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Extract from the Register of European Patents

EP About this file: EP1575990

EP1575990 - Solid phase bound PNA-dimers and their synthesis [Right-click to bookmark this link]
Former [2005/38]METHODS, COMPOSITIONS AND LIBRARIES PERTAINING PNA DIMER AND PNA OLIGOMER SYNTHESIS
[2009/24]
StatusNo opposition filed within time limit
Status updated on  24.09.2010
Database last updated on 28.05.2024
Most recent event   Tooltip19.10.2012Lapse of the patent in a contracting state
New state(s): TR		published on 21.11.2012  [2012/47]
Applicant(s)For all designated states
Life Technologies Corporation
5823 Newton Drive
Carlsbad, CA 92008 / US
[N/P]
Former [2010/21]For all designated states
Life Technologies Corporation
5791 Van Allen Way
Carlsbad, CA 92008 / US
Former [2010/18]For all designated states
Life Technologies Corporation
5791 Van Alley Way
Carlsbad, CA 92008 / US
Former [2009/47]For all designated states
Applera Corporation
Global Headquarters, 301 Merritt 7, P.O. Box 5435
Norwalk, CT 06856-5435 / US
Former [2005/38]For all designated states
Applera Corporation
Global Headquarters, 301 Merritt 7, P.O. Box 5435
Norwalk, CT 06856-5435 / US
Inventor(s)01 / CASALE, Ralph, A.
41 South Chelmsford Road
Wesford, MA 01886 / US
02 / COULL, James, M.
7 Banbury Drive
Westford, MA 01886 / US
03 / DEY, Subhakar
95 Audubon Road
411 Wakefield, MA 01880 / US
04 / KOWALCZYK, Bruce, A.
3849 Bret Harte Drive
Redwood City, CA 94061 / US
05 / GAN, Kevin, Z.
32712 Downieville Street
Union City, CA 94587 / US
 [2005/43]
Former [2005/38]01 / CASALE, Ralph, A.
41 South Chelmsford Road
Wesford, MA 01886 / US
02 / COULL, James, M.
7 Banbury Drive
Westford, MA 01886 / US
03 / DEY, Subhakar
95 Audubon Road
411 Wakefield, MA 01880 / US
Representative(s)Schnappauf, Georg, et al
ZSP Patentanwälte PartG mbB
Hansastraße 32
80686 München / DE
[N/P]
Former [2008/35]Schnappauf, Georg, et al
Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6
81679 München / DE
Former [2005/38]Schnappauf, Georg, et al
Geibelstrasse 6
81679 München / DE
Application number, filing date03755797.205.09.2003
[2005/38]
WO2003US28087
Priority number, dateUS20020409220P08.09.2002         Original published format: US 409220 P
[2005/38]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004022578
Date:18.03.2004
Language:EN
[2004/12]
Type: A2 Application without search report 
No.:EP1575990
Date:21.09.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 18.03.2004 takes the place of the publication of the European patent application.
[2005/38]
Type: B1 Patent specification 
No.:EP1575990
Date:18.11.2009
Language:EN
[2009/47]
Search report(s)International search report - published on:US11.05.2006
(Supplementary) European search report - dispatched on:EP19.03.2007
ClassificationIPC:C07K1/04, C07K14/00
[2009/24]
CPC:
C40B50/14 (EP,US); C07K1/047 (EP,US); C07K9/00 (EP,US);
C40B40/04 (EP,US); C40B80/00 (EP,US); B01J2219/00454 (EP,US);
B01J2219/005 (EP,US); B01J2219/00576 (EP,US); B01J2219/00596 (EP,US);
B01J2219/00605 (EP,US); B01J2219/0061 (EP,US); B01J2219/00612 (EP,US);
B01J2219/00626 (EP,US); B01J2219/00637 (EP,US); B01J2219/00729 (EP,US);
C07B2200/11 (EP,US); C40B40/10 (EP,US); Y02P20/55 (EP,US) (-)
Former IPC [2007/01]C07K1/00, C07K14/00
Former IPC [2005/38]C07K1/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/38]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:Festphasengebundene PNA-Dimere und deren Synthese[2009/24]
English:Solid phase bound PNA-dimers and their synthesis[2009/24]
French:Dimères d'ANP lient en phase solide et leurs synthèse[2009/24]
Former [2005/38]VERFAHREN, ZUSAMMENSETZUNGEN UND BIBLIOTHEKEN FÜR DIE SYNTHESE VON PNA-DIMEREN UND PNA-OLIGOMEREN
