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Extract from the Register of European Patents

EP About this file: EP1592801

EP1592801 - Method for identifying activated polymer complexes for secondary site-specific modification of protein target groups. [Right-click to bookmark this link]
Former [2005/45]TANDEM ANALYSES OF NONCOVALENTLY DRIVEN EFFECTORS FOR MODULATORY MAPPING OF ACTIVITIES OF PROTEIN SITES
[2009/51]
StatusNo opposition filed within time limit
Status updated on  11.03.2011
Database last updated on 15.06.2024
Most recent event   Tooltip04.10.2013Lapse of the patent in a contracting state
New state(s): HU		published on 06.11.2013  [2013/45]
Applicant(s)For all designated states
Advanced Proteome Therapeutics, Inc.
650 Albany Street, Nber 113
Boston, MA 02118 / US
[2010/31]
Former [2005/45]For all designated states
Advanced Proteome Therapeutics Inc.
2140 Taylor Street, 1206
San Francisco, CA 94133 / US
Inventor(s)01 / KRANTZ, Alexander
286 Commonwealth Avenue, Nr. 3
Boston, MA 02115 / US
 [2010/32]
Former [2010/28]01 / KRANTZ, Alexander
286 Commonwealth Avenue, Nr. 3
Boston, MA 02115 / US
Former [2010/16]01 / KRANTZ, Alexander
Advanced Proteome Therapeutics Inc. 650 Albany Street, 113
Boston, MA 02118 / US
Former [2005/45]01 / KRANTZ, Alexander
1200 Taylor Street, 14
San Francisco, CA 94108 / US
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastrasse 30
81925 München / DE
[N/P]
Former [2005/45]HOFFMANN EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date04702918.616.01.2004
[2005/45]
WO2004US01038
Priority number, dateUS20030440632P17.01.2003         Original published format: US 440632 P
[2005/45]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004066917
Date:12.08.2004
Language:EN
[2004/33]
Type: A2 Application without search report 
No.:EP1592801
Date:09.11.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 12.08.2004 takes the place of the publication of the European patent application.
[2005/45]
Type: B1 Patent specification 
No.:EP1592801
Date:05.05.2010
Language:EN
[2010/18]
Search report(s)International search report - published on:US11.08.2005
(Supplementary) European search report - dispatched on:EP01.04.2008
ClassificationIPC:C12Q1/00, G01N33/58, G01N33/68
[2008/17]
CPC:
G01N33/6845 (EP,US); C07K14/52 (EP,US); C07K16/00 (EP,US);
C12Q1/00 (EP,US); G01N33/58 (EP,US); G01N33/6842 (EP,US);
G01N2500/00 (EP,US) (-)
Former IPC [2005/45]C12Q1/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/45]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:Verfahren zur Identifizierung aktivierter Polymer-Komplexe zur sekundären Stellen-spezifischen Modifikation von Protein Ziel-Gruppen.[2009/51]
English:Method for identifying activated polymer complexes for secondary site-specific modification of protein target groups.[2009/51]
French:Procêdé pour identifier un complexe polymérique actif pour modifier des sites spécifiques secondaires d'un groupe cible de protéines.[2009/51]
Former [2005/45]TANDEMUNTERSUCHUNGEN NICHTKOVALENT ANGETRIEBENER EFFEKTOREN ZUR MODULATORISCHEN KARTIERUNG DER AKTIVITÄTEN VON PROTEINBINDUNGSSTELLEN
Former [2005/45]TANDEM ANALYSES OF NONCOVALENTLY DRIVEN EFFECTORS FOR MODULATORY MAPPING OF ACTIVITIES OF PROTEIN SITES
Former [2005/45]ANALYSES EN TANDEM D'EFFECTEURS ENTRAINES DE MANIERE NON COVALENTE POUR LA CARTOGRAPHIE MODULATRICE D'ACTIVITES DE SITES DE PROTEINE
Entry into regional phase17.08.2005National basic fee paid 
17.08.2005Search fee paid 
17.08.2005Designation fee(s) paid 
17.08.2005Examination fee paid 
Examination procedure17.08.2005Examination requested  [2005/45]
17.10.2005Amendment by applicant (claims and/or description)
04.07.2008Despatch of a communication from the examining division (Time limit: M08)
21.04.2009Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
29.06.2009Reply to a communication from the examining division
14.07.2009Despatch of a communication from the examining division (Time limit: M02)
10.09.2009Reply to a communication from the examining division
20.11.2009Communication of intention to grant the patent
