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Extract from the Register of European Patents

EP About this file: EP1542700

EP1542700 - ZOLEDRONIC ACID FOR PREVENTING OR REDUCING SECONDARY FRACTURES AFTER HIP FRACTURE [Right-click to bookmark this link]
Former [2005/25]METHOD FOR PREVENTING OR REDUCING SECONDARY FRACTURES AFTER HIP FRACTURE
[2011/18]
StatusPatent revoked
Status updated on  24.01.2014
Database last updated on 11.09.2024
Most recent event   Tooltip24.06.2022Lapse of the patent in a contracting state
New state(s): HU		published on 27.07.2022  [2022/30]
Applicant(s)For:BE  BG  CH  CY  CZ  DE  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT  RO  SE  SI  SK  TR 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1230 Wien / AT
For all designated states
Lyles, Kenneth W.
1020 Monmouth Avenue
Durham, NC 27701 / US
[N/P]
Former [2011/45]For:BE  BG  CH  CY  CZ  DE  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT  RO  SE  SI  SK  TR 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1230 Wien / AT
For all designated states
Lyles, Kenneth W.
3515 Cottonwood Drive
Durham, NC 27707 / US
Former [2011/21]For:BE  BG  CH  CY  CZ  DE  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT  RO  SE  SI  SK  TR 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1230 Wien / AT
For all designated states
Lyles, Kenneth W.
3515 Cottonwood Drive
Durham, NC 27707 / US
Former [2006/29]For:BE  BG  CH  CY  CZ  DE  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1230 Wien / AT
For all designated states
Lyles, Kenneth W.
3515 Cottonwood Drive
Durham, NC 27707 / US
Former [2005/25]For:BE  BG  CH  CY  CZ  DE  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LU  MC  NL  PT 
Novartis AG
Lichtstrasse 35
4056 Basel / CH
For:AT 
Novartis Pharma GmbH
Brunner Strasse 59
1230 Wien / AT
For all designated states
Lyles, Kenneth W.
3515 Cottonwood Drive
Durham, NC 27707 / US
Inventor(s)01 / LYLES, Kenneth, W.
1020 Monmouth Avenue
Durham, NC 27707 / US
02 / HOROWITZ, Zebulun, David
83 Blackburn Road
Basking Ridge, NJ 07920 / US
 [2012/16]
Former [2005/25]01 / LYLES, Kenneth, W.
3515 Cottonwood Drive
Durham, NC 27707 / US
02 / HOROWITZ, Zebulun, David
83 Blackburn Road
Basking Ridge, NJ 07920 / US
Representative(s)Leon, Susanna Iris
Novartis AG
Corporate Intellectual Property
P.O. Box
4002 Basel / CH
[N/P]
Former [2011/45]Leon, Susanna Iris
Novartis AG Corporate Intellectual Property P.O. Box
4002 Basel / CH
Former [2005/25]Leon, Susanna Iris
Novartis AG Corporate Intellectual Property P.O. Box
4002 Basel / CH
Application number, filing date03750546.815.09.2003
[2005/25]
WO2003EP10239
Priority number, dateUS20020411067P16.09.2002         Original published format: US 411067 P
[2005/25]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004024166
Date:25.03.2004
Language:EN
[2004/13]
Type: A1 Application with search report 
No.:EP1542700
Date:22.06.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 25.03.2004 takes the place of the publication of the European patent application.
[2005/25]
Type: B1 Patent specification 
No.:EP1542700
Date:09.11.2011
Language:EN
[2011/45]
Search report(s)International search report - published on:EP25.03.2004
ClassificationIPC:A61K31/675, A61P19/00, A61P19/10
[2005/25]
CPC:
A61K31/592 (EP,US); A61K31/59 (EP,US); A61K31/663 (EP,US);
A61K31/675 (EP,US); A61K33/06 (EP,US); A61P19/00 (EP);
A61P19/08 (EP); A61P19/10 (EP) (-)
C-Set:
A61K31/592, A61K2300/00 (EP,US);
A61K31/663, A61K2300/00 (US,EP);
A61K31/675, A61K2300/00 (US,EP);
A61K33/06, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/25]
TitleGerman:ZOLEDRONSÄURE ZUR PRÄVENTION ODER VERMINDERUNG VON SEKUNDÄRFRAKTUREN NACH HÜFTFRAKTUR[2011/18]
English:ZOLEDRONIC ACID FOR PREVENTING OR REDUCING SECONDARY FRACTURES AFTER HIP FRACTURE[2011/18]
French:L'ACIDE ZOLEDRONIQUE POUR LA PREVENTION OU LA REDUCTION DE FRACTURES SECONDAIRES CONSECUTIVES A UNE FRACTURE DE LA HANCHE[2011/18]
Former [2005/25]VERWENDUNG VON BIPHOSPHONATEN ZUR PRÄVENTION ODER VERMINDERUNG VON SEKUNDÄRFRAKTUREN NACH HÜFTFRAKTUR
