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Extract from the Register of European Patents

EP About this file: EP1579220

EP1579220 - USE OF NICOTINAMIDE N-METHYLTRANSFERASE AS A MARKER FOR COLORECTAL CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.06.2008
Database last updated on 19.10.2024
Most recent event   Tooltip18.09.2009Lapse of the patent in a contracting state
New state(s): HU, TR		published on 21.10.2009  [2009/43]
Applicant(s)For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT  RO  SE  SI  SK  TR 
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[N/P]
Former [2005/39]For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HU  IE  IT  LI  LU  MC  NL  PT  RO  SE  SI  SK  TR 
F. HOFFMANN-LA ROCHE AG
Grenzacherstrasse 124
4070 Basel / CH
Inventor(s)01 / BERNDT, Peter
Mittlere Strasse 138
CH-4056 Basel / CH
02 / HAGMANN, Marie-Luise
Saalangerstrasse 42
82377 Penzberg / DE
03 / LANGEN, Hanno
Im Wolfischbühl 27/4
79585 Steinen / DE
04 / PALME, Stefan
Hochfeldstrasse 19
82377 Penzberg / DE
05 / ROESSLER, Markus
Eichenstrasse 9a
82110 Germering / DE
06 / ROLLINGER, Wolfgang
Kaiser-Heinrich-Strasse 10
82398 Polling / DE
07 / TACKE, Michael
Hansastrasse 110
81373 München / DE
08 / ZOLG, Werner
Sportplatzweg 4A
82362 Weilheim / DE
09 / KARL, Johann
Bert-Schratzlseerstrasse 7
82380 Peissenberg / DE
10 / KOTT, Theresa
Aidenbachstrasse 74
81379 München / DE
 [2005/39]
Application number, filing date03813582.819.12.2003
[2005/39]
WO2003EP14583
Priority number, dateEP2002002871520.12.2002         Original published format: EP 02028715
[2005/39]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004057336
Date:08.07.2004
Language:EN
[2004/28]
Type: A2 Application without search report 
No.:EP1579220
Date:28.09.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 08.07.2004 takes the place of the publication of the European patent application.
[2005/39]
Type: B1 Patent specification 
No.:EP1579220
Date:15.08.2007
Language:EN
[2007/33]
Search report(s)International search report - published on:EP20.01.2005
ClassificationIPC:G01N33/574
[2005/39]
CPC:
G01N33/57419 (EP,KR,US); C12Q1/48 (EP,KR,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/39]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:VERWENDUNG VON NICOTINAMIDE N-METHYLTRANSFERASE ZUR DIAGNOSE VON KOLOREKTALEM KREBS[2005/39]
English:USE OF NICOTINAMIDE N-METHYLTRANSFERASE AS A MARKER FOR COLORECTAL CANCER[2005/39]
French:UTILISATION DE NICOTINAMIDE N-METHYLTRANSFERASE COMME MARQUEUR DU CANCER COLORECTAL[2005/39]
Entry into regional phase20.07.2005National basic fee paid 
20.07.2005Designation fee(s) paid 
20.07.2005Examination fee paid 
Examination procedure17.07.2004Request for preliminary examination filed
International Preliminary Examining Authority: EP
20.07.2005Examination requested  [2005/39]
02.01.2007Communication of intention to grant the patent
28.04.2007Fee for grant paid
28.04.2007Fee for publishing/printing paid
Opposition(s)16.05.2008No opposition filed within time limit [2008/30]
Fees paidRenewal fee
05.12.2005Renewal fee patent year 03
05.12.2006Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipBE15.08.2007
CY15.08.2007
CZ15.08.2007
DK15.08.2007
EE15.08.2007
FI15.08.2007
NL15.08.2007
RO15.08.2007
SI15.08.2007
SK15.08.2007
TR15.08.2007
BG15.11.2007
SE15.11.2007
GR16.11.2007
IE19.12.2007
LU19.12.2007
MC31.12.2007
PT15.01.2008
HU16.02.2008
[2009/43]
Former [2009/40]BE15.08.2007
CY15.08.2007
CZ15.08.2007
DK15.08.2007
EE15.08.2007
FI15.08.2007
NL15.08.2007
RO15.08.2007
SI15.08.2007
SK15.08.2007
BG15.11.2007
SE15.11.2007
GR16.11.2007
IE19.12.2007
LU19.12.2007
MC31.12.2007
PT15.01.2008
Former [2009/35]BE15.08.2007
CY15.08.2007
CZ15.08.2007
DK15.08.2007
EE15.08.2007
FI15.08.2007
NL15.08.2007
RO15.08.2007
SI15.08.2007
SK15.08.2007
BG15.11.2007
SE15.11.2007
GR16.11.2007
IE19.12.2007
MC31.12.2007
PT15.01.2008
Former [2009/29]BE15.08.2007
CZ15.08.2007
DK15.08.2007
EE15.08.2007
FI15.08.2007
NL15.08.2007
RO15.08.2007
SI15.08.2007
SK15.08.2007
BG15.11.2007
SE15.11.2007
GR16.11.2007
IE19.12.2007
MC31.12.2007
PT15.01.2008
Former [2009/11]BE15.08.2007
CZ15.08.2007
DK15.08.2007
EE15.08.2007
FI15.08.2007
NL15.08.2007
RO15.08.2007
SK15.08.2007
BG15.11.2007
SE15.11.2007
GR16.11.2007
IE19.12.2007
MC31.12.2007
PT15.01.2008
Former [2008/48]BE15.08.2007
CZ15.08.2007
DK15.08.2007
FI15.08.2007
NL15.08.2007
RO15.08.2007
SK15.08.2007
BG15.11.2007
SE15.11.2007
GR16.11.2007
IE19.12.2007
MC31.12.2007
PT15.01.2008
Former [2008/33]BE15.08.2007
CZ15.08.2007
DK15.08.2007
FI15.08.2007
NL15.08.2007
RO15.08.2007
SK15.08.2007
BG15.11.2007
SE15.11.2007
GR16.11.2007
MC31.12.2007
PT15.01.2008
Former [2008/28]BE15.08.2007
CZ15.08.2007
DK15.08.2007
FI15.08.2007
NL15.08.2007
RO15.08.2007
SK15.08.2007
BG15.11.2007
SE15.11.2007
GR16.11.2007
PT15.01.2008
Former [2008/25]BE15.08.2007
CZ15.08.2007
DK15.08.2007
FI15.08.2007
NL15.08.2007
SK15.08.2007
BG15.11.2007
GR16.11.2007
PT15.01.2008
Former [2008/22]BE15.08.2007
DK15.08.2007
FI15.08.2007
NL15.08.2007
BG15.11.2007
GR16.11.2007
Former [2008/21]BE15.08.2007
FI15.08.2007
NL15.08.2007
BG15.11.2007
GR16.11.2007
Former [2008/11]FI15.08.2007
NL15.08.2007
BG15.11.2007
Former [2008/09]NL15.08.2007
BG15.11.2007
Cited inInternational search[A]WO02090512  (GENAISSANCE PHARMACEUTICALS [US], et al) [A] 1-10 * the whole document *;
 [X]  - AOYAMA KOJI ET AL, "Nicotinamide-N-methyltransferase is higher in the lumbar cerebrospinal fluid of patients with Parkinson's disease.", NEUROSCIENCE LETTERS, (20010126), vol. 298, no. 1, ISSN 0304-3940, pages 78 - 80, XP002237184 [X] 10 * abstract *

