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Extract from the Register of European Patents

EP About this file: EP1525306

EP1525306 - THREE-DIMENSIONAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  23.07.2010
Database last updated on 24.08.2024
Most recent event   Tooltip23.07.2010Application deemed to be withdrawnpublished on 25.08.2010  [2010/34]
Applicant(s)For all designated states
Mitsubishi Tanabe Pharma Corporation
2-10, Dosho-machi 3-chome Chuo-ku Osaka-shi
Osaka 541-8505 / JP
[2007/49]
Former [2005/17]For all designated states
TANABE SEIYAKU CO., LTD.
2-10, Dosho-machi 3-chome
Chuo-ku, Osaka-shi, Osaka 541-8505 / JP
Inventor(s)01 / HIRAMATSU, Hajime, c/o Tanabe Seiyaku Co., Ltd.
2-10, Dosho-machi 3-chome, Chuo-ku
Osaka-shi, Osaka 541-8505 / JP
02 / KYONO, Kiyoshi, c/o Tanabe Seiyaku Co., Ltd.
2-10, Dosho-machi 3-chome, Chuo-ku
Osaka-shi, Osaka 541-8505 / JP
03 / SHIMA, Hideaki
1-26-1, Shirakawadai
Suma-ku, Kobe-shi, Hyogo 654-0103 / JP
04 / SUGIYAMA, Shigeru
1450-15, Tsutsui-cho
Yamatokoriyama-shi, Nara 639-1123 / JP
 [2005/17]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastrasse 30
81925 München / DE
[N/P]
Former [2005/17]HOFFMANN - EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date03771375.728.07.2003
[2005/17]
WO2003JP09523
Priority number, dateUS20020398761P29.07.2002         Original published format: US 398761 P
[2005/17]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004011640
Date:05.02.2004
Language:EN
[2004/06]
Type: A1 Application with search report 
No.:EP1525306
Date:27.04.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 05.02.2004 takes the place of the publication of the European patent application.
[2005/17]
Search report(s)International search report - published on:EP05.02.2004
ClassificationIPC:C12N9/48, C07K14/705, G01N23/20, G01N33/573
[2005/17]
CPC:
C07K14/70596 (EP,US); A61P19/02 (EP); A61P25/00 (EP);
A61P29/00 (EP); A61P3/10 (EP); A61P31/18 (EP);
A61P35/00 (EP); A61P37/02 (EP); A61P43/00 (EP);
C12N9/48 (EP,US); C12Y304/14005 (EP,US); C07K2299/00 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/17]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:DREIDIMENSIONALE STRUKTUR DER DIPEPTIDYL-PEPTIDASE IV[2005/17]
English:THREE-DIMENSIONAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV[2005/17]
French:STRUCTURE TRIDIMENSIONNELLE DE LA DIPEPTIDYLPEPTIDASE IV[2005/17]
Entry into regional phase10.02.2005National basic fee paid 
10.02.2005Designation fee(s) paid 
10.02.2005Examination fee paid 
Examination procedure22.08.2003Request for preliminary examination filed
International Preliminary Examining Authority: EP
10.02.2005Examination requested  [2005/17]
20.07.2007Despatch of a communication from the examining division (Time limit: M06)
21.01.2008Reply to a communication from the examining division
04.03.2008Despatch of a communication from the examining division (Time limit: M02)
30.04.2008Reply to a communication from the examining division
11.06.2008Despatch of a communication from the examining division (Time limit: M02)
29.07.2008Reply to a communication from the examining division
24.02.2009Despatch of a communication from the examining division (Time limit: M02)
17.04.2009Reply to a communication from the examining division
15.10.2009Despatch of a communication from the examining division (Time limit: M04)
26.02.2010Application deemed to be withdrawn, date of legal effect  [2010/34]
07.04.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2010/34]
Fees paidRenewal fee
25.07.2005Renewal fee patent year 03
26.07.2006Renewal fee patent year 04
17.07.2007Renewal fee patent year 05
25.07.2008Renewal fee patent year 06
16.07.2009Renewal fee patent year 07