Former [2005/25]METHOD FOR PREVENTING OR REDUCING SECONDARY FRACTURES AFTER HIP FRACTURE
Former [2005/25]METHODE DE PREVENTION OU DE REDUCTION DE FRACTURES SECONDAIRES CONSECUTIVES A UNE FRACTURE DE LA HANCHE
Entry into regional phase18.04.2005National basic fee paid 
18.04.2005Designation fee(s) paid 
18.04.2005Examination fee paid 
Examination procedure17.03.2004Request for preliminary examination filed
International Preliminary Examining Authority: EP
18.04.2005Examination requested  [2005/25]
08.08.2005Despatch of a communication from the examining division (Time limit: M06)
22.05.2006Reply to a communication from the examining division
01.08.2007Despatch of a communication from the examining division (Time limit: M06)
19.03.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
20.05.2008Reply to a communication from the examining division
04.05.2011Communication of intention to grant the patent
05.08.2011Fee for grant paid
05.08.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  08.08.2005
Opposition(s)Opponent(s)01  31.07.2012  06.08.2012  ADMISSIBLE
Actavis Group PTC EHF
Reykjavikurvegi 76-78
220 Hafnarfjordur / IS
Opponent's representative
Vossius & Partner Patentanwälte Rechtsanwälte mbB, et al, et al
Siebertstrasse 3
81675 München / DE
 02  07.08.2012  06.12.2012  WITHDRAWN
Generics [UK] Limited
Albany Gate Darkes Lane Potters Bar
Hertfordshire EN6 1AG / GB
Opponent's representative
Gillard, Richard Edward, et al, et al
Elkington and Fife LLP
Thavies Inn House
3-4 Holborn Circus
London EC1N 2HA / GB
 03  09.08.2012  16.04.2013  WITHDRAWN
Taylor Wessing LLP
5 New Street Square
London EC4A 3TW / GB
Opponent's representative
Sant, David Paul
Taylor Wessing LLP
5 New Street Square
London EC4A 3TW / GB
 [N/P]
Former [2013/21]
Opponent(s)01  31.07.2012  06.08.2012  ADMISSIBLE
Actavis Group PTC EHF
Reykjavikurvegi 76-78
220 Hafnarfjordur / IS
Opponent's representative
Vossius & Partner, et al, et al
Siebertstrasse 4
81675 München / DE
 02  07.08.2012  06.12.2012  WITHDRAWN
Generics [UK] Limited
Albany Gate Darkes Lane Potters Bar
Hertfordshire EN6 1AG / GB
Opponent's representative
Gillard, Richard Edward, et al, et al
Elkington and Fife LLP Thavies Inn House 3-4 Holborn Circus
London EC1N 2HA / GB
 03  09.08.2012  16.04.2013  WITHDRAWN
Taylor Wessing LLP
5 New Street Square
London EC4A 3TW / GB
Opponent's representative
Sant, David Paul
Taylor Wessing LLP
5 New Street Square
London EC4A 3TW / GB
Former [2013/03]
Opponent(s)01  31.07.2012  06.08.2012  ADMISSIBLE
Actavis Group PTC EHF
Reykjavikurvegi 76-78
220 Hafnarfjordur / IS
Opponent's representative
Vossius & Partner, et al, et al
Siebertstrasse 4
81675 München / DE
 02  07.08.2012  06.12.2012  WITHDRAWN
Generics [UK] Limited
Albany Gate Darkes Lane Potters Bar
Hertfordshire EN6 1AG / GB
Opponent's representative
Gillard, Richard Edward, et al, et al
Elkington and Fife LLP Thavies Inn House 3-4 Holborn Circus
London EC1N 2HA / GB
 03  09.08.2012  17.08.2012  ADMISSIBLE
Taylor Wessing LLP
5 New Street Square
London EC4A 3TW / GB
Opponent's representative
Sant, David Paul
Taylor Wessing LLP
5 New Street Square
London EC4A 3TW / GB
Former [2012/38]
Opponent(s)01  31.07.2012  06.08.2012  ADMISSIBLE
Actavis Group PTC EHF
Reykjavikurvegi 76-78
220 Hafnarfjordur / IS
Opponent's representative
Vossius & Partner, et al, et al
Siebertstrasse 4
81675 München / DE
 02  07.08.2012  10.08.2012  ADMISSIBLE
Generics [UK] Limited
Albany Gate Darkes Lane Potters Bar
Hertfordshire EN6 1AG / GB
Opponent's representative
Gillard, Richard Edward, et al, et al
Elkington and Fife LLP Thavies Inn House 3-4 Holborn Circus
London EC1N 2HA / GB
 03  09.08.2012  17.08.2012  ADMISSIBLE
Taylor Wessing LLP
5 New Street Square
London EC4A 3TW / GB
Opponent's representative
Sant, David Paul
Taylor Wessing LLP
5 New Street Square
London EC4A 3TW / GB
Former [2012/37]
Opponent(s)01  31.07.2012  06.08.2012  ADMISSIBLE
Actavis Group PTC EHF
Reykjavikurvegi 76-78
