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Extract from the Register of European Patents

EP About this file: EP1633864

EP1633864 - HIGH THROUGHPUT ASSAY OF LP-PLA2 ACTIVITY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.02.2011
Database last updated on 17.08.2024
Most recent event   Tooltip11.02.2011No opposition filed within time limitpublished on 16.03.2011  [2011/11]
Applicant(s)For all designated states
GLAXO GROUP LIMITED
Glaxo Wellcome House, Berkeley Avenue
Greenford, Middlesex UB6 0NN / GB
[N/P]
Former [2010/14]For all designated states
GLAXO GROUP LIMITED
Glaxo Wellcome House, Berkeley Avenue
Greenford, Middlesex UB6 ONN / GB
Former [2006/11]For all designated states
GLAXO GROUP LIMITED
Glaxo Wellcome House Berkeley Avenue
Greenford, Middlesex UB6 ONN / GB
Inventor(s)01 / HU, Yun-Fu
Five Moore Drive
Research Trangle Park, NC 27709 / US
02 / WALKER, George, T.
Five Moore Drive
Research Triangle Park, NC 27709 / US
 [2006/11]
Representative(s)Chiappinelli, Susan Ann
GlaxoSmithKline
Global Patents (CN925.1)
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[N/P]
Former [2006/11]Chiappinelli, Susan Ann
GlaxoSmithKline Corporate Intellectual Property 980 Great West Road (CN925.1)
Brentford, Middlesex TW8 9GS / GB
Application number, filing date04753533.127.05.2004
[2006/11]
WO2004US16716
Priority number, dateUS20030473777P28.05.2003         Original published format: US 473777 P
[2006/11]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2005001416
Date:06.01.2005
Language:EN
[2005/01]
Type: A2 Application without search report 
No.:EP1633864
Date:15.03.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 06.01.2005 takes the place of the publication of the European patent application.
[2006/11]
Type: B1 Patent specification 
No.:EP1633864
Date:07.04.2010
Language:EN
[2010/14]
Search report(s)International search report - published on:US17.03.2005
(Supplementary) European search report - dispatched on:EP12.05.2006
ClassificationIPC:C12N9/20, C12N15/09, C12Q1/34, C12Q1/56
[2006/11]
CPC:
G01N33/573 (EP,US); C12N9/20 (EP,US); C12Q1/44 (EP,US);
G01N2333/918 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/11]
Extension statesALNot yet paid
HR15.11.2005
LT15.11.2005
LV15.11.2005
MKNot yet paid
TitleGerman:LP-PLA2-AKTIVITÄTSTEST MIT HOHEM DURCHSATZ[2006/11]
English:HIGH THROUGHPUT ASSAY OF LP-PLA2 ACTIVITY[2006/11]
French:ESSAI POUR DETERMINER AVEC UN GRAND RENDEMENT L'ACTIVITE DE LA LP-PLA2[2006/11]
Entry into regional phase15.11.2005National basic fee paid 
15.11.2005Search fee paid 
15.11.2005Designation fee(s) paid 
15.11.2005Examination fee paid 
Examination procedure15.11.2005Amendment by applicant (claims and/or description)
15.11.2005Examination requested  [2006/11]
05.09.2006Despatch of a communication from the examining division (Time limit: M04)
22.12.2006Reply to a communication from the examining division
24.01.2007Despatch of a communication from the examining division (Time limit: M04)
16.05.2007Reply to a communication from the examining division
07.08.2007Despatch of a communication from the examining division (Time limit: M04)
26.11.2007Reply to a communication from the examining division
30.06.2008Despatch of a communication from the examining division (Time limit: M04)
24.10.2008Reply to a communication from the examining division
02.09.2009Communication of intention to grant the patent
22.12.2009Fee for grant paid
22.12.2009Fee for publishing/printing paid
Divisional application(s)EP10158845.7  / EP2253702
Opposition(s)10.01.2011No opposition filed within time limit [2011/11]
Fees paidRenewal fee
27.03.2006Renewal fee patent year 03
07.05.2007Renewal fee patent year 04
18.03.2008Renewal fee patent year 05
07.05.2009Renewal fee patent year 06
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Documents cited:Search[DX]  - TSELEPIS ALEXANDROS D ET AL, "PAF-degrading acetylhydrolase is preferentially associated with dense LDL and VHDL-1 in human plasma: Catalytic characteristics and relation to the monocyte-derived enzyme", ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, (1995), vol. 15, no. 10, ISSN 1079-5642, pages 1764 - 1773, XP002377512 [DX] 1-55 * sections headed "materials" and "acetylhydrolase assay" *
 [A]  - PALMANTIER R ET AL, "BIOSYNTHESIS OF PAF-ACETHER XIV. PAF-ACETHER OUTPUT IN MURINE PERITONEAL MACROPHAGES IS REGULATED BY THE LEVEL OF ACETYLHYDROLASE", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (1989), vol. 162, no. 1, ISSN 0006-291X, pages 475 - 482, XP009065539 [A] 1-55 * abstract *

