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Extract from the Register of European Patents

EP About this file: EP1619193

EP1619193 - SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  29.04.2011
Database last updated on 14.09.2024
Most recent event   Tooltip29.04.2011Application deemed to be withdrawnpublished on 01.06.2011  [2011/22]
Applicant(s)For all designated states
ONO PHARMACEUTICAL CO., LTD.
1-5, Doshomachi 2-chome Chuo-ku
Osaka-shi, Osaka 541-8526 / JP
[N/P]
Former [2006/04]For all designated states
ONO PHARMACEUTICAL CO., LTD.
1-5, Doshomachi 2-chome, Chuo-ku Osaka-shi
Osaka 541-8526 / JP
Inventor(s)01 / NISHIZAWA, Rena, c/o Ono Pharmaceutical Co., Ltd.
1-1, Sakurai 3-chome, Shimamoto-cho
Mishima-gun, Osaka 618-8585 / JP
02 / TAKAOKA, Yoshikazu c/o Ono Pharmaceutical Co., Ltd
1-1, Sakurai 3-chome, Shimamoto-cho
Mishima-gun, Osaka 618-8585 / JP
03 / HABASHITA, Hiromu c/o Ono Pharmaceutical Co., Ltd.
1-1, Sakurai 3-chome, Shimamoto-cho
Mishima-gun, Osaka 618-8585 / JP
04 / SHIBAYAMA, Shiro c/o Ono Pharmaceutical Co., Ltd.
17-2, Wadai
Tsukuba-shi, Ibaraki 300-4247 / JP
05 / KOKUBO, Masaya, c/o Ono Pharmaceutical Co., Ltd.
1-1, Sakurai 3-chome, Shimamoto-cho
Mishima-gun, Osaka 618-8585 / JP
 [2006/04]
Representative(s)McCluskie, Gail Wilson, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2009/44]McCluskie, Gail Wilson, et al
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Former [2006/04]Henkel, Feiler & Hänzel
Patentanwälte Maximiliansplatz 21
80333 München / DE
Application number, filing date04727985.616.04.2004
[2006/04]
WO2004JP05493
Priority number, dateJP2003011418818.04.2003         Original published format: JP 2003114188
[2006/04]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004092169
Date:28.10.2004
Language:JA
[2004/44]
Type: A1 Application with search report 
No.:EP1619193
Date:25.01.2006
Language:EN
[2006/04]
Search report(s)International search report - published on:JP28.10.2004
(Supplementary) European search report - dispatched on:EP09.07.2010
ClassificationIPC:C07D471/10, A61K31/438, A61K31/527, A61K31/5513, A61K45/06, A61P1/04, A61P1/16, A61P3/10, A61P9/10, A61P11/00, A61P11/02, A61P11/06, A61P13/12, A61P17/00, A61P17/04, A61P17/06, A61P19/02, A61P25/00, A61P27/02, A61P29/00, A61P31/18
[2006/15]
CPC:
C07D471/10 (EP,US); A61K31/438 (EP,US); A61P1/00 (EP);
A61P1/04 (EP); A61P1/16 (EP); A61P11/00 (EP);
A61P11/02 (EP); A61P11/06 (EP); A61P11/16 (EP);
A61P13/12 (EP); A61P17/00 (EP); A61P17/04 (EP);
A61P17/06 (EP); A61P17/08 (EP); A61P19/02 (EP);
A61P25/00 (EP); A61P27/02 (EP); A61P27/16 (EP);
A61P29/00 (EP); A61P3/10 (EP); A61P31/18 (EP);
A61P35/00 (EP); A61P35/04 (EP); A61P37/02 (EP);
A61P37/06 (EP); A61P37/08 (EP); A61P43/00 (EP);
A61P9/08 (EP); A61P9/10 (EP) (-)
Former IPC [2006/04]C07D471/10
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/04]
Extension statesALNot yet paid
HRNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:SPIROPIPERIDINVERBINDUNG UND DEREN MEDIZINISCHE VERWENDUNG[2006/04]
English:SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF[2006/04]
French:COMPOSE DE SPIROPIPERIDINE ET SON UTILISATION MEDICINALE[2006/04]
Entry into regional phase07.11.2005Translation filed 
07.11.2005National basic fee paid 
07.11.2005Search fee paid 
07.11.2005Designation fee(s) paid 
07.11.2005Examination fee paid 
Examination procedure07.11.2005Amendment by applicant (claims and/or description)
07.11.2005Examination requested  [2006/04]
07.10.2010Application deemed to be withdrawn, date of legal effect  [2011/22]
14.12.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2011/22]
Divisional application(s)EP10013312.3  / EP2364982
Fees paidRenewal fee
27.04.2006Renewal fee patent year 03
27.04.2007Renewal fee patent year 04
31.03.2008Renewal fee patent year 05
30.04.2009Renewal fee patent year 06
25.03.2010Renewal fee patent year 07
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XY]US5962462  (MILLS SANDER G [US], et al) [X] 1-3,6,7,10-19 * see all examples and their chemokine receptor antagonistic activity and especially examples 17, 169 and 170 * [Y] 1-6,10-19;
 [X]US6291469  (FISHER MATTHEW J [US], et al) [X] 1-6 * see steps A of examples 20 and 21, steps B of examples 5, 26, 30 and 32 and step C of example 13 *;
 [XY]JP2002348288  (ONO PHARMACEUTICAL CO) [X] 1-6,10-19 * see the compounds of formula (I) wherein R1 is hydrogen and the rings AB are of formulas (c), (d), (e) on p. 13, (o) and (r) on p. 14, (u) on p. 15, and (ccc) on p. 17 which are equivalent to formulas (a) aqnd (bbb) and their chemokine receptor anatgonistic activity * [Y] 1-6,10-19;
 [X]WO03024941  (JAPAN TOBACCO INC [JP], et al) [X] 1-6,10-19 * see compounds 1-28, 1-29 on p. 69, 5-3 on p. 99 and especially 6-2 on p. 103 and their anti HIV activity *;
 [X]JP2003104884  (BANYU PHARMA CO LTD) [X] 1-3 * see the starting materials of formula III of the corresponding examples *;
 [XP]EP1308439  (WELFIDE CORP [JP]) [XP] 1-3 * see the spiro-piperidine starting materials of examples 129 and 130 *;
 [YP]EP1378510  (ONO PHARMACEUTICAL CO [JP]) [YP] 1-6,10-19 * see compounds of formula I and chemokine antagonistic activity *;
 [X]  - PAUL W SMITH ET AL, "New Spiropiperidines as Potent and Selective Non-Peptide Tachykinin NK2 Receptor Antagonists", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, (19950101), vol. 38, no. 19, ISSN 0022-2623, pages 3772 - 3779, XP009135475 [X] 1-6 * see deprotection (step c) of compound 13 in scheme 2, of compound 18 in scheme 3 (step e) and of compound 19 in scheme 4 (step b) *

DOI:   http://dx.doi.org/10.1021/jm00019a006
International search[X]WO03020721  (NOVARTIS AG [CH], et al);
 [X]WO0206234  (TAKEDA CHEMICAL INDUSTRIES LTD [JP], et al);
 [X]JPH11512723  ;
 [X]JPS4972332  ;
 [X]JPS4913184  ;
 [X]JPH0418092  (YAMANOUCHI PHARMA CO LTD);
 [X]JP2003104884  (BANYU PHARMA CO LTD);
 [X]JPH08512034  ;
 [X]JP2002348288  (ONO PHARMACEUTICAL CO);
 [XP]WO03057698  (ACADIA PHARM INC [US]);
 [A]WO02074770  (ONO PHARMACEUTICAL CO [JP], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.