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EP1747023 - METHODS AND COMPOSITIONS FOR REDUCING HCV VIRAL GENOME AMOUNTS IN A TARGET CELL [Right-click to bookmark this link]
Former [2007/05]	METHODS AND COMPOSITIONS FOR REDUCING VIRAL GENOME AMOUNTS IN A TARGET CELL
	[2010/39]
Status	Patent maintained as amended Status updated on 05.02.2016 Database last updated on 07.10.2024
Most recent event Tooltip	05.02.2016	Patent maintained (B2 publication)	published on 09.03.2016 [2016/10]
Applicant(s)	For all designated states The Board of Trustees of the Leland Stanford Junior University 1705 El Camino Real Palo Alto, CA 94306-1106 / US
	[2016/10]
Former [2011/01]	For all designated states The Board of Trustees of the Leland Stanford Junior University 1705 El Camino Real Palo Alto, CA 94306-1106 / US
Former [2007/05]	For all designated states THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 1705 El Camino Real Palo Alto, CA 94306-1106 / US
Inventor(s)	01 / SARNOW, Peter 830 Hamilton Avenue Palo Alto, CA 94301 / US
	02 / JOPLING, Catherine, L. 22 Langton Street San Francisco, CA 94103 / US
	03 / LANCASTER, Alissa, M. 5923 SE 39th Avenue Portland, OR 97202-7509 / US
	[2007/08]
Former [2007/05]	01 / SARNOW, Peter 830 Hamilton Avenue Palo Alto, CA 94301 / US
	02 / JOPLING, Catherine, L. 22 Langton Street San Francisco, CA 94103 / US
	03 / LANCASTER, Alissa, M. 21 Elwood Street Redwood City, CA 94062 / US
Representative(s)	Chapman, Desmond Mark Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB
	[2016/10]
Former [2009/33]	Chapman, Desmond Mark Carpmaels & Ransford 43-45 Bloomsbury Square London WC1A 2RA / GB
Former [2007/05]	Heaton, Joanne Marie Stevens, Hewlett & Perkins 1 St. Augustine's Place Bristol BS1 4UD / GB
Application number, filing date	05749437.9	03.05.2005
	[2007/05]
	WO2005US15264
Priority number, date	US20040568358P	04.05.2004 Original published format: US 568358 P
	[2007/05]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2005107816
	Date:	17.11.2005
	Language:	EN
	[2005/46]
	Type:	A2 Application without search report
	No.:	EP1747023
	Date:	31.01.2007
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 17.11.2005 takes the place of the publication of the European patent application.
	[2007/05]
	Type:	B1 Patent specification
	No.:	EP1747023
	Date:	05.01.2011
	Language:	EN
	[2011/01]
	Type:	B2 New European patent specification
	No.:	EP1747023
	Date:	09.03.2016
	Language:	EN
	[2016/10]
Search report(s)	International search report - published on:	US	23.02.2006
	(Supplementary) European search report - dispatched on:	EP	28.01.2010
Classification	IPC:	C12N15/113, A61K31/712, // A61P31/14	[2010/39]
	CPC:	C12N15/1131 (EP,US); A61K31/7088 (US); A61K45/06 (US); A61K9/0019 (US); A61P1/16 (EP); A61P31/00 (EP); (+) A61P31/12 (EP); A61P31/14 (EP); A61P31/20 (EP); A61P43/00 (EP); C12N15/111 (EP,US); C12N2310/113 (EP,US); C12N2310/14 (EP,US); C12N2310/141 (US); C12N2310/321 (EP,US); C12N2320/31 (US); C12N2320/50 (EP,US); C12N2330/10 (EP,US); C12N2770/24211 (EP,US) (-)
	C-Set:	C12N2310/321, C12N2310/3521 (EP,US)
	Former IPC [2007/05]	A61K48/00
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2016/10]
Former [2007/05]	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR
Title	German:	VERFAHREN UND ZUSAMMENSETZUNGEN ZUR VERRINGERUNG VON HCV VIRUSGENOMMENGEN IN EINER ZIELZELLE	[2010/39]
	English:	METHODS AND COMPOSITIONS FOR REDUCING HCV VIRAL GENOME AMOUNTS IN A TARGET CELL	[2010/39]
	French:	METHODES ET COMPOSITIONS PERMETTANT DE LIMITER LES QUANTITES DE GENOME VIRAL DE HCV DANS UNE CELLULE CIBLE	[2010/39]
	Former [2007/05]	VERFAHREN UND ZUSAMMENSETZUNGEN ZUR VERRINGERUNG VON VIRUSGENOMMENGEN IN EINER ZIELZELLE
	Former [2007/05]	METHODS AND COMPOSITIONS FOR REDUCING VIRAL GENOME AMOUNTS IN A TARGET CELL
	Former [2007/05]	METHODES ET COMPOSITIONS PERMETTANT DE LIMITER LES QUANTITES DE GENOME VIRAL DANS UNE CELLULE CIBLE
Entry into regional phase	25.10.2006	National basic fee paid
	25.10.2006	Search fee paid
	25.10.2006	Designation fee(s) paid
	25.10.2006	Examination fee paid
Examination procedure	25.10.2006	Examination requested [2007/05]
	19.01.2007	Amendment by applicant (claims and/or description)
	25.03.2010	Despatch of a communication from the examining division (Time limit: M04)
	03.08.2010	Reply to a communication from the examining division
	21.09.2010	Communication of intention to grant the patent
	06.10.2010	Observations by third parties
	23.11.2010	Fee for grant paid
	23.11.2010	Fee for publishing/printing paid
Divisional application(s)	EP10196635.6 / EP2338996
	EP12163229.3 Application deemed to be withdrawn : 05.05.2012
	EP12163232.7 / EP2500431
Opposition(s)	Opponent(s)	01 04.10.2011 04.11.2011 ADMISSIBLE Roche Innovation Center Copenhagen A/S Fremtidsvej 3 2970 Hørsholm / DK Opponent's representative D Young & Co LLP Briton House Briton Street Southampton SO14 3EB / GB
		[2015/34]
	Former [2014/52]
	Opponent(s)	01 04.10.2011 04.11.2011 ADMISSIBLE Roche Innovation Center Copenhagen A/S Fremtidsvej 3 2970 Hørsholm / DK Opponent's representative Harding, Charles Thomas D Young & Co LLP 120 Holborn London EC1N 2DY / GB
	Former [2011/45]
	Opponent(s)	01 04.10.2011 Santaris Pharma A/S Kogle Allé 6 2970 Hørsholm / DK Opponent's representative Harding, Charles Thomas D Young & Co LLP 120 Holborn London EC1N 2DY / GB
	11.11.2011	Invitation to proprietor to file observations on the notice of opposition
	23.07.2012	Reply of patent proprietor to notice(s) of opposition
	10.12.2014	Cancellation of oral proceeding that was planned for 17.12.2014
	17.12.2014	Date of oral proceedings
	23.12.2014	Despatch of interlocutory decision in opposition
	30.04.2015	Legal effect of interlocutory decision in opposition
	13.10.2015	Despatch of communication that the patent will be maintained as amended
	11.01.2016	Fee for printing new specification paid
Appeal following opposition	02.03.2015	Appeal received No. T0438/15
	30.04.2015	Result of appeal procedure: appeal of the proprietor withdrawn
Fees paid	Renewal fee
	14.05.2007	Renewal fee patent year 03
	28.05.2008	Renewal fee patent year 04
	27.05.2009	Renewal fee patent year 05
	25.05.2010	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A]WO02081494 (RIBOZYME PHARM INC [US], et al) [A] 1-19 * the whole document *;
		[A]WO03029459 (MAX PLANCK GES ZUR [DE], et al) [A] 1-19 * page 11; sequence 43 * * page 19, line 20 - line 21 * * page 32, line 9 - line 11 * * figure 5 *;
