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Extract from the Register of European Patents

EP About this file: EP1533375

EP1533375 - METHOD OF TRANSFERRING MUTATION INTO TARGET NUCLEIC ACID [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.07.2010
Database last updated on 05.10.2024
Most recent event   Tooltip19.10.2012Lapse of the patent in a contracting state
New state(s): TR		published on 21.11.2012  [2012/47]
Applicant(s)For all designated states
TAKARA BIO INC.
4-1, Seta 3-chome Otsu-shi
Shiga 520-2193 / JP
[2009/38]
Former [2005/21]For all designated states
TAKARA BIO INC.
4-1, Seta 3-chome
Otsu-shi, Shiga 520-2193 / JP
Inventor(s)01 / CAO, Chunyu 402, Hamoparesu-Kusatsu
12-1, Nishishibukawa 2-chome
Kusatsu-shi, Shiga 525-0025 / JP
02 / SAGAWA, Hiroaki
c/o TAKARA BIO INC. 4-1, Seta 3-chome
Otsu-shi, Shiga 520-2193 / JP
03 / KATO, Ikunoshin
TAKARA BIO INC. 4-1 Seta-3-chome
Otsu-chi, Shiga 520-2193 / JP
 [2009/38]
Former [2009/31]01 / CAO, Chunyu 402, Hamoparesu-Kusatsu
12-1, Nishishibukawa 2-chome
Kusatsu-shi, Shiga 525-0025 / JP
02 / SAGAWA, Hiroaki
c/o TAKARA BIO INC. 4-1, Seta 3-chome
Otsu-shi, Shiga 520-2193 / JP
03 / KATO, Ikunoshin
Takara Bio Inc. 4-1 Seta-3-chome
Otsu-chi, Shiga 520-2193 / JP
Former [2008/44]01 / CAO, Chunyu 402, Hamoparesu-Kusatsu
12-1, Nishishibukawa 2-chome
Kusatsu-shi, Shiga 525-0025 / JP
02 / SAGAWA, Hiroaki
6-32, Nishishibukawa 2-chome
Kusatsu-shi, Shiga 525-0025 / JP
03 / KATO, Ikunoshin
Takara Bio Inc. 4-1 Seta-3-chome
Otsu-chi, Shiga 520-2193 / JP
Former [2007/03]01 / CAO, Chunyu 402, Hamoparesu-Kusatsu
12-1, Nishishibukawa 2-chome
Kusatsu-shi, Shiga 525-0025 / JP
02 / SAGAWA, Hiroaki
6-32, Nishishibukawa 2-chome
Kusatsu-shi, Shiga 525-0025 / JP
03 / KATO, Ikunoshin
Takara Bio Inc. 4-1 Seta-3-chome
Uji-shi, Kyoto 611-0028 / JP
Former [2005/21]01 / CAO, Chunyu 402, Hamoparesu-Kusatsu
12-1, Nishishibukawa 2-chome
Kusatsu-shi, Shiga 525-0025 / JP
02 / SAGAWA, Hiroaki
6-32, Nishishibukawa 2-chome
Kusatsu-shi, Shiga 525-0025 / JP
03 / KATO, Ikunoshin
1-1-150, Nanryo-cho
Uji-shi, Kyoto 611-0028 / JP
Representative(s)Schnappauf, Georg, et al
ZSP Patentanwälte PartG mbB
Hansastraße 32
80686 München / DE
[N/P]
Former [2006/10]Schnappauf, Georg, et al
Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6
81679 München / DE
Former [2005/21]Grund, Martin, Dr., et al
Dr. Volker Vossius, Patentanwaltskanzlei, Geibelstrasse 6
81679 München / DE
Application number, filing date03764168.511.07.2003
[2005/21]
WO2003JP08816
Priority number, dateJP2002020488712.07.2002         Original published format: JP 2002204887
JP2003011353418.04.2003         Original published format: JP 2003113534
[2005/21]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004007715
Date:22.01.2004
Language:EN
[2004/04]
Type: A1 Application with search report 
No.:EP1533375
Date:25.05.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 22.01.2004 takes the place of the publication of the European patent application.
[2005/21]
Type: B1 Patent specification 
No.:EP1533375
Date:16.09.2009
Language:EN
[2009/38]
Search report(s)International search report - published on:JP22.01.2004
(Supplementary) European search report - dispatched on:EP15.07.2005
ClassificationIPC:C12N15/09, C12N15/63, C12N15/90, C12Q1/68
[2005/34]
CPC:
C07K14/43595 (EP,US); C12N15/102 (EP,US)
Former IPC [2005/21]C12N15/09, C12Q1/68
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/21]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:VERFAHREN ZUR ÜBERTRAGUNG EINER MUTATION IN EINE ZIELNUKLEINSÄURE[2005/21]
English:METHOD OF TRANSFERRING MUTATION INTO TARGET NUCLEIC ACID[2005/21]
French:PROCEDE DE TRANSFERT DE MUTATION DANS UN ACIDE NUCLEIQUE CIBLE[2005/21]
Entry into regional phase22.12.2004Translation filed 
22.12.2004National basic fee paid 
22.12.2004Search fee paid 
