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Extract from the Register of European Patents

EP About this file: EP1621198

EP1621198 - Substituted carbostyril derivatives as 5-HT 1A receptor subtype agonists [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  03.10.2014
Database last updated on 20.11.2024
Most recent event   Tooltip16.01.2015Lapse of the patent in a contracting state
???moredetails.lapse.edited??? CH, LI
published on 18.02.2015  [2015/08]
Applicant(s)For all designated states
OTSUKA PHARMACEUTICAL CO., LTD.
9, Kandatsukasa-cho 2-chome Chiyoda-ku
Tokyo 101-8535 / JP
[2006/05]
Inventor(s)01 / Uwahodo, Yasufumi
70-8, Aza Miyanomae, Oujincho Furukawa
Tokushima-shi, Tokushima 771-1151 / JP
02 / Jordan, Shaun
3641 Byron Place, Urbana, Frederick
Maryland, MD21704 / US
03 / Kikuchi, Tetsuro
157-13, Kawauchicho Komatsunishi
Tokushima-shi, Tokushima 771-0104 / JP
04 / Tottori, Katsura
15-1, Kamirokujo, Kamiitacho
Itano-gun, Tokushima 771-1345 / JP
05 / Hirose, Tsuyoshi
8-9-502.Sako Ichibancho
Tokushima-shi, Tokushima 770-0021 / JP
 [2006/05]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[N/P]
Former [2008/31]HOFFMANN EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Former [2006/05]HOFFMANN EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
D-81925 München / DE
Application number, filing date05023971.429.01.2002
[2006/05]
Priority number, dateUS2001077021029.01.2001         Original published format: US 770210
[2006/05]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1621198
Date:01.02.2006
Language:EN
[2006/05]
Type: A3 Search report 
No.:EP1621198
Date:12.04.2006
[2006/15]
Type: B1 Patent specification 
No.:EP1621198
Date:23.05.2007
Language:EN
[2007/21]
Search report(s)(Supplementary) European search report - dispatched on:EP28.02.2006
ClassificationIPC:A61K31/496, A61K45/06, A61P25/18, A61P25/28
[2006/43]
CPC:
A61K31/00 (EP); A61K31/496 (EP,KR); A61K45/06 (EP);
A61P1/08 (EP); A61P15/00 (EP); A61P15/10 (EP);
A61P25/00 (EP); A61P25/02 (EP); A61P25/06 (EP);
A61P25/14 (EP); A61P25/16 (EP); A61P25/18 (EP);
A61P25/20 (EP); A61P25/24 (EP); A61P25/28 (EP);
A61P25/30 (EP); A61P25/32 (EP); A61P3/04 (EP);
A61P39/02 (EP); A61P43/00 (EP) (-)
C-Set:
A61K31/496, A61K2300/00 (EP)
Former IPC [2006/14]A61K31/00, A61K31/496, A61K45/06, A61P25/24, A61P25/18, A61P25/28, A61P25/16, A61P25/06, A61P25/30, A61P15/00, A61P3/04, A61P1/08
Former IPC [2006/05]A61K31/496, A61P25/18
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2006/05]
TitleGerman:Substituierte Carbostyrilderivate als 5-HT1A-Subtyp Agonisten[2006/05]
English:Substituted carbostyril derivatives as 5-HT 1A receptor subtype agonists[2006/05]
French:Dérivés substitués de carbostyril comme agonistes du sous-type du récepteur 5-HT1A[2006/05]
Examination procedure03.11.2005Examination requested  [2006/05]
27.07.2006Amendment by applicant (claims and/or description)
28.07.2006Despatch of a communication from the examining division (Time limit: M04)
10.08.2006Reply to a communication from the examining division
05.10.2006Communication of intention to grant the patent
22.01.2007Fee for grant paid
22.01.2007Fee for publishing/printing paid
Parent application(s)   TooltipEP02716434.2  / EP1355639
Divisional application(s)EP06015782.3  / EP1712225
Opposition(s)Opponent(s)01  22.02.2008  22.04.2008  ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
5 Basel Street, P.O. Box 3190
Petah Tiqva 49131 / IL
Opponent's representative
Prins, Hendrik Willem, et al, et al
Arnold & Siedsma
PO Box 18558
2502 EN The Hague / NL
