| EP1599220 - SELECTION OF PATIENTS WITH INCREASED RESPONSIVENESS TO BOTULINUM TOXIN [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 23.05.2014 Database last updated on 21.03.2026 | Most recent event Tooltip | 15.07.2016 | Lapse of the patent in a contracting state New state(s): TR | published on 17.08.2016 [2016/33] | Applicant(s) | For all designated states Botulinum Toxin Research Associates, Inc. 1261 Furnace Brook Parkway Quincy Massachusetts 02109 / US | [2013/29] |
| Former [2005/48] | For all designated states Botulinum Toxin Research Associates, Inc. 1261 Furnace Brook Parkway Quincy Massachusetts 02109 / US | Inventor(s) | 01 /
BORODIC, Gary, E. 90 Kennington Road Canton, MA 02021 / US | [2005/48] | Representative(s) | Kador & Partner Part mbB Corneliusstraße 15 80469 München / DE | [N/P] |
| Former [2013/29] | Kador & Partner Corneliusstrasse 15 80469 München / DE | ||
| Former [2005/48] | Kador & Partner Corneliusstrasse 15 80469 München / DE | Application number, filing date | 04718358.7 | 08.03.2004 | [2005/48] | WO2004IB00630 | Priority number, date | US20030453040P | 06.03.2003 Original published format: US 453040 P | [2005/48] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2004078200 | Date: | 16.09.2004 | Language: | EN | [2004/38] | Type: | A1 Application with search report | No.: | EP1599220 | Date: | 30.11.2005 | Language: | EN | The application published by WIPO in one of the EPO official languages on 16.09.2004 takes the place of the publication of the European patent application. | [2005/48] | Type: | B1 Patent specification | No.: | EP1599220 | Date: | 17.07.2013 | Language: | EN | [2013/29] | Search report(s) | International search report - published on: | EP | 16.09.2004 | Classification | IPC: | A61K38/48, A61P25/00 | [2005/48] | CPC: |
A61K38/4893 (EP,US);
A61P25/00 (EP)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2005/48] | Title | German: | AUSWAHL VON PATIENTEN MIT ERHÖHTEM ANSPRECHEN AUF BOTULINUSTOXIN | [2005/48] | English: | SELECTION OF PATIENTS WITH INCREASED RESPONSIVENESS TO BOTULINUM TOXIN | [2005/48] | French: | SELECTION DE PATIENTS A SENSIBILITE ACCRUE A LA TOXINE BOTULIQUE | [2005/48] | Entry into regional phase | 24.08.2005 | National basic fee paid | 24.08.2005 | Designation fee(s) paid | 24.08.2005 | Examination fee paid | Examination procedure | 24.08.2005 | Examination requested [2005/48] | 09.05.2007 | Despatch of a communication from the examining division (Time limit: M03) | 07.08.2007 | Reply to a communication from the examining division | 11.11.2008 | Despatch of a communication from the examining division (Time limit: M03) | 11.02.2009 | Reply to a communication from the examining division | 18.02.2011 | Cancellation of oral proceeding that was planned for 04.03.2011 | 04.03.2011 | Date of oral proceedings (cancelled) | 07.03.2011 | Despatch of a communication from the examining division (Time limit: M04) | 08.07.2011 | Reply to a communication from the examining division | 22.02.2013 | Communication of intention to grant the patent | 03.06.2013 | Fee for grant paid | 03.06.2013 | Fee for publishing/printing paid | Divisional application(s) | EP07020648.7 / EP1905448 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 09.05.2007 | Opposition(s) | 22.04.2014 | No opposition filed within time limit [2014/26] | Fees paid | Renewal fee | 24.08.2005 | Renewal fee patent year 03 | 28.03.2007 | Renewal fee patent year 04 | 31.03.2008 | Renewal fee patent year 05 | 30.03.2009 | Renewal fee patent year 06 | 24.02.2010 | Renewal fee patent year 07 | 25.03.2011 | Renewal fee patent year 08 | 28.03.2012 | Renewal fee patent year 09 | 27.03.2013 | Renewal fee patent year 10 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 08.03.2004 | AT | 17.07.2013 | BE | 17.07.2013 | BG | 17.07.2013 | CY | 17.07.2013 | CZ | 17.07.2013 | DK | 17.07.2013 | EE | 17.07.2013 | FI | 17.07.2013 | IT | 17.07.2013 | MC | 17.07.2013 | NL | 17.07.2013 | PL | 17.07.2013 | RO | 17.07.2013 | SE | 17.07.2013 | SI | 17.07.2013 | SK | 17.07.2013 | TR | 17.07.2013 | GR | 18.10.2013 | ES | 28.10.2013 | PT | 18.11.2013 | IE | 08.03.2014 | LU | 08.03.2014 | CH | 31.03.2014 | LI | 31.03.2014 | [2016/33] |
| Former [2016/32] | HU | 08.03.2004 | |
| AT | 17.07.2013 | ||
| BE | 17.07.2013 | ||
| BG | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| CZ | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| EE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| IT | 17.07.2013 | ||
| MC | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| SK | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| IE | 08.03.2014 | ||