DOI:   http://dx.doi.org/10.1016/0006-291X(89)92022-6
 [A]  - STAFFORINI D M ET AL, "Platelet - activating factor acetylhydrolase from human plasma", METHODS IN ENZYMOLOGY, ACADEMIC PRESS INC, SAN DIEGO, CA, US, (1990), vol. 187, ISSN 0076-6879, pages 344 - 357, XP002115202 [A] 1-55 * page 345, paragraph 2 - page 347, paragraph 4 *

DOI:   http://dx.doi.org/10.1016/0076-6879(90)87041-Z
 [A]  - PETROVIC NENAD ET AL, "A simple assay for a human serum phospholipase A2 that is associated with high-density lipoproteins", JOURNAL OF LIPID RESEARCH, (200110), vol. 42, no. 10, ISSN 0022-2275, pages 1706 - 1713, XP002377514 [A] 1-55 * abstract * * page 1710, column L, paragraph 1 - page 1711, column R, paragraph 2 *
International search[A]US5981252  (MACPHEE COLIN HOUSTON [GB], et al);
 [A]WO0032808  (AZWELL INC [JP], et al);
 [A]  - MIN J. ET AL., "Platelet Activating Factor Acetylhydrolases: Broad Substrate Specificity and Lipoprotein Binding does Not Modulate the Catalytic Properties of the Plasma Enzyme", BIOCHEMISTRY, (2001), vol. 40, no. 15, pages 4539 - 4549, XP002983176

DOI:   http://dx.doi.org/10.1021/bi002600g
 [A]  - KOSAKA T. ET AL., "Serum Platelet-Activating Factor Acetylhydrolase Activity in More Than 3000 Healthy Japanese", CLINICA CHIMICA ACTA, (2001), vol. 312, no. 1-2, pages 179 - 183, XP002983177
by applicant   - IMMUNOL. 15, (2000), vol. 164, no. 6, pages 3360 - 7
    - KHOVIDHUNKIT ET AL., METABOLISM., (1999), vol. 48, no. 12, pages 1524 - 31
    - SATOH ET AL., AM J RESPIR CRIT CARE MED., (1999), vol. 159, no. 3, pages 974 - 9
    - TSELEPIS ET AL., ARTHRITIS RHEUM., (1999), vol. 42, no. 2, pages 373 - 83
    - TSUJI ET AL., ORL J OTORHINOLARYNGOL RELAT SPEC., (1998), vol. 60, no. 1, pages 25 - 9
    - BELL ET AL., BIOCHEM BIOPHYS RES COMMUN., (1997), vol. 29-241, no. 3, pages 630 - 5 9
    - MUGURUMA ET AL., ADV EXP MED BIOL., (1997), vol. 407, pages 379 - 82
    - PEDIATR RES., (1993), vol. 34, no. 2, pages 237 - 41
    - PALMANTIER ET AL., "Biosynthesis of PAF-Acether XIV, PAF-Acether Output in Murine Peritoneal Macrophages is regulated by the level of acetylhydrolase", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATION., (1989), vol. 162, no. 1, doi:doi:10.1016/0006-291X(89)92022-6, pages 475 - 482, XP024842837

DOI:   http://dx.doi.org/10.1016/0006-291X(89)92022-6
    - STAFFORINI ET AL., "Platelet - activating factor acetylhydrolase from human plasma", METHODS IN ENZYMOLOGY, (1990), vol. 187, pages 344 - 357
    - PETROVIC ET AL., "A simple assay for a human serum phospholipase A2 that is associated with high-density lipoproteins", JOURNAL OF LIPID RESEARCH., (2001), vol. 42, no. 10, pages 1706 - 1713, XP002377514
    - KOSAKA ET AL., CLIN CHEM ACTA, (2000), vol. 296, no. 1-2, pages 151 - 61
    - KOSAKA ET AL., CLIN CHEM ACTA, (2001), vol. 312, no. 1-2, pages 179 - 83
    - TSELEPIS ET AL., ARTERIOSCLER THROMB VASC BIOL., (1995), vol. 15, no. 10, pages 1764 - 73
    - MIN ET AL., BIOCHEMISTRY, (2001), vol. 40, no. 15, pages 4539 - 4549
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.