blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP1546373

EP1546373 - METHODS FOR MEASURING RATES OF REVERSE CHOLESTEROL TRANSPORT IN VIVO, AS AN INDEX OF ANTI-ATHEROGENESIS [Right-click to bookmark this link]
Former [2005/26]METHODS FOR MEASURING RATES OF RESERVE CHOLESTEROL TRANSPORT IN VIVO, AS AN INDEX OF ANTI-ATHEROGENESIS
[2008/14]
StatusNo opposition filed within time limit
Status updated on  02.10.2009
Database last updated on 24.04.2024
Most recent event   Tooltip30.09.2011Lapse of the patent in a contracting state
New state(s): CY, TR		published on 02.11.2011  [2011/44]
Applicant(s)For all designated states
The Regents of the University of California
1111 Franklin Street, 12th Floor
Oakland, CA 94607 / US
[N/P]
Former [2008/48]For all designated states
The Regents of the University of California
1111 Franklin Street, 12th Floor
Oakland, CA 94607-5200 / US
Former [2005/26]For all designated states
The Regents of the University of California
1111 Franklin Street, 12th Floor
Oakland, CA 94607-5200 / US
Inventor(s)01 / HELLERSTEIN, Marc, K.
4 Anson Way
Kensington, CA 94708 / US
 [2005/26]
Representative(s)Holmberg-Schwindt, Tor Martin, et al
Bergenstrahle & Lindvall AB
P.O. Box 17704
118 93 Stockholm / SE
[N/P]
Former [2005/26]Holmberg, Martin, et al
Bergenstrahle & Lindvall AB P.O. Box 17704
118 93 Stockholm / SE
Application number, filing date03749756.715.09.2003
[2005/26]
WO2003US29361
Priority number, dateUS20020410352P13.09.2002         Original published format: US 410352 P
[2005/26]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004025270
Date:25.03.2004
Language:EN
[2004/13]
Type: A2 Application without search report 
No.:EP1546373
Date:29.06.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 25.03.2004 takes the place of the publication of the European patent application.
[2005/26]
Type: B1 Patent specification 
No.:EP1546373
Date:26.11.2008
Language:EN
[2008/48]
Search report(s)International search report - published on:US24.03.2005
(Supplementary) European search report - dispatched on:EP17.08.2005
ClassificationIPC:C12Q1/60, C12Q1/00, G01N31/00, G01N33/92, A61K51/00, A61M36/14, A61K49/00, A61K51/04, A61K51/12, G01N33/60
[2005/39]
CPC:
A61K49/0004 (EP,US); A61K51/04 (EP,US); A61K51/0493 (EP,US);
A61K51/1224 (EP,US); A61P9/00 (EP); A61P9/10 (EP)
Former IPC [2005/26]C12Q1/60, C12Q1/00, G01N31/00, G01N33/92, A61K51/00, A61M36/14
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/26]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:VERFAHREN ZUR MESSUNG DER GESCHWINDIGKEITEN DES CHOLESTERINRÜCKWÄRTSTRANSPORTS IN VIVO ALS INDEX FÜR ANTI-ARTHEROGENESE[2008/14]
English:METHODS FOR MEASURING RATES OF REVERSE CHOLESTEROL TRANSPORT IN VIVO, AS AN INDEX OF ANTI-ATHEROGENESIS[2008/14]
French:METHODES PERMETTANT DE MESURER LES TAUX DE TRANSPORT INVERSE DU CHOLESTEROL IN VIVO UTILISES COMME INDICE D'ANTI-ATHEROGENICITE[2005/26]
Former [2005/26]VERFAHREN ZUR MESSUNG DER GESCHWINDIGKEITEN DES RESERVE-CHOLESTERIN-TRANSPORTS IN VIVO ALS INDEX FÜR ANTI-ARTHEROGENESE
Former [2005/26]METHODS FOR MEASURING RATES OF RESERVE CHOLESTEROL TRANSPORT IN VIVO, AS AN INDEX OF ANTI-ATHEROGENESIS
Entry into regional phase11.04.2005National basic fee paid 
11.04.2005Search fee paid 
11.04.2005Designation fee(s) paid 
11.04.2005Examination fee paid 
Examination procedure11.04.2005Examination requested  [2005/26]
06.12.2005Despatch of a communication from the examining division (Time limit: M06)
01.06.2006Reply to a communication from the examining division
04.10.2006Despatch of a communication from the examining division (Time limit: M04)
14.02.2007Reply to a communication from the examining division
21.04.2008Communication of intention to grant the patent
19.08.2008Fee for grant paid
19.08.2008Fee for publishing/printing paid
Opposition(s)27.08.2009No opposition filed within time limit [2009/45]
Fees paidRenewal fee
11.04.2005Renewal fee patent year 03
27.09.2006Renewal fee patent year 04
26.09.2007Renewal fee patent year 05
25.09.2008Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY26.11.2008
CZ26.11.2008
EE26.11.2008
FI26.11.2008
IT26.11.2008
RO26.11.2008
SI26.11.2008
SK26.11.2008
TR26.11.2008
BG26.02.2009
GR27.02.2009
ES08.03.2009
PT27.04.2009
HU27.05.2009
[2011/43]
Former [2011/31]CZ26.11.2008
EE26.11.2008
FI26.11.2008
IT26.11.2008
RO26.11.2008
SI26.11.2008
SK26.11.2008
BG26.02.2009
GR27.02.2009
ES08.03.2009
PT27.04.2009
HU27.05.2009
Former [2011/14]CZ26.11.2008
EE26.11.2008
FI26.11.2008
IT26.11.2008
RO26.11.2008
SI26.11.2008
SK26.11.2008
BG26.02.2009
GR27.02.2009
ES08.03.2009
PT27.04.2009
Former [2010/48]CZ26.11.2008
EE26.11.2008
FI26.11.2008
RO26.11.2008
SI26.11.2008
SK26.11.2008
BG26.02.2009
GR27.02.2009
ES08.03.2009
PT27.04.2009
Former [2009/43]CZ26.11.2008
EE26.11.2008
FI26.11.2008
RO26.11.2008
SI26.11.2008
SK26.11.2008
BG26.02.2009
ES08.03.2009
PT27.04.2009
Former [2009/39]CZ26.11.2008
EE26.11.2008
FI26.11.2008
RO26.11.2008
SI26.11.2008
BG26.02.2009
ES08.03.2009
PT27.04.2009
Former [2009/36]EE26.11.2008
FI26.11.2008
RO26.11.2008
SI26.11.2008
BG26.02.2009
ES08.03.2009
Former [2009/35]FI26.11.2008
SI26.11.2008
BG26.02.2009
ES08.03.2009
Former [2009/26]FI26.11.2008
SI26.11.2008
ES08.03.2009
Former [2009/20]ES08.03.2009
Documents cited:Search[X]WO9320800  (KINNUNEN PAAVO KAI JOHANNES [FI]) [X] 1 * page 8; example -; claim - *;
 [X]US5338686  (HELLERSTEIN MARC K [US]) [X] 1-26 * example 6; table 5B *;
 [X]WO9513096  (PEPTIDE DELIVERY SYSTEMS PTY L [AU], et al) [X] 1-26 * page 6, line 4 - line 11 *;
 [PX]WO03068919  (UNIV CALIFORNIA [US]) [PX] 1-26* page 24 - page 25; example 7; claims 1,59 *;
 [X]  - OUGUERRAM K ET AL, "A new labeling approach using stable isotopes to study in vivo plasma cholesterol metabolism in humans", METABOLISM: CLINICAL AND EXPERIMENTAL 2002 UNITED STATES, (2002), vol. 51, no. 1, ISSN 0026-0495, pages 5 - 11, XP002339483 [X] 1-26 * abstract *

