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Extract from the Register of European Patents

EP About this file: EP1663202

EP1663202 - SUBSTITUTED INDOLES AS INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE (PARP) [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  23.08.2013
Database last updated on 14.09.2024
Most recent event   Tooltip23.08.2013Application deemed to be withdrawnpublished on 25.09.2013  [2013/39]
Applicant(s)For all designated states
Aventis Pharmaceuticals Inc.
55 Corporate Drive
Bridgewater, NJ 08807 / US
[2012/03]
Former [2006/44]For all designated states
Aventis Pharmaceuticals, Inc.
300 Somerset Corporate Boulevard
Bridgewater, New Jersey 08807 / US
Former [2006/23]For all designated states
Aventis Pharmaceuticals, Inc.
300 Somerset Corporate Boulevard
Bridgewater, New Jersey 08807-2854 / US
Inventor(s)01 / JIANG, John, Z.
5 Lane Road
Hillsborough, NJ 08844 / US
02 / KOEHL, Jack, R.
168 Aster Court
Whitehouse Station, NJ 08889 / US
03 / MEHDI, Shujaath
43 N. 14th Avenue, Apt. 2
Manville, NJ 08835 / US
04 / MOORCROFT, Neil
603 Route 173
Bloomsbury, NJ 08804 / US
05 / MUSICK, Kwon, Yon
13 Hidden Pond Court
Raritan, NJ 08869 / US
06 / WEINTRAUB, Philip, M.
33 Casale Drive South
Warren, New Jersey 07059 / US
07 / EASTWOOD, Paul, R.
Calle Palencia,33, 2-1
08191 Rubi, Barcelona / ES
 [2006/32]
Former [2006/23]01 / JIANG, John, Z.
5 Lane Road
Hillsborough, NJ 08844 / US
02 / KOEHL, Jack, R.
168 Aster Court
Whitehouse Station, NJ 08889 / US
03 / MEHDI, Shujaath
43 N. 14th Avenue, Apt. 2
Manville, NJ 08835 / US
04 / MOORCROFT, Neil
603 Route 173
Bloomsbury, NJ 08804 / US
05 / MUSICK, Kwon, Yon
13 Hidden Pond Court
Raritan, NJ 08869 / US
06 / WEINTRAUB, Philip, M.
33 Casale Drive South
Warren, New Jersey 07059 / US
07 / EASTWOOD, Paul, R.
Calle Alcalde de Mostoles 7, 4 1
E-08025 Barcelona / ES
Representative(s)Adamson Jones
Park View House
58 The Ropewalk
Nottingham NG1 5DW / GB
[N/P]
Former [2011/52]Adamson Jones
BioCity Nottingham
Pennyfoot Street
Nottingham NG1 1GF / GB
Former [2006/23]Morel-Pécheux, Muriel
Aventis Pharma SA, Direction Brevets, 20, avenue Raymond Aron
92165 Antony Cedex / FR
Application number, filing date04782937.901.09.2004
[2006/23]
WO2004US28543
Priority number, dateUS20030500039P04.09.2003         Original published format: US 500039 P
[2006/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2005023246
Date:17.03.2005
Language:EN
[2005/11]
Type: A1 Application with search report 
No.:EP1663202
Date:07.06.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 17.03.2005 takes the place of the publication of the European patent application.
[2006/23]
Search report(s)International search report - published on:EP17.03.2005
ClassificationIPC:A61K31/404, A61P9/10, A61K31/541, A61K31/55, A61K31/496, A61K31/454, C07D209/40, C07D401/12, C07D409/04, C07D401/04, C07D471/04, C07D405/12, C07D403/04, C07D401/10, C07D403/10
[2006/23]
CPC:
C04B35/632 (EP,US); A61K31/496 (EP,KR,US); A61K31/404 (EP,US);
A61K31/454 (EP,US); A61K31/4745 (EP,US); A61K31/503 (EP,US);
A61K31/5377 (EP,US); A61K31/541 (EP,US); A61K31/55 (EP,US);
A61P13/12 (EP); A61P19/02 (EP); A61P19/10 (EP);
A61P21/00 (EP); A61P21/04 (EP); A61P25/00 (EP);
