blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP1576089

EP1576089 - EXPANSION OF RENEWABLE STEM CELL POPULATIONS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.02.2011
Database last updated on 22.05.2024
Most recent event   Tooltip04.10.2013Lapse of the patent in a contracting state
New state(s): HU		published on 06.11.2013  [2013/45]
Applicant(s)For all designated states
Gamida-Cell Ltd.
5 Nahum Hafzadi Street
Ofer Building
Givat Shaul
95 484 Jerusalem / IL
[N/P]
Former [2010/15]For all designated states
Gamida Cell Ltd.
5 Nahum Hafzadi Street, Ofer Building, Givat Shaul
95 484 Jerusalem / IL
Former [2005/38]For all designated states
Gamida Cell Ltd.
5 Nahum Hafzadi Street, Ofer Building, Givat Shaul
95 484 Jerusalem / IL
Inventor(s)01 / PELED, Tony
19 Bareket Street
90 805 Mevaseret Zion / IL
02 / TREVES, Avi
10 Carmel Street
90 805 Mevaseret Zion / IL
03 / ROSEN, Oren
14 Moshe Kol Street
93 715 Jerusalem / IL
 [2005/38]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2007/46]Vossius & Partner
Postfach 86 07 67
81634 München / DE
Former [2005/38]Becker Kurig Straus
Patentanwälte Bavariastrasse 7
80336 München / DE
Application number, filing date03706871.526.01.2003
[2005/38]
WO2003IL00064
Priority number, dateUS20020350360P24.01.2002         Original published format: US 350360 P
US20020376183P30.04.2002         Original published format: US 376183 P
US20020404137P19.08.2002         Original published format: US 404137 P
IL2002015290417.11.2002         Original published format: IL 15290402
[2005/38]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03062369
Date:31.07.2003
Language:EN
[2003/31]
Type: A2 Application without search report 
No.:EP1576089
Date:21.09.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 31.07.2003 takes the place of the publication of the European patent application.
[2005/38]
Type: B1 Patent specification 
No.:EP1576089
Date:14.04.2010
Language:EN
[2010/15]
Search report(s)International search report - published on:US30.03.2006
(Supplementary) European search report - dispatched on:EP15.01.2007
ClassificationIPC:C12N5/00
[2006/23]
CPC:
C12N5/0647 (EP,US); A01N1/0226 (EP,US); A61K35/28 (EP,US);
A61P43/00 (EP); C07C51/09 (EP,US); C12M23/14 (US);
C12N5/067 (EP,US); G01N33/5008 (EP,US); G01N33/5023 (EP,US);
G01N33/5041 (EP,US); G01N33/5073 (EP,US); G01N33/5094 (EP,US);
A61K2035/122 (EP,US); A61K2035/124 (EP,US); A61K2039/515 (EP,US);
C12N2500/20 (EP,US); C12N2500/38 (EP,US); C12N2501/125 (EP,US);
C12N2501/145 (EP,US); C12N2501/23 (EP,US); C12N2501/2303 (EP,US);
C12N2501/2306 (EP,US); C12N2501/26 (EP,US); C12N2501/385 (EP,US);
C12N2501/599 (EP,US); C12N2501/999 (EP,US); C12N2503/02 (EP,US);
C12N2510/00 (EP,US); G01N2333/70567 (EP,US) (-)
C-Set:
C07C51/09, C07C59/72 (EP,US)
Former IPC [2005/38]C12N1/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SI,   SK,   TR [2005/38]
TitleGerman:EXPANSION ERNEUERBARER STAMMZELLPOPULATIONEN[2005/38]
English:EXPANSION OF RENEWABLE STEM CELL POPULATIONS[2005/38]
French:DEVELOPPEMENT DE POPULATIONS DE CELLULES SOUCHES RENOUVELABLES[2005/38]
Entry into regional phase28.07.2004National basic fee paid 
28.07.2004Search fee paid 
28.07.2004Designation fee(s) paid 
28.07.2004Examination fee paid 
Examination procedure20.08.2003Request for preliminary examination filed
International Preliminary Examining Authority: US
28.07.2004Amendment by applicant (claims and/or description)
28.07.2004Examination requested  [2005/38]
13.04.2007Despatch of a communication from the examining division (Time limit: M06)
