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Extract from the Register of European Patents

EP About this file: EP1633409

EP1633409 - IMPROVED CALCIUM PHOSPHATE BONE CEMENTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.10.2012
Database last updated on 03.10.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Ortus Medical Limited;
74 Bath Green Longwell Green
Bristol, BS30 9DG / GB
[2006/11]
Inventor(s)01 / BARRALET, Jake
304 Franklin Road
Birmingham B30 1NE / GB
02 / GBURECK, Uwe
Schiestlstrasse 2
97080 Wurzburg / DE
03 / THULL, Roger
Wald kugelweg 23
97080 Wurzburg / DE
 [2006/11]
Representative(s)Gaunt, Thomas Derrick, et al
Ablett & Stebbing
7-8 Market Place
London W1W 8AG / GB
[N/P]
Former [2010/31]Gaunt, Thomas Derrick, et al
Ablett & Stebbing 101/103 Baker Street London
W1U 6FQ / GB
Former [2006/11]Ward, David Ian
Marks & Clerk, Alpha Tower, Suffolk Street, Queensway
Birmingham B1 1TT / GB
Application number, filing date04733845.419.05.2004
[2006/11]
WO2004GB02179
Priority number, dateGB2003001184623.05.2003         Original published format: GB 0311846
[2006/11]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004103419
Date:02.12.2004
Language:EN
[2004/49]
Type: A1 Application with search report 
No.:EP1633409
Date:15.03.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 02.12.2004 takes the place of the publication of the European patent application.
[2006/11]
Type: B1 Patent specification 
No.:EP1633409
Date:30.11.2011
Language:EN
[2011/48]
Search report(s)International search report - published on:EP02.12.2004
ClassificationIPC:A61L24/00
[2006/11]
CPC:
A61L24/0063 (EP,US); A61L27/425 (EP,US); A61L2430/02 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/11]
TitleGerman:VERBESSERTE CALCIUM PHOSPHAT KNOCHENZEMENTE[2006/11]
English:IMPROVED CALCIUM PHOSPHATE BONE CEMENTS[2006/11]
French:CIMENTS DE PHOSPHATE DE CALCIUM AMELIORES POUR LES OS[2006/11]
Entry into regional phase31.10.2005National basic fee paid 
31.10.2005Designation fee(s) paid 
31.10.2005Examination fee paid 
Examination procedure31.10.2005Examination requested  [2006/11]
09.08.2007Despatch of a communication from the examining division (Time limit: M06)
27.03.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
03.06.2008Reply to a communication from the examining division
10.12.2009Despatch of a communication from the examining division (Time limit: M06)
21.06.2010Reply to a communication from the examining division
25.05.2011Cancellation of oral proceeding that was planned for 31.05.2011
31.05.2011Date of oral proceedings (cancelled)
08.06.2011Communication of intention to grant the patent
17.10.2011Fee for grant paid
17.10.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  09.08.2007
Opposition(s)31.08.2012No opposition filed within time limit [2012/45]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
05.06.2008Request for further processing filed
05.06.2008Full payment received (date of receipt of payment)
Fees paidRenewal fee
23.03.2006Renewal fee patent year 03
14.05.2007Renewal fee patent year 04
28.03.2008Renewal fee patent year 05
29.05.2009Renewal fee patent year 06
24.11.2010Renewal fee patent year 07
31.05.2011Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.05.201007   M06   Fee paid on   24.11.2010
Opt-out from the exclusive  Tooltip
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.05.2004
AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
FI30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
TR30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
PT30.03.2012
GB19.05.2012
IE19.05.2012
LU19.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
[2014/34]
Former [2014/27]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
FI30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
TR30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
PT30.03.2012
GB19.05.2012
IE19.05.2012
LU19.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2014/21]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
FI30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
TR30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
PT30.03.2012
GB19.05.2012
IE19.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/29]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
FI30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
PT30.03.2012
GB19.05.2012
IE19.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/23]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
PT30.03.2012
GB19.05.2012
IE19.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/22]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
PT30.03.2012
GB19.05.2012
IE19.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/21]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
PT30.03.2012
GB19.05.2012
IE19.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/20]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
PT30.03.2012
IE19.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/07]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
PT30.03.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/03]BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
PT30.03.2012
MC31.05.2012
Former [2012/37]BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
IT30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
PT30.03.2012
Former [2012/36]BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
NL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
PT30.03.2012
Former [2012/35]BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
BG29.02.2012
GR01.03.2012
PT30.03.2012
Former [2012/34]BE30.11.2011
CY30.11.2011
CZ30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
GR01.03.2012
PT30.03.2012
Former [2012/28]BE30.11.2011
CY30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
GR01.03.2012
PT30.03.2012
Former [2012/25]BE30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
GR01.03.2012
PT30.03.2012
Former [2012/24]NL30.11.2011
SE30.11.2011
SI30.11.2011
GR01.03.2012
PT30.03.2012
Former [2012/23]NL30.11.2011
GR01.03.2012
PT30.03.2012
Cited inInternational search[X]US6425949  (LEMAITRE JACQUES [CH], et al) [X] 1-5,8,10-25,27-30 * column 3, line 27 - line 42 * * example 1 * * claim 8 *;
 [X]  - GBURECK U ET AL, "Surface properties of calcium phosphate particles for self setting bone cements", BIOMOLECULAR ENGINEERING, ELSEVIER, NEW YORK, NY, US, (200208), vol. 19, no. 2-6, ISSN 1389-0344, pages 51 - 55, XP004378070 [X] 1,2,10-20,29,30 * the whole document * * page 51, column R *

