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Extract from the Register of European Patents

EP About this file: EP1568368

EP1568368 - Pharmaceutical combination comprising a CDK inhibitor and a VEGF receptor inhibitor [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  25.01.2008
Database last updated on 05.10.2024
Most recent event   Tooltip25.01.2008Application deemed to be withdrawnpublished on 27.02.2008  [2008/09]
Applicant(s)For all designated states
Bayer Schering Pharma Aktiengesellschaft
Müllerstrasse 178
13353 Berlin / DE
[2007/19]
Former [2007/15]For all designated states
Bayer Schering Pharma AG
Müllerstrasse 178
13353 Berlin / DE
Former [2005/35]For all designated states
Schering Aktiengesellschaft
Müllerstrasse 178
13342 Berlin / DE
Inventor(s)01 / Siemeister, Gerhard
Reimerswalder Steig 26
13503 Berlin / DE
 [2005/35]
Application number, filing date04090071.426.02.2004
[2005/35]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1568368
Date:31.08.2005
Language:EN
[2005/35]
Search report(s)(Supplementary) European search report - dispatched on:EP23.11.2004
ClassificationIPC:A61K31/44, A61K31/427, A61K31/4439, A61K31/517, A61P35/00
[2005/35]
CPC:
A61K45/06 (EP); A61K31/427 (EP); A61K31/44 (EP);
A61K31/4439 (EP); A61K31/517 (EP); A61P35/00 (EP);
Y02A50/30 (EP) (-)
C-Set:
A61K31/427, A61K2300/00 (EP);
A61K31/4439, A61K2300/00 (EP);
A61K31/44, A61K2300/00 (EP);
A61K31/517, A61K2300/00 (EP)
Designated contracting statesAT [2006/20]
Former [2005/35]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Pharmazeutische Kombination enthaltend einen CDK Inhibitoren und einen VEGF Rezeptor Inhibitoren[2005/35]
English:Pharmaceutical combination comprising a CDK inhibitor and a VEGF receptor inhibitor[2005/35]
French:Combinaison pharmaceutique comprenant un inhibiteur de CDK et un inhibiteur du recepteur VEGF[2005/35]
Examination procedure26.02.2004Examination requested  [2005/35]
17.06.2004Loss of particular rights, legal effect: Claims
23.07.2004Despatch of communication of loss of particular rights: Claims {1}
01.02.2006Loss of particular rights, legal effect: designated state(s)
03.07.2006Despatch of communication of loss of particular rights: designated state(s) BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR
18.06.2007Despatch of a communication from the examining division (Time limit: M04)
01.09.2007Application deemed to be withdrawn, date of legal effect  [2008/09]
15.10.2007Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2008/09]
Fees paidRenewal fee
18.01.2006Renewal fee patent year 03
Penalty fee
Penalty fee Rule 85a EPC 1973
06.04.2006BE   M01   Not yet paid
06.04.2006BG   M01   Not yet paid
06.04.2006CH   M01   Not yet paid
06.04.2006CY   M01   Not yet paid
06.04.2006CZ   M01   Not yet paid
06.04.2006DE   M01   Not yet paid
06.04.2006DK   M01   Not yet paid
06.04.2006EE   M01   Not yet paid
06.04.2006ES   M01   Not yet paid
06.04.2006FI   M01   Not yet paid
06.04.2006FR   M01   Not yet paid
06.04.2006GB   M01   Not yet paid
06.04.2006GR   M01   Not yet paid
06.04.2006HU   M01   Not yet paid
06.04.2006IE   M01   Not yet paid
06.04.2006IT   M01   Not yet paid
06.04.2006LU   M01   Not yet paid
06.04.2006MC   M01   Not yet paid
06.04.2006NL   M01   Not yet paid
06.04.2006PT   M01   Not yet paid
06.04.2006RO   M01   Not yet paid
06.04.2006SE   M01   Not yet paid
06.04.2006SI   M01   Not yet paid
06.04.2006SK   M01   Not yet paid
06.04.2006TR   M01   Not yet paid
Additional fee for renewal fee
28.02.200704   M06   Not yet paid
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Documents cited:Search[DY]WO9835958  (CIBA GEIGY AG [CH], et al) [DY] 1-10* the whole document *;
 [DY]WO9924416  (SQUIBB BRISTOL MYERS CO [US]) [DY] 1-10 * the whole document *;
 [DY]WO0027819  (SCHERING AG [DE], et al) [DY] 1-10 * the whole document *;
 [DY]WO0144217  (BRISTOL MYERS SQUIBB CO [US], et al) [DY] 1-10 * the whole document *;
 [DY]WO03040102  (NOVARTIS AG [CH], et al) [DY] 1-10 * the whole document *;
 [PY]  - MISRA RAJ N ET AL, "N-(cycloalkylamino)acyl-2-aminothiazole inhibitors of cyclin-dependent kinase 2. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thi azolyl]-4- piperidinecarboxamide (BMS-387032), a highly efficacious and selective antitumor agent.", JOURNAL OF MEDICINAL CHEMISTRY. 25 MAR 2004, (20040325), vol. 47, no. 7, ISSN 0022-2623, pages 1719 - 1728, XP002302339 [PY] 1-10 * abstract * * table 1 * * table 3 * * scheme 2a *

DOI:   http://dx.doi.org/10.1021/jm0305568
 [Y]  - SENDEROWICZ ADRIAN M, "Small-molecule cyclin-dependent kinase modulators.", ONCOGENE, (20030929), vol. 22, no. 42, ISSN 0950-9232, pages 6609 - 6620, XP002302340 [Y] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1038/sj.onc.1206954
 [Y]  - BOLD G ET AL, "New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis.", JOURNAL OF MEDICINAL CHEMISTRY. 15 JUN 2000, (20000615), vol. 43, no. 12, ISSN 0022-2623, pages 2310 - 2323, XP002302341 [Y] 1-10 * chart 1, compound CGP 79787D * * abstract * * page 2312, column R, paragraph 2 * * page 2313, column R, paragraph 2 *

DOI:   http://dx.doi.org/10.1021/jm9909443
 [Y]  - WOOD J M ET AL, "PTK787/ZK 222584, A NOVEL AND POTENT INHIBITOR OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR TYROSINE KINASES, IMPAIRS VASCULAR ENDOTHELIAL GROWTH FACTOR-INDUCED RESPONSES AND TUMOR GROWTH AFTER ORAL ADMINISTRATION", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, (20000415), vol. 60, no. 8, ISSN 0008-5472, pages 2178 - 2189, XP000971163 [Y] 1-10 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.