23.10.2007Reply to a communication from the examining division
24.01.2008Despatch of a communication from the examining division (Time limit: M04)
28.05.2008Reply to a communication from the examining division
25.02.2009Despatch of a communication from the examining division (Time limit: M04)
07.07.2009Reply to a communication from the examining division
15.10.2009Communication of intention to grant the patent
25.02.2010Fee for grant paid
25.02.2010Fee for publishing/printing paid
Divisional application(s)EP10003540.1  / EP2206773
EP10010858.8  / EP2305794
Opposition(s)17.01.2011No opposition filed within time limit [2011/12]
Fees paidRenewal fee
12.01.2005Renewal fee patent year 03
12.01.2006Renewal fee patent year 04
25.01.2007Renewal fee patent year 05
30.01.2008Renewal fee patent year 06
29.01.2009Renewal fee patent year 07
26.01.2010Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT14.04.2010
CZ14.04.2010
DK14.04.2010
EE14.04.2010
FI14.04.2010
HU14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
SK14.04.2010
TR14.04.2010
CY21.04.2010
BG14.07.2010
GR15.07.2010
PT16.08.2010
[2013/45]
Former [2013/44]AT14.04.2010
CZ14.04.2010
DK14.04.2010
EE14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
SK14.04.2010
TR14.04.2010
CY21.04.2010
BG14.07.2010
GR15.07.2010
PT16.08.2010
Former [2013/42]AT14.04.2010
CZ14.04.2010
DK14.04.2010
EE14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
SK14.04.2010
CY21.04.2010
BG14.07.2010
GR15.07.2010
PT16.08.2010
Former [2011/10]AT14.04.2010
CZ14.04.2010
DK14.04.2010
EE14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
SK14.04.2010
CY21.04.2010
GR15.07.2010
PT16.08.2010
Former [2011/08]AT14.04.2010
DK14.04.2010
EE14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
CY21.04.2010
GR15.07.2010
PT16.08.2010
Former [2011/07]AT14.04.2010
DK14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
CY21.04.2010
GR15.07.2010
Former [2011/03]AT14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
CY21.04.2010
GR15.07.2010
Former [2011/01]AT14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
GR15.07.2010
Former [2010/52]AT14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
SI14.04.2010
Former [2010/50]AT14.04.2010
FI14.04.2010
NL14.04.2010
SE14.04.2010
Former [2010/49]AT14.04.2010
NL14.04.2010
SE14.04.2010
Former [2010/45]NL14.04.2010
Documents cited:Search[PX]  - FIBACH E ET AL, "RETINOIC ACID ANTAGONIST INHIBITS CD38 ANTIGEN EXPRESSION ON HUMAN HEMATOPOIETIC CELLS", BLOOD, W.B.SAUNDERS COMPANY, ORLANDO, FL, US, (20021116), vol. 100, no. 11, ISSN 0006-4971, page 172A,644, XP009058480 [PX] 1-46 * the whole document *
 [A]  - RAMSFJELL VESLEMOY ET AL, "Distinct requirements for optimal growth and in vitro expansion of human CD34+CD38- bone marrow long-term culture-initiating cells (LTC-IC), extended LTC-IC, and murine in vivo long-term reconstituting stem cells", BLOOD, W.B.SAUNDERS COMPANY, ORLANDO, FL, US, (19991215), vol. 94, no. 12, ISSN 0006-4971, pages 4093 - 4102, XP002255402 [A] 1-46 * the whole document *
 [A]  - EMERSON S G, "EX VIVO EXPANSION OF HEMATOPOIETIC PRECURSORS, PROGENITORS, AND STEM CELLS: THE NEXT GENERATION OF CELLULAR THERAPEUTICS", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, (19960415), vol. 87, no. 8, ISSN 0006-4971, pages 3082 - 3088, XP002909281 [A] 1-46 * the whole document *
 [A]  - SILVENOINEN OLLI ET AL, "CD38 signal transduction in human B cell precursors. Rapid induction of tyrosine phosphorylation, activation of syk tyrosine kinase, and phosphorylation of phospholipase C-gamma and phosphatidylinositol 3-kinase", JOURNAL OF IMMUNOLOGY, (1996), vol. 156, no. 1, ISSN 0022-1767, pages 100 - 107, XP002411264 [A] 1-46 * the whole document *