22.12.2004Designation fee(s) paid 
22.12.2004Examination fee paid 
Examination procedure17.12.2003Request for preliminary examination filed
International Preliminary Examining Authority: JP
22.12.2004Examination requested  [2005/21]
28.04.2006Despatch of a communication from the examining division (Time limit: M04)
11.08.2006Reply to a communication from the examining division
29.08.2006Despatch of a communication from the examining division (Time limit: M02)
10.10.2006Reply to a communication from the examining division
09.09.2008Despatch of a communication from the examining division (Time limit: M04)
06.11.2008Reply to a communication from the examining division
30.03.2009Communication of intention to grant the patent
06.07.2009Fee for grant paid
06.07.2009Fee for publishing/printing paid
Opposition(s)17.06.2010No opposition filed within time limit [2010/34]
Fees paidRenewal fee
27.07.2005Renewal fee patent year 03
27.07.2006Renewal fee patent year 04
25.07.2007Renewal fee patent year 05
27.03.2008Renewal fee patent year 06
29.07.2009Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT16.09.2009
BE16.09.2009
BG16.09.2009
CY16.09.2009
CZ16.09.2009
DK16.09.2009
EE16.09.2009
FI16.09.2009
IT16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
TR16.09.2009
GR17.12.2009
ES27.12.2009
PT18.01.2010
HU17.03.2010
[2012/47]
Former [2012/42]AT16.09.2009
BE16.09.2009
BG16.09.2009
CY16.09.2009
CZ16.09.2009
DK16.09.2009
EE16.09.2009
FI16.09.2009
IT16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
GR17.12.2009
ES27.12.2009
PT18.01.2010
HU17.03.2010
Former [2012/41]AT16.09.2009
BE16.09.2009
BG16.09.2009
CY16.09.2009
CZ16.09.2009
DK16.09.2009
EE16.09.2009
FI16.09.2009
IT16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
GR17.12.2009
ES27.12.2009
PT18.01.2010
Former [2011/14]AT16.09.2009
BE16.09.2009
CY16.09.2009
CZ16.09.2009
DK16.09.2009
EE16.09.2009
FI16.09.2009
IT16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
GR17.12.2009
ES27.12.2009
PT18.01.2010
Former [2010/48]AT16.09.2009
BE16.09.2009
CY16.09.2009
CZ16.09.2009
DK16.09.2009
EE16.09.2009
FI16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
GR17.12.2009
ES27.12.2009
PT18.01.2010
Former [2010/35]AT16.09.2009
BE16.09.2009
CY16.09.2009
CZ16.09.2009
DK16.09.2009
EE16.09.2009
FI16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
ES27.12.2009
PT18.01.2010
Former [2010/30]AT16.09.2009
BE16.09.2009
CY16.09.2009
CZ16.09.2009
EE16.09.2009
FI16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
ES27.12.2009
PT18.01.2010
Former [2010/28]BE16.09.2009
CY16.09.2009
CZ16.09.2009
EE16.09.2009
FI16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
ES27.12.2009
PT18.01.2010
Former [2010/23]CY16.09.2009
CZ16.09.2009
EE16.09.2009
FI16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
SK16.09.2009
ES27.12.2009
PT18.01.2010
Former [2010/22]CY16.09.2009
CZ16.09.2009
EE16.09.2009
FI16.09.2009
NL16.09.2009
RO16.09.2009
SE16.09.2009
SI16.09.2009
ES27.12.2009
PT18.01.2010
Former [2010/20]CY16.09.2009
EE16.09.2009
FI16.09.2009
NL16.09.2009
SE16.09.2009
SI16.09.2009
ES27.12.2009
Former [2010/19]CY16.09.2009
FI16.09.2009
NL16.09.2009
SE16.09.2009
SI16.09.2009
ES27.12.2009
Former [2010/16]CY16.09.2009
FI16.09.2009
NL16.09.2009
SE16.09.2009
SI16.09.2009
Former [2010/11]FI16.09.2009
NL16.09.2009
SE16.09.2009
SI16.09.2009
Former [2010/10]FI16.09.2009
NL16.09.2009
SE16.09.2009
Former [2010/09]FI16.09.2009
SE16.09.2009
Documents cited:Search[X]WO0149844  (UNIV RUTGERS [US], et al) [X] 11,14,15 * figures 4-6; claim 7 *;
 [X]  - PICCIN A ET AL, Efficient and heritable functional knock-out of an adult phenotype in Drosophila using a GAL4-driven hairpin RNA incorporating a heterologous spacer., NUCLEIC ACIDS RESEARCH. 15 JUN 2001, VOL. 29, NR. 12, PAGE(S) E55 - E55, (20010615), ISSN 1362-4962, XP002334559 [X] 11,14,15 * figure 1 *