Former [2005/38]METHODS, COMPOSITIONS AND LIBRARIES PERTAINING PNA DIMER AND PNA OLIGOMER SYNTHESIS
Former [2005/38]PROCEDES, COMPOSITIONS ET BANQUES SE RAPPORTANT A LA SYNTHESE DE DIMERE ET D'OLIGOMERE D'ANP
Entry into regional phase02.03.2005National basic fee paid 
02.03.2005Search fee paid 
02.03.2005Designation fee(s) paid 
02.03.2005Examination fee paid 
Examination procedure24.03.2004Request for preliminary examination filed
International Preliminary Examining Authority: US
02.03.2005Examination requested  [2005/38]
08.08.2006Amendment by applicant (claims and/or description)
06.07.2007Despatch of a communication from the examining division (Time limit: M04)
08.11.2007Reply to a communication from the examining division
06.05.2008Despatch of a communication from the examining division (Time limit: M04)
04.09.2008Reply to a communication from the examining division
28.05.2009Communication of intention to grant the patent
06.10.2009Fee for grant paid
06.10.2009Fee for publishing/printing paid
Divisional application(s)EP09014354.6  / EP2161276
Opposition(s)19.08.2010No opposition filed within time limit [2010/43]
Fees paidRenewal fee
21.09.2005Renewal fee patent year 03
27.09.2006Renewal fee patent year 04
26.09.2007Renewal fee patent year 05
25.09.2008Renewal fee patent year 06
25.09.2009Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT18.11.2009
BE18.11.2009
CY18.11.2009
CZ18.11.2009
EE18.11.2009
FI18.11.2009
IT18.11.2009
NL18.11.2009
RO18.11.2009
SE18.11.2009
SI18.11.2009
SK18.11.2009
TR18.11.2009
BG18.02.2010
GR19.02.2010
ES28.02.2010
PT18.03.2010
HU19.05.2010
[2012/47]
Former [2012/42]AT18.11.2009
BE18.11.2009
CY18.11.2009
CZ18.11.2009
EE18.11.2009
FI18.11.2009
IT18.11.2009
NL18.11.2009
RO18.11.2009
SE18.11.2009
SI18.11.2009
SK18.11.2009
BG18.02.2010
GR19.02.2010
ES28.02.2010
PT18.03.2010
HU19.05.2010
Former [2011/14]AT18.11.2009
BE18.11.2009
CY18.11.2009
CZ18.11.2009
EE18.11.2009
FI18.11.2009
IT18.11.2009
NL18.11.2009
RO18.11.2009
SE18.11.2009
SI18.11.2009
SK18.11.2009
BG18.02.2010
GR19.02.2010
ES28.02.2010
PT18.03.2010
Former [2010/48]AT18.11.2009
BE18.11.2009
CY18.11.2009
CZ18.11.2009
EE18.11.2009
FI18.11.2009
NL18.11.2009
RO18.11.2009
SE18.11.2009
SI18.11.2009
SK18.11.2009
BG18.02.2010
GR19.02.2010
ES28.02.2010
PT18.03.2010
Former [2010/39]AT18.11.2009
BE18.11.2009
CY18.11.2009
CZ18.11.2009
EE18.11.2009
FI18.11.2009
NL18.11.2009
RO18.11.2009
SE18.11.2009
SI18.11.2009
SK18.11.2009
BG18.02.2010
ES28.02.2010
PT18.03.2010
Former [2010/36]AT18.11.2009
BE18.11.2009
CY18.11.2009
CZ18.11.2009
EE18.11.2009
FI18.11.2009
NL18.11.2009
RO18.11.2009
SE18.11.2009
SI18.11.2009
BG18.02.2010
ES28.02.2010
PT18.03.2010
Former [2010/35]AT18.11.2009
BE18.11.2009
CY18.11.2009
EE18.11.2009
FI18.11.2009
NL18.11.2009
RO18.11.2009
SE18.11.2009
SI18.11.2009
BG18.02.2010
ES28.02.2010
PT18.03.2010
Former [2010/32]AT18.11.2009
BE18.11.2009
CY18.11.2009
FI18.11.2009
NL18.11.2009
SE18.11.2009
SI18.11.2009
ES28.02.2010
PT18.03.2010
Former [2010/31]AT18.11.2009
BE18.11.2009
CY18.11.2009
FI18.11.2009
SE18.11.2009
SI18.11.2009
ES28.02.2010
PT18.03.2010
Former [2010/30]AT18.11.2009
CY18.11.2009
FI18.11.2009
SE18.11.2009
SI18.11.2009
ES28.02.2010
PT18.03.2010
Former [2010/25]CY18.11.2009
FI18.11.2009
SE18.11.2009
SI18.11.2009
ES28.02.2010
PT18.03.2010
Former [2010/23]FI18.11.2009
SE18.11.2009
SI18.11.2009
ES28.02.2010
PT18.03.2010
Former [2010/22]FI18.11.2009
SE18.11.2009
ES28.02.2010
PT18.03.2010
Former [2010/19]ES28.02.2010
Documents cited:Search[Y]WO0033084  (SYNTRIX BIOCHIP INC [US], et al) [Y] 8 * page 80, paragraph L - page 84, paragraph 1; example 6 *;
 [A]  - SEITZ O, "Solid Phase Synthesis of Protected Peptide Nucleic Acids", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, (19990528), vol. 40, no. 22, ISSN 0040-4039, pages 4161 - 4164, XP004164686 [A] * Scheme 4 *

