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Extract from the Register of European Patents

EP About this file: EP1591450

EP1591450 - CONJUGATE FOR RETENTION IN BLOOD AND CANCER TISSUE-SPECIFIC DRUG DELIVERY [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  12.09.2008
Database last updated on 05.10.2024
Most recent event   Tooltip12.09.2008Refusal of applicationpublished on 15.10.2008  [2008/42]
Applicant(s)For all designated states
Astellas Pharma Inc.
3-11, Nihonbashi-Honcho 2-chome, Chuo-ku
Tokyo 103-8411 / JP
[2008/24]
Former [2005/44]For all designated states
YAMANOUCHI PHARMACEUTICAL CO. LTD.
No. 3-11 Nihonbashi-Honcho, 2-chome Chuo-ku
Tokyo 103-8411 / JP
Inventor(s)01 / MAEDA, Atsushi, c/o Astellas Pharma Inc.
3-11, Nihonbashi-Honcho 2-chome, Chuo-ku
Tokyo 103-8411 / JP
02 / TAKAGI, Akira, c/o Astellas Pharma Inc.
3-11, Nihonbashi-Honcho 2-chome, Chuo-ku
Tokyo 103-8411 / JP
03 / SAITO, Katsumi, c/o Astellas Pharma Inc.
3-11, Nihonbashi-Honcho 2-chome, Chuo-ku
Tokyo 103-8411 / JP
04 / YAMASHITA, Noboru, c/o Astellas Pharma Inc.
3-11, Nihonbashi-Honcho 2-chome, Chuo-ku
Tokyo 103-8411 / JP
05 / YOSHIOKA, Tatsunobu, c/o Astellas Pharma Inc.
3-11, Nihonbashi-Honcho 2-chome, Chuo-ku
Tokyo 103-8411 / JP
 [2005/44]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastrasse 30
81925 München / DE
[N/P]
Former [2005/44]HOFFMANN EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date04701116.809.01.2004
[2005/44]
WO2004JP00104
Priority number, dateUS20030439560P10.01.2003         Original published format: US 439560 P
[2005/44]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004063216
Date:29.07.2004
Language:EN
[2004/31]
Type: A1 Application with search report 
No.:EP1591450
Date:02.11.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 29.07.2004 takes the place of the publication of the European patent application.
[2005/44]
Search report(s)International search report - published on:JP29.07.2004
(Supplementary) European search report - dispatched on:EP31.03.2006
ClassificationIPC:C07K7/06, A61K9/127, A61K47/42, A61K47/48
[2006/20]
CPC:
C07K7/06 (EP); A61K47/6907 (EP); A61K47/6911 (EP);
A61K9/1271 (EP); A61P29/00 (EP); Y02P20/55 (EP)
Former IPC [2005/44]C07K7/06, A61K9/127, A61K47/42
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/44]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:KONJUGAT FÜR RETENTION IM BLUT UND KREBSGEWEBESPEZIFISCHE WIRKSTOFFFREISETZUNG[2005/44]
English:CONJUGATE FOR RETENTION IN BLOOD AND CANCER TISSUE-SPECIFIC DRUG DELIVERY[2005/44]
French:CONJUGUE DE RETENTION DANS LE SANG ET APPORT DE MEDICAMENT SPECIFIQUE DE TISSU CANCEREUX[2005/44]
Entry into regional phase10.08.2005Translation filed 
10.08.2005National basic fee paid 
10.08.2005Search fee paid 
10.08.2005Designation fee(s) paid 
10.08.2005Examination fee paid 
Examination procedure20.05.2004Request for preliminary examination filed
International Preliminary Examining Authority: JP
10.08.2005Examination requested  [2005/44]
17.07.2006Despatch of a communication from the examining division (Time limit: M04)
17.11.2006Reply to a communication from the examining division
18.01.2007Despatch of a communication from the examining division (Time limit: M04)
16.05.2007Reply to a communication from the examining division
25.04.2008Application refused, date of legal effect [2008/42]
25.04.2008Date of oral proceedings
26.05.2008Minutes of oral proceedings despatched
30.05.2008Despatch of communication that the application is refused, reason: substantive examination [2008/42]
Fees paidRenewal fee
23.01.2006Renewal fee patent year 03
25.01.2007Renewal fee patent year 04
23.01.2008Renewal fee patent year 05
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Documents cited:Search[A]WO9816202  (SEQUUS PHARM INC [US]) [A] * the whole document *;
 [A]  - KRATZ FELIX ET AL, "Development and in vitro efficacy of novel MMP2 and MMP9 specific doxorubicin albumin conjugates", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, (20010806), vol. 11, no. 15, ISSN 0960-894X, pages 2001 - 2006, XP002208108 [A] * the whole document *

DOI:   http://dx.doi.org/10.1016/S0960-894X(01)00354-7
International search[X]WO0100247  (LIPOSOME CO INC [US]);
 [X]WO9816240  (LIPOSOME CO INC [US]);
 [A]WO9105546  (LIPOSOME TECHNOLOGY INC [US]);
 [XP]  - BAE M. ET AL., "Metalloprotease-specific poly(ethylene gycol) methyl ether-peptide-doxorubicin conjugate for targeting anticancer drug delivery based on angiogenesis", DRUG EXP. CLIN. RES., (2003), vol. 29, no. 1, pages 15 - 23, XP009063289
 [A]  - MIYAZAKI KAORI ET AL., "Sosetsu matrix matalloproteinase no kozo to kino -tokuni gan no shinjun ten'i ni okeru yakuwari", SEIKAGAKU, (19961225), vol. 68, no. 12, pages 1791 - 1807, XP002980158
 [A]  - MEERS P., "Enzyme-activated targeting of liposomes", ADVANCED DRUG DELIVERY REVIEWS, (2001), vol. 53, pages 265 - 272, XP002980159

DOI:   http://dx.doi.org/10.1016/S0169-409X(01)00205-8
Examination   - Bremer et al. (2001) Nature Med. 7, 743-748.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.