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Extract from the Register of European Patents

EP About this file: EP1495020

EP1495020 - N-(MORPHOLIN-2YL) METHYL ACETAMIDE DERIVATIVES AS CCR-3 ANTAGONISTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  11.11.2005
Database last updated on 16.09.2024
Most recent event   Tooltip11.11.2005Application deemed to be withdrawnpublished on 28.12.2005  [2005/52]
Applicant(s)For all designated states
GLAXO GROUP LIMITED
Glaxo Wellcome House, Berkeley Avenue
Greenford, Middlesex UB6 0NN / GB
[N/P]
Former [2005/02]For all designated states
GLAXO GROUP LIMITED
Glaxo Wellcome House Berkeley Avenue
Greenford, Middlesex UB6 ONN / GB
Inventor(s)01 / ANCLIFF, Rachael Ann
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
02 / COOK, Caroline Mary
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
03 / ELDRED, Colin David
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
04 / GORE, Paul Martin
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
05 / HARRISON, Lee Andrew
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
06 / HAYES, Martin Alistair
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
07 / HODGSON, Simon Teanby
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
08 / JUDD, Duncan Bruce
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
09 / KEELING, Suzanne Elaine
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
10 / LEWELL, Xiao Qing
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
11 / MILLS, Gail
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
12 / ROBERTSON, Graeme Michael
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
13 / SWANSON, Stephen
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
14 / WALKER, Andrew John
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
15 / WILKINSON, Mark
GlaxoSmithKline, Gunnels Wood Road
Stevenage, Hertfordshire SG1 2NY / GB
 [2005/02]
Representative(s)Povey, Alexander W.G.
GlaxoSmithKline
Global Patents (CN925.1)
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[N/P]
Former [2005/02]Povey, Alexander W.G.
GlaxoSmithKline Corporate Intellectual Property (CN925.1) 980 Great West Road
Brentford, Middlesex TW8 9GS / GB
Application number, filing date03745300.827.03.2003
[2005/02]
WO2003EP03350
Priority number, dateGB2002000744528.03.2002         Original published format: GB 0207445
[2005/02]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03082863
Date:09.10.2003
Language:EN
[2003/41]
Type: A1 Application with search report 
No.:EP1495020
Date:12.01.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 09.10.2003 takes the place of the publication of the European patent application.
[2005/02]
Search report(s)International search report - published on:EP09.10.2003
ClassificationIPC:C07D413/12, C07D241/08, C07D309/38, A61K31/5377, A61P11/06, A61P17/06, A61P17/04, A61P25/28, A61P37/06, A61P37/08, A61P9/10, A61P1/06, A61P27/14
[2005/02]
CPC:
C07D413/12 (EP); A61P1/06 (EP); A61P11/06 (EP);
A61P17/04 (EP); A61P17/06 (EP); A61P25/28 (EP);
A61P27/14 (EP); A61P27/16 (EP); A61P29/00 (EP);
A61P37/06 (EP); A61P37/08 (EP); A61P9/10 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/02]
Extension statesALNot yet paid
LT12.10.2004
LV12.10.2004
MKNot yet paid
TitleGerman:N-(MORPHOLIN-2-YL)METHYLACETAMID DERIVATE ALS FÜR DIE BEHANDLUNG VON ENTZÜNDLICHEN ERKRANKUNGEN GEEIGNETE CCR-3-ANTAGONISTEN[2005/02]
English:N-(MORPHOLIN-2YL) METHYL ACETAMIDE DERIVATIVES AS CCR-3 ANTAGONISTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES[2005/02]
French:DERIVES DE N-(MORPHOLIN-2YL) METHYLE ACETAMIDE SERVANT D'ANTAGONISTES DE CCR-3 ET UTILISES DANS LE TRAITEMENT DE MALADIES INFLAMMATOIRES[2005/02]
Entry into regional phase12.10.2004National basic fee paid 
12.10.2004Designation fee(s) paid 
12.10.2004Examination fee paid 
Examination procedure30.09.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
12.10.2004Examination requested  [2005/02]
15.02.2005Despatch of a communication from the examining division (Time limit: M04)
25.06.2005Application deemed to be withdrawn, date of legal effect  [2005/52]
29.07.2005Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2005/52]
Fees paidRenewal fee
04.03.2005Renewal fee patent year 03
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Cited inInternational search[X]DE19624668  (KLINGE CO CHEM PHARM FAB [DE]) [X] 1-23 * example 374; claim 1 *;
 [A]EP0903349  (HOFFMANN LA ROCHE [CH]) [A] 1-23 * page 45, line 42 - line 47; claims 1,72 *;
 [PX]WO0226722  (GLAXO GROUP LTD [GB], et al) [PX] 1-23 * intermediates (V), p.17, intermediates (IV), p.15; page 24, line 24 - line 28; claim 1 *
 [X]  - KATO S ET AL, "NOVEL BENZAMIDES AS SELECTIVE AND POTENT GASTRIC PROKINETIC AGENTS 1. SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS OF N-(2-MORPHOLINYL)ALKYLBENZAMIDES", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (199005), vol. 33, no. 5, ISSN 0022-2623, pages 1406 - 1413, XP001037844 [X] 16,17 * scheme II, compound 9; Scheme IV, compound 15c; Table I; Table II, compound 48. *

DOI:   http://dx.doi.org/10.1021/jm00167a020
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.