EP1638969 - CGRP RECEPTOR ANTAGONISTS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 11.09.2009 Database last updated on 31.08.2024 | Most recent event Tooltip | 23.04.2010 | Lapse of the patent in a contracting state | published on 26.05.2010 [2010/21] | Applicant(s) | For all designated states Merck & Co., Inc. 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 / US | [2008/45] |
Former [2006/13] | For all designated states Merck & Co., Inc. 126 East Lincoln Avenue Rahway New Jersey 07065-0907 / US | Inventor(s) | 01 /
BURGEY, Christopher, S. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | 02 /
DENG, Zhengwu, J. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | 03 /
NGUYEN, Diem, N. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | 04 /
PAONE, Daniel, V. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | 05 /
SHAW, Anthony, W. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | 06 /
WILLIAMS, Theresa, M. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | [2006/13] | Representative(s) | Man, Jocelyn, et al Merck & Co., Inc. European Patent Department Merck Sharp & Dohme Limited Hertford Road, Hoddesdon Hertfordshire, EN11 9BU / GB | [N/P] |
Former [2006/48] | Man, Jocelyn, et al Merck & Co., Inc. European Patent Department Merck Sharp & Dohme Limited, Hertford Road, Hoddesdon Hertfordshire, EN11 9BU / GB | ||
Former [2006/13] | Man, Jocelyn Merck & Co.,Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR / GB | Application number, filing date | 04749887.8 | 09.04.2004 | [2006/13] | WO2004US10851 | Priority number, date | US20030463089P | 15.04.2003 Original published format: US 463089 P | US20030510352P | 10.10.2003 Original published format: US 510352 P | [2006/13] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2004092166 | Date: | 28.10.2004 | Language: | EN | [2004/44] | Type: | A2 Application without search report | No.: | EP1638969 | Date: | 29.03.2006 | Language: | EN | The application published by WIPO in one of the EPO official languages on 28.10.2004 takes the place of the publication of the European patent application. | [2006/13] | Type: | B1 Patent specification | No.: | EP1638969 | Date: | 05.11.2008 | Language: | EN | [2008/45] | Search report(s) | International search report - published on: | EP | 20.01.2005 | Classification | IPC: | C07D471/04, A61K31/4188, A61P25/06 | [2006/13] | CPC: |
C07D487/04 (EP,US);
C07D471/04 (EP,KR,US);
A61P1/02 (EP);
A61P1/04 (EP);
A61P11/00 (EP);
A61P11/06 (EP);
A61P13/10 (EP);
A61P17/00 (EP);
A61P19/02 (EP);
A61P25/00 (EP);
A61P25/04 (EP);
A61P25/06 (EP);
A61P25/08 (EP);
A61P25/30 (EP);
A61P27/02 (EP);
A61P27/16 (EP);
A61P29/00 (EP);
A61P3/10 (EP);
A61P31/04 (EP);
A61P37/08 (EP);
A61P43/00 (EP);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2006/13] | Extension states | AL | Not yet paid | HR | 15.11.2005 | LT | 15.11.2005 | LV | 15.11.2005 | MK | Not yet paid | Title | German: | CGRP-REZEPTORANTAGONISTEN | [2006/13] | English: | CGRP RECEPTOR ANTAGONISTS | [2006/13] | French: | ANTAGONISTES DES RECEPTEURS CGRP | [2006/13] | Entry into regional phase | 15.11.2005 | National basic fee paid | 15.11.2005 | Designation fee(s) paid | 15.11.2005 | Examination fee paid | Examination procedure | 18.10.2005 | Amendment by applicant (claims and/or description) | 15.11.2005 | Examination requested [2006/13] | 31.03.2008 | Communication of intention to grant the patent | 07.08.2008 | Fee for grant paid | 07.08.2008 | Fee for publishing/printing paid | Divisional application(s) | EP08105721.8 / EP2039694 | Opposition(s) | 06.08.2009 | No opposition filed within time limit [2009/42] | Fees paid | Renewal fee | 27.03.2006 | Renewal fee patent year 03 | 10.04.2007 | Renewal fee patent year 04 | 18.03.2008 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | MC | 30.04.2009 | [2010/21] | Cited in | International search | [A]WO0018764 (MERCK SHARP & DOHME [GB], et al) [A] 1-29 * claim 1 *; | [PA]WO03104236 (BRISTOL MYERS SQUIBB CO [US], et al) [PA] 1-29 * claim 1 *; | [A] - MALLEE J J ET AL, "Receptor Activity-modifying Protein 1 Determines the Species Selectivity of Non-peptide CGRP Receptor Antagonists", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (20020419), vol. 277, no. 16, ISSN 0021-9258, pages 14294 - 14298, XP002271313 [A] 1-29 * the whole document * DOI: http://dx.doi.org/10.1074/jbc.M109661200 | [A] - VAN ROSSUM, D., HANISCH, U.K. QUIRION, R., "Neuroanatomical Localization, Pharmcological Characterization and Functions of CGRP, related peptides and Their Receptors", NEUROSCIENCE AND BEHAVIORAL REVIEWS, (1997), vol. 21, no. 5, pages 649 - 678, XP002299339 [A] 1-29 * the whole document * DOI: http://dx.doi.org/10.1016/S0149-7634(96)00023-1 | by applicant | US4166452 | US4256108 | US4265874 | WO9635713 | - GOADSBY ET AL., ANN. NEUROL., (1990), vol. 28, pages 183 - 187 | - GOADSBY ET AL., ANN. NEUROL., (1988), vol. 23, pages 193 - 196 | - WILLIAMSON ET AL., CEPHALALGIA, (1997), vol. 17, pages 525 - 531 | - ESCOTT ET AL., BRAIN RES., (1995), vol. 669, pages 93 - 99 | - DOODS ET AL., BR. J. PHARMACOL., (2000), vol. 129, pages 420 - 423 | - OLESEN ET AL., N. ENGL. J. MED., (2004), vol. 350, pages 1104 - 1110 | - WILLIAMSON ET AL., "The CGRP Family: Calcitonin Gene-Related Peptide (CGRP), Amylin, and Adrenomedullin", LANDES BIOSCIENCE, (2000), pages 245 - 247 | - BURSTEIN ET AL., ANN. NEUROL., (2000), vol. 47, pages 614 - 624 | - DOODS, CURR OPIN INVES DRUGS, (2001), vol. 2, no. 9, pages 1261 - 1268 | - EDVINSSON ET AL., CEPHALALGIA, (1994), vol. 14, pages 320 - 327 | - ASHINA ET AL., NEUROLOGY, (2000), vol. 14, pages 1335 - 1340 | - YU ET AL., EUR. J. PHARM., (1998), vol. 347, pages 275 - 282 | - HULSEBOSCH ET AL., PAIN, (2000), vol. 86, pages 163 - 175 | - HOLZER, NEUROSCI., (1988), vol. 24, pages 739 - 768 | - DELAY-GOYET ET AL., ACTA PHYSIOL. SCANDA., (1992), vol. 146, pages 537 - 538 | - SALMON ET AL., NATURE NEUROSCI., (2001), vol. 4, no. 4, pages 357 - 358 | - MAY ET AL., CEPHALALGIA, (2002), vol. 22, pages 195 - 196 | - AWAWDEH ET AL., INT. ENDOCRIN. J., (2002), vol. 35, pages 30 - 36 | - MOLINA ET AL., DIABETES, (1990), vol. 39, pages 260 - 265 | - ZHANG ET AL., PAIN, (2001), vol. 89, page 265 | - FOSTER ET AL., ANN. NY ACAD. SCI., (1992), vol. 657, pages 397 - 404 | - SCHINI ET AL., AM. J. PHYSIOL., (1994), vol. 267, pages H2483 - H2490 | - ZHENG ET AL., J. VIROL., (1993), vol. 67, pages 5786 - 5791 | - BEER ET AL., CRIT. CARE MED., (2002), vol. 30, no. 8, pages 1794 - 1798 | - MENARD ET AL., J. NEUROSCI., (1996), vol. 16, no. 7, pages 2342 - 2351 | - CHEN ET AL., LANCET, (1993), vol. 342, page 49 | - SPETZ ET AL., J. UROLOGY, (2001), vol. 166, pages 1720 - 1723 | - WALLENGREN, CONTACT DERMATITIS, (2000), vol. 43, no. 3, pages 137 - 143 | - ROHRENBECK ET AL., NEUROBIOL. OF DISEASE, (1999), vol. 6, pages 15 - 34 | - HERZOG ET AL., J. MEMBRANE BIOLOGY, (2002), vol. 189, no. 3, page 225 | - HOFFMAN ET AL., SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, (2002), vol. 37, no. 4, pages 414 - 422 | - EDVINSSON ET AL., EUR. J PHARMACOL., (2001), vol. 415, pages 39 - 44 | - CHENG; PRUSOFF, BIOCHEM. PHARMACOL., (1973), vol. 22, pages 3099 - 3108 | - ARUNLAKSHANA; SCHILD, BR. J PHARMACOL., (1959), vol. 14, pages 48 - 58 | - HENNING ET AL., J. MED. CHEM., (1987), vol. 30, pages 814 - 819 | - BROWN ET AL., J. CHEM. SOC., (1957), pages 682 - 686 | - BARLIN ET AL., AUST. J. CHEM., (1982), vol. 35, no. 11, pages 2299 - 2306 | - J. CHEM. SOC., (1962), pages 3963 - 3968 | - TETRAHEDRON ASYMMETRY, (1998), pages 3381 - 94 | - J. ORG. CHEM., (1987), vol. 52, pages 2299 - 2301 |