DOI:   http://dx.doi.org/10.1016/S1389-0344(02)00010-2
 [X]  - BOHNER M ET AL, "EFFECTS OF SULFATE, PYROPHOSPHATE, AND CITRATE IONS ON THE PHYSICOCHEMICAL PROPERTIES OF CEMENTS MADE OF BETA-TRICALCIUM PHOSPHATE-PHOSPHORIC ACID-WATER MIXTURES", JOURNAL OF THE AMERICAN CERAMIC SOCIETY, AMERICAN CERAMIC SOCIETY. COLUMBUS, US, (19960601), vol. 79, no. 6, ISSN 0002-7820, pages 1427 - 1434, XP000596067 [X] 21-25,27,28 * figure 9 *

DOI:   http://dx.doi.org/10.1111/j.1151-2916.1996.tb08746.x
 [X]  - OTSUKA M ET AL, "PARTICLE SIZE EFFECT OF METASTABLE CALCIUM PHOSPHATES ON CRUSHING STRENGTH OF SELF-SETTING BIOACTIVE CALCIUM PHOSPHATE CEMENT", CHEMICAL AND PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOCIETY OF JAPAN. TOKYO, JP, (19931101), vol. 41, no. 11, ISSN 0009-2363, pages 2055 - 2057, XP009001135 [X] 29 * figure 5; table II *

DOI:   http://dx.doi.org/10.1002/jbm.820290105
 [PX]  - GBURECK U ET AL, "Ionic modification of calcium phosphate cement viscosity. Part I: hypodermic injection and strength improvement of apatite cement", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, (20031106), vol. 25, no. 11, ISSN 0142-9612, pages 2187 - 2195, XP004485137 [PX] 1-30 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.biomaterials.2003.08.066
 [PX]  - BARRALET J E ET AL, "Ionic modification of calcium phosphate cement viscosity. Part II: hypodermic injection and strength improvement of brushite cement", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, (20031119), vol. 25, no. 11, ISSN 0142-9612, pages 2197 - 2203, XP004485138 [PX] 1-30 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.biomaterials.2003.09.085
 [DA]  - FERNANDEZ ENRIQUE ET AL, "Kinetic study of citric acid influence on calcium phosphate bone cements as water-reducing agent", J. BIOMED. MATER. RES.; JOURNAL OF BIOMEDICAL MATERIALS RESEARCH SEP 15 2002, (20020915), vol. 61, no. 4, pages 653 - 659, XP002301639 [DA] 1-30 * abstract * * figures 1,2 * * page 657, column R, paragraph 2 - paragraph 3 *

DOI:   http://dx.doi.org/10.1002/jbm.10264
 [A]  - CHEN D, "[Physical properties of apatite bone cement]", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (200003), Database accession no. NLM10879182, XP002301640 [A] 1-30 * abstract *
    [ ] - SHENG WU YI XUE GONG CHENG XUE ZA ZHI = JOURNAL OF BIOMEDICAL ENGINEERING = SHENGWU YIXUE GONGCHENGXUE ZAZHI. MAR 2000, (200003), vol. 17, no. 1, ISSN 1001-5515, pages 13 - 15 , 18
 [T]  - CHEN D-M ET AL, "Study on the mechanical properties of hydroxyapatite bone cement", EMBASE, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (2004), Database accession no. EMB-2004217475, XP002301641 [T] 1-30 * abstract *
    [ ] - CHINESE JOURNAL OF CLINICAL REHABILITATION 2004 CHINA, (2004), vol. 8, no. 8, ISSN 1671-5926, pages 1589 - 1591
by applicant   - LEROUX L, "Effects of various adjuvants (lactic acid, glycerol and chitosan) on the injectability of a calcium phosphate cement", BONE, (1999), vol. 25, no. 2, doi:doi:10.1016/S8756-3282(99)00130-1, pages 31 - 34, XP002461709

DOI:   http://dx.doi.org/10.1016/S8756-3282(99)00130-1
    - GINEBRA MP, "Mechanical and rheological improvement of a calcium phosphate cement by the addition of a polymeric drug", J BIOMED MATER RES, (2001), vol. 57, no. 1, pages 113 - 118, XP001562267
    - SARDA S, "Kinetic effect of citric acid influence on calcium phosphate bone cements as water reducing agent", J BIOMED MATER RES, (2002), vol. 61, pages 652 - 659
    - VAN DER HOUWEN, JAM ET AL., "The application of calcium phosphate precipitation chemistry to phosphorous recovery: the influence of organic ligands", ENVIRONMENTAL TECHNOLOGY, (2001), vol. 22, pages 1325 - 1335
    - BOHNER ET AL., "Effects of sulfate, pyrophosphate, and citrate ions on the physicochemical properties of cements made of P tricalcium phosphate", J AM CERAM SOC, (1996), vol. 79, no. 6, doi:doi:10.1111/j.1151-2916.1996.tb08746.x, pages 1427 - 34, XP000596067

DOI:   http://dx.doi.org/10.1111/j.1151-2916.1996.tb08746.x
    - GBURECK ET AL., "Surface properties of calcium phosphate particles for self setting bone cements", BIOMOLECULAR ENGINEERING, (2002), vol. 19, doi:doi:10.1016/S1389-0344(02)00010-2, pages 51 - 55, XP004378070

DOI:   http://dx.doi.org/10.1016/S1389-0344(02)00010-2
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.