EP1631661 - TRANSGENIC ANIMAL HAVING AN AMYLOID PRECURSOR PROTEIN WITH A MODIFIED BETA SECRETASE CLEAVAGE SITE [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 09.10.2009 Database last updated on 31.08.2024 | Most recent event Tooltip | 09.10.2009 | Application deemed to be withdrawn | published on 11.11.2009 [2009/46] | Applicant(s) | For all designated states Merck & Co., Inc. 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 / US | [N/P] |
Former [2006/10] | For all designated states Merck & Co., Inc. 126 East Lincoln Avenue Rahway New Jersey 07065-0907 / US | Inventor(s) | 01 /
CHEN, Richard, Z. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | 02 /
SIMON, Adam, J. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | 03 /
VOGT, Thomas, F. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | [2006/10] | Representative(s) | Man, Jocelyn, et al Merck & Co., Inc. European Patent Department Merck Sharp & Dohme Limited Hertford Road, Hoddesdon Hertfordshire, EN11 9BU / GB | [N/P] |
Former [2006/48] | Man, Jocelyn, et al Merck & Co., Inc. European Patent Department Merck Sharp & Dohme Limited, Hertford Road, Hoddesdon Hertfordshire, EN11 9BU / GB | ||
Former [2006/10] | Man, Jocelyn Merck & Co.,Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR / GB | Application number, filing date | 04753635.4 | 28.05.2004 | [2006/10] | WO2004US16836 | Priority number, date | US20030474772P | 30.05.2003 Original published format: US 474772 P | US20030518591P | 07.11.2003 Original published format: US 518591 P | [2006/10] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2004111189 | Date: | 23.12.2004 | Language: | EN | [2004/52] | Type: | A2 Application without search report | No.: | EP1631661 | Date: | 08.03.2006 | Language: | EN | The application published by WIPO in one of the EPO official languages on 23.12.2004 takes the place of the publication of the European patent application. | [2006/10] | Search report(s) | International search report - published on: | US | 31.03.2005 | (Supplementary) European search report - dispatched on: | EP | 07.07.2008 | Classification | IPC: | C12N5/00, C12N15/00, A01K67/00, G01N33/00 | [2006/10] | CPC: |
C07K14/4711 (EP,US);
A01K67/0275 (EP,US);
A01K67/0278 (EP,US);
C07K16/18 (EP,US);
C12N15/8509 (EP,US);
A01K2207/15 (EP,US);
A01K2217/00 (EP,US);
A01K2217/072 (EP,US);
A01K2227/105 (EP,US);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2006/10] | Extension states | AL | Not yet paid | HR | Not yet paid | LT | Not yet paid | LV | Not yet paid | MK | Not yet paid | Title | German: | TRANSGENES TIER MIT EINEM AMYLOID-VORLÄUFERPROTEIN MIT EINER MODIFIZIERTEN BETA-SECRETASE-SCHNITTSTELLE | [2006/10] | English: | TRANSGENIC ANIMAL HAVING AN AMYLOID PRECURSOR PROTEIN WITH A MODIFIED BETA SECRETASE CLEAVAGE SITE | [2006/10] | French: | ANIMAL TRANSGENIQUE COMPRENANT UNE PROTEINE PRECURSEUR AMYLOIDE PRESENTANT UN SITE DE CLIVAGE PAR LA BETA-SECRETASE MODIFIE | [2006/10] | Entry into regional phase | 30.12.2005 | National basic fee paid | 30.12.2005 | Search fee paid | 30.12.2005 | Designation fee(s) paid | 30.12.2005 | Examination fee paid | Examination procedure | 18.11.2005 | Amendment by applicant (claims and/or description) | 30.12.2005 | Examination requested [2006/10] | 08.10.2008 | Despatch of a communication from the examining division (Time limit: M06) | 21.04.2009 | Application deemed to be withdrawn, date of legal effect [2009/46] | 28.05.2009 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2009/46] | Fees paid | Renewal fee | 27.03.2006 | Renewal fee patent year 03 | 07.05.2007 | Renewal fee patent year 04 | 18.03.2008 | Renewal fee patent year 05 | 12.05.2009 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]WO9634097 (CEPHALON INC [US], et al); | [PX]WO03072041 (MERCK & CO INC [US], et al) [PX] 1-3,6 * claims 1,8-11 *; | [E]WO2004099376 (MERCK & CO INC [US], et al) [E] 1-10 * figures 4-8; claims 31-35 * | International search | [X]WO02094985 (MERCK & CO INC [US], et al); | [A] - MALLENDER W.D. ET AL., "Characterization of recombinant, soluble beta secretase from an insect cell expression system", MOLECULAR PHARMACOLOGY, (2001), vol. 59, no. 3, pages 619 - 626, XP001037766 | [A] - GAN L. ET AL., "The amyloid beta peptide primes the proapoptotic p53 patway and countreacts the antiapoptic function of its precursor protein", SOCIETY FOR NEUROSCIENCE ABSTRACTS, (2000), vol. 26, no. 1-2, XP008043353 | [A] - LI Y. ET AL., "Novel function assay for proteases and modulators: application in beta-secretase studies", MOLECULAR BIOTECHNOLOGY, (2001), vol. 18, pages 1 - 10, XP009024465 DOI: http://dx.doi.org/10.1385/MB:18:1:01 |