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Extract from the Register of European Patents

EP About this file: EP1760152

EP1760152 - PROCESS FOR PRODUCING DIPEPTIDE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  14.08.2009
Database last updated on 14.09.2024
Most recent event   Tooltip14.08.2009Application deemed to be withdrawnpublished on 16.09.2009  [2009/38]
Applicant(s)For all designated states
KYOWA HAKKO KOGYO CO., LTD.
6-1, Ohtemachi 1-chome Chiyoda-ku
Tokyo 100-8185 / JP
[2007/10]
Inventor(s)01 / HASHIMOTO, Shin-ichi c/o Technical res. lab
1-1, Kyowa-cho, Hofu-shi
Yamaguchi 747-8522 / JP
02 / TABATA, Kazuhiko c/o BioFrontier Lab.
6-6, Asahi-machi 3-chome, Machida-shi
Tokyo 194-8533 / JP
03 / NOGUCHI, Ayako c/o Head Office, Kyowa Hakko Kogyo
6-1, Ohtemachi 1-chome, Chiyoda-ku
Tokyo 100-8185 / JP
04 / ADACHI, Yugo c/o Technical res. lab.
1-1, Kyowa-cho, Hofu-shi
Yamaguchi 747-8522 / JP
 [2007/10]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2008/35]Vossius & Partner
Siebertstrasse 3
81675 München / DE
Former [2007/10]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date05734655.321.04.2005
[2007/10]
WO2005JP07626
Priority number, dateJP2004012548621.04.2004         Original published format: JP 2004125486
[2007/10]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2005103260
Date:03.11.2005
Language:EN
[2005/44]
Type: A1 Application with search report 
No.:EP1760152
Date:07.03.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 03.11.2005 takes the place of the publication of the European patent application.
[2007/10]
Search report(s)International search report - published on:JP03.11.2005
(Supplementary) European search report - dispatched on:EP05.07.2007
ClassificationIPC:C12N15/52, C12N1/21, C12N9/00, C12P21/02
[2007/10]
CPC:
C07K5/06043 (EP,US); C07K5/06026 (EP,US); C07K5/06078 (EP,US);
C07K5/12 (EP,US); C12N9/00 (EP,US); C12N9/93 (EP,US);
C12P21/02 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/10]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
LVNot yet paid
MKNot yet paid
YUNot yet paid
TitleGerman:VERFAHREN ZUR DIPEPTIDHERSTELLUNG[2007/10]
English:PROCESS FOR PRODUCING DIPEPTIDE[2007/10]
French:PROCÉDÉ SERVANT À PRODUIRE UN DIPEPTIDE[2007/10]
Entry into regional phase21.11.2006Translation filed 
21.11.2006National basic fee paid 
21.11.2006Search fee paid 
21.11.2006Designation fee(s) paid 
21.11.2006Examination fee paid 
Examination procedure21.11.2006Amendment by applicant (claims and/or description)
21.11.2006Examination requested  [2007/10]
25.09.2007Despatch of a communication from the examining division (Time limit: M06)
07.04.2008Reply to a communication from the examining division
14.11.2008Despatch of a communication from the examining division (Time limit: M04)
25.03.2009Application deemed to be withdrawn, date of legal effect  [2009/38]
28.04.2009Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2009/38]
Fees paidRenewal fee
27.04.2007Renewal fee patent year 03
28.02.2008Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
30.04.200905   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]WO0058478  (HOLLAND SWEETENER CO [NL], et al) [X] 1-20 * claim 1 *;
 [E]EP1616963  (KYOWA HAKKO KOGYO KK [JP]) [E] 1-20* sequences 47, 48 *;
 [X]  - TUZUN ISIL ET AL, "2-Amino-N-(2-furylmethyl)propanamide as a novel alanylglycine equivalent synthesized by bacilysin synthetase.", ENZYME AND MICROBIAL TECHNOLOGY, (20031008), vol. 33, no. 5, ISSN 0141-0229, pages 725 - 728, XP002362113 [X] 1-20 * page 726, column L; figure 2 *

DOI:   http://dx.doi.org/10.1016/S0141-0229(03)00209-6
 [X]  - ZAWADZKE L E ET AL, "Existence of two D-alanine ligases in Escherichia coli: cloning and sequencing of the ddlA gene and purification and characterization of the DdlA and DdlB enzymes", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, (1991), vol. 30, ISSN 0006-2960, pages 1673 - 1682, XP002998304 [X] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1021/bi00220a033
 [X]  - NEUHAUS F C, "The enzymatic synthesis of D-alanyl-D-alanine. I. Purification and properties of D-alanyl-D-alanine synthetase.", THE JOURNAL OF BIOLOGICAL CHEMISTRY MAR 1962, (196203), vol. 237, ISSN 0021-9258, pages 778 - 786, XP002437387 [X] 1-20 * page 779, column L; table 1 *
 [X]  - STENESH J J ET AL, "Carnosine-anserine synthetase of muscle. 4. Partial purification of the enzyme and further studies of beta-alanyl peptide synthesis.", THE BIOCHEMICAL JOURNAL DEC 1960, (196012), vol. 77, no. 3, ISSN 0264-6021, pages 575 - 581, XP002437388 [X] 1-20 * page 576, column L *
 [X]  - STEIN C ET AL, "An in vitro characterization of [gamma]-glutamylhistamine synthetase: A novel enzyme catalyzing histamine metabolism in the central nervous system of the marine mollusk, Aplysia californica", JOURNAL OF NEUROCHEMISTRY 1982 UNITED KINGDOM, (1982), vol. 38, no. 1, pages 204 - 214, XP009085180 [X] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1111/j.1471-4159.1982.tb10873.x
International search[X]WO2004000879  (COMMISSARIAT ENERGIE ATOMIQUE [FR], et al);
 [X]  - LAUTRU S. ET AL, "The albonoursin gene Cluster of S noursei biosynthesis of diketopiperazine metabolites independent of nonribosomal peptide synthetases.", CHEM BIOL., (2002), vol. 9, no. 12, pages 1355 - 1364, XP002242438

DOI:   http://dx.doi.org/10.1016/S1074-5521(02)00285-5
 [Y]  - KANZAKI H. ET AL, "Enzymatic conversion of cyclic dipeptides to dehydro derivatives that inhibit cell division.", J BIOSCI BIOENG., (2000), vol. 90, no. 1, pages 86 - 89, XP002242437
 [A]  - KANZAKI H.ET AL, "Effective production of dehydro cyclic dipeptide albonoursin exhibiting pronuclear fusion inhibitory activity. I. Taxonomy and fermentation.", J ANTIBIOT., (1999), vol. 52, no. 11, pages 1017 - 1022, XP002934394
 [A]  - KANZAKI H. ET AL, "Biosynthetic intermediates of the tetradehydro cyclic dipeptide albonoursin produced by Streptomyces albulus KO-23.", J ANTIBIOT., (2000), vol. 53, no. 11, pages 1257 - 1264, XP001149049
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