DOI:   http://dx.doi.org/10.1016/S0304-3940(00)01723-7
 [DA]  - BRUNAGEL GISELA ET AL, "Identification of nuclear matrix protein alterations associated with human colon cancer.", CANCER RESEARCH, April 15, 2002, (20020415), vol. 62, no. 8, ISSN 0008-5472, pages 2437 - 2442, XP002237185 [DA] 1-10 * abstract *
 [DA]  - OKAMURA ATSUSHI ET AL, "Increased hepatic nicotinamide N-methyltransferase activity as a marker of cancer cachexia in mice bearing colon 26 adenocarcinoma.", JAPANESE JOURNAL OF CANCER RESEARCH, (199806), vol. 89, no. 6, ISSN 0910-5050, pages 649 - 656, XP009008878 [DA] 1-10 * abstract *
 [DA]  - AKSOY SAIME ET AL, "Human liver nicotinamide N-methyltransferase: cDNA cloning, expression, and biochemical characterization.", JOURNAL OF BIOLOGICAL CHEMISTRY, (1994), vol. 269, no. 20, ISSN 0021-9258, pages 14835 - 14840, XP002237186 [DA] 1-10 * the whole document *
 [A]  - DE MARZO A M ET AL, "Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis.", CANCER RESEARCH. UNITED STATES 15 AUG 1999, (19990815), vol. 59, no. 16, ISSN 0008-5472, pages 3855 - 3860, XP002237187 [A] 1-10 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.