A61P25/02 (EP); A61P25/04 (EP); A61P25/14 (EP);
A61P25/16 (EP); A61P25/28 (EP); A61P27/02 (EP);
A61P3/10 (EP); A61P31/18 (EP); A61P35/00 (EP);
A61P37/00 (EP); A61P37/08 (EP); A61P43/00 (EP);
A61P9/10 (EP); C07D209/40 (EP,US); C07D401/04 (EP,KR,US);
C07D401/10 (EP,US); C07D401/12 (EP,US); C07D403/04 (EP,US);
C07D403/10 (EP,US); C07D405/12 (EP,US); C07D405/14 (EP,US);
C07D409/04 (EP,US); C07D471/04 (EP,KR,US); C07D487/08 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/23]
Extension statesAL04.04.2006
HR04.04.2006
LT04.04.2006
LV04.04.2006
MK04.04.2006
TitleGerman:SUBSTITUTIERTE INDOLE ALS INHIBITOREN DER POLY (ADP-RIBOSE) POLYMERASE (PARP)[2006/23]
English:SUBSTITUTED INDOLES AS INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE (PARP)[2006/23]
French:INDOLES SUBSTITUES COMME INHIBITEURS DE POLYMERASE DE POLY(ADP-RIBOSE) (PARP)[2006/23]
Entry into regional phase04.04.2006National basic fee paid 
04.04.2006Designation fee(s) paid 
04.04.2006Examination fee paid 
Examination procedure31.05.2005Request for preliminary examination filed
International Preliminary Examining Authority: EP
03.04.2006Amendment by applicant (claims and/or description)
04.04.2006Examination requested  [2006/23]
18.01.2010Despatch of a communication from the examining division (Time limit: M06)
27.07.2010Reply to a communication from the examining division
03.04.2013Application deemed to be withdrawn, date of legal effect  [2013/39]
06.05.2013Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2013/39]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  18.01.2010
Fees paidRenewal fee
11.09.2006Renewal fee patent year 03
12.09.2007Renewal fee patent year 04
31.03.2008Renewal fee patent year 05
11.09.2009Renewal fee patent year 06
14.09.2010Renewal fee patent year 07
30.09.2011Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
30.09.201209   M06   Not yet paid
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Cited inInternational search[X]DE2707268  (HOECHST AG) [X] 22 * page 21 - page 23; examples 32-35 * * page 26 - page 27; example 42; table 3 * * figure III; claim 2 *;
 [X]US4148895  (LATTRELL RUDOLF, et al) [X] 22 * column 9 - column 10; table 1 * * claim - *;
 [A]WO0185687  (BASF AG [DE], et al) [A] 1-23 * abstract * * example - ** claim - *;
 [PX]  - BENKLI, KADRIYE ET AL, "Synthesis and antimicrobial activities of some imidazole substituted indoles", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 2004:84341, URL: STN, XP002311566 [PX] 22 * abstract *
 [PX]  - PLAYER, MARK R. ET AL, "1,3-Oxazino[4,5-b]indole-2,4-(1H,9H)-diones and 5,6- dimethylpyrrolo[2,3-d]-1,3-oxazin-2,4-(1H,7H)-diones as serine protease inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 4(7), 949-54 CODEN: BMCLE8; ISSN: 0960-894X, (1994), XP002311564 [PX] 22 * page 950 - page 951; examples 4F,G,H; table 1 *

DOI:   http://dx.doi.org/10.1016/S0960-894X(01)80270-5
 [X]  - PLAYER, MARK R. ET AL, "Synthesis of 1,3-disubstituted 2-amino-5-hydroxyindoles by reductive aromatization", JOURNAL OF HETEROCYCLIC CHEMISTRY , 30(1), 125-8 CODEN: JHTCAD; ISSN: 0022-152X, (1993), XP002311565 [X] 22 * page 125; examples I-IV,D *

DOI:   http://dx.doi.org/10.1002/jhet.5570300122
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