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EP1644500
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EP About this file: EP1644500
| EP1644500 - POLYCATIONIC COMPOSITIONS FOR CELLULAR DELIVERY OF POLYNUCLEOTIDES [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 19.06.2009 Database last updated on 26.07.2024 | Most recent event Tooltip | 19.06.2009 | Application deemed to be withdrawn | published on 22.07.2009 [2009/30] | Applicant(s) | For all designated states Sirna Therapeutics, Inc. 2950 Wilderness Place Boulder, CO 80301 / US | [2006/15] | Inventor(s) | 01 /
VARGEESE, Chandra 14010 Westhampton Place Broomfield, CO 80020 / US | 02 /
WEIMIN, Wang 3122 Cimarron Place Superior, CO 80027 / US | 03 /
CHEN, Tongqian 2450 Airport Road, Apt. 1284 Longmont, CO 80503 / US | 04 /
SWEEDLER, David 956 St. Andrews Lane Louisville, CO 80027 / US | 05 /
HAEBERLI, Peter 705 7th Street Berthoud, CO 80513 / US | [2006/15] | Representative(s) | Rollins, Anthony John, et al Merck Sharp & Dohme Limited European Patent Department Hertford Road Hoddesdon Hertfordshire EN11 9BU / GB | [N/P] |
| Former [2008/32] | Rollins, Anthony John, et al Merck Sharp & Dohme Limited European Patent Department Hertford Road Hoddesdon Hertfordshire EN11 9BU / GB | ||
| Former [2008/22] | Rollins, Anthony John, et al Merck Sharp & Dohme Limited Hertford Road Hoddesdon Herts EN11 9BU / GB | ||
| Former [2006/15] | Maschio, Antonio D Young & Co 120 Holborn London EC1N 2DY / GB | Application number, filing date | 04777833.7 | 09.07.2004 | [2006/15] | WO2004US21997 | Priority number, date | US20030485667P | 09.07.2003 Original published format: US 485667 P | US20030693059 | 23.10.2003 Original published format: US 693059 | US20030720448 | 24.11.2003 Original published format: US 720448 | US20040757803 | 14.01.2004 Original published format: US 757803 | US20040826966 | 16.04.2004 Original published format: US 826966 | WO2004US16390 | 24.05.2004 Original published format: PCT/US2004/016390 | [2006/15] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2005007854 | Date: | 27.01.2005 | Language: | EN | [2005/04] | Type: | A2 Application without search report | No.: | EP1644500 | Date: | 12.04.2006 | Language: | EN | The application published by WIPO in one of the EPO official languages on 27.01.2005 takes the place of the publication of the European patent application. | [2006/15] | Search report(s) | International search report - published on: | EP | 18.08.2005 | Classification | IPC: | C12N15/11 | [2006/15] | CPC: |
A61K47/645 (EP);
A61K49/0008 (EP);
C12N15/111 (EP);
C12N15/113 (EP);
C12N15/1137 (EP);
C12N15/1138 (EP);
C12N15/87 (EP);
C12Y103/01022 (EP);
C12Y604/01002 (EP);
A61K38/00 (EP);
C12N2310/14 (EP);
C12N2310/315 (EP);
C12N2310/317 (EP);
C12N2310/318 (EP);
C12N2310/321 (EP);
C12N2310/322 (EP);
C12N2310/332 (EP);
C12N2310/346 (EP);
| C-Set: |
C12N2310/321, C12N2310/3521 (EP)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2006/15] | Extension states | AL | Not yet paid | HR | Not yet paid | LT | Not yet paid | LV | Not yet paid | MK | Not yet paid | Title | German: | POLYKATIONISCHE ZUSAMMENSETZUNGEN FÜR DIE ZELLULÄRE FREISETZUNG VON POLYNUKLEOTIDEN | [2006/15] | English: | POLYCATIONIC COMPOSITIONS FOR CELLULAR DELIVERY OF POLYNUCLEOTIDES | [2006/15] | French: | COMPOSITIONS POLYCATIONIQUES DESTINEES A L'ADMINISTRATION CELLULAIRE DE POLYNUCLEOTIDES | [2006/15] | Entry into regional phase | 02.02.2006 | National basic fee paid | 02.02.2006 | Designation fee(s) paid | 02.02.2006 | Examination fee paid | Examination procedure | 02.02.2006 | Examination requested [2006/15] | 03.02.2009 | Application deemed to be withdrawn, date of legal effect [2009/30] | 06.03.2009 | Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2009/30] | Fees