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EP About this file: EP1687405

EP1687405 - TTBKS AS MODIFIERS OF THE BETA CATENIN PATHWAY AND METHODS OF USE [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 30.05.2008 Database last updated on 27.07.2024
Most recent event Tooltip	30.05.2008	Application deemed to be withdrawn	published on 02.07.2008 [2008/27]
Applicant(s)	For all designated states Exelixis, Inc. 170 Harbor Way, P.O. Box 511 South San Francisco, CA 94083-0511 / US
	[2006/32]
Inventor(s)	01 / FRANCIS-LANG, Helen 1782 Pacific Avenue, Apt. 2 San Francisco, CA 94109 / US
	02 / WINTER, Christopher, G. 34 Kimball Street Needham, MA 02492 / US
	03 / VENTURA, Richard, Benn, Abegania 290 Bay Ridge Drive Daly City, CA 94014 / US
	04 / ZHANG, Haiguang 4833 El Grande Place El Sobrante, CA 94803 / US
	05 / HEUER, Timothy, S. 315 Avenue Del Oro El Granada, California 94018 / US
	[2006/32]
Representative(s)	Main, Malcolm Charles Murgitroyd & Company Scotland House 165-169 Scotland Street Glasgow G5 8PL / GB
	[N/P]
Former [2006/32]	Main, Malcolm Charles Murgitroyd & Company Scotland House 165-169 Scotland Street Glasgow G5 8PL / GB
Application number, filing date	04812396.2	23.11.2004
	[2006/32]
	WO2004US39864
Priority number, date	US20030524587P	24.11.2003 Original published format: US 524587 P
	[2006/32]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2005052134
	Date:	09.06.2005
	Language:	EN
	[2005/23]
	Type:	A2 Application without search report
	No.:	EP1687405
	Date:	09.08.2006
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 09.06.2005 takes the place of the publication of the European patent application.
	[2006/32]
Search report(s)	International search report - published on:	US	28.09.2006
	(Supplementary) European search report - dispatched on:	EP	01.10.2007
Classification	IPC:	C12Q1/00, C12Q1/68, G01N33/53, C12Q1/48, G01N33/50, G01N33/574	[2007/32]
	CPC:	C12Q1/485 (EP,US); A61P31/00 (EP); A61P35/00 (EP); A61P43/00 (EP); A61P9/00 (EP); G01N33/573 (EP,US); (+) G01N33/57496 (EP,US); G01N2500/00 (EP,US); G01N2510/00 (EP,US) (-)
	Former IPC [2006/47]	C12Q1/00, C12Q1/68, G01N33/53
	Former IPC [2006/32]	C12N1/00
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2006/32]
Extension states	AL	11.05.2006
	HR	11.05.2006
	LT	11.05.2006
	LV	11.05.2006
	MK	11.05.2006
	YU	11.05.2006
Title	German:	TTBKS ALS MODIFIKATOREN DES BETA-CATENIN-WEGS SOWIE VERWENDUNGSVERFAHREN	[2006/32]
	English:	TTBKS AS MODIFIERS OF THE BETA CATENIN PATHWAY AND METHODS OF USE	[2006/32]
	French:	TAU-TUBULINE KINASES UTILISEES COMME MODIFICATEURS DE LA VOIE DE LA BETA-CATENINE ET LEURS PROCEDES D'UTILISATION	[2006/32]
Entry into regional phase	11.05.2006	National basic fee paid
	11.05.2006	Search fee paid
	11.05.2006	Designation fee(s) paid
	11.05.2006	Examination fee paid
Examination procedure	11.05.2006	Examination requested [2006/32]
	04.12.2006	Amendment by applicant (claims and/or description)
	02.01.2008	Application deemed to be withdrawn, date of legal effect [2008/27]
	11.02.2008	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2008/27]
Fees paid	Renewal fee
	14.11.2006	Renewal fee patent year 03
	Penalty fee
	Additional fee for renewal fee