10.03.2010Fee for grant paid
10.03.2010Fee for publishing/printing paid
Opposition(s)08.02.2011No opposition filed within time limit [2011/15]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
29.06.2009Request for further processing filed
29.06.2009Full payment received (date of receipt of payment)
Request granted
15.07.2009Decision despatched
Fees paidRenewal fee
27.01.2006Renewal fee patent year 03
29.01.2007Renewal fee patent year 04
25.01.2008Renewal fee patent year 05
30.01.2009Renewal fee patent year 06
25.01.2010Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT05.05.2010
BE05.05.2010
CY05.05.2010
CZ05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
HU05.05.2010
IT05.05.2010
NL05.05.2010
RO05.05.2010
SE05.05.2010
SI05.05.2010
SK05.05.2010
TR05.05.2010
BG05.08.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
IE16.01.2011
LU16.01.2011
MC31.01.2011
[2013/45]
Former [2013/44]AT05.05.2010
BE05.05.2010
CY05.05.2010
CZ05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
IT05.05.2010
NL05.05.2010
RO05.05.2010
SE05.05.2010
SI05.05.2010
SK05.05.2010
TR05.05.2010
BG05.08.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
IE16.01.2011
LU16.01.2011
MC31.01.2011
Former [2013/42]AT05.05.2010
BE05.05.2010
CY05.05.2010
CZ05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
IT05.05.2010
NL05.05.2010
RO05.05.2010
SE05.05.2010
SI05.05.2010
SK05.05.2010
BG05.08.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
IE16.01.2011
LU16.01.2011
MC31.01.2011
Former [2013/25]AT05.05.2010
BE05.05.2010
CY05.05.2010
CZ05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
IT05.05.2010
NL05.05.2010
RO05.05.2010
SE05.05.2010
SI05.05.2010
SK05.05.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
IE16.01.2011
LU16.01.2011
MC31.01.2011
Former [2012/08]AT05.05.2010
BE05.05.2010
CY05.05.2010
CZ05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
IT05.05.2010
NL05.05.2010
RO05.05.2010
SE05.05.2010
SI05.05.2010
SK05.05.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
IE16.01.2011
MC31.01.2011
Former [2011/42]AT05.05.2010
BE05.05.2010
CY05.05.2010
CZ05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
IT05.05.2010
NL05.05.2010
RO05.05.2010
SE05.05.2010
SI05.05.2010
SK05.05.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
MC31.01.2011
Former [2011/14]AT05.05.2010
BE05.05.2010
CY05.05.2010
CZ05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
IT05.05.2010
NL05.05.2010
RO05.05.2010
SE05.05.2010
SI05.05.2010
SK05.05.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
Former [2011/10]AT05.05.2010
CY05.05.2010
CZ05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
NL05.05.2010
RO05.05.2010
SE05.05.2010
SI05.05.2010
SK05.05.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
Former [2011/08]AT05.05.2010
CY05.05.2010
DK05.05.2010
EE05.05.2010
FI05.05.2010
NL05.05.2010
SE05.05.2010
SI05.05.2010
GR06.08.2010
ES16.08.2010
PT06.09.2010
Former [2011/07]AT05.05.2010
CY05.05.2010
DK05.05.2010
FI05.05.2010
NL05.05.2010
SE05.05.2010
SI05.05.2010
GR06.08.2010
ES16.08.2010
Former [2011/05]AT05.05.2010
CY05.05.2010
FI05.05.2010
NL05.05.2010
SE05.05.2010
SI05.05.2010
GR06.08.2010
ES16.08.2010
Former [2011/01]AT05.05.2010
FI05.05.2010
NL05.05.2010
SE05.05.2010
SI05.05.2010
GR06.08.2010
ES16.08.2010
Former [2010/52]AT05.05.2010
FI05.05.2010
NL05.05.2010
SE05.05.2010
SI05.05.2010
ES16.08.2010
Former [2010/50]AT05.05.2010
FI05.05.2010
NL05.05.2010
SE05.05.2010
ES16.08.2010
Former [2010/46]NL05.05.2010
ES16.08.2010
Former [2010/45]NL05.05.2010
Documents cited:Search[X]US2002064799  (CRAVATT BENJAMIN F [US], et al) [X] 1-16,22 * the whole document * * paragraphs [0097] , [0099] * * claims 1-13 *;
 [X]WO02063271  (ACTIVX BIOSCIENCES INC [US], et al) [X] 1-16,22 * the whole document * * claims 1-36 * * paragraphs [0035] , [0048] , [0059] *;
 [X]  - POWDERS S P ET AL, "USE OF PHOTOAFFINITY PROBES CONTAINING POLYETHYLENE GLYCOL SPACERS FOR TOPOGRAPHICAL MAPPING OF THE CHOLECYSTOKININ RECEPTOR COMPLEX", BIOCHEMISTRY, (1991), vol. 30, no. 3, ISSN 0006-2960, pages 676 - 682, XP002443891 [X] 1-16,22 * the whole document * * Scheme 1 *

