.01.2013
CH31.01.2013
FR31.01.2013
LI31.01.2013
MC31.01.2013
Former [2013/51]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
BG11.10.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
GB23.01.2013
CH31.01.2013
FR31.01.2013
LI31.01.2013
MC31.01.2013
Former [2013/50]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
BG11.10.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
CH31.01.2013
FR31.01.2013
LI31.01.2013
MC31.01.2013
Former [2013/48]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
BG11.10.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
CH31.01.2013
LI31.01.2013
MC31.01.2013
Former [2013/37]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
BG11.10.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
MC31.01.2013
Former [2013/35]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
BG11.10.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
Former [2013/23]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
IT11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
SK11.07.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
Former [2013/22]AT11.07.2012
BE11.07.2012
CY11.07.2012
CZ11.07.2012
DK11.07.2012
EE11.07.2012
FI11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
GR12.10.2012
ES22.10.2012
PT12.11.2012
Former [2013/21]AT11.07.2012
BE11.07.2012
CY11.07.2012
DK11.07.2012
FI11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
GR12.10.2012
PT12.11.2012
Former [2013/15]AT11.07.2012
BE11.07.2012
CY11.07.2012
FI11.07.2012
NL11.07.2012
SE11.07.2012
SI11.07.2012
GR12.10.2012
PT12.11.2012
Former [2013/13]AT11.07.2012
BE11.07.2012
CY11.07.2012
FI11.07.2012
SE11.07.2012
SI11.07.2012
GR12.10.2012
PT12.11.2012
Former [2013/12]AT11.07.2012
BE11.07.2012
CY11.07.2012
FI11.07.2012
SE11.07.2012
SI11.07.2012
GR12.10.2012
Former [2013/11]AT11.07.2012
BE11.07.2012
CY11.07.2012
FI11.07.2012
SI11.07.2012
GR12.10.2012
Former [2013/10]AT11.07.2012
BE11.07.2012
CY11.07.2012
FI11.07.2012
Former [2013/09]AT11.07.2012
BE11.07.2012
FI11.07.2012
Former [2013/08]AT11.07.2012
BE11.07.2012
Former [2013/07]AT11.07.2012
Cited inInternational search[X]WO0153331  (ADHEREX TECHNOLOGIES INC [CA], et al) [X] 1 * figure 23E; example 425 *;
 WO02060392  [ ] (SYNAPTIC PHARMA CORP [US]);
 [A]WO9719065  (CELLTECH THERAPEUTICS LTD [GB], et al) [A] 1-15 * abstract * * claim - * * example - *;
 [A]WO0119802  (TANABE SEIYAKU CO [JP], et al) [A] 1-15 * abstract * * claim - * * example - *;
 [A]DE19851421  (BOEHRINGER INGELHEIM PHARMA [DE]) [A] 1-15 * abstract * * claim - * * example - *
 [PX]  - BLACKBURN, THOMAS P. ET AL, "Preparation of pyrimidine and indol-2-one derivatives as galanin GAL3 receptor antagonists for the treatment of depression and/or anxiety", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 137:154941, URL: STN, XP002239813 [PX] 1 * abstract *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.