paid | Renewal fee | 27.07.2006 | Renewal fee patent year 03 | 27.07.2007 | Renewal fee patent year 04 | Penalty fee | Additional fee for renewal fee | 31.07.2008 | 05 M06 Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [DX]US2003125281 (LEWIS DAVID ET AL) [DX] 1 * paragraphs [0010] - [0012] *; | [X]WO0046187 (ORIDIGM CORPORATION; VERMEULIN, NICOLAAS, M., J; BURNS, MARK, R; WEBB,) [X] 1 * page 43, lines 10-21; claims 1-25 *; | [X] - MERDAN THOMAS ET AL, "Prospects for cationic polymers in gene and oligonucleotide therapy against cancer", ADVANCED DRUG DELIVERY REVIEWS, (20020913), vol. 54, no. 5, ISSN 0169-409X, pages 715 - 758, XP002324534 [X] 1 * page 715 - page 721 * DOI: http://dx.doi.org/10.1016/S0169-409X(02)00046-7 | [X] - BYK ETAL G, "Synthesis, activity and structure-activity relationship studies of novel cationic lipids for DNA transfer", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (19980115), vol. 41, no. 2, ISSN 0022-2623, pages 224 - 235, XP002118261 [X] 1 * the whole document * DOI: http://dx.doi.org/10.1021/jm9704964 | [X] - KICHLER A ET AL, "Intranasal gene delivery with a polyethylenimine-PEG conjugate", JOURNAL OF CONTROLLED RELEASE, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, (20020617), vol. 81, no. 3, ISSN 0168-3659, pages 379 - 388, XP004358078 [X] 1 * page 389 "2.1. Snthesis of PEI-PEG" and "2.3. DNA retadation assay ..." * DOI: http://dx.doi.org/10.1016/S0168-3659(02)00080-9 | [X] - WIGHTMAN L ET AL, "Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo", JOURNAL OF GENE MEDICINE, WILEY,, US, (200107), vol. 3, no. 4, ISSN 1099-498X, pages 362 - 372, XP002278348 [X] 1 * page 362 "Methods" and "Results" * DOI: http://dx.doi.org/10.1002/jgm.187 | [X] - BYK, GERARDO ET AL, "Genetic chemistry: tools for gene therapy coming from unexpected directions", DRUG DEVELOPMENT RESEARCH , 50(3/4), 566-572 CODEN: DDREDK; ISSN: 0272-4391, (2000), XP009046314 [X] 1 * the whole document * DOI: http://dx.doi.org/10.1002/1098-2299(200007/08)50:3/4<566::AID-DDR40>3.0.CO;2-A | [X] - NOVIKOVA E G ET AL, "EFFECT OF PUTRESCINE ON DNA COMPACTIZATION", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1991), Database accession no. PREV199293107784, XP002324533 [X] 1 * abstract * | [ ] - MOLEKULYARNAYA BIOLOGIYA (MOSCOW), (1991), vol. 25, no. 5, ISSN 0026-8984, pages 1207 - 1214 | [X] - LU BIAO ET AL, "Polyamine inhibition of estrogen receptor (ER) DNA-binding and ligand-binding functions", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (199804), Database accession no. PREV199800273709, XP002324532 [X] 1 * abstract * | [ ] - BREAST CANCER RESEARCH AND TREATMENT, (199804), vol. 48, no. 3, ISSN 0167-6806, pages 243 - 257 | [X] - YONEDA YUKIO ET AL, "Search for novel ligands selective at a polyamine recognition domain on the N-methyl-D-aspartate receptor complex using membrane binding techniques", BRAIN RESEARCH, (1995), vol. 679, no. 1, ISSN 0006-8993, pages 15 - 24, XP002324535 [X] 1 * the whole document * DOI: http://dx.doi.org/10.1016/0006-8993(95)00213-A | [PX] - INOUE, KEIJI ET AL, "Possible correlation between abilities of a variety of polyamines to increase activator protein-1 DNA binding and to inhibit [3H]spermidine transport in nuclear fractions of murine brain", BRAIN RESEARCH , 987(1), 126-130 CODEN: BRREAP; ISSN: 0006-8993, (2003), XP002324536 [PX] 1 * the whole document * DOI: http://dx.doi.org/10.1016/S0006-8993(03)03314-6 | [PX] - YINGYONGNARONGKUL, BOON-EK ET AL, "Solid-phase synthesis of 89 polyamine-based cationic lipids for DNA delivery to mammalian cells", CHEMISTRY--A EUROPEAN JOURNAL , 10(2), 463-473 CODEN: CEUJED; ISSN: 0947-6539, (2004), XP002324537 [PX] 1 * the whole document * DOI: http://dx.doi.org/10.1002/chem.200305232 |