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EP1655302
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EP About this file: EP1655302
| EP1655302 - ANTIPARASITIC ARTEMISININ DERIVATIVES (ENDOPEROXIDES) [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 31.07.2009 Database last updated on 24.08.2024 | Most recent event Tooltip | 31.07.2009 | Application deemed to be withdrawn | published on 02.09.2009 [2009/36] | Applicant(s) | For all designated states The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong / CN | [2008/10] |
| Former [2006/19] | For all designated states Bayer HealthCare AG 51368 Leverkusen / DE | Inventor(s) | 01 /
Haynes, Richard, K. Hong Kong Univ. of Science and Technology House 2 1University Road Clear Water Bay Kowloon / HK | 02 /
Lam, William, Wai-Lun 6/F 100 Shantung Street Mongkok Kowloon / HK | 03 /
Chan, Dennis, Ho Wai Flat 15, 2nd Floor Kam Yung House Kam Fung Court Ma On Shan New Territories / HK | 04 /
Tsang, Hing-Wo 10A, To Shek Village Sha Tin New Territories / HK | 05 /
Cheung, Man-Ki Flat B, 7th Floor, Le Cachet, No 69, Sing Woo Road Happy Valley, Hong Kong / HK | 06 /
Greif, Gisela Marienhöhe 15 53424 Remagen / DE | 07 /
Schmuck, Gabriele Am Ringofen 17 42327 Wuppertal / DE | 08 /
Voerste, Arnd Mozartstrasse 3-5 50674 Köln / DE | [2006/19] | Representative(s) | Arends, William Gerrit, et al Marks & Clerk LLP 15 Fetter Lane London EC4A 1BW / GB | [N/P] |
| Former [2008/33] | Arends, William Gerrit, et al Marks & Clerk 90 Long Acre London WC2E 9RA / GB | ||
| Former [2008/10] | Arends, William Gerrit, et al Marks & Clerk 90 Long Acre London WC2E 9RA / GB | Application number, filing date | 05017342.6 | 14.07.1999 | [2006/19] | Priority number, date | EP19980305596 | 14.07.1998 Original published format: EP 98305596 | [2006/19] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP1655302 | Date: | 10.05.2006 | Language: | EN | [2006/19] | Type: | A3 Search report | No.: | EP1655302 | Date: | 23.08.2006 | [2006/34] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 24.07.2006 | Classification | IPC: | C07D493/18, A61K31/335, A61K31/35 | [2006/19] | CPC: |
A61K31/355 (EP,US);
C07D493/18 (EP,KR,US);
A61K31/352 (KR);
A61K31/4025 (EP,KR,US);
A61K31/4178 (EP,KR,US);
A61K31/422 (EP,KR,US);
A61K31/427 (EP,KR,US);
A61K31/452 (EP,KR,US);
A61K31/496 (EP,KR,US);
A61K31/5377 (EP,KR,US);
A61K31/541 (EP,KR,US);
A61K31/55 (EP,KR,US);
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2006/19] | Extension states | RO | 23.02.2007 | SI | 23.02.2007 | Title | German: | ANTIPARASITISCHE ARTEMISININ DERIVATE (ENDOPEROXIDE) | [2006/19] | English: | ANTIPARASITIC ARTEMISININ DERIVATIVES (ENDOPEROXIDES) | [2006/19] | French: | DERIVES D'ARTEMISININE ANTIPARASITAIRES (ENDOPEROXYDES) | [2006/19] | Examination procedure | 23.02.2007 | Examination requested [2007/14] | 23.03.2007 | Despatch of a communication from the examining division (Time limit: M06) | 17.08.2007 | Reply to a communication from the examining division | 22.10.2008 | Communication of intention to grant the patent | 02.03.2009 | Fee for grant paid | 02.03.2009 | Fee for publishing/printing paid | 03.03.2009 | Application deemed to be withdrawn, date of legal effect [2009/36] | 07.04.2009 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2009/36] | Parent