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Extract from the Register of European Patents

EP About this file: EP1587547

EP1587547 - AMYLOID-BINDING, METAL-CHELATING AGENTS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  17.10.2008
Database last updated on 27.07.2024
Most recent event   Tooltip17.10.2008Application deemed to be withdrawnpublished on 19.11.2008  [2008/47]
Applicant(s)For all designated states
THE GENERAL HOSPITAL CORPORATION
55 Fruit Street
Boston, MA 02114 / US
[2005/43]
Inventor(s)01 / HUANG, Xudong
11 Patricia Circle
Andover, MA 01810 / US
 [2005/52]
Former [2005/43]01 / HUANG, Xudong
Boston, MA / US
Representative(s)Gambell, Derek
Graham Watt & Co LLP
St Botolph's House
7-9 St Botolph's Road
Sevenoaks
Kent TN13 3AJ / GB
[N/P]
Former [2005/43]Gambell, Derek
Graham Watt & Co LLP St Botolph's House 7-9 St Botolph's Road Sevenoaks
Kent TN13 3AJ / GB
Application number, filing date04704402.922.01.2004
[2005/43]
WO2004US01669
Priority number, dateUS20030441719P22.01.2003         Original published format: US 441719 P
[2005/43]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004064869
Date:05.08.2004
Language:EN
[2004/32]
Type: A2 Application without search report 
No.:EP1587547
Date:26.10.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 05.08.2004 takes the place of the publication of the European patent application.
[2005/43]
Search report(s)International search report - published on:EP24.03.2005
ClassificationIPC:A61K49/10, A61K51/04, A61K31/425, A61P25/28
[2005/43]
CPC:
A61K31/425 (EP,US); A61K49/0002 (EP,US); A61K49/0004 (EP,US);
A61K49/085 (EP,US); A61K49/10 (EP,US); A61K49/103 (EP,US);
A61K51/0478 (EP,US); A61P19/02 (EP); A61P25/00 (EP);
A61P25/28 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P35/00 (EP); C07D277/66 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2005/43]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:AMYLOID-BINDUNG, METALLCHELAT-BILDNER[2005/43]
English:AMYLOID-BINDING, METAL-CHELATING AGENTS[2005/43]
French:AGENT DE CHELATION METALLIQUE, A LIAISON AMYLOIDE[2005/43]
Entry into regional phase05.08.2005National basic fee paid 
21.09.2005Designation fee(s) paid 
21.09.2005Examination fee paid 
Examination procedure16.08.2004Request for preliminary examination filed
International Preliminary Examining Authority: EP
03.08.2005Amendment by applicant (claims and/or description)
21.09.2005Examination requested  [2005/46]
24.02.2006Despatch of a communication from the examining division (Time limit: M06)
01.09.2006Reply to a communication from the examining division
16.01.2008Despatch of a communication from the examining division (Time limit: M04)
29.05.2008Application deemed to be withdrawn, date of legal effect  [2008/47]
02.07.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2008/47]
Fees paidRenewal fee
24.01.2006Renewal fee patent year 03
29.01.2007Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.01.200805   M06   Not yet paid
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[X]WO02085903  (KUNG HANK [US], et al) [X] 1,6,7,34,46,47,51,56,57,59,60,65,66 * claims 8,17,23,24 * * page 7, paragraph 20 * * page 30, paragraph 78 * * page 32, paragraph 86 * * page 33, paragraph 90 *;
 [X]WO9741856  (MASSACHUSETTS INST TECHNOLOGY [US], et al) [X] 16-18,20,22,27-29,40,41,43,67-84,90-95 * claims 1,24 *;
 [X]WO0228441  (CALIFORNIA INST OF TECHN [US]) [X] 16-18,20-22,24-26,40,41,67-87,90-95 * claims 1,6,8,11,12 * * page 7, line 16 - line 26 *;
 [A]EP0681844  (KANEGAFUCHI CHEMICAL IND [JP]) [A] * claims *
 [A]  - KLUNK W E ET AL, "Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain", LIFE SCIENCES, PERGAMON PRESS, OXFORD, GB, (20010817), vol. 69, no. 13, ISSN 0024-3205, pages 1471 - 1484, XP002189042 [A] * abstract *

DOI:   http://dx.doi.org/10.1016/S0024-3205(01)01232-2
 [A]  - DEZUTTER N A ET AL, "99mTc-MAMA-chrysamine G, a probe for beta-amyloid protein of Alzheimer's disease", EUROPEAN JOURNAL OF NUCLEAR MEDICINE, BERLIN, DE, (199911), vol. 26, no. 11, ISSN 0340-6997, pages 1392 - 1399, XP002193810 [A] * abstract * * page 1393, column L, paragraph 4 *

DOI:   http://dx.doi.org/10.1007/s002590050470
 [A]  - WANG YANMING ET AL, "Synthesis and evaluation of 2-(3'-iodo-4'-aminophenyl)-6-hydroxybenzo thiazole for in vivo quantitation of amyloid deposits in Alzheimer's disease", JOURNAL OF MOLECULAR NEUROSCIENCE, (200208), vol. 19, no. 1-2, ISSN 0895-8696, pages 11 - 16, XP008031471 [A] * page 15, column L, paragraph 1 * * page 15, column R, paragraph 2 *
 [A]  - WANG YANMING ET AL, "Synthesis and 11C-labelling of (E,E)-1-(3',4'-dihydroxystyryl)-4-(3'- methoxy-4'-hydroxystyryl) benzene for PET imaging of amyloid deposits", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, (200207), vol. 45, no. 8, ISSN 0362-4803, pages 647 - 664, XP002284024 [A] * page 653, paragraph 2 * * figure 1 *

DOI:   http://dx.doi.org/10.1002/jlcr.585
 [A]  - BACSKAI BRIAN J ET AL, "Imaging amyloid-beta deposits in vivo", JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, (200209), vol. 22, no. 9, ISSN 0271-678X, pages 1035 - 1041, XP008031462 [A] * page 1038, column L, paragraph 2 *

DOI:   http://dx.doi.org/10.1097/00004647-200209000-00001
 [X]  - ZHEN WEIGUO ET AL, "Synthesis and amyloid binding properties of rhenium complexes: Preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain", JOURNAL OF MEDICINAL CHEMISTRY, (19990729), vol. 42, no. 15, ISSN 0022-2623, pages 2805 - 2815, XP002310402 [X] 16-18,20,27-29,40,41,43,67-84,90-95 * page 2805, abstract *

DOI:   http://dx.doi.org/10.1021/jm990103w
 [X]  - PODUSLO JOSEPH F ET AL, "Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging.", NEUROBIOLOGY OF DISEASE, (200211), vol. 11, no. 2, ISSN 0969-9961, pages 315 - 329, XP002310403 [X] 16-18,20,22,24-26,40,41,67-87,90-95 * page 315, abstract *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.