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Extract from the Register of European Patents

EP About this file: EP1653992

EP1653992 - USE OF A VEGF ANTAGONIST IN COMBINATION WITH RADIATION THERAPY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.06.2008
Database last updated on 15.06.2024
Most recent event   Tooltip27.06.2008Application deemed to be withdrawnpublished on 30.07.2008  [2008/31]
Applicant(s)For all designated states
REGENERON PHARMACEUTICALS, INC.
777 Old Saw Mill River Road
Tarrytown, NY 10591 / US
For all designated states
THOMAS JEFFERSON UNIVERSITY
1020 Walnut Avenue Philadelphia
Pennsylvania 19107 / US
[N/P]
Former [2006/19]For all designated states
REGENERON PHARMACEUTICALS, INC.
777 Old Saw Mill River Toad
Tarrytown, NY 10591 / US
For all designated states
THOMAS JEFFERSON UNIVERSITY
1020 Walnut Avenue Philadelphia
Pennsylvania 19107 / US
Inventor(s)01 / HOLASH, Jocelyn
321 Channing Way
Alameda, CA 94502 / US
02 / YANCOPOULOS, George
1519 Baptist Church Road
Yorktown Heights, NY 10598 / US
03 / WACHSBERGER, Phyllis R.
Bodine Building, Room G302B, 111 South 11th Street
Philadelphia, PA 19107 / US
04 / DICKER, Adam, P.
418 Silver Hill Road
Cherry Hill, NJ 08002 / US
05 / BURD, Randy
219 Sugartown Road
Wayne, PA 19087 / US
 [2006/19]
Representative(s)Bentham, Andrew
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2006/19]Bentham, Andrew
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Application number, filing date04779673.530.07.2004
[2006/19]
WO2004US24675
Priority number, dateUS20030492864P06.08.2003         Original published format: US 492864 P
[2006/19]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2005016369
Date:24.02.2005
Language:EN
[2005/08]
Type: A1 Application with search report 
No.:EP1653992
Date:10.05.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 24.02.2005 takes the place of the publication of the European patent application.
[2006/19]
Search report(s)International search report - published on:EP24.02.2005
ClassificationIPC:A61K38/18, A61K45/00, A61P35/00
[2006/19]
CPC:
A61K41/00 (EP,US); A61K38/179 (EP,US); A61P35/00 (EP);
A61P37/02 (EP)
C-Set:
A61K38/179, A61K2300/00 (EP,US);
A61K41/00, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/19]
Extension statesALNot yet paid
HRNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:VERWENDUNG EINES VEGF-ANTAGONISTEN IN KOMBINATION MIT STRAHLENTHERAPIE[2006/19]
English:USE OF A VEGF ANTAGONIST IN COMBINATION WITH RADIATION THERAPY[2006/19]
French:UTILISATION D'UN ANTAGONISTE DES VEGF EN COMBINAISON AVEC UNE RADIOTHERAPIE[2006/19]
Entry into regional phase06.02.2006National basic fee paid 
06.02.2006Designation fee(s) paid 
06.02.2006Examination fee paid 
Examination procedure04.03.2005Request for preliminary examination filed
International Preliminary Examining Authority: US
06.02.2006Amendment by applicant (claims and/or description)
06.02.2006Examination requested  [2006/19]
26.09.2007Despatch of a communication from the examining division (Time limit: M04)
07.02.2008Application deemed to be withdrawn, date of legal effect  [2008/31]
12.03.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2008/31]
Fees paidRenewal fee
27.07.2006Renewal fee patent year 03
27.07.2007Renewal fee patent year 04
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Cited inInternational search[X]EP1179541  (UNIV TEXAS [US]) [X] 1,4-11,14-18 * page 17, line 11 - line 23 * * page 74, line 42 - line 46 *;
 [XY]WO02060489  (REGENERON PHARMA [US], et al) [X] 18 * sentence 9 - sentence 19; figures 13A,14A * * page 40, lines 21-24; example 30 * [Y] 1-17;
 [XY]WO02070008  (IMCLONE SYSTEMS INC [US], et al) [X] 1,4-11,14-17 * page 55, paragraphs 251-255 * [Y] 1-17;
 [PX]WO03068155  (UNIV VANDERBILT [US], et al) [PX] 1,4-11,14-18 * page 5, line 1 - page 6, line 25 * * page 38, line 18 - page 39, line 33 *;
 [XY]  - WACHSBERGER PHYLLIS ET AL, "Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: exploring mechanisms of interaction.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. JUN 2003, (200306), vol. 9, no. 6, ISSN 1078-0432, pages 1957 - 1971, XP002300697 [X] 1,5,6,9,10 * page 1962, column 2 - page 1963, column 1; table 2 * [Y] 1-17
 [Y]  - HOLASH JOCELYN ET AL, "VEGF-Trap: A VEGF blocker with potent antitumor effects", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (20020820), vol. 99, no. 17, ISSN 0027-8424, pages 11393 - 11398, XP002300698 [Y] 1-17 * page 11396, column 1 - page 11397, column 2 *

DOI:   http://dx.doi.org/10.1073/pnas.172398299
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.