DOI:   http://dx.doi.org/10.1016/S0040-4039(99)00717-0
 [A]  - HYRUP B ET AL, "PEPTIDE NUCLEIC ACIDS (PNA): SYNTHESIS, PROPERTIES AND POTENTIAL APPLICATIONS", BIOORGANIC & MEDICINAL CHEMISTRY, ELSEVIER SCIENCE LTD, GB, (1996), vol. 4, no. 1, ISSN 0968-0896, pages 5 - 23, XP000602327 [A] * compound 34 *

DOI:   http://dx.doi.org/10.1016/0968-0896(95)00171-9
 [X]  - KOVACS G., TIMAR Z., KUPIHAR Z., KELE Z., KOVACS L., "Synthesis and analysis of peptide nucleic acid oligomers using Fmoc/acyl-protected monomers", J. CHEM. SOC., PERKIN TRANS. I, (20020423), pages 1266 - 1270, XP002408946 [X] 1,2,4-8 * compounds 5,8 *

DOI:   http://dx.doi.org/10.1039/b201297a
 [X]  - CAPASSO D ET AL, "Solid phase synthesis of DNA-3'-PNA chimeras by using Bhoc/Fmoc PNA monomers", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (20011112), vol. 57, no. 46, ISSN 0040-4020, pages 9481 - 9486, XP004312081 [X] 1,2,5-8 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0040-4020(01)00944-9
 [XY]  - SEITZ O; KÖHLER O, "Convergent strategies for the attachment of fluorescing reporter groups to peptide nucleic acids in solution and on solid phase.", CHEMISTRY, (20010917), vol. 7, no. 18, pages 3911 - 3925, XP002408947 [X] 1,2,5-7 * Scheme 9 * [Y] 8

DOI:   http://dx.doi.org/10.1002/1521-3765(20010917)7:18<3911::AID-CHEM3911>3.0.CO;2-1
 [A]  - THOMSON S A ET AL, "FMOC MEDIATED SYNTHESIS OF PEPTIDE NUCLEIC ACIDS", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (19950529), vol. 51, no. 22, ISSN 0040-4020, pages 6179 - 6194, XP002030024 [A] 1-8,22-27 * page 6183, paragraph 3 *

DOI:   http://dx.doi.org/10.1016/0040-4020(95)00286-H
 [DA]  - CASALE RALPH; JENSEN IVAR S; EGHOLM MICHAEL, "Synthesis of PNA oligomers by FMOC chemistry", PEPTIDE NUCLEIC ACIDS: PROTOCOLS AND APPLICATIONS, Horizon Scientific Press, P. O. Box 1, Wymondham, Norfolk NR18 0EH, England, UK, (1999), pages 39 - 50, XP008069866 [DA] 1-8,22-27 * the whole document *
 [A]  - SFORZA S; CORRADINI R; GALAVERNA G; DOSSENA A; MARCHELLI R, "The chemistry of peptide nucleic acids", MINERVA BIOTECNOLOGICA, (1999), vol. 11, no. 3, pages 163 - 174, XP008069802 [A] 1-8,22-27 * the whole document *
International search[X]US6261776  (READ J LEIGHTON [US], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.