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Extract from the Register of European Patents

EP About this file: EP1615913

EP1615913 - PROCESS FOR PREPARING 2-(PYRIDINYL)METHYL SULFINYL-SUBSTITUTED BENZIMIDAZOLES AND NOVEL CHLORINATED DERIVATIVES OF PANTOPRAZOLE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  21.05.2010
Database last updated on 21.05.2024
Most recent event   Tooltip21.05.2010Application deemed to be withdrawnpublished on 23.06.2010  [2010/25]
Applicant(s)For all designated states
Teva Pharmaceutical Industries Limited
5 Basel Street, Box 3190
Petah Tikvah 49131 / IL
[2006/03]
Inventor(s)01 / LIBERMAN, Anita
14 Michael Neaman
Tel-Aviv, Israel / IL
02 / SINGER, Claude
8/8 David Elazar
Kfar Saba 44358 / IL
03 / RAIZI, Yuriy
34, Rishon le Zion Str.
Natanya 42374 / IL
04 / PILARSKY; Gideon
12/29 Atoroth
58487 Holon / IL
05 / BRAUDE, Viviana
18 Hanevel Street
60920 Kadima / IL
06 / FINKELSTEIN, Nina
Katzenelson Street 23B/17
46290 Herzliya / IL
07 / CHEN, Kobi
21 Beit Hilel Street
47291 Ramat HaSharon / IL
 [2006/17]
Former [2006/03]01 / LIBERMAN, Anita
Rechov Ben-Joseph 28
Tel-Aviv, Israel / IL
02 / SINGER, Claude
8/8 David Elazar
Kfar Saba 44358 / IL
03 / RAIZI, Yuriy
34, Rishon le Zion Str.
Natanya 42374 / IL
04 / PILARSKY; Gideon
12/29 Atoroth
58487 Holon / IL
05 / BRAUDE, Viviana
18 Hanevel Street
60920 Kadima / IL
06 / FINKELSTEIN, Nina
Katzenelson Street 23B/17
46290 Herzliya / IL
07 / CHEN, Kobi
21 Beit Hilel Street
47291 Ramat HaSharon / IL
Representative(s)Gallagher, Kirk James, et al
D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
[N/P]
Former [2006/03]Gallagher, Kirk James, et al
D Young & Co 120 Holborn
London EC1N 2DY / GB
Application number, filing date04755278.110.06.2004
[2006/03]
WO2004US19001
Priority number, dateUS20030477045P10.06.2003         Original published format: US 477045 P
US20030525851P01.12.2003         Original published format: US 525851 P
[2006/03]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004111029
Date:23.12.2004
Language:EN
[2004/52]
Type: A2 Application without search report 
No.:EP1615913
Date:18.01.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 23.12.2004 takes the place of the publication of the European patent application.
[2006/03]
Search report(s)International search report - published on:EP17.11.2005
ClassificationIPC:C07D401/12
[2006/03]
CPC:
C07D401/12 (EP,US); A61P1/04 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/03]
Extension statesALNot yet paid
HRNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON (PYRIDINYL)METHYL SULFINYL-SUBSTITUIERTE BENZIMIDAZOLES UND NEUE CHLORIERTE DERIVATE VON PANTOPRAZOLE[2007/46]
English:PROCESS FOR PREPARING 2-(PYRIDINYL)METHYL SULFINYL-SUBSTITUTED BENZIMIDAZOLES AND NOVEL CHLORINATED DERIVATIVES OF PANTOPRAZOLE[2006/03]
French:PROCEDE DE PREPARATION DE BENZIMIDAZOLES 2- (PYRIDINYL)METHYL SULFINYLE SUBSTITUES ET NOUVEAU DERIVES CHLORURES DE PANTOPRAZOLE[2007/46]
Former [2006/03]VERFAHREN ZUR HERSTELLUNG VON (PYRIDINYL)METHYL]SULFINYL-SUBSTITUIERTE BENZIMIDAZOLES UND NEUE CHLORIERTE DERIVATE VON PANTOPRAZOLE
Former [2006/03]PROCEDE DE PREPARATION DE BENZIMIDAZOLES 2- (PYRIDINYL)METHYL]SULFINYLE SUBSTITUES ET NOUVEAU DERIVES CHLORURES DE PANTOPRAZOLE
Entry into regional phase09.02.2005National basic fee paid 
09.02.2005Designation fee(s) paid 
09.02.2005Examination fee paid 
Examination procedure09.02.2005Amendment by applicant (claims and/or description)
09.02.2005Examination requested  [2006/03]
31.08.2007Despatch of a communication from the examining division (Time limit: M04)
10.01.2008Reply to a communication from the examining division
30.01.2008Observations by third parties
27.05.2008Despatch of a communication from the examining division (Time limit: M04)
03.06.2008Observations by third parties
15.09.2008Reply to a communication from the examining division
13.08.2009Despatch of a communication from the examining division (Time limit: M04)
24.12.2009Application deemed to be withdrawn, date of legal effect  [2010/25]
03.02.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2010/25]
Fees paidRenewal fee
12.06.2006Renewal fee patent year 03
14.06.2007Renewal fee patent year 04
25.03.2008Renewal fee patent year 05
16.06.2009Renewal fee patent year 06
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Cited inInternational search[X]US4758579  (KOHL BERNHARD [DE], et al) [X] 1,8-11,13-15,17,21,23,41-46,59 * example 6 *;
 [XA]WO9947514  (KNOLL AG [DE], et al) [X] 41-46 * example 5 * [A] 1-24,32-40,47-63;
 [XA]WO02062786  (TEVA PHARMA [IL], et al) [X] 41-46 * example 11 * [A] 1-24,32-40,47-63;
 [XA]EP1270555  (ESTEVE QUIMICA SA [ES]) [X] 41-46 * example 4 * [A] 1-24,32-40,47-63;
 [Y]WO03008406  (JANSSEN PHARMACEUTICA NV [BE], et al) [Y] 64-75 * page 8, line 22 - line 26 ** page 10, line 17 - line 25 *;
 [E]WO2004056804  (TEVA PHARMA [IL], et al) [E] 25,26,31 * page 7, line 8 - line 12 * * page 29, line 27 - page 30, line 26; examples 61-64 *;
 [X]  - KOHL B ET AL, "(H+,K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl] benzimidazoles. 4. A novel series of dimethoxypyridyl-substituted inhibitors with enhanced selectivity. The selection of pantoprazole as a clinical candidate", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (19920320), vol. 35, no. 6, ISSN 0022-2623, pages 1049 - 1057, XP002291720 [X] 1,8-11,13-15,17,21,23,41-49,59,25,31 * page 1055 first column under 'synthesis of sulfoxides by oxidation with aqueous alkaline sodium hypochlorite solution' * * page 1054, second column, under 'preparation of the sodium salt' *

DOI:   http://dx.doi.org/10.1021/jm00084a010
 [Y]  - BADWAN A A ET AL, "PANTOPRAZOLE SODIUM", ANALYTICAL PROFILES OF DRUG SUBSTANCES, (19970124), vol. 29, no. 1, pages 185 - 192, XP008031282 [Y] 64-75 * paragraph [4.4.2] *
otherUS4555518
 EP0997461
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