blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP1674452

EP1674452 - NOVEL 4-PHENYLAMINO-BENZALDOXIME DERIVATIVE AND USE THEREOF AS MEK INHIBITOR [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  23.01.2015
Database last updated on 19.10.2024
Most recent event   Tooltip23.01.2015Application deemed to be withdrawnpublished on 25.02.2015  [2015/09]
Applicant(s)For all designated states
CHUGAI SEIYAKU KABUSHIKI KAISHA
5-1, Ukima 5-chome, Kita-ku
Tokyo, 115-8543 / JP
[2006/26]
Inventor(s)01 / ISSHIKI, Yoshiaki, c/o CHUGAI SEIYAKU K.K.
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
02 / KOHCHI, Yasunori, c/o CHUGAI SEIYAKU K.K.
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
03 / HATTORI, Kazuo, c/o CHUGAI SEIYAKU K.K.
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
04 / SHIMMA, Nobuo, c/o CHUGAI SEIYAKU K.K.
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
05 / MIWA, Masanori, c/o CHUGAI SEIYAKU K.K.
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
06 / INAGAKI, Naohito, c/o CHUGAI SEIYAKU K.K.
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
07 / IIKURA, Hitoshi, c/o CHUGAI SEIYAKU K.K.
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
08 / MATSUBARA, Yasuaki, c/o CHUGAI SEIYAKU K.K.
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
 [2006/26]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2008/35]Vossius & Partner
Siebertstrasse 3
81675 München / DE
Former [2006/26]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date04773160.916.09.2004
[2006/26]
WO2004JP13501
Priority number, dateJP2003032918119.09.2003         Original published format: JP 2003329181
JP2003042466822.12.2003         Original published format: JP 2003424668
JP2004023433211.08.2004         Original published format: JP 2004234332
[2006/26]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2005028426
Date:31.03.2005
Language:EN
[2005/13]
Type: A1 Application with search report 
No.:EP1674452
Date:28.06.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 31.03.2005 takes the place of the publication of the European patent application.
[2006/26]
Search report(s)International search report - published on:JP31.03.2005
(Supplementary) European search report - dispatched on:EP11.09.2007
ClassificationIPC:C07C259/10, C07C229/58, C07C251/48, C07C311/04, C07C317/18, C07C323/12, C07D207/08, C07D207/26, C07D211/46, C07D213/30, C07D233/34, C07D233/64, C07D295/08, C07F7/18, A61K31/166, A61K45/00, A61P1/00, A61P1/16, A61P1/18, A61P3/10
[2006/26]
CPC:
C07D207/08 (EP,US); A61K31/166 (EP,US); A61P1/00 (EP);
A61P1/16 (EP); A61P1/18 (EP); A61P11/00 (EP);
A61P11/06 (EP); A61P13/08 (EP); A61P15/00 (EP);
A61P17/06 (EP); A61P19/02 (EP); A61P19/04 (EP);
A61P25/28 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P31/04 (EP); A61P31/12 (EP); A61P31/18 (EP);
A61P35/00 (EP); A61P37/00 (EP); A61P37/02 (EP);
A61P37/06 (EP); A61P43/00 (EP); A61P9/00 (EP);
A61P9/04 (EP); A61P9/08 (EP); A61P9/10 (EP);
C07C259/10 (EP,US); C07C311/04 (EP,US); C07C317/18 (EP,US);
C07C323/12 (EP,US); C07D207/27 (EP,US); C07D211/46 (EP,US);
C07D213/30 (EP,US); C07D233/32 (EP,US); C07D233/64 (EP,US);
C07D263/32 (EP,US); C07D295/088 (EP,US); C07D295/155 (EP,US);
C07F7/1804 (EP,US); C07C2601/02 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/26]
Extension statesALNot yet paid
HRNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:NEUES 4-PHENYLAMINOBENZALDOXIMDERIVATIE UND DESSEN VERWENDUNG ALS MEK-INHIBITOR[2006/26]
English:NOVEL 4-PHENYLAMINO-BENZALDOXIME DERIVATIVE AND USE THEREOF AS MEK INHIBITOR[2006/26]
French:NOUVEAU DERIVE DE 4-PHENYLAMINO-BENZALDOXIME ET SON UTILISATION EN TANT QU'INHIBITEUR DE MEK[2006/26]
Entry into regional phase07.04.2006Translation filed 
07.04.2006National basic fee paid 
07.04.2006Search fee paid 
07.04.2006Designation fee(s) paid 
07.04.2006Examination fee paid 
Examination procedure24.09.2004Request for preliminary examination filed
International Preliminary Examining Authority: JP
07.04.2006Examination requested  [2006/26]
20.06.2006Amendment by applicant (claims and/or description)
22.05.2012Despatch of a communication from the examining division (Time limit: M06)
12.11.2012Reply to a communication from the examining division
03.01.2013Despatch of a communication from the examining division (Time limit: M06)
11.07.2013Reply to a communication from the examining division
15.08.2013Despatch of a communication from the examining division (Time limit: M06)
25.02.2014Reply to a communication from the examining division
12.03.2014Despatch of a communication from the examining division (Time limit: M06)
23.09.2014Application deemed to be withdrawn, date of legal effect  [2015/09]
22.10.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/09]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.05.2012
Fees paidRenewal fee
07.04.2006Renewal fee patent year 03
28.09.2007Renewal fee patent year 04
20.03.2008Renewal fee patent year 05
23.09.2009Renewal fee patent year 06
27.09.2010Renewal fee patent year 07
22.09.2011Renewal fee patent year 08
20.09.2012Renewal fee patent year 09
20.09.2013Renewal fee patent year 10
26.09.2014Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[E]EP1780197  (CHUGAI PHARMACEUTICAL CO LTD [JP]) [E] 1-16,31-45,49-51* page 46 - page 50; example - *
International search[X]JP2003527379  ;
 [X]WO03051877  (BAYER AG [US], et al);
 [X]JPS59210046  (SEARLE & CO);
 [X]US4001420  (MALEN CHARLES, et al);
 [X]JPS4861448  ;
 [X]US2967187  (SERRES JR CARL, et al);
 [X]  - OZAKI K. ET AL., "Studies on 4(1H)-quinazolinones. 5. Synthesis and antiiflemmatory activity of 4(1H)-quinazolinone derivatives", JOURNAL OF MEDICINAL CHEMISTRY, (1985), vol. 28, no. 5, pages 568 - 576, XP002984298

DOI:   http://dx.doi.org/10.1021/jm50001a006
 [X]  - HEINTZ M. ET AL., "Electrosynthesis of aryl carboxylic acids from chlorobenzene derivatives and carbon dioxide", TETRAHEDRON, (1988), vol. 44, no. 6, pages 1631 - 1636, XP000673081

DOI:   http://dx.doi.org/10.1016/S0040-4020(01)86724-7
 [X]  - CHRDONNENS L. ET AL., "Fluorenacenes and fluorenaphthenes. Syntheses in the idenofluorene series. VIII. 3-methyl-, 1,4-dimethyl-, 1,3-dimethyl-, and 1,3,4-trimethyl-cis-fluorenacene", HELVETICA CHIMICA ACTA, (1958), vol. 41, pages 2436 - 2440, XP002903640

DOI:   http://dx.doi.org/10.1002/hlca.19580410753
Examination   - SOGA SHIRO ET AL, "KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (19990615), vol. 59, no. 12, ISSN 0008-5472, pages 2931 - 2938, XP002287485
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.