application(s) Tooltip | EP99933043.4 / EP1095042 | Fees paid | Renewal fee | 12.12.2005 | Renewal fee patent year 03 | 12.12.2005 | Renewal fee patent year 04 | 12.12.2005 | Renewal fee patent year 05 | 12.12.2005 | Renewal fee patent year 06 | 12.12.2005 | Renewal fee patent year 07 | 31.07.2006 | Renewal fee patent year 08 | 31.07.2007 | Renewal fee patent year 09 | 31.03.2008 | Renewal fee patent year 10 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]EP0362730 (HOECHST AG [DE]) [X] 1-27 * column W *; | [X]EP0456149 (HOECHST AG [DE]) [X] 1-27 * column W *; | [Y]WO9308195 (UNIV SYDNEY [AU]) [Y] 1-27 * column W *; | [X]US5225562 (MCCHESNEY JAMES D [US], et al) [X] 1-27 * column W *; | [X]CN1122806 (SHANGHAI INST MATERIA MEDICA [CN]) [X] 1-27 * column W *; | [PX]WO9933461 (HAUSER INC [US], et al) [PX] 1-27 * column W *; | [X] - JEFFORD,C.W., "Peroxidic Antimalarials", ADV.DRUG RES., LONDON, (1997), vol. 29, pages 271 - 325, XP002119844 [X] 1-27 * see page 320, 2nd par., last sentence *; column W * | [X] - MESHNICK S R ET AL, "ARTEMISININ AND THE ANTIMALARIAL ENDOPEROXIDES: FROM HERBAL REMEDY TO TARGETED CHEMOTHERAPY", MICROBIOLOGICAL REVIEWS, (19960601), vol. 60, no. 2, pages 301 - 315, XP002052313 [X] 1-27 * see page 306, right col.,last par. *; column W * | [YX] - TONMUNPHEAN,S. ET AL., "Comparative molecular field analysis of artemisinin derivatives: Ab initio versus semiempirical optimized structures", J.COMP.-AIDED MOL.DES., AMSTERDAM, (1998), vol. 12, pages 397 - 409, XP002120343 [Y] 1-15,20 * see p.402,fig. 2 *; column W * [X] 16-25 DOI: http://dx.doi.org/10.1023/A:1008002602653 | [X] - LUO ET AL, "The Chemistry, Pharmacology, and Clinicla Applications of Qinghaosu (Artemisinin) and Its Derivatives", MEDICINAL RESEARCH REVIEWS, (19870101), vol. 7, no. 1, ISSN 0198-6325, pages 29 - 57, XP002088809 [X] 1-27 * column W * | [Y] - YONG-HUA Y ET AL, "Artemisinin derivatives with 12-aniline substitution: synthesis and antimalarial activity", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (19950817), vol. 5, no. 16, ISSN 0960-894X, page 1791-1794, XP004135366 [Y] 1-27 * column W * DOI: http://dx.doi.org/10.1016/0960-894X(95)00297-7 | [Y] - PU ET AL., "Synthesis and Antimalarial Activities of Several Fluorinated Artemisinin Derivatives", JOURNAL OF MEDICINAL CHEMISTRY, (19950101), vol. 38, no. 20, ISSN 0022-2623, pages 4120 - 4124, XP002089611 [Y] 1-27 * column W * DOI: http://dx.doi.org/10.1021/jm00020a028 | [X] - JUNG, M. ET AL., "A Concise Synthesis of Novel Aromatic Analogs of Artemisinin", HETEROCYCLES, SENDAI, (1997), vol. 45, no. 6, pages 1055 - 1058, XP002120565 [X] 1-27 * column W * | [PX] - POSNER, G.H., "Antimalarial peroxides in the quinghaosu (artesimin) and yingzhaosu families", EXP.OPIN.THER.PATENTS, LONDON, (199811), vol. 8, no. 11, pages 1487 - 1493, XP002119814 [PX] 1-15,20 * column W * DOI: http://dx.doi.org/10.1517/13543776.8.11.1487 | [X] - SOON, H. W. ET AL., "Direct Conversion of Pyranose Anomeric OH-to-F-to-R in the Artemisinin Family of Antimalarial Trioxanes", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, (19980319), vol. 39, no. 12, ISSN 0040-4039, pages 1533 - 1536, XP004108092 [X] 16 * Scheme I. * DOI: http://dx.doi.org/10.1016/S0040-4039(98)00132-4 |