DOI:   http://dx.doi.org/10.1093/nar/29.12.e55
 [X]  - WALDMAN ALAN S ET AL, "Long inverted repeats are an at-risk motif for recombination in mammalian cells.", GENETICS, (199912), vol. 153, no. 4, ISSN 0016-6731, pages 1873 - 1883, XP002334555 [X] 11,14,15 * figure 1 *
 [A]  - BZYMEK MALGORZATA ET AL, "Evidence for two mechanisms of palindrome-stimulated deletion in Escherichia coli: Single-strand annealing and replication slipped mispairing", GENETICS, (200106), vol. 158, no. 2, ISSN 0016-6731, pages 527 - 540, XP002334556 [A] * figure 7 *
 [A]  - LOBACHEV KIRILL S ET AL, "Factors affecting inverted repeat stimulation of recombination and deletion in Saccharomyces cerevisiae", GENETICS, (199804), vol. 148, no. 4, ISSN 0016-6731, pages 1507 - 1524, XP002334557 [A] * abstract *
International search[XP]WO0073478  (UNIV WASHINGTON [US], et al);
 [X]  - STEINWAERDER D.S. ET AL., "Generation of adenovirus vectors devoid of all viral genes by recombination between inverted repeats", J. VIROL., (1999), vol. 73, no. 11, pages 9303 - 9313, XP000914992
 [Y]  - GARCIA-BUSTOS J. ET AL., "Nuclear protein localization", BIOCHIM. BIOPHYS. ACTA, (1991), vol. 1071, no. 1, pages 83 - 101, XP002113641

DOI:   http://dx.doi.org/10.1016/0304-4157(91)90013-M
 [A]  - RECCHIA A. ET AL., "Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector", PROC. NATL. ACAD. SCI. USA, (1999), vol. 96, no. 6, pages 2615 - 2620, XP002152917

DOI:   http://dx.doi.org/10.1073/pnas.96.6.2615
ExaminationUS5643762
    - ELBASHIR ET AL, "Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate", EMBO J, (20011203), vol. 20, no. 23, pages 6877 - 6888
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