 02  25.02.2008  22.04.2008  ADMISSIBLE
STADA Arzneimittel AG
Stadastrasse 2-18
61118 Bad Vilbel / DE
Opponent's representative
Wittkopp, Alexander, et al, et al
Maiwald Patentanwalts- und
Rechtsanwaltsgesellschaft mbH
Jungfernstieg 38
20354 Hamburg / DE
 [N/P]
Former [2011/02]
Opponent(s)01  22.02.2008  22.04.2008  ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
5 Basel Street, P.O. Box 3190
Petah Tiqva 49131 / IL
Opponent's representative
Prins, Hendrik Willem, et al, et al
Arnold & Siedsma PO Box 18558
2502 EN The Hague / NL
 02  25.02.2008  22.04.2008  ADMISSIBLE
STADA Arzneimittel AG
Stadastrasse 2-18
61118 Bad Vilbel / DE
Opponent's representative
Wittkopp, Alexander, et al, et al
Maiwald Patentanwalts GmbH Jungfernstieg 38
20354 Hamburg / DE
Former [2010/02]
Opponent(s)01  22.02.2008  22.04.2008  ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
5 Basel Street, P.O. Box 3190
Petah Tiqva 49131 / IL
Opponent's representative
Prins, Hendrik Willem, et al, et al
Bird & Bird LLP P.O. Box 30311
2500 GH Den Haag / NL
 02  25.02.2008  22.04.2008  ADMISSIBLE
STADA Arzneimittel AG
Stadastrasse 2-18
61118 Bad Vilbel / DE
Opponent's representative
Wittkopp, Alexander, et al, et al
Maiwald Patentanwalts GmbH Jungfernstieg 38
20354 Hamburg / DE
Former [2008/15]
Opponent(s)01  22.02.2008   
Teva Pharmaceutical Industries Ltd.
5 Basel Street, P.O. Box 3190
Petah Tiqva 49131 / IL
Opponent's representative
Prins, Hendrik Willem, et al, et al
Arnold & Siedsma Sweelinckplein 1
2517 GK The Hague / NL
 02  25.02.2008    ADMISSIBLE
STADA Arzneimittel AG
Stadastrasse 2-18
61118 Bad Vilbel / DE
Opponent's representative
Wittkopp, Alexander, et al, et al
Maiwald Patentanwalts GmbH Jungfernstieg 38
20354 Hamburg / DE
Former [2008/14]
Opponent(s)01  25.02.2008   
Stada R & D GmbH
Stadastrasse 2 - 18
61118 Bad Vilbel / DE
Opponent's representative
Wittkopp, Alexander, et al, et al
Maiwald Patentanwalts GmbH Jungfernstieg 38
20354 Hamburg / DE
25.04.2008Invitation to proprietor to file observations on the notice of opposition
31.10.2008Reply of patent proprietor to notice(s) of opposition
18.01.2010Date of oral proceedings
19.02.2010Despatch of interlocutory decision in opposition
19.02.2010Despatch of minutes of oral proceedings
08.07.2014Legal effect of revocation of patent [ N /P ]
08.07.2014Legal effect of revocation of patent [2014/45]
01.09.2014Despatch of communication that the patent will be revoked
Appeal following opposition28.04.2010Appeal received No.  T0801/10
29.06.2010Statement of grounds filed
08.07.2014Result of appeal procedure: revocation of the patent
16.04.2010Appeal received No.  T0801/10
29.06.2010Statement of grounds filed
08.07.2014Result of appeal procedure: revocation of the patent
08.07.2014Date of oral proceedings
22.07.2014Minutes of the oral proceedings despatched
Fees paidRenewal fee
24.11.2005Renewal fee patent year 03
24.11.2005Renewal fee patent year 04
24.11.2005Renewal fee patent year 05
25.01.2007Renewal fee patent year 06
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCH23.05.2007
LI23.05.2007
[2015/08]
Former [2010/16]deleted
Former [2009/02]CY29.01.2008
Documents cited:Search[DA]US4734416  (BANNO KAZUO [JP], et al) [DA] 1,2,4-10 * abstract * * column 1, lines 5-60 * * column 2, line 49 - column 3, line 22 * * column 6, lines 41,42 * * column 29, lines 15-24 * * column 33, line 1 * * examples 54,205,233,258,294 * * claims 21,28 *;
 [DX]EP0367141  (OTSUKA PHARMA CO LTD [JP]) [DX] 1,2,4-10 * abstract * * page 3, line 4 - line 7 * * page 3, line 29 - line 36 * * example 1 * * claims 12,13,22,23,26-28,31-33 *;