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Cited inInternational search[XY]  - KABASHIMA T ET AL, "DIPEPTIDYL PEPTIDASE IV FROM XANTHAMONAS MALTOPHILIA: SEQUENCING AND EXPRESSION OF THE ENZYME GENE AND CHARACTERIZATION OF THE EXPRESSED ENZYME", JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOCIETY, TOKYO, JP, (199612), vol. 120, no. 6, ISSN 0021-924X, pages 1111 - 1117, XP000973151 [X] 1,2,6 * figure 4 * * the whole document * [Y] 3-5,14-20
 [Y]  - ABBOTT CATHERINE A ET AL, "Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted beta propeller domain", EUROPEAN JOURNAL OF BIOCHEMISTRY, (199912), vol. 266, no. 3, ISSN 0014-2956, pages 798 - 810, XP002261851 [Y] 3-5,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1046/j.1432-1327.1999.00902.x
 [Y]  - LAMBEIR A-M ET AL, "A prediction of DPP IV/CD26 domain structure from a physico-chemical investigation of dipeptidyl peptidase IV (CD26) from human seminal plasma", BIOCHIMICA ET BIOPHYSICA ACTA. PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, ELSEVIER, AMSTERDAM,, NL, (19970718), vol. 1340, no. 2, ISSN 0167-4838, pages 215 - 226, XP004281676 [Y] 3-5,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0167-4838(97)00045-9
 [Y]  - MEDRANO F J ET AL, "Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: A prototype for the prolyl oligopeptidase family", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, (19980102), vol. 17, no. 1, ISSN 0261-4189, pages 1 - 9, XP002261745 [Y] 3-5,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1093/emboj/17.1.1
 [A]  - POLGAR L, "The prolyl oligopeptidase family", CMLS CELLULAR AND MOLECULAR LIFE SCIENCES, BIRKHAUSER VERLAG, BASEL, CH, (200202), vol. 59, no. 2, ISSN 1420-682X, pages 349 - 362, XP002219152 [A] 1-6,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1007/s00018-002-8427-5
 [A]  - FULOP V ET AL, "Prolyl oligopeptidase: An unusual beta-propeller domain regulates proteolysis", CELL, CELL PRESS, CAMBRIDGE, NA, US, (19980724), vol. 94, no. 2, ISSN 0092-8674, pages 161 - 170, XP002221331 [A] 1-6,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0092-8674(00)81416-6
 [A]  - AUGUSTYNS K ET AL, "THE UNIQUE PROPERTIES OF DIPEPTIDYL-PEPTIDASE IV (DPP IV/CD26) AND THE THERAPEUTIC POTENTIAL OF DPP IV INHIBITORS", CURRENT MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBLISHERS BV, BE, (1999), vol. 6, no. 4, ISSN 0929-8673, pages 311 - 327, XP000870290 [A] 1-6,14-20 * the whole document *
 [PX]  - ENGEL MICHAEL ET AL, "The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, April 29, 2003, (20030429), vol. 100, no. 9, ISSN 0027-8424 (ISSN print), pages 5063 - 5068, XP002261746 [PX] 1-6,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.0230620100
 [PX]  - RASMUSSEN HANNE B ET AL, "Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog.", NATURE STRUCTURAL BIOLOGY, (200301), vol. 10, no. 1, ISSN 1072-8368 (ISSN print), pages 19 - 25, XP001168693 [PX] 1-6,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1038/nsb882
 [PX]  - HIRAMATSU HAJIME ET AL, "The structure and function of human dipeptidyl peptidase IV, possessing a unique eight-bladed beta-propeller fold.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (20030321), vol. 302, no. 4, ISSN 0006-291X, pages 849 - 854, XP002261748 [PX] 1-6,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0006-291X(03)00258-4
 [PX]  - OEFNER CHRISTIAN ET AL, "High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)- acetyl]-2-cyano-(S)-pyrrolidine.", ACTA CRYSTALLOGRAPHICA. SECTION D, BIOLOGICAL CRYSTALLOGRAPHY. DENMARK JUL 2003, (200307), vol. 59, no. Pt 7, ISSN 0907-4449, pages 1206 - 1212, XP008024791 [PX] 1-6,14-20 * the whole document *

DOI:   http://dx.doi.org/10.1107/S0907444903010059
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