blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP1713502

EP1713502 - HIGHLY CONCENTRATED LIQUID FORMULATIONS OF ANTI-EGFR ANTIBODIES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  11.04.2014
Database last updated on 07.10.2024
Most recent event   Tooltip11.04.2014Application deemed to be withdrawnpublished on 14.05.2014  [2014/20]
Applicant(s)For all designated states
Merck Patent GmbH
Frankfurter Strasse 250
64293 Darmstadt / DE
[2006/43]
Inventor(s)01 / MATHEUS, Susanne
Realschulstrasse 19
54347 Neumagen-Dhron / DE
02 / MAHLER, Hanns-Christian
Buschungstrasse 54a
65205 Wiesbaden / DE
 [2006/43]
Application number, filing date05701212.227.01.2005
[2006/43]
WO2005EP00797
Priority number, dateUS20040543549P12.02.2004         Original published format: US 543549 P
[2006/43]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report
No.:WO2005077414
Date:25.08.2005
Language:DE
[2005/34]
Type: A1 Application with search report 
No.:EP1713502
Date:25.10.2006
Language:DE
The application published by WIPO in one of the EPO official languages on 25.08.2005 takes the place of the publication of the European patent application.
[2006/43]
Search report(s)International search report - published on:EP25.08.2005
ClassificationIPC:A61K39/395, A61K9/08, A61P35/00
[2006/43]
CPC:
A61K9/08 (EP,US); A61K39/395 (KR); A61P15/00 (EP);
A61P17/06 (EP); A61P19/02 (EP); A61P27/02 (EP);
A61P29/00 (EP); A61P3/10 (EP); A61P31/18 (EP);
A61P35/00 (EP); A61P35/04 (EP); A61P37/02 (EP);
A61P37/04 (EP); A61P9/00 (EP); C07K16/2863 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/43]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
LV03.07.2006
MKNot yet paid
YUNot yet paid
TitleGerman:HOCHKONZENTRIERTE, FLÜSSIGE FORMULIERUNGEN VON ANTI-EGFR-ANTIKÖRPERN[2006/43]
English:HIGHLY CONCENTRATED LIQUID FORMULATIONS OF ANTI-EGFR ANTIBODIES[2006/43]
French:FORMULATIONS LIQUIDES FORTEMENT CONCENTREES D'ANTICORPS ANTI-EGFR[2006/43]
Entry into regional phase03.07.2006National basic fee paid 
03.07.2006Designation fee(s) paid 
03.07.2006Examination fee paid 
Examination procedure03.07.2006Examination requested  [2006/43]
13.05.2008Despatch of a communication from the examining division (Time limit: M06)
19.11.2008Reply to a communication from the examining division
07.12.2011Despatch of a communication from the examining division (Time limit: M04)
12.04.2012Reply to a communication from the examining division
01.08.2013Despatch of a communication from the examining division (Time limit: M04)
12.12.2013Application deemed to be withdrawn, date of legal effect  [2014/20]
08.01.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2014/20]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  13.05.2008
Fees paidRenewal fee
12.01.2007Renewal fee patent year 03
14.01.2008Renewal fee patent year 04
14.01.2009Renewal fee patent year 05
13.01.2010Renewal fee patent year 06
14.01.2011Renewal fee patent year 07
11.01.2012Renewal fee patent year 08
10.01.2013Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
31.01.201410   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[X]WO03007988  (MERCK PATENT GMBH [DE], et al) [X] 8,9,12-20 * page 4 *;
 [X]WO03053465  (MERCK PATENT GMBH [DE], et al) [X] 8,9,12-20 * page 4 * * pages 5-6 * * examples 3-5 *;
 [Y]WO02096457  (NOVARTIS AG [CH], et al) [Y] 1-20 * page 4 * * pages 8,10,17 * * examples 2,7,8,10 *;
 [Y]WO2004001007  (IDEC PHARMA CORP [US], et al) [Y] 1-20 * pages 2-3 * * pages 6,11 * * pages 14-16 * * pages 20-23 *;
 [Y]US6252055  (RELTON JULIAN MARCUS [GB]) [Y] 1-20 * columns 2,5 * * examples 1,2 *;
 [Y]CH684164  (ROTKREUZSTIFTUNG ZENTRALLAB) [Y] 1-20 * pages 4-5 *;
 [YP]WO2004085474  (IMCLONE SYSTEMS INC [US], et al) [YP] 1-20 * page 23 *;
 [YP]  - HARRIS REED J ET AL, "Commercial manufacturing scale formulation and analytical characterization of therapeutic recombinant antibodies", DRUG DEVELOPMENT RESEARCH, (200403), vol. 61, no. 3, ISSN 0272-4391, pages 137 - 154, XP002324970 [YP] 1-20 * pages 145-147 *

DOI:   http://dx.doi.org/10.1002/ddr.10344
 [T]  - VAN REIS, ZYDNEY, In Encyclopedia of bioprocess technology: fermentation, biocatalysis and bioseparation, WILEY & SONS, (1999), XP009046105 [T] 1-20 * page 2197 - page 2214 *
Examination   - HARDING JOANNE ET AL, "Cetuximab: an epidermal growth factor receptor chemeric human-murine monoclonal antibody.", DRUGS OF TODAY (BARCELONA, SPAIN : 1998) FEB 2005 LNKD- PUBMED:15821783, (200502), vol. 41, no. 2, ISSN 1699-3993, pages 107 - 127
    - SUSANNE MATHEUS ET AL, "A Critical Evaluation of Tm(FTIR) Measurements of High-Concentration IgG1 Antibody Formulations as a Formulation Development Tool", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, (20060621), vol. 23, no. 7, doi:10.1007/S11095-006-0283-9, ISSN 1573-904X, pages 1617 - 1627, XP019405151

DOI:   http://dx.doi.org/10.1007/s11095-006-0283-9
    - SRIDHAR S S ET AL, "Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancer", LANCET ONCOLOGY, LANCET PUBLISHING GROUP, LONDON, GB, (20030701), vol. 4, no. 7, doi:10.1016/S1470-2045(03)01137-9, ISSN 1470-2045, pages 397 - 406, XP004809825

DOI:   http://dx.doi.org/10.1016/S1470-2045(03)01137-9
    - FRACASSO-PM ET AL, "A study to assess the pharmacokinetics (PK) and pharmacodynamics (PD) of a single infusion of cetuximab (IMC-C225).", PROC AM SOC CLIN ONCOL, (ABSTR 787), vol. 22, (20111201), 2003 ASCO Annual Meeting
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.