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		[T] - JOPLING CATHERINE L ET AL, "Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA", SCIENCE, (20050901), vol. 309, no. 5740, ISSN 0036-8075, pages 1577 - 1581, XP009109384 DOI: http://dx.doi.org/10.1126/science.1113329
	International search	[AE]US2004175732 (RANA TARIQ M [US]);
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		[AP] - CULLEN B.R., "Derivation and function of small interfering RNAs and microRNAs", VIRUS RESEARCH, (20040601), vol. 102, no. 1, pages 3 - 9, XP002993013 DOI: http://dx.doi.org/10.1016/j.virusres.2004.01.009
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	by applicant	WO02081494
		- MCCAFFREY, A. ET AL., NATURE, vol. 418, no. 6893, pages 38 - 39
		- CHANG ET AL., J. VIROL., (2001), vol. 75, pages 3469 - 3473
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	other	WO9530746
		EP0699751
		US6423489
		WO02081494
		WO03029459
		WO03070750
		WO2005013905
		WO2005013901
		WO2007027894
		US7683036
		- JOPLING C.L. ET AL, "Liver-Specific microRNA122 regulates hepatitis C Viral RNA Abundance", TRANSLATIONAL CONTROL, (20040907), page 124, XP003028324
		- JOPLING CATHERINE L., "Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome", CELL HOST & MICROBE, (20080717), vol. 4, no. 1, pages 77 - 85, XP008100800 DOI: http://dx.doi.org/10.1016/J.CHEM.2008.05.013
		- LAGOS-QUINTANA M; ET AL, "Identification of tissue-specific microRNAs from mouse", CURRENT BIOLOGY, (20020430), vol. 12, no. 9, pages 735 - 739, XP002284274 DOI: http://dx.doi.org/10.1016/S0960-9822(02)00809-6
		- KHAN A.A. ET AL, "Transfection of small RNA's globally perturbs gene regulation by endogenous microRNAs", NATURE BIOTECHNOLOGY, (20090524), pages 1 - 9, XP003028325 DOI: http://dx.doi.org/10.1038/NBT.1543
		- SCOTT DAVIS ET AL, "Potent inhibition of microRNA in vivo without degradation", NUCLEIC ACIDS RESEARCH, (20081116), vol. 37, no. 1, pages 70 - 77, XP003028326 DOI: http://dx.doi.org/10.1093/NAR/GKN904
		- ESAU C.C. ET AL, "Inhibition of microRNA with antisense oligonucleotides", METHODS : A COMPANION TO METHODS IN ENZYMOLOGY, (20071223), vol. 44, no. 1, pages 55 - 60, XP022398580 DOI: http://dx.doi.org/10.1016/j.ymeth.2007.11.001
		- "Guidance for industry Antiviral product development - conducting and submitting virology studies to the agency", FOOD AND DRUG ADMINISTRATION, (200606), pages 1 - 14, XP003028327
		- S.T. CROOKE, "Basic Principle of Antisense Technology", S.T. CROOKE, S.T. CROOKE, Antisense Drug Technology, MARCEL DEKKER INC, pages 1 - 18, ISBN 0-8247-0566-1, XP003028328
		- BIRKE BARTOSCH ET AL, "Cell Entry of Hepatitis C Virus Requires a Set of Co-receptors That Include the CD81 Tetraspanin and the SR-B1 Scavenger Receptor", JOURNAL OF BIOLOGICAL CHEMISTRY, (20031024), vol. 278, no. 43, pages 41624 - 41630, XP007917959 DOI: http://dx.doi.org/10.1074/jbc.M305289200
		- N. PAVIO ET AL, "The hepatitis C virus persistence: how to evade the immune system?", J. BIOSCI., (200304), vol. 28, no. 3, pages 287 - 304, XP003028329 DOI: http://dx.doi.org/10.1007/BF02970148
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	Opposition	WO9530746
		EP0699751
		US6423489

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