 [A]  - TODISCO ELISABETTA ET AL, "CD38 ligation inhibits normal and leukemic myelopoiesis", BLOOD, (20000115), vol. 95, no. 2, ISSN 0006-4971, pages 535 - 542, XP002411265 [A] 1-46 * the whole document *
 [A]  - KUMAGAI MASA-AKI ET AL, "Ligation of CD38 Suppresses Human B Lymphopoiesis", JOURNAL OF EXPERIMENTAL MEDICINE, (1995), vol. 181, no. 3, ISSN 0022-1007, pages 1101 - 1110, XP002411266 [A] 1-46 * the whole document *

DOI:   http://dx.doi.org/10.1084/jem.181.3.1101
International search[X]  - JOHNSON A.T. ET AL, "Synthesis and biological activity of high-affinity retinoic acid receptor antagonists", BIOORG & MED. CHEM., (199907), vol. 7, no. 7, pages 1321 - 1338, XP000901411

DOI:   http://dx.doi.org/10.1016/S0968-0896(99)00055-3
Examination   - BHATIA ET AL, "Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice.", PNAS, (1997), vol. 94, pages 5320 - 5325
    - FERGUSON ET AL, "The effects of different culture media, glucose, pyridine nucleotides and adenosine on the activity of 11beta-hydroxysteroid dehydrogenase in rat Leydig cells.", MOLECULAR AND CELLULAR ENDOCRINOLOGY, (1999), vol. 158, pages 37 - 44
by applicantUS3687808
 US5545807
 US5545806
 US5569825
 WO9712853
 US5625126
 US5633425
 US5661016
 US6303374
    - LEE ET AL., BIOL. CHEM., (1999), vol. 380, pages 785 - 793
    - MUNSHI CB; GRAEFF R; LEE HC, J BIOL CHEM, (20021220), vol. 277, no. 51, pages 49453 - 8
    - PODESTA, FASEB J., (2000), vol. 14, pages 680 - 690
    - HOOGENBOOM; WINTER, J. MOL. BIOL., (1991), vol. 227, page 381
    - MARKS ET AL., J. MOL. BIOL., (1991), vol. 222, page 581
    - COLE ET AL., Monoclonal Antibodies and Cancer Therapy, ALAN R. LISS, (1985), page 77
    - BOERNER ET AL., J. IMMUNOL., (1991), vol. 147, no. 1, pages 86 - 95
    - MARKS ET AL., BIO/TECHNOLOGY, (1992), vol. 10, pages 779 - 783
    - LONBERG ET AL., NATURE, (1994), vol. 368, pages 856 - 859
    - MORRISON, NATURE, (1994), vol. 368, pages 812 - 13
    - FISHWILD ET AL., NATURE BIOTECHNOLOGY, (1996), vol. 14, pages 845 - 51
    - NEUBERGER, NATURE BIOTECHNOLOGY, (1996), vol. 14, page 826
    - LONBERG; HUSZAR, INTERN. REV. IMMUNOL., (1995), vol. 13, pages 65 - 93
    - KROSCHWITZ, J. I.,, The Concise Encyclopedia Of Polymer Science And Engineering, JOHN WILEY & SONS, (1990), pages 858 - 859
    - ENGLISCH ET AL., ANGEWANDTE CHEMIE, (1991), vol. 30, page 613
    - "Chapter 15,", SANGHVI, Y. S., Antisense Research and Applications, CRC PRESS, (1993), pages 289 - 302
    - SANGHVI YS ET AL., Antisense Research and Applications, CRC PRESS, (1993), pages 276 - 278
    - "Gene Therapy", Advanced in Pharmacology, ACADEMIC PRESS, (1997), vol. 40
    - TROUNSON AO, REPROD FERTIL DEV, (2001), vol. 13, page 523
    - ROACH ML, METHODS MOL BIOL, (2002), vol. 185, page 1
    - SMITH AG, ANNU REV CELL DEV BIOL, (2001), vol. 17, page 435
    - MIRAGLIA, S. ET AL., BLOOD, (1997), vol. 90, page 5013
    - UCHIDA, N. ET AL., PROC. NATL. ACAD. SCI. USA, (2000), vol. 97, page 14720
    - SIMMONS, P.J. ET AL., BLOOD, (1991), vol. 78, page 55
    - PROCKOP DJ, CYTOTHERAPY, (2001), vol. 3, page 393
    - BOHMER RM, FETAL DIAGN THER, (2002), vol. 17, page 83
    - ROWLEY SD ET AL., BONE MARROW TRANSPLANT, (1998), vol. 21, page 1253
    - "This embodiment of the present invention is of particular", STEM CELLS, (2000), vol. 18, page 295
    - CANAN-KOCH ET AL., J. MED. CHEM., vol. 39, no. 17, pages 3229 - 3234
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.