| LU | 08.03.2014 | ||
| CH | 31.03.2014 | ||
| LI | 31.03.2014 | ||
| Former [2016/27] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| BG | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| CZ | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| EE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| IT | 17.07.2013 | ||
| MC | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| SK | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| IE | 08.03.2014 | ||
| LU | 08.03.2014 | ||
| CH | 31.03.2014 | ||
| LI | 31.03.2014 | ||
| Former [2016/25] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| BG | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| CZ | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| EE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| IT | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| SK | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| IE | 08.03.2014 | ||
| LU | 08.03.2014 | ||
| CH | 31.03.2014 | ||
| LI | 31.03.2014 | ||
| Former [2015/08] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| CZ | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| EE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| IT | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| SK | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| IE | 08.03.2014 | ||
| LU | 08.03.2014 | ||
| CH | 31.03.2014 | ||
| LI | 31.03.2014 | ||
| Former [2015/07] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| CZ | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| EE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| IT | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| SK | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| IE | 08.03.2014 | ||
| LU | 08.03.2014 | ||
| Former [2014/48] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| CZ | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| EE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| IT | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| SK | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| LU | 08.03.2014 | ||
| Former [2014/24] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| CZ | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| EE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| IT | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| SK | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/23] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| CZ | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| EE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| SK | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/22] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| RO | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/21] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| DK | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/18] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| CY | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/14] | CY | 19.06.2013 | |
| AT | 17.07.2013 | ||
| BE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| NL | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/12] | CY | 19.06.2013 | |
| AT | 17.07.2013 | ||
| BE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| SI | 17.07.2013 | ||
| GR | 18.10.2013 | ||
| ES | 28.10.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/11] | CY | 19.06.2013 | |
| AT | 17.07.2013 | ||
| BE | 17.07.2013 | ||
| FI | 17.07.2013 | ||
| PL | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/10] | CY | 19.06.2013 | |
| AT | 17.07.2013 | ||
| BE | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/09] | AT | 17.07.2013 | |
| BE | 17.07.2013 | ||
| SE | 17.07.2013 | ||
| PT | 18.11.2013 | ||
| Former [2014/08] | PT | 18.11.2013 | Cited in | International search | [A] BORODIC G E ET AL: "BOTULINUM TOXIN HERAPY FOR PAIN AN DINLAMMATORY DISORDERS: MECHANISMS AND THERAPEUTIC EFFECTS", EXPERT OPINION ON INVESTIGATIONAL DRUGS, ASHLEY PUBLICATIONS LTD., LONDON, GB, vol. 8, no. 10, August 2001 (2001-08-01), pages 1531 - 1544, XP008005178, ISSN: 1354-3784 [A] 1-26 * page 1535 * * page 1540 * DOI: http://dx.doi.org/10.1517/13543784.10.8.1531 | [A] DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 25 November 1997 (1997-11-25), GILADI NIR: "The mechanism of action of Botulinum toxin type A in focal dystonia is most probably through its dual effect on efferent (motor) and afferent pathways at the injected site", XP002286557, Database accession no. PREV199800052677 [A] 25,26 * abstract * | [A] JOURNAL OF THE NEUROLOGICAL SCIENCES, vol. 152, no. 2, 25 November 1997 (1997-11-25), pages 132 - 135, ISSN: 0022-510X |