 [A]US5691330  (NAKAO TOHRU [JP], et al) [A] 1,2,4-10 * page 2, line 39 - line 67 * * column 3, line 28 - column 4, line 10 *;
 [A]WO9938864  (AMERICAN HOME PROD [US]) [A] 1-10 * abstract * * page 1, line 6 - line 11 * * page 6, line 1 * * page 6, line 16 - line 24 *;
 [YA]  - LIEBERMAN JEFFREY A, "Atypical antipsychotic drugs as a first-line treatment of schizophrenia: A rationale and hypothesis.", JOURNAL OF CLINICAL PSYCHIATRY, (1996), vol. 57, no. SUPPL. 11, ISSN 0160-6689, pages 68 - 71, XP008005973 [Y] 1,2,4-10 * abstract * * tables 2,3 * * page 69, column 2, paragraph 1 - paragraph 2 * * page 70, column 1, paragraph 2 * [A] 1-10
 [YA]  - MELTZER H Y ET AL, "SINGLE OR MULTIPLE RECEPTOR TARGETS: WHICH ARE BEST FOR ANTIPSYCHOTIC DRUGS", NEUROPSYCHOPHARMACOLOGY, ELSEVIER SCIENCE PUBLISHING, NEW YORK, NY, US, (200008), vol. 23, no. S02, ISSN 0893-133X, page S73, XP008029267 [Y] 1,2,4-10 [A] 1-10
 [A]  - INOUE T ET AL, "EFFECTS OF THE NOVEL ANTIPSYCHOTIC AGENT 7-{4--(2,3-DICHLOROPHENYL)-1 PIPERAZINYL-1-PIPERAZINYLBUTYLOXYü-3,4-DIHYDRO-2(1H)-QUINOLINONE (OPC-14597) ON PROLACTIN RELEASE FROM THE RAT ANTERIOR PITUITARY GLAND", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMERICAN SOCIETY FOR PHARMACOLOGY AND, US, (199604), vol. 277, no. 1, ISSN 0022-3565, pages 137 - 143, XP008005978 [A] * page 142, column 1, paragraph L *
 [A]  - PRINSSEN ERIC P M ET AL, "Interactions between neuroleptics and 5-HT1A ligands in preclinical behavioral models for antipsychotic and extrapyramidal effects.", PSYCHOPHARMACOLOGY, (199905), vol. 144, no. 1, ISSN 0033-3158, pages 20 - 29, XP002209298 [A] 1-6,8 * abstract * * page 20, column 2, paragraph 1 - page 21, column 1, paragraph 2 * * page 25, column 2, paragraph 2 - page 26, column 1, paragraph 1 * * page 26, column 1, paragraph 3 - column 2, paragraph 2 * * page 27, column 1, paragraph 2 - paragraph 3 * * page 27, column 2, paragraph 3 *

DOI:   http://dx.doi.org/10.1007/s002130050972
 [A]  - UWAHODO YASUFUMI ET AL, "Pharmacological profile of OPC-14597, a novel antipsychotic drug (2): Weak extrapyramidal side effects.", JAPANESE JOURNAL OF PHARMACOLOGY, 68th Annual Meeting of the Japanese Pharmacological Society;Nagoya, Japan; March 25-28, 1995, (1995), vol. 67, no. SUPPL. 1, ISSN 0021-5198, page 144P, XP001237224 [A] 1,2,4-10 * the whole document *
 [PX]  - GARCIA-NANYA M., APIQUIAN R., FRESAN A., "Atypical antipsychotics: Review article [Los antipsycoticos atipicos: Una revision]", SALUD MENTAL, (200110), vol. 24, no. 5, pages 37 - 43, XP008005976 [PX] 1-10 * abstract * * page 38, column 2, paragraph 2 - paragraph 4 * * page 39, column 2, paragraph 4 *
 [PA]  - JORDAN S ET AL, "IN VIVO EFFECTS OF ARIPIPRAZOLE ON DOPAMINERGIC AND SEROTONERGIC FUNCTION IN RAT PREFRONTAL CORTEX AND STRIATUM", SOCIETY FOR NEUROSCIENCE ABSTRACTS, SOCIETY FOR NEUROSCIENCE, US, (2001), vol. 2, no. 27, ISSN 0190-5295, page 2327,AN87503, XP008005982 [PA] * the whole document *
 [PA]  - SUMIYOSHI T ET AL, "Tandospirone, a serotonin-1A agonist, added to neuroleptic treatment enhances cognitive performance in schizophrenia", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (2001), Database accession no. PREV200200022926, XP002364564 [PA] * abstract *
    [ ] - SOCIETY FOR NEUROSCIENCE ABSTRACTS, 31ST ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; SAN DIEGO, CALIFORNIA, USA; NOVEMBER 10-15, 2001, (2001), vol. 27, no. 2, ISSN 0190-5295, page 2586
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