DOI:   http://dx.doi.org/10.1053/meta.2002.29006
 [X]  - LUTTON C ET AL, "Critical analysis of the use of 14C-acetate for measuring in vivo rat cholesterol synthesis.", REPRODUCTION, NUTRITION, DEVELOPMENT. 1990, (1990), vol. 30, no. 1, ISSN 0926-5287, pages 71 - 84, XP008050735 [X] 26 * abstract *
 [X]  - BANDSMA R H J ET AL, "The contribution of newly synthesized cholesterol to bile salt synthesis in rats quantified by mass isotopomer distribution analysis", BIOCHIMICA AND BIOPHYSICA ACTA. MOLECULAR AND CELL BIOLOGY OF LIPIDS, ELSEVIER, AMSTERDAM, NL, (20000131), vol. 1483, no. 3, ISSN 1388-1981, pages 343 - 351, XP004277311 [X] 1 * abstract *

DOI:   http://dx.doi.org/10.1016/S1388-1981(99)00192-4
 [X]  - SCHEIBNER J ET AL, "Bile acid synthesis from newly synthesized vs. preformed cholesterol precursor pools in the rat.", HEPATOLOGY (BALTIMORE, MD.) JUN 1993, (199306), vol. 17, no. 6, ISSN 0270-9139, pages 1095 - 1102, XP008050733 [X] 1-26 * abstract *

DOI:   http://dx.doi.org/10.1016/0270-9139(93)90128-A
International search[A]  - BRAVO, E. ET AL., "Decreased Hepatic Uptake and Processing of High Density Lipoprotein Unesterfied Cholesterol and Cholesteryl Ester with Age in the Rat", J. BIOCHEM, (1994), vol. 116, pages 1088 - 1095, XP008042386
 [A]  - MAENTAUSTA, O. ET AL., "Radioimmunoassay of Conjugated Cholic Acid, Chenodeoxycholic Acid, and Deoxycholic Acid from Human Serum, with Use of 125I-labeled Ligands", CLINICAL CHEMISTRY, (1979), vol. 25, no. 2, pages 264 - 268, XP002983357
 [X]  - BROWN, A.S. ET AL., "Treating Patients With Documented Atherosclerosis to National Cholesterol Education Program-Recommended Low-Density-Lipoprotein Cholesterol Goals With Atorvastatin, Fluvastatin, Lovastatin and Simvastatin", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, (199809), vol. 32, no. 3, pages 665 - 672, XP002983358

DOI:   http://dx.doi.org/10.1016/S0735-1097(98)00300-3
 [X]  - RODA, A. ET AL., "Results with Six "Kit" Radioimmunoassays for Primary Bile Acids in Human Serum Intercompared", CLINICAL CHEMISTRY, (1980), vol. 26, no. 12, pages 1677 - 1682, XP002983359
 [X]  - TINT, G.S. ET AL., "Transformation of 5 alpha-cholest-7en-3 beta-ol to cholesterol and cholestanol in cerebrotendinous xanthomatosis", JOURNAL OF LIPID RESEARCH, (1974), vol. 15, pages 256 - 261, XP002983360
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.