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Extract from the Register of European Patents

EP About this file: EP1627042

EP1627042 - MAP2K6 AS MODIFIER OF BRANCHING MORPHOGENENSIS AND METHODS OF USE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  28.03.2008
Database last updated on 06.07.2024
Most recent event   Tooltip28.03.2008Application deemed to be withdrawnpublished on 30.04.2008  [2008/18]
Applicant(s)For all designated states
Exelixis, Inc.
170 Harbor Way, P.O. Box 511
South San Francisco, CA 94083-0511 / US
[2006/08]
Inventor(s)01 / PLOWMAN, Gregory, D.
35 Winding Way
San Carlos, CA 94070 / US
02 / KARIM, Felix, D.
732 Laurel Drive
Walnut Creek, CA 94596 / US
03 / SWIMMER, Candace
360 Arkansas Street
San Francisco, CA 94107 / US
04 / HABECK, Hinrich, Alexander
Gertrud-Baeumer-Str. 74
72074 Tuebingen / DE
05 / KOBLIZEK, Thomas, I.
Gechtstr. 31
72074 Tuebingen / DE
06 / SCHULTE-MERKER, Stefan
Kronenstr. 17
72070 Tuebingen / DE
07 / LANGHEINRICH, Ulrike
Derendinger Str. 104
72072 Tuebingen / DE
08 / STOTT, Gordon, Mark
Quenstedtstrasse 24
72076 Tuebingen / DE
09 / TROWE, Torsten
Im Waegner 23
72070 Tuebingen / DE
10 / VOGEL, Andreas, Michael
Linsenbergstrasse 12
72074 Tuebingen / DE
11 / ODENTHAL, Joerg, Heinrich
Otto-Erbe-Weg 18
72070 Tuebingen / DE
12 / SCHEEL, Jochen, Konrad
Eduard-Spranger-Strasse 72
72076 Tuebingen / DE
13 / WILL, Torsten, Tilmann
Eichenweg 2
72076 Tuebingen / DE
14 / JIN, Yisheng
192 36th Avenue, Apt.B
San Mateo, CA 94403 / US
 [2006/08]
Representative(s)Main, Malcolm Charles, et al
Murgitroyd & Company
Scotland House
165-169 Scotland Street
Glasgow G5 8PL / GB
[N/P]
Former [2006/08]Main, Malcolm Charles, et al
Murgitroyd & Company Scotland House 165-169 Scotland Street
Glasgow G5 8PL / GB
Application number, filing date03779165.422.10.2003
[2006/08]
WO2003US33489
Priority number, dateUS20020420554P23.10.2002         Original published format: US 420554 P
[2006/08]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004037986
Date:06.05.2004
Language:EN
[2004/19]
Type: A2 Application without search report 
No.:EP1627042
Date:22.02.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 06.05.2004 takes the place of the publication of the European patent application.
[2006/08]
Search report(s)International search report - published on:US16.02.2006
(Supplementary) European search report - dispatched on:EP02.08.2007
ClassificationIPC:G01N33/50
[2006/27]
CPC:
G01N33/5088 (EP,US); A61P35/00 (EP); A61P43/00 (EP);
A61P9/00 (EP); C12N9/1205 (EP,US); C12Q1/485 (EP,US);
G01N33/5011 (EP,US); G01N33/57438 (EP,US); G01N33/57496 (EP,US);
A01K2217/05 (EP,US) (-)
Former IPC [2006/08]C12N1/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2006/08]
Extension statesAL25.03.2005
LT25.03.2005
LV25.03.2005
MK25.03.2005
TitleGerman:MAP2K6 ALS MODIFIKATOR DER VERZWEIGUNGSMORPHOGENESE UND VERWENDUNGSVERFAHREN[2006/08]
English:MAP2K6 AS MODIFIER OF BRANCHING MORPHOGENENSIS AND METHODS OF USE[2006/08]
French:MAP2K6 UTILISE COMME MODIFICATEUR DE MORPHOGENESE RAMIFIEE ET PROCEDES D'UTILISATION CORRESPONDANTS[2006/08]
Entry into regional phase25.03.2005National basic fee paid 
25.03.2005Search fee paid 
25.03.2005Designation fee(s) paid 
25.03.2005Examination fee paid 
Examination procedure25.03.2005Examination requested  [2006/08]
02.11.2007Application deemed to be withdrawn, date of legal effect  [2008/18]
13.12.2007Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2008/18]
Fees paidRenewal fee
12.10.2005Renewal fee patent year 03
12.10.2006Renewal fee patent year 04
12.10.2007Renewal fee patent year 05
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Documents cited:Search[XY]EP1174129  (ZENNER HANS PETER PROF DR MED [DE], et al) [X] 26-30 * abstract * * paragraph [0010] * [Y] 1-25;
 [Y]  - HARRIS V K ET AL, "Induction of the angiogenic modulator fibroblast growth factor-binding protein by epidermal growth factor is mediated through both MEK/ERK and p38 signal transduction pathways", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, (20000414), vol. 275, no. 15, ISSN 0021-9258, pages 10802 - 10811, XP002904757 [Y] 1-30 * abstract * * page 10808, column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1074/jbc.275.15.10802
 [Y]  - SODHI AKRIT ET AL, "The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha", CANCER RESEARCH, (20000901), vol. 60, no. 17, ISSN 0008-5472, pages 4873 - 4880, XP002443609 [Y] 1-30 * abstract * * page 4876, column 1, paragraph 2 *
 [A]  - CHAN J ET AL, "Dissection of angiogenic signaling in zebrafish using a chemical genetic approach", CANCER CELL, XX, US, (200204), vol. 1, no. 3, ISSN 1535-6108, pages 257 - 267, XP002258881 [A] 1-30 * the whole document *

DOI:   http://dx.doi.org/10.1016/S1535-6108(02)00042-9
International search[A]US6033910  (MONIA BRETT P [US], et al);
 [X]  - WONG ET AL, "Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium", MEDLINE, Database accession no. 2001489213
    [ ] - GYNECOLOGIC ONCOLOGY, (200108), vol. 82, pages 305 - 311
 [X]  - LUO ET AL, "Human prostate cancer and benign prostatic hyperplasia: molecular dissection by gene expression profiling", CANCER RESEARCH, (20010615), vol. 15, pages 4683 - 4688, XP002251016
 [X]  - KOOCHEKPOUR ET AL, "The von-Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasionand branching morphpogenesis in renal carcinoma cells", MOLECULAR ANDN CELLULAR BIOLOGY, (199909), vol. 19, pages 5902 - 5912
 [X]  - SALVUCCI ET AL, "Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1", BLOOD, (20020415), vol. 99, doi:doi:10.1182/blood.V99.8.2703, pages 2703 - 2711, XP002481675

DOI:   http://dx.doi.org/10.1182/blood.V99.8.2703
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.