	30.11.2007	04 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X] - LESORT M ET AL, "Glycogen synthase kinase-3ss, ss-catenin, and tau in postmortem bipolar brain", JOURNAL OF NEURAL TRANSMISSION, SPRINGER VERLAG, VIENNA, AT, (1999), vol. 106, no. 11-12, ISSN 0300-9564, pages 1217 - 1222, XP002981251 [X] 1-31 * the whole document * * In particular: p. 1217, abstract; p. 1221, last paragraph. * DOI: http://dx.doi.org/10.1007/s007020050235
		[X] - ANDERTON BRIAN H ET AL, "Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?", MOLECULAR MEDICINE TODAY, (200002), vol. 6, no. 2, ISSN 1357-4310, pages 54 - 59, XP002439984 [X] 1-31 * the whole document * * In particular: p. 54, abstract; p. 54, col. 1, l. 1 - p. 55, col. 2, l. 5. * DOI: http://dx.doi.org/10.1016/S1357-4310(99)01640-8
		[X] - STOOTHOFF WILLIAM H ET AL, "Axin negatively affects tau phosphorylation by glycogen synthase kinase 3beta.", JOURNAL OF NEUROCHEMISTRY, (200211), vol. 83, no. 4, ISSN 0022-3042, pages 904 - 913, XP002439985 [X] 1-31 * the whole document * * In particular: p. 904, abstract; p. 905, col. 1-col. 2, bridging paragraph; p. 907, col. 2, last paragraph - p. 909, col. 1, first pargraph. * DOI: http://dx.doi.org/10.1046/j.1471-4159.2002.01197.x
		[X] - DAVIES G ET AL, "THE INTERACTION BETWEEN BETA-CATENIN, GSK3BETA AND APC AFTER MOTOGEN INDUCED CELL-CELL DISSOCIATION<,> AND THEIR INVOLVEMENT IN SIGNAL TRANSDUCTION PATHWAYS IN PROSTATE CANCER", INTERNATIONAL JOURNAL OF ONCOLOGY, EDITORIAL ACADEMY OF THE INTERNATIONAL JOURNAL OF ONCOLOGY,, GR, (200104), vol. 18, no. 4, ISSN 1019-6439, pages 843 - 847, XP009055625 [X] 1-31 * the whole document * * In particular: p. 843, abstract; p. 844, material and methods; p. 845-846, discussion. *
		[X] - JACKSON G R ET AL, "Human Wild-type Tau Interacts with wingless Pathway Components and Produces Neurofibrillary Pathology in Drosophila", NEURON, CELL PRESS, (20020506), vol. 34, ISSN 0896-6273, pages 509 - 519, XP002984591 [X] 1-31 * the whole document * * In particular: p. 509, abstract; p. 514, col. 2, second paragraph. * DOI: http://dx.doi.org/10.1016/S0896-6273(02)00706-7
		[X] - LAU K-F ET AL, "Molecular Cloning and Characterization of the Human Glycogen Synthase Kinase-3beta Promoter", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, (19990901), vol. 60, no. 2, ISSN 0888-7543, pages 121 - 128, XP004444813 [X] 1-31 * the whole document * * In particular: p. 121, abstract; p. 122, material and methods; p. * DOI: http://dx.doi.org/10.1006/geno.1999.5875
		[A] - TOMIZAWA^A K ET AL, "Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL, (20010316), vol. 492, no. 3, ISSN 0014-5793, pages 221 - 227, XP004257367 [A] 1-31 * the whole document * DOI: http://dx.doi.org/10.1016/S0014-5793(01)02256-6
	International search	[X]US2002015943 (BIENZ MARIANN [GB]);
		[X]US2003108937 (WILLIAMSON MARK [US]);
		[Y] - HUDZIAK ET AL., "Resistance of morpholino phosphorodiamidate oligomers to enzymatic degradation", ANTISENSE NUCLEIC ACID DRUG DEVELOPMENT, (1996), vol. 6, pages 267 - 272, XP002135296
		[Y] - ANGELES ET AL., "Enzyme-linked immunosorbent assay for trkA tyrosine kinase activity", ANALYTICAL BIOCHEMISTRY, (1996), vol. 236, doi:doi:10.1006/abio.1996.0130, pages 49 - 55, XP002128805 DOI: http://dx.doi.org/10.1006/abio.1996.0130

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