DOI:   http://dx.doi.org/10.1021/bi00217a013
 [X]  - LEELASVATANAKIJ L ET AL, "A SOLID-PHASE SYNTHETIC STRATEGY FOR THE PREPARATION OF PEPTIDE-BASED AFFINITY LABELS: SYNTHESISOF DYNORPHIN A ANALOGS", JOURNAL OF PEPTIDE RESEARCH, BLACKWELL PUBLISHING LTD., OXFORD, GB, (200008), vol. 56, no. 2, ISSN 1397-002X, pages 80 - 87, XP000958209 [X] 1-16,22 * the whole document * * figure 1 *

DOI:   http://dx.doi.org/10.1034/j.1399-3011.2000.00736.x
 [X]  - EVANS B ET AL, "INACTIVATION OF CATHEPSIN B BY ACTIVE SITE DIRECTED DI SULFIDE EXCHANGE APPLICATION IN COVALENT AFFINITY CHROMATOGRAPHY", JOURNAL OF BIOLOGICAL CHEMISTRY, (1983), vol. 258, no. 17, ISSN 0021-9258, pages 10227 - 10232, XP002443892 [X] 1-16,22 * the whole document * * abstract * * figure 3 *
 [X]  - BING D H ET AL, "M-O-2 CHLORO-5-FLUOROSULFONYLPHENYLUREIDOPHENOXYBUTOXY BENZAMIDINE AFFINITY LABELING REAGENT WHICH CAN IDENTIFY SECONDARY BINDING SITES OF COAGULATION COMPLEMENT AND FIBRINOLYTIC SERINE PROTEASES", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1979), Database accession no. PREV198018031914, XP002443894 [X] 1-16,22 * abstract *
 [X]  - SMITH G B ET AL, "Functional domains of GABAA receptors", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER, HAYWARTH, GB, (199505), vol. 16, no. 5, ISSN 0165-6147, pages 162 - 168, XP004207485 [X] 1-16,22 * the whole document * * page 164 *

DOI:   http://dx.doi.org/10.1016/S0165-6147(00)89009-4
 [A]  - RUPPERT J ET AL, "AUTOMATIC IDENTIFICATION AND REPRESENTATION OF PROTEIN BINDING SITES FOR MOLECULAR DOCKING", PROTEIN SCIENCE, CAMBRIDGE UNIVERSITY PRESS, CAMBRIDGE, GB, (1997), vol. 6, no. 3, ISSN 0961-8368, pages 524 - 533, XP009027990 [A] 1-16,22 * the whole document *
    [ ] - THROMBOSIS AND HAEMOSTASIS, 7TH INTERNATIONAL CONGRESS ON THROMBOSIS AND HAEMOSTASIS, LONDON, ENGLAND, JULY 15-20, 1979. THROMB, (1979), vol. 42, no. 1, ISSN 0340-6245, page 96
International search[A]US6335155  (WELLS JIM [US], et al)
Examination   - MATTOS ET AL., "Analogous inhibitors of elastase do not always bind analogously.", STRUCTURAL BIOLOGY, (1994), vol. 1, no. 1, pages 55 - 58
    - LIANG ET AL., "Anatomy of protein pockets and cavities: Measurement of binding site geometry and implications for ligand design.", PROTEIN SCIENCE, vol. 7, pages 1884 - 1897
by applicantUS6238667
    - B. EVANS; E. SHAW, THE JOURNAL OF BIOLOGICAL CHEMISTRY, (1983), vol. 258, pages 10227 - 10232
    - RUPPERT ET AL., PROTEIN SCI., (1997), vol. 6, pages 524 - 533
    - DAVIS ET AL., BIOCHEMISTRY, (1996), vol. 20, pages 2482 - 2488
    - SALTO ET AL., J. BIOI. CHEM., (1994), vol. 269, pages 10691 - 10698
    - HOUGHTEN, R., A. ANNU. REV. PHARMACOL. TOXICOL., (2000), vol. 40, pages 273 - 282
    - SCHRAMM ET AL., BIOCHEM. BIOPHYS. RES. COMMUN., (1993), vol. 194, pages 593 - 600
    - DANIELSON ET AL., ADV. EXP. MED. BIOL., (1998), vol. 463, pages 99 - 103
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.