220 Hafnarfjordur / IS
Opponent's representative
Vossius & Partner, et al, et al
Siebertstrasse 4
81675 München / DE
 02  07.08.2012    WITHDRAWN
Generics [UK] Limited
Albany Gate Darkes Lane Potters Bar
Hertfordshire EN6 1AG / GB
Opponent's representative
Gillard, Richard Edward, et al, et al
Elkington and Fife LLP Thavies Inn House 3-4 Holborn Circus
London EC1N 2HA / GB
Former [2012/36]
Opponent(s)01  31.07.2012   
Actavis Group PTC EHF
Reykjavikurvegi 76-78
220 Hafnarfjordur / IS
Opponent's representative
Vossius & Partner, et al, et al
Siebertstrasse 4
81675 München / DE
13.09.2012Invitation to proprietor to file observations on the notice of opposition
26.09.2013Despatch of communication that the patent will be revoked
06.10.2013Legal effect of revocation of patent [2014/09]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
20.05.2008Request for further processing filed
20.05.2008Full payment received (date of receipt of payment)
18.05.2006Request for further processing filed
18.05.2006Full payment received (date of receipt of payment)
Request granted
02.06.2006Decision despatched
Fees paidRenewal fee
30.09.2005Renewal fee patent year 03
02.10.2006Renewal fee patent year 04
28.09.2007Renewal fee patent year 05
31.03.2008Renewal fee patent year 06
11.09.2009Renewal fee patent year 07
14.09.2010Renewal fee patent year 08
30.09.2011Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.09.2003
CH09.11.2011
CY09.11.2011
CZ09.11.2011
DK09.11.2011
EE09.11.2011
FI09.11.2011
LI09.11.2011
RO09.11.2011
SE09.11.2011
SI09.11.2011
SK09.11.2011
BG09.02.2012
IE15.09.2012
MC30.09.2012
[2022/30]
Former [2014/20]CH09.11.2011
CY09.11.2011
CZ09.11.2011
DK09.11.2011
EE09.11.2011
FI09.11.2011
LI09.11.2011
RO09.11.2011
SE09.11.2011
SI09.11.2011
SK09.11.2011
BG09.02.2012
IE15.09.2012
MC30.09.2012
Former [2013/33]CY09.11.2011
CZ09.11.2011
DK09.11.2011
EE09.11.2011
FI09.11.2011
RO09.11.2011
SE09.11.2011
SI09.11.2011
SK09.11.2011
BG09.02.2012
IE15.09.2012
MC30.09.2012
Former [2013/29]CY09.11.2011
CZ09.11.2011
DK09.11.2011
EE09.11.2011
FI09.11.2011
RO09.11.2011
SE09.11.2011
SI09.11.2011
SK09.11.2011
BG09.02.2012
MC30.09.2012
Former [2012/36]CY09.11.2011
CZ09.11.2011
DK09.11.2011
EE09.11.2011
RO09.11.2011
SE09.11.2011
SI09.11.2011
SK09.11.2011
BG09.02.2012
Former [2012/35]CY09.11.2011
CZ09.11.2011
DK09.11.2011
EE09.11.2011
SE09.11.2011
SI09.11.2011
BG09.02.2012
Former [2012/34]CY09.11.2011
CZ09.11.2011
SE09.11.2011
SI09.11.2011
Former [2012/28]CY09.11.2011
SE09.11.2011
SI09.11.2011
Former [2012/24]SE09.11.2011
SI09.11.2011
Cited inInternational search[A]US5965547  (GOODSHIP ALLEN E [GB], et al) [A] * column 1, paragraph 1 * * column 2, paragraphs 2,3 ** column 3, line 56 *;
 [XA]US6255288  (LOESCHORN CAROL A [GB]) [X] 1-13 * column 1 * * column 2, line 49 - line 65 * * column 8, line 32 * * column 10 * * in particular l. 16/17; 64/65 * * example 2 * * claims 1,5,14 * [A] 14-17;
 [XA]  - REID IAN R ET AL, "Intravenous zoledronic acid in postmenopausal women with low bone mineral density", NEW ENGLAND JOURNAL OF MEDICINE, (20020228), vol. 346, no. 9, ISSN 0028-4793, pages 653 - 661, XP009021019 [X] 1-13,17 * the whole document * [A] 14-16

DOI:   http://dx.doi.org/10.1056/NEJMoa011807
 [X]  - SOLOMON C G, "Bisphosphonates and osteoporosis", NEW ENGLAND JOURNAL OF MEDICINE 28 FEB 2002 UNITED STATES, (20020228), vol. 346, no. 9, ISSN 0028-4793, page 642, XP009021021 [X] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1056/NEJM200202283460902
 [A]  - NEED ALLAN G ET AL, "Vitamin D status: Effects on parathyroid hormone and 1,25-dihydroxyvitamin D in postmenopausal women", AMERICAN JOURNAL OF CLINICAL NUTRITION, (200006), vol. 71, no. 6, ISSN 0002-9165, pages 1577 - 1581, XP002261420 [A] 14-17 * abstract * * Discussion *
Examination   - LYLES, KENNETH W. ET AL, "Zoledronic Acid and Clinical Fractures and Mortality after Hip Fractures", NEW ENGLAND JOURNAL OF MEDICINE, (20071101), vol. 357, no